Research Output 1995 2019

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2019

Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods

Haas, B. J., Dobin, A., Li, B., Stransky, N., Pochet, N. & Regev, A., Oct 21 2019, In : Genome Biology. 20, 1, 213.

Research output: Contribution to journalArticle

Open Access
accuracy assessment
cancer
Transcriptome
neoplasms
RNA

An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments

Murali, V. S., Chang, B. J., Fiolka, R., Danuser, G., Cobanoglu, M. C. & Welf, E., May 28 2019, In : BMC Cancer. 19, 1, 502.

Research output: Contribution to journalArticle

Open Access
Pharmaceutical Preparations
Melanoma
Mitogen-Activated Protein Kinase Kinases
Cultured Cells
Cell Survival
2 Citations (Scopus)

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

David, A. F., Roudot, P., Legant, W. R., Betzig, E., Danuser, G. & Gerlich, D. W., Jul 1 2019, In : The Journal of cell biology. 218, 7, p. 2150-2168 19 p.

Research output: Contribution to journalArticle

Open Access
Kinetochores
Microtubules
Growth
Microscopy
Spindle Poles
1 Citation (Scopus)

Automated profiling of growth cone heterogeneity defines relations between morphology and motility

Bagonis, M. M., Fusco, L., Pertz, O. & Danuser, G., Jan 7 2019, In : The Journal of cell biology. 218, 1, p. 350-379 30 p.

Research output: Contribution to journalArticle

Growth Cones
Neurites
rho GTP-Binding Proteins
Pseudopodia
Cellular Structures

Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1 P29S Melanoma Cells

Mohan, A. S., Dean, K. M., Isogai, T., Kasitinon, S. Y., Murali, V. S., Roudot, P., Groisman, A., Reed, D. K., Welf, E., Han, S. J., Noh, J. & Danuser, G., May 6 2019, In : Developmental Cell. 49, 3, p. 444-460.e9

Research output: Contribution to journalArticle

Pseudopodia
Actins
Melanoma
Growth
Mutation

GEAMP, a novel gastroesophageal junction carcinoma cell line derived from a malignant pleural effusion

Zhang, W., Williams, T. A., Bhagwath, A. S., Hiermann, J. S., Peacock, C. D., Watkins, D. N., Ding, P., Park, J. Y., Montgomery, E. A., Forastiere, A. A., Jie, C., Cantarel, B. L., Pham, T. H. & Wang, D. H., Jan 1 2019, In : Laboratory Investigation.

Research output: Contribution to journalArticle

Malignant Pleural Effusion
Esophagogastric Junction
Carcinoma
Cell Line
Neoplasms

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Kim, D., Paggi, J. M., Park, C., Bennett, C. & Salzberg, S. L., Aug 1 2019, In : Nature biotechnology. 37, 8, p. 907-915 9 p.

Research output: Contribution to journalArticle

Graphic methods
DNA sequences
Application programs
Genes
Genotype
4 Citations (Scopus)

Landscape of B cell immunity and related immune evasion in human cancers

Hu, X., Zhang, J., Wang, J., Fu, J., Li, T., Zheng, X., Wang, B., Gu, S., Jiang, P., Fan, J., Ying, X., Zhang, J., Carroll, M. C., Wucherpfennig, K. W., Hacohen, N., Zhang, F., Zhang, P., Liu, J. S., Li, B. & Liu, X. S., Jan 1 2019, In : Nature Genetics.

Research output: Contribution to journalArticle

Immune Evasion
Immunity
B-Lymphocytes
Neoplasms
Complementarity Determining Regions

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

Chakraborty, T., Driscoll, M. K., Jeffery, E., Murphy, M. M., Roudot, P., Chang, B. J., Vora, S., Wong, W. M., Nielson, C. D., Zhang, H., Zhemkov, V., Hiremath, C., De La Cruz, E. D., Yi, Y., Bezprozvanny, I., Zhao, H., Tomer, R., Heintzmann, R., Meeks, J. P., Marciano, D. K. & 4 others, Morrison, S. J., Danuser, G., Dean, K. M. & Fiolka, R., Nov 1 2019, In : Nature methods. 16, 11, p. 1109-1113 5 p.

