Research Output

2019

Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1 P29S Melanoma Cells

Mohan, A. S., Dean, K. M., Isogai, T., Kasitinon, S. Y., Murali, V. S., Roudot, P., Groisman, A., Reed, D. K., Welf, E. S., Han, S. J., Noh, J. & Danuser, G., May 6 2019, In : Developmental cell. 49, 3, p. 444-460.e9

Research output: Contribution to journalArticle

2 Scopus citations

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

Chakraborty, T., Driscoll, M. K., Jeffery, E., Murphy, M. M., Roudot, P., Chang, B. J., Vora, S., Wong, W. M., Nielson, C. D., Zhang, H., Zhemkov, V., Hiremath, C., De La Cruz, E. D., Yi, Y., Bezprozvanny, I., Zhao, H., Tomer, R., Heintzmann, R., Meeks, J. P., Marciano, D. K. & 4 others, Morrison, S. J., Danuser, G., Dean, K. M. & Fiolka, R., Nov 1 2019, In : Nature methods. 16, 11, p. 1109-1113 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nuclear positioning facilitates amoeboid migration along the path of least resistance

Renkawitz, J., Kopf, A., Stopp, J., de Vries, I., Driscoll, M. K., Merrin, J., Hauschild, R., Welf, E. S., Danuser, G., Fiolka, R. & Sixt, M., Apr 25 2019, In : Nature. 568, 7753, p. 546-550 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Robust and automated detection of subcellular morphological motifs in 3D microscopy images

Driscoll, M. K., Welf, E. S., Jamieson, A. R., Dean, K. M., Isogai, T., Fiolka, R. & Danuser, G., Oct 1 2019, In : Nature methods. 16, 10, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- And Src-mediated pathways

Azoitei, M. L., Noh, J., Marston, D. J., Roudot, P., Marshall, C. B., Daugird, T. A., Lisanza, S. L., Sandí, M. J., Ikura, M., Sondek, J., Rottapel, R., Hahn, K. M. & Danuser, G., Sep 2 2019, In : Journal of Cell Biology. 218, 9, p. 3077-3097 21 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Imaging, tracking and computational analyses of virus entry and egress with the cytoskeleton

Wang, I. H., Burckhardt, C. J., Yakimovich, A. & Greber, U. F., Apr 2018, In : Viruses. 10, 4, 166.

Research output: Contribution to journalReview article

Open Access
21 Scopus citations
2017

The nuclear export factor CRM1 controls juxta-nuclear microtubule-dependent virus transport

Wang, I. H., Burckhardt, C. J., Yakimovich, A., Morf, M. K. & Greber, U. F., Jul 1 2017, In : Journal of cell science. 130, 13, p. 2185-2195 11 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2014

Cellular contact guidance through dynamic sensing of nanotopography

Driscoll, M. K., Sun, X., Guven, C., Fourkas, J. T. & Losert, W., Apr 22 2014, In : ACS Nano. 8, 4, p. 3546-3555 10 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Geometry-driven polarity in motile amoeboid cells

Nagel, O., Guven, C., Theves, M., Driscoll, M., Losert, W. & Beta, C., Dec 10 2014, In : PloS one. 9, 12, e113382.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

The interplay of cell-cell and cell-substrate adhesion in collective cell migration

Wang, C., Chowdhury, S., Driscoll, M., Parent, C. A., Gupta, S. K. & Losert, W., Nov 6 2014, In : Journal of the Royal Society Interface. 11, 100, 0684.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2013

From Cellular Characteristics to Disease Diagnosis: Uncovering Phenotypes with Supercells

Candia, J., Maunu, R., Driscoll, M., Biancotto, A., Dagur, P., McCoy, J. P., Sen, H. N., Wei, L., Maritan, A., Cao, K., Nussenblatt, R. B., Banavar, J. R. & Losert, W., Sep 1 2013, In : PLoS Computational Biology. 9, 9, e1003215.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
2012

Automated image analysis of nuclear shape: What can we learn from a prematurely aged cell?

Driscoll, M. K., Albanese, J. L., Xiong, Z. M., Mailman, M., Losert, W. & Cao, K., Feb 2012, In : Aging. 4, 2, p. 119-132 14 p.