Research output: Contribution to journalArticle

Microscopy
Microscopic examination
Tissue
Light
Immersion
3 Citations (Scopus)

Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn's remission patients despite temporal variations in microbial taxa, genomes, and proteomes

Blakeley-Ruiz, J. A., Erickson, A. R., Cantarel, B., Xiong, W., Adams, R., Jansson, J. K., Fraser, C. M. & Hettich, R. L., Feb 11 2019, In : Microbiome. 7, 1, 18.

Research output: Contribution to journalArticle

Open Access
Microbial Genome
Microbiota
Proteome
Crohn Disease
Microbial Genes

Robust and automated detection of subcellular morphological motifs in 3D microscopy images

Driscoll, M. K., Welf, E. S., Jamieson, A. R., Dean, K. M., Isogai, T., Fiolka, R. & Danuser, G., Oct 1 2019, In : Nature methods. 16, 10, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

Blister
Microscopy
Microscopic examination
Pseudopodia
Morphogenesis

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

Azoitei, M. L., Noh, J., Marston, D. J., Roudot, P., Marshall, C. B., Daugird, T. A., Lisanza, S. L., Sandí, M. J., Ikura, M., Sondek, J., Rottapel, R., Hahn, K. M. & Danuser, G., Sep 2 2019, In : The Journal of cell biology. 218, 9, p. 3077-3097 21 p.

Research output: Contribution to journalArticle

Open Access
Guanine Nucleotide Exchange Factors
Microtubules
rho GTP-Binding Proteins
Guanine
Biosensing Techniques
3 Citations (Scopus)

Universal light-sheet generation with field synthesis

Chang, B. J., Kittisopikul, M., Dean, K. M., Roudot, P., Welf, E. & Fiolka, R., Mar 1 2019, In : Nature methods. 16, 3, p. 235-238 4 p.

Research output: Contribution to journalArticle

Light
Microscopy
Microscopic examination
Photobleaching
Lighting

Using Mothur to Determine Bacterial Community Composition and Structure in 16S Ribosomal RNA Datasets

Chappidi, S., Villa, E. C. & Cantarel, B., Jan 1 2019, In : Current Protocols in Bioinformatics. 67, 1, e83.

Research output: Contribution to journalArticle

Open Access
Genes
Chemical analysis
Bacterial Structures
Archaea
Phylogeny
2018
19 Citations (Scopus)

Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients

Xing, X., Guo, J., Wen, X., Ding, G., Li, B., Dong, B., Feng, Q., Li, S., Zhang, J., Cheng, X., Guo, T., Du, H., Hu, Y., Wang, X., Li, L., Li, Q., Xie, M., Li, L., Gao, X., Shan, F. & 5 others, Li, Z., Ying, X., Zhou, T., Wang, J. & Ji, J., Mar 4 2018, In : OncoImmunology. 7, 3, e1356144.

Research output: Contribution to journalArticle

Stomach Neoplasms
T-Lymphocytes
Proliferating Cell Nuclear Antigen
Neoplasms
Epstein-Barr Virus Infections
4 Citations (Scopus)

A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells

Srinivasan, S., Burckhardt, C. J., Bhave, M., Chen, Z., Chen, P. H., Wang, X., Danuser, G. & Schmid, S. L., Apr 18 2018, In : PLoS Biology. 16, 4, e2005377.

Research output: Contribution to journalArticle

Dynamin I
clathrin
Clathrin
endocytosis
Endocytosis
3 Citations (Scopus)
actin
Actins
image analysis
polymerization
cells

Evaluation of immune repertoire inference methods from RNA-seq data

Hu, X., Zhang, J., Liu, J. S., Li, B. & Liu, X. S., Nov 9 2018, In : Nature Biotechnology. 36, 11, 1 p.

Research output: Contribution to journalArticle

RNA
5 Citations (Scopus)

Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3

Lee, J. J., van de Ven, R. A. H., Zaganjor, E., Ng, M. R., Barakat, A., Demmers, J. J. P. G., Finley, L. W. S., Gonzalez Herrera, K. N., Hung, Y. P., Harris, I. S., Jeong, S. M., Danuser, G., McAllister, S. S. & Haigis, M. C., Jul 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 27, p. 7057-7062 6 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Cell Movement
Reactive Oxygen Species
Epithelial Cells
Breast Neoplasms
4 Citations (Scopus)

Profiling cellular morphodynamics by spatiotemporal spectrum decomposition

Ma, X., Dagliyan, O., Hahn, K. M. & Danuser, G., Aug 1 2018, In : PLoS Computational Biology. 14, 8, e1006321.

Research output: Contribution to journalArticle

morphodynamics
Profiling
decomposition
Hilbert-Huang Transform
Decomposition
53 Citations (Scopus)

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Jiang, P., Gu, S., Pan, D., Fu, J., Sahu, A., Hu, X., Li, Z., Traugh, N., Bu, X., Li, B., Liu, J., Freeman, G. J., Brown, M. A., Wucherpfennig, K. W. & Liu, X. S., Oct 1 2018, In : Nature Medicine. 24, 10, p. 1550-1558 9 p.

Research output: Contribution to journalArticle

T-cells
Immunotherapy
Tumors
T-Lymphocytes
Infiltration
10 Citations (Scopus)

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

Cornwell, M. I., Vangala, M., Taing, L., Herbert, Z., Köster, J., Li, B., Sun, H., Li, T., Zhang, J., Qiu, X., Pun, M., Jeselsohn, R., Brown, M., Liu, X. S. & Long, H. W., Apr 12 2018, In : BMC Bioinformatics. 19, 1, 135.

Research output: Contribution to journalArticle

Workflow
RNA
Work Flow
Visualization
Pipelines
2017
4 Citations (Scopus)

Adaptive robust regression with continuous Gaussian scale mixture errors

Seo, B., Noh, J., Lee, T. & Yoon, Y. J., Mar 1 2017, In : Journal of the Korean Statistical Society. 46, 1, p. 113-125 13 p.

Research output: Contribution to journalArticle

Scale Mixture
Robust Regression
Gaussian Mixture
t-distribution
Outlier
22 Citations (Scopus)

A method for measuring the distribution of the shortest telomeres in cells and tissues

Lai, T. P., Zhang, N., Noh, J., Mender, I., Tedone, E., Huang, E., Wright, W. E., Danuser, G. & Shay, J. W., Dec 1 2017, In : Nature Communications. 8, 1, 1356.

Research output: Contribution to journalArticle

telomeres
Telomere
Assays
Tissue
cells
8 Citations (Scopus)

A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis

Cepika, A. M., Banchereau, R., Segura, E., Ohouo, M., Cantarel, B., Goller, K., Cantrell, V., Ruchaud, E., Gatewood, E., Nguyen, P., Gu, J., Anguiano, E., Zurawski, S., Baisch, J. M., Punaro, M., Baldwin, N., Obermoser, G., Palucka, K., Banchereau, J., Amigorena, S. & 1 others, Pascual, V., Nov 1 2017, In : Journal of Experimental Medicine. 214, 11, p. 3449-3466 18 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Aryl Hydrocarbon Receptors
Monocytes
Interleukin-1
Macrophage Activation Syndrome
11 Citations (Scopus)

Cistrome cancer: A web resource for integrative gene regulation modeling in cancer

Mei, S., Meyer, C. A., Zheng, R., Qin, Q., Wu, Q., Jiang, P., Li, B., Shi, X., Wang, B., Fan, J., Shih, C., Brown, M., Zang, C. & Liu, X. S., Nov 1 2017, In : Cancer Research. 77, 21, p. e19-e22

Research output: Contribution to journalArticle

Genes
Neoplasms
Atlases
Chromatin
Genome
6 Citations (Scopus)

Clonality analysis of synchronous gastro-oesophageal junction carcinoma and distal gastric cancer by whole-exome sequencing

Xing, X., Jia, S., Wu, J., Feng, Q., Dong, B., Li, B., Jia, Y., Shan, F., Li, Y., Zhang, Y., Hu, Y., Wang, X., Liu, X., Yu, W., Zhang, L., Bu, Z., Wu, A., Li, Z. & Ji, J., Oct 1 2017, In : Journal of Pathology. 243, 2, p. 165-175 11 p.

Research output: Contribution to journalArticle

Exome
Stomach Neoplasms
Carcinoma
Neoplasms
CD274 Antigen
8 Citations (Scopus)

Combination therapy targeting BCL6 and phospho-STAT3 defeats intratumor heterogeneity in a subset of non-small cell lung cancers

Deb, D., Rajaram, S., Larsen, J. E., Dospoy, P. D., Marullo, R., Li, L. S., Avila, K., Xue, F., Cerchietti, L., Minna, J. D., Altschuler, S. J. & Wu, L. F., Jun 1 2017, In : Cancer Research. 77, 11, p. 3070-3081 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Oncogenes
Down-Regulation
Neoplasms
MAP Kinase Signaling System
5 Citations (Scopus)

Decoupling global biases and local interactions between cell biological variables

Zaritsky, A., Obolski, U., Gan, Z., Reis, C. R., Kadlecova, Z., Du, Y., Schmid, S. L. & Danuser, G., Mar 13 2017, In : eLife. 6, e22323.

Research output: Contribution to journalArticle

Cell Communication
Cytology
Proxy
Computational methods
Cell Biology
13 Citations (Scopus)

Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration

Zaritsky, A., Tseng, Y. Y., Rabadán, M. A., Krishna, S., Overholtzer, M., Danuser, G. & Hall, A., Jun 1 2017, In : Journal of Cell Biology. 216, 6, p. 1543-1556 14 p.

Research output: Contribution to journalArticle

Guanine Nucleotide Exchange Factors
Cell Movement
GTP Phosphohydrolases
Down-Regulation
Myosin Type II
5 Citations (Scopus)

Functionally pathogenic EARS2 variants in vitro may not manifest a phenotype in vivo

McNeill, N., Nasca, A., Reyes, A., Lemoine, B., Cantarel, B., Vanderver, A., Schiffmann, R. & Ghezzi, D., Jan 1 2017, In : Neurology: Genetics. 3, 4

Research output: Contribution to journalArticle

Phenotype
Exome
Computer Simulation
Mutation
Virulence
3 Citations (Scopus)

Genomic characterization of chromosome translocations in patients with T/myeloid mixed-phenotype acute leukemia

Pallavajjala, A., Kim, D., Li, T., Ghiaur, G., Jones, R. J., Burns, K. H., Salzberg, S. L. & Ning, Y., Sep 8 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-8 8 p.

Research output: Contribution to journalArticle

Leukemia
Chromosomes
Phenotype
Transcriptome
RNA Sequence Analysis
11 Citations (Scopus)

Imaging subcellular dynamics with fast and lightefficient volumetrically parallelized microscopy

Dean, K. M., Roudot, P., Welf, E. S., Pohlkamp, T., Garrelts, G., Herz, J. & Fiolka, R., Feb 20 2017, In : Optica. 4, 2, p. 263-271 9 p.

Research output: Contribution to journalArticle

Microscopic examination
microscopy
Imaging techniques
Fluorescence microscopy
cells
9 Citations (Scopus)

Improved annotation of the insect vector of citrus greening disease: biocuration by a diverse genomics community

Saha, S., Hosmani, P. S., Villalobos-Ayala, K., Miller, S., Shippy, T., Flores, M., Rosendale, A., Cordola, C., Bell, T., Mann, H., DeAvila, G., DeAvila, D., Moore, Z., Buller, K., Ciolkevich, K., Nandyal, S., Mahoney, R., Van Voorhis, J., Dunlevy, M., Farrow, D. & 28 others, Hunter, D., Morgan, T., Shore, K., Guzman, V., Izsak, A., Dixon, D. E., Cridge, A., Cano, L., Cao, X., Jiang, H., Leng, N., Johnson, S., Cantarel, B. L., Richards, S., English, A., Shatters, R. G., Childers, C., Chen, M. J., Hunter, W., Cilia, M., Mueller, L. A., Munoz-Torres, M., Nelson, D., Poelchau, M. F., Benoit, J. B., Wiersma-Koch, H., D'Elia, T. & Brown, S. J., Jan 1 2017, In : Database : the journal of biological databases and curation. 2017

Research output: Contribution to journalArticle

Insect Vectors
greening disease
insect vectors
Citrus
Genomics
7 Citations (Scopus)

Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane

Werbin, J. L., Avendaño, M. S., Becker, V., Jungmann, R., Yin, P., Danuser, G. & Sorger, P. K., Dec 1 2017, In : Scientific Reports. 7, 1, 12150.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Cell Membrane
Ligands
Epidermal Growth Factor
Pharmaceutical Preparations
6 Citations (Scopus)

Piecewise-Stationary Motion Modeling and Iterative Smoothing to Track Heterogeneous Particle Motions in Dense Environments

Roudot, P., Ding, L., Jaqaman, K., Kervrann, C. & Danuser, G., Nov 1 2017, In : IEEE Transactions on Image Processing. 26, 11, p. 5395-5410 16 p., 7938386.

Research output: Contribution to journalArticle

Viruses
Sampling
Imaging techniques
Articular Range of Motion
Microtubules
93 Citations (Scopus)

Resistance to checkpoint blockade therapy through inactivation of antigen presentation

Sade-Feldman, M., Jiao, Y. J., Chen, J. H., Rooney, M. S., Barzily-Rokni, M., Eliane, J. P., Bjorgaard, S. L., Hammond, M. R., Vitzthum, H., Blackmon, S. M., Frederick, D. T., Hazar-Rethinam, M., Nadres, B. A., Van Seventer, E. E., Shukla, S. A., Yizhak, K., Ray, J. P., Rosebrock, D., Livitz, D., Adalsteinsson, V. & 11 others, Getz, G., Duncan, L. M., Li, B., Corcoran, R. B., Lawrence, D. P., Stemmer-Rachamimov, A., Boland, G. M., Landau, D. A., Flaherty, K. T., Sullivan, R. J. & Hacohen, N., Dec 1 2017, In : Nature Communications. 8, 1, 1136.

Research output: Contribution to journalArticle

beta 2-Microglobulin
Antigen Presentation
antigens
deactivation
therapy
6 Citations (Scopus)

Sampling strategies to capture single-cell heterogeneity

Rajaram, S., Heinrich, L. E., Gordan, J. D., Avva, J., Bonness, K. M., Witkiewicz, A. K., Malter, J. S., Atreya, C. E., Warren, R. S., Wu, L. F. & Altschuler, S. J., Oct 1 2017, In : Nature Methods. 14, 10, p. 967-970 4 p.

Research output: Contribution to journalArticle

Sampling
Experiments
Research Personnel
Technology
Population
3 Citations (Scopus)

The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus

Sun, Z., Ke, X., Salzberg, S. L., Kim, D., Antonescu, V., Cheng, Y., Huang, B., Song, J. H., Abraham, J. M., Ibrahim, S., Tian, H. & Meltzer, S. J., May 1 2017, In : Cancer. 123, 9, p. 1507-1515 9 p.

Research output: Contribution to journalArticle

Cytoplasmic and Nuclear Receptors
Colonic Neoplasms
RNA Sequence Analysis
Epithelium
Neoplasms
69 Citations (Scopus)

TIMER: A web server for comprehensive analysis of tumor-infiltrating immune cells

Li, T., Fan, J., Wang, B., Traugh, N., Chen, Q., Liu, J. S., Li, B. & Liu, X. S., Nov 1 2017, In : Cancer Research. 77, 21, p. e108-e110

Research output: Contribution to journalArticle

Neoplasms
Antigen-Antibody Complex
Immunotherapy
Immune System
Research Personnel
18 Citations (Scopus)

Vimentin fibers orient traction stress

Costigliola, N., Ding, L., Burckhardt, C. J., Han, S. J., Gutierrez, E., Mota, A., Groisman, A., Mitchison, T. J. & Danuser, G., May 16 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 20, p. 5195-5200 6 p.

Research output: Contribution to journalArticle

Traction
Vimentin
Actins
Cell Movement
Fibroblasts
11 Citations (Scopus)

Whole-genome sequencing accurately identifies resistance to extended-spectrum β-lactams for major gram-negative bacterial pathogens

Shelburne, S. A., Kim, J., Munita, J. M., Sahasrabhojane, P., Shields, R. K., Press, E. G., Li, X., Arias, C. A., Cantarel, B., Jiang, Y., Kim, M. S., Aitken, S. L. & Greenberg, D. E., 2017, In : Clinical Infectious Diseases. 65, 5, p. 738-745 8 p.

Research output: Contribution to journalArticle

Lactams
Genome
Polymerase Chain Reaction
Mutation
Microbial Sensitivity Tests
2016
70 Citations (Scopus)

A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo

Chu, J., Oh, Y., Sens, A., Ataie, N., Dana, H., Macklin, J. J., Laviv, T., Welf, E. S., Dean, K. M., Zhang, F., Kim, B. B., Tang, C. T., Hu, M., Baird, M. A., Davidson, M. W., Kay, M. A., Fiolka, R., Yasuda, R., Kim, D. S., Ng, H. L. & 1 others, Lin, M. Z., Jul 1 2016, In : Nature Biotechnology. 34, 7, p. 760-767 8 p.

Research output: Contribution to journalArticle

Bioluminescence
Microscopy
Microscopic examination
Tissue
Proteins
110 Citations (Scopus)

Centrifuge: Rapid and sensitive classification of metagenomic sequences

Kim, D., Song, L., Breitwieser, F. P. & Salzberg, S. L., Dec 1 2016, In : Genome Research. 26, 12, p. 1721-1729 9 p.

Research output: Contribution to journalArticle

Metagenomics
Archaeal Genome
High-Throughput Nucleotide Sequencing
Databases
Datasets
155 Citations (Scopus)

Comprehensive analyses of tumor immunity: Implications for cancer immunotherapy

Li, B., Severson, E., Pignon, J. C., Zhao, H., Li, T., Novak, J., Jiang, P., Shen, H., Aster, J. C., Rodig, S., Signoretti, S., Liu, J. S. & Liu, X. S., Aug 22 2016, In : Genome Biology. 17, 1, 174.

Research output: Contribution to journalArticle

immunotherapy
immunity
tumor
Immunotherapy
Immunity
17 Citations (Scopus)

Diagonally Scanned Light-Sheet Microscopy for Fast Volumetric Imaging of Adherent Cells

Dean, K. M., Roudot, P., Reis, C. R., Welf, E. S., Mettlen, M. & Fiolka, R., Mar 29 2016, In : Biophysical Journal. 110, 6, p. 1456-1465 10 p.

Research output: Contribution to journalArticle

Microscopy
Light
Clathrin
Glass
Transport Vesicles
106 Citations (Scopus)

Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

Ramirez, M., Rajaram, S., Steininger, R. J., Osipchuk, D., Roth, M. A., Morinishi, L. S., Evans, L., Ji, W., Hsu, C. H., Thurley, K., Wei, S., Zhou, A., Koduru, P. R., Posner, B. A., Wu, L. F. & Altschuler, S. J., Feb 19 2016, In : Nature Communications. 7, 10690.

Research output: Contribution to journalArticle

Drug Resistance
drugs
cancer
cells
Pharmaceutical Preparations
18 Citations (Scopus)

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions

Hodgson, L., Spiering, DÃ., Sabouri-Ghomi, M., Dagliyan, O., Der Mardirossian, CÃ., Danuser, G. & MHahn, K., Oct 1 2016, In : Nature Chemical Biology. 12, 10, p. 802-809 8 p.

Research output: Contribution to journalArticle

Guanine Nucleotide Dissociation Inhibitors
Fluorescence Resonance Energy Transfer
GTP Phosphohydrolases
rho GTP-Binding Proteins
Biosensing Techniques
15 Citations (Scopus)

High-dimensional genomic data bias correction and data integration using MANCIE

Zang, C., Wang, T., Deng, K., Li, B., Hu, S., Qin, Q., Xiao, T., Zhang, S., Meyer, C. A., He, H. H., Brown, M., Liu, J. S., Xie, Y. & Liu, X. S., Apr 13 2016, In : Nature Communications. 7, 11305.

Research output: Contribution to journalArticle

data integration
Data integration
cancer
Encyclopedias
augmentation
121 Citations (Scopus)

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

Ohne, Y., Silver, J. S., Thompson-Snipes, L. A., Collet, M. A., Blanck, J. P., Cantarel, B. L., Copenhaver, A. M., Humbles, A. A. & Liu, Y. J., May 19 2016, In : Nature Immunology. 17, 6, p. 646-655 10 p.

Research output: Contribution to journalArticle

Interleukin-1
Lymphocytes
Cytokine Receptors
Interleukin-12
Cytokines