Research output: Contribution to journalArticle

35 Scopus citations

Avidity binding of human adenovirus serotypes 3 and 7 to the membrane cofactor CD46 triggers infection

Trinh, H. V., Lesage, G., Chennamparampil, V., Vollenweider, B., Burckhardt, C. J., Schauer, S., Havenga, M., Greber, U. F. & Hemmi, S., Feb 1 2012, In : Journal of virology. 86, 3, p. 1623-1637 15 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Cell-free transmission of human adenovirus by passive mass transfer in cell culture simulated in a computer model

Yakimovich, A., Gumpert, H., Burckhardt, C. J., Lütschg, V. A., Jurgeit, A., Sbalzarini, I. F. & Greber, U. F., Sep 1 2012, In : Journal of virology. 86, 18, p. 10123-10137 15 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations

Cell shape dynamics: From waves to migration

Driscoll, M. K., McCann, C., Kopace, R., Homan, T., Fourkas, J. T., Parent, C. & Losert, W., Mar 1 2012, In : PLoS Computational Biology. 8, 3, e1002392.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
2011

Drifting motions of the adenovirus receptor CAR and immobile integrins initiate virus uncoating and membrane lytic protein exposure

Burckhardt, C. J., Suomalainen, M., Schoenenberger, P., Boucke, K., Hemmi, S. & Greber, U. F., Aug 18 2011, In : Cell Host and Microbe. 10, 2, p. 105-117 13 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations

Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection

Strunze, S., Engelke, M. F., Wang, I. H., Puntener, D., Boucke, K., Schleich, S., Way, M., Schoenenberger, P., Burckhardt, C. J. & Greber, U. F., Sep 15 2011, In : Cell Host and Microbe. 10, 3, p. 210-223 14 p.

Research output: Contribution to journalArticle

Open Access
105 Scopus citations

Local and global measures of shape dynamics

Driscoll, M. K., Fourkas, J. T. & Losert, W., Oct 1 2011, In : Physical Biology. 8, 5, 055001.

Research output: Contribution to journalArticle

17 Scopus citations

The dynactin complex enhances the speed of microtubule-dependent motions of adenovirus both towards and away from the nucleus

Engelke, M. F., Burckhardt, C. J., Morf, M. K. & Greber, U. F., Mar 1 2011, In : Viruses. 3, 3, p. 233-253 21 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations
2009

A stochastic model for microtubule motors describes the in vivo cytoplasmic transport of human adenovirus

Gazzola, M., Burckhardt, C. J., Bayati, B., Engelke, M., Greber, U. F. & Koumoutsakos, P., Dec 1 2009, In : PLoS Computational Biology. 5, 12, e1000623.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Shape reconstruction of subcellular structures from live cell fluorescence microscopy images

Helmuth, J. A., Burckhardt, C. J., Greber, U. F. & Sbalzarini, I. F., Jul 1 2009, In : Journal of Structural Biology. 167, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

The adventures of Dicty, the Dictyostelium cell

Driscoll, M., Kopace, R., Li, L., McCann, C., Watts, J., Fourkas, J. T. & Losert, W., 2009, In : Chaos. 19, 4, 041110.

Research output: Contribution to journalComment/debate

2 Scopus citations

Virus movements on the plasma membrane support infection and transmission between cells

Burckhardt, C. J. & Greber, U. F., Nov 1 2009, In : PLoS pathogens. 5, 11, e1000621.

Research output: Contribution to journalReview article

Open Access
75 Scopus citations
2008

Binary and gray-scale patterning of chemical functionality on polymer films

Li, N., Driscoll, M., Kumi, G., Hernandez, R., Gaskell, K. J., Losert, W. & Fourkas, J. T., Oct 15 2008, In : Journal of the American Chemical Society. 130, 41, p. 13512-13513 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Redox rescues virus from ER trap

Burckhardt, C. J. & Greber, U. F., Jan 1 2008, In : Nature cell biology. 10, 1, p. 9-11 3 p.

Research output: Contribution to journalArticle

7 Scopus citations
2007

A novel supervised trajectory segmentation algorithm identifies distinct types of human adenovirus motion in host cells

Helmuth, J. A., Burckhardt, C. J., Koumoutsakos, P., Greber, U. F. & Sbalzarini, I. F., Sep 1 2007, In : Journal of Structural Biology. 159, 3, p. 347-358 12 p.

Research output: Contribution to journalArticle

65 Scopus citations
2002

Cytoplasmic trafficking of minute virus of mice: Low-pH requirement, routing to late endosomes, and proteasome interaction

Ros, C., Burckhardt, C. J. & Kempf, C., Dec 1 2002, In : Journal of virology. 76, 24, p. 12634-12645 12 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations