Biophysics

Research Output 1979 2019

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2018

Günter Blobel 1936–2018

Chook, Y. M., Fontoura, B. M. A. & Rout, M. P., Apr 2 2018, (Accepted/In press) In : Nature Structural and Molecular Biology. p. 1-2 2 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265

White, J., Dhingra, S. K., Deng, X., El Mazouni, F., Lee, M. C. S., Afanador, G. A., Lawong, A., Tomchick, D. R., Ng, C. L., Bath, J., Rathod, P. K., Fidock, D. A. & Phillips, M. A., Jan 1 2018, (Accepted/In press) In : ACS Infectious Diseases.

Research output: Contribution to journal › Article

Plasmodium falciparum
Point Mutation
Parasites
Malaria
Mutation
8 Citations (Scopus)

Intracellular chloride and scaffold protein mo25 cooperatively regulate transepithelial ion transport through WNK signaling in the malpighian tubule

Sun, Q., Wu, Y., Jonusaite, S., Pleinis, J. M., Humphreys, J. M., He, H., Schellinger, J. N., Akella, R., Stenesen, D., Krämer, H., Goldsmith, E. J. & Rodan, A. R., May 1 2018, In : Journal of the American Society of Nephrology. 29, 5, p. 1449-1461 13 p.

Research output: Contribution to journal › Article

Malpighian Tubules
Ion Transport
Drosophila
Chlorides
Drosophila Proteins
7 Citations (Scopus)

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity

Ye, R., Gordillo, R., Shao, M., Onodera, T., Chen, Z., Chen, S., Lin, X., SoRelle, J. A., Li, X., Tang, M., Keller, M. P., Kuliawat, R., Attie, A. D., Gupta, R. K., Holland, W. L., Beutler, B. A., Herz, J. & Scherer, P. E., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 1178-1189 12 p.

Research output: Contribution to journal › Article

Low Density Lipoprotein Receptor-Related Protein-1
Lipid Metabolism
Obesity
Insulin
Diet
54 Citations (Scopus)

Intrinsically Disordered Regions Can Contribute Promiscuous Interactions to RNP Granule Assembly

Protter, D. S. W., Rao, B. S., Van Treeck, B., Lin, Y., Mizoue, L., Rosen, M. K. & Parker, R., Feb 6 2018, In : Cell Reports. 22, 6, p. 1401-1412 12 p.

Research output: Contribution to journal › Article

Proteins
Eukaryotic Cells
RNA
Phase separation
Intrinsically Disordered Proteins
15 Citations (Scopus)

Mechanism of neurotransmitter release coming into focus

Rizo-Rey, J., Jan 1 2018, (Accepted/In press) In : Protein Science.

Research output: Contribution to journal › Article

Neurotransmitter Agents
Membrane Fusion
Syntaxin 1
Proteins
Fusion reactions
42 Citations (Scopus)

Microtubule dynamics: an interplay of biochemistry and mechanics

Brouhard, G. J. & Rice, L. M., Apr 19 2018, (Accepted/In press) In : Nature Reviews Molecular Cell Biology. p. 1-13 13 p.

Research output: Contribution to journal › Article

Mechanics
Microtubules
Biochemistry
Tubulin
Microtubule-Associated Proteins
7 Citations (Scopus)

Multistep Track Segmentation and Motion Classification for Transient Mobility Analysis

Vega, A. R., Freeman, S. A., Grinstein, S. & Jaqaman, K., Mar 13 2018, In : Biophysical Journal. 114, 5, p. 1018-1025 8 p.

Research output: Contribution to journal › Article

Spectrum Analysis
Actins
Macrophages
Observation
Proteins
40 Citations (Scopus)

Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites

Yoshizawa, T., Ali, R., Jiou, J., Fung, H. Y. J., Burke, K. A., Kim, S. J., Lin, Y., Peeples, W. B., Saltzberg, D., Soniat, M., Baumhardt, J. M., Oldenbourg, R., Sali, A., Fawzi, N. L., Rosen, M. K. & Chook, Y. M., Jan 1 2018, (Accepted/In press) In : Cell.

Research output: Contribution to journal › Article

Karyopherins
Cell Nucleus Active Transport
Cytoplasmic and Nuclear Receptors
Phase separation
Sarcoma
62 Citations (Scopus)

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

Guo, L., Kim, H. J., Wang, H., Monaghan, J., Freyermuth, F., Sung, J. C., O'Donovan, K., Fare, C. M., Diaz, Z., Singh, N., Zhang, Z. C., Coughlin, M., Sweeny, E. A., DeSantis, M. E., Jackrel, M. E., Rodell, C. B., Burdick, J. A., King, O. D., Gitler, A. D., Lagier-Tourenne, C. & 4 others, Pandey, U. B., Chook, Y. M., Taylor, J. P. & Shorter, J., Apr 19 2018, In : Cell. 173, 3, p. 677-692.e20

Research output: Contribution to journal › Article

Karyopherins
RNA-Binding Proteins
Cell Nucleus Active Transport
Prions
Phase Transition
6 Citations (Scopus)

On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies

Clark, L., Dikiy, I., Rosenbaum, D. M. & Gardner, K. H., Aug 1 2018, In : Journal of Biomolecular NMR. 71, 4, p. 203-211 9 p.

Research output: Contribution to journal › Article

Pichia
G-Protein-Coupled Receptors
Labeling
Membrane Proteins
Nuclear magnetic resonance
14 Citations (Scopus)

Protein AMPylation by an Evolutionarily Conserved Pseudokinase

Sreelatha, A., Yee, S. S., Lopez, V. A., Park, B. C., Kinch, L. N., Pilch, S., Servage, K. A., Zhang, J., Jiou, J., Karasiewicz-Urbańska, M., Łobocka, M., Grishin, N. V., Orth, K. A., Kucharczyk, R., Pawłowski, K., Tomchick, D. R. & Tagliabracci, V. S., Oct 18 2018, In : Cell. 175, 3, p. 809-821.e19

Research output: Contribution to journal › Article

Selenoproteins
Protein Kinases
Proteins
Adenosine Triphosphate
Catalysis
6 Citations (Scopus)

Proteins that control the geometry of microtubules at the ends of cilia

Louka, P., Vasudevan, K. K., Guha, M., Joachimiak, E., Wloga, D., Tomasi, R. F. X., Baroud, C. N., Dupuis‑Williams, P., Galati, D. F., Pearson, C. G., Rice, L. M., Moresco, J. J., Yates, J. R., Jiang, Y. Y., Lechtreck, K., Dentler, W. & Gaertig, J., Dec 1 2018, In : Journal of Cell Biology. 217, 12, p. 4298-4313 16 p.

Research output: Contribution to journal › Article

Cilia
Microtubules
Basal Bodies
Axoneme
Proteins
3 Citations (Scopus)

Real-space analysis of radiation-induced specific changes with independent component analysis

Borek, D., Bromberg, R., Hattne, J. & Otwinowski, Z., Mar 1 2018, In : Journal of Synchrotron Radiation. 25, 2, p. 451-467 17 p.

Research output: Contribution to journal › Article

Independent component analysis
Radiation
radiation
Radiation damage
Temperature
11 Citations (Scopus)

RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes

de Jong, A. P. H., Roggero, C. M., Ho, M. R., Wong, M. Y., Brautigam, C. A., Rizo-Rey, J. & Kaeser, P. S., Jan 1 2018, (Accepted/In press) In : Neuron.

Research output: Contribution to journal › Article

Synaptic Vesicles
Exocytosis
Membranes
Phospholipids
Action Potentials
3 Citations (Scopus)

Roles of the fission yeast UNC-13/Munc13 protein Ync13 in late stages of cytokinesis

Zhu, Y. H., Hyun, J., Pan, Y. Z., Hopper, J. E., Rizo-Rey, J. & Wu, J. Q., Sep 15 2018, In : Molecular Biology of the Cell. 29, 19, p. 2259-2279 21 p.

Research output: Contribution to journal › Article

Cytokinesis
Schizosaccharomyces
Exocytosis
Cell Wall
Proteins
1 Citation (Scopus)

Searching ECOD for Homologous Domains by Sequence and Structure

Schaeffer, R. D., Liao, Y. & Grishin, N. V., Mar 1 2018, In : Current Protocols in Bioinformatics. 61, 1, e45.

Research output: Contribution to journal › Article

Sequence Homology
Proteins
Databases
Functional analysis
Information Storage and Retrieval
4 Citations (Scopus)

Species-Selective Pyrimidineamine Inhibitors of Trypanosoma brucei S-Adenosylmethionine Decarboxylase

Volkov, O. A., Brockway, A. J., Wring, S. A., Peel, M., Chen, Z., Phillips, M. A. & De Brabander, J. K., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 1182-1203 22 p.

Research output: Contribution to journal › Article

Adenosylmethionine Decarboxylase
Trypanosoma brucei brucei
African Trypanosomiasis
Parasites
Enzymes
7 Citations (Scopus)

Structural and functional differences between porcine brain and budding yeast microtubules

Howes, S. C., Geyer, E. A., LaFrance, B., Zhang, R., Kellogg, E. H., Westermann, S., Rice, L. M. & Nogales, E., Jan 1 2018, (Accepted/In press) In : Cell Cycle. p. 1-10 10 p.

Research output: Contribution to journal › Article

Saccharomycetales
Tubulin
Microtubules
Swine
Yeasts
1 Citation (Scopus)

Structural–functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression

Zhang, K., Shang, G., Padavannil, A., Wang, J., Sakthivel, R., Chen, X., Kim, M., Thompson, M. G., García-Sastre, A., Lynch, K. W., Chen, Z., Chook, Y. M. & Fontoura, B. M., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. E12218-E12227

Research output: Contribution to journal › Article

Protein Splicing
Viral Genes
Gene Expression
Messenger RNA
Cell Nucleus Active Transport
34 Citations (Scopus)

Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel

She, J., Guo, J., Chen, Q., Zeng, W., Jiang, Y. & Bai, X. C., Apr 5 2018, In : Nature. 556, 7699, p. 130-134 5 p.

Research output: Contribution to journal › Article

Phospholipids
Ion Channels
Microscopy
Ligands
Cryoelectron Microscopy
3 Citations (Scopus)

The Bear Giant-Skipper genome suggests genetic adaptations to living inside yucca roots

Cong, Q., Li, W., Borek, D., Otwinowski, Z. & Grishin, N. V., Jan 1 2018, (Accepted/In press) In : Molecular Genetics and Genomics.

Research output: Contribution to journal › Article

Yucca
Ursidae
Genome
Agave
Poaceae
29 Citations (Scopus)

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

Freeman, S. A., Vega, A., Riedl, M., Collins, R. F., Ostrowski, P. P., Woods, E. C., Bertozzi, C. R., Tammi, M. I., Lidke, D. S., Johnson, P., Mayor, S., Jaqaman, K. & Grinstein, S., Jan 11 2018, In : Cell. 172, 1-2, p. 305-312.e10

Research output: Contribution to journal › Article

Actin Cytoskeleton
Skeleton
Actins
Immobilized Proteins
Fc Receptors
2 Citations (Scopus)

Trypanosomatid Deoxyhypusine Synthase Activity Is Dependent on Shared Active-Site Complementation between Pseudoenzyme Paralogs

Afanador, G. A., Tomchick, D. R. & Phillips, M. A., Nov 6 2018, In : Structure. 26, 11, p. 1499-1512.e5

Research output: Contribution to journal › Article

Catalytic Domain
Trypanosoma brucei brucei
X-Rays
Neglected Diseases
Eukaryotic Initiation Factors
4 Citations (Scopus)

Using two-site binding models to analyze microscale thermophoresis data

Tso, S. C., Chen, Q., Vishnivetskiy, S. A., Gurevich, V. V., Iverson, T. M. & Brautigam, C. A., Jan 1 2018, In : Analytical Biochemistry. 540-541, p. 64-75 12 p.

Research output: Contribution to journal › Article

Thermophoresis
Binding Sites
Molecules
24 Citations (Scopus)

Who's In and Who's Out—Compositional Control of Biomolecular Condensates

Ditlev, J. A., Case, L. B. & Rosen, M. K., Jan 1 2018, (Accepted/In press) In : Journal of Molecular Biology.

Research output: Contribution to journal › Article

Membranes
Eukaryotic Cells
Static Electricity
Hydrophobic and Hydrophilic Interactions
Base Pairing
2017
5 Citations (Scopus)

Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation

Huang, W. Y. C., Ditlev, J. A., Chiang, H. K., Rosen, M. K. & Groves, J. T., Dec 13 2017, In : Journal of the American Chemical Society. 139, 49, p. 18009-18015 7 p.

Research output: Contribution to journal › Article

Intrinsically Disordered Proteins
Phosphorylation
T-cells
Scaffolds (biology)
Scaffolds
18 Citations (Scopus)

A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity

Arellano-Santoyo, H., Geyer, E. A., Stokasimov, E., Chen, G. Y., Su, X., Hancock, W., Rice, L. M. & Pellman, D., Jul 10 2017, In : Developmental Cell. 42, 1, p. 37-51.e8

Research output: Contribution to journal › Article

Kinesin
Tubulin
Microtubules
Switches
Depolymerization
16 Citations (Scopus)

Autoinhibition of munc18-1 modulates synaptobrevin binding and helps to enable munc13-dependent regulation of membrane fusion

Sitarska, E., Xu, J., Park, S., Liu, X., Quade, B., Stepien, K., Sugita, K., Brautigam, C. A., Sugita, S. & Rizo-Rey, J., May 6 2017, In : eLife. 6, e24278.

Research output: Contribution to journal › Article

Vesicle-Associated Membrane Protein 1
R-SNARE Proteins
Membrane Fusion
Fusion reactions
Membranes
498 Citations (Scopus)

Biomolecular condensates: organizers of cellular biochemistry

Banani, S. F., Lee, H. O., Hyman, A. A. & Rosen, M. K., Feb 22 2017, (Accepted/In press) In : Nature Reviews Molecular Cell Biology.

Research output: Contribution to journal › Article

Eukaryotic Cells
Ribosomes
Biochemistry
Nucleic Acids
DNA Damage
8 Citations (Scopus)

Complete genome of achalarus lyciades, the first representative of the eudaminae subfamily of skippers

Shen, J., Cong, Q., Borek, D., Otwinowski, Z. & Grishin, N. V., Aug 1 2017, In : Current Genomics. 18, 4, p. 366-374 9 p.

Research output: Contribution to journal › Article

Genome
Poaceae
Charadriiformes
Opsins
Cellulases
23 Citations (Scopus)

Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution

Boland, A., Martin, T. G., Zhang, Z., Yang, J., Bai, X. C., Chang, L., Scheres, S. H. W. & Barford, D., Apr 1 2017, In : Nature Structural and Molecular Biology. 24, 4, p. 414-418 5 p.

Research output: Contribution to journal › Article

Separase
Securin
Catalytic Domain
Peptide Hydrolases
Cryoelectron Microscopy
1 Citation (Scopus)

Crystal Structure of the CLOCK Transactivation Domain Exon19 in Complex with a Repressor

Hou, Z., Su, L., Pei, J., Grishin, N. V. & Zhang, H., 2017, (Accepted/In press) In : Structure.

Research output: Contribution to journal › Article

Chlorpropham
Transcriptional Activation
Invertebrates
Protein Databases
Mutagenesis
12 Citations (Scopus)

Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips

Driver, J. W., Geyer, E. A., Bailey, M. E., Rice, L. M. & Asbury, C. L., Jun 19 2017, In : eLife. 6, e28433.

Research output: Contribution to journal › Article

Kinetochores
Tubulin
Strain energy
Microtubules
Elasticity
4 Citations (Scopus)

Direct regulation of p190RhoGEF by activated Rho and Rac GTPases

Dada, O., Gutowski, S., Brautigam, C. A., Chen, Z. & Sternweis, P. C., Jan 1 2017, (Accepted/In press) In : Journal of Structural Biology.

Research output: Contribution to journal › Article

Rho Guanine Nucleotide Exchange Factors
rho GTP-Binding Proteins
Cell Shape
Cell Movement
Nucleotides
16 Citations (Scopus)

ECOD: New developments in the evolutionary classification of domains

Dustin Schaeffer, R., Liao, Y., Cheng, H. & Grishin, N. V., Jan 1 2017, In : Nucleic Acids Research. 45, D1, p. D296-D302

Research output: Contribution to journal › Article

Databases
Proteins
Protein Domains
Direction compound
10 Citations (Scopus)

Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release

Voleti, R., Tomchick, D. R., Südhof, T. C. & Rizo-Rey, J., Oct 3 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. E8518-E8527

Research output: Contribution to journal › Article

Synaptotagmins
Neurotransmitter Agents
Membranes
Phosphatidylinositol 4,5-Diphosphate
Calorimetry
3 Citations (Scopus)

Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum

Brautigam, C. A., Deka, R. K., Liu, W. Z., Tomchick, D. R. & Norgard, M. V., Apr 1 2017, In : Protein Science. 26, 4, p. 847-856 10 p.

Research output: Contribution to journal › Article

Periplasmic Binding Proteins
Treponema pallidum
Carrier Proteins
Crystal structure
Ligands
21 Citations (Scopus)

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming

Camacho, M., Basu, J., Trimbuch, T., Chang, S., Pulido-Lozano, C., Chang, S. S., Duluvova, I., Abo-Rady, M., Rizo-Rey, J. & Rosenmund, C., Jan 1 2017, In : Nature Communications. 8, 15293.

Research output: Contribution to journal › Article

priming
Reaction injection molding
Synaptic Vesicles
Electrophysiology
Neurotransmitter Agents
70 Citations (Scopus)

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

Harmon, T. S., Holehouse, A. S., Rosen, M. K. & Pappu, R. V., Nov 1 2017, In : eLife. 6, e30294.

Research output: Contribution to journal › Article

Gelation
Phase separation
Proteins
Phase Transition
Phase transitions
51 Citations (Scopus)

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Lin, Y., Currie, S. L. & Rosen, M. K., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 19110-19120 11 p.

Research output: Contribution to journal › Article

Phase separation
Tyrosine
Modulation
RNA
Proline
24 Citations (Scopus)

Ligand modulation of sidechain dynamics in a wild-type human GPCR

Clark, L. D., Dikiy, I., Chapman, K., Rödström, K. E. J., Aramini, J., LeVine, M. V., Khelashvili, G., Rasmussen, S. G. F., Gardner, K. H. & Rosenbaum, D. M., Oct 6 2017, In : eLife. 6, e28505.

Research output: Contribution to journal › Article

Nuclear magnetic resonance
Modulation
Ligands
Adenosine-5'-(N-ethylcarboxamide)
Isoleucine
6 Citations (Scopus)

Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing

Brulotte, M. L., Jeong, B. C., Li, F., Li, B., Yu, E. B., Wu, Q., Brautigam, C. A., Yu, H. & Luo, X., Dec 1 2017, In : Nature Communications. 8, 1, 1956.

Research output: Contribution to journal › Article

Anaphase-Promoting Complex-Cyclosome
M Phase Cell Cycle Checkpoints
spindles
Mad2 Proteins
proteins
23 Citations (Scopus)

Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme

Li, Y., Zhou, M., Hu, Q., Bai, X. C., Huang, W., Scheres, S. H. W. & Shi, Y., Feb 14 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. 1542-1547 6 p.

Research output: Contribution to journal › Article

Apoptosomes
Holoenzymes
Caspase 9
Initiator Caspases
Effector Caspases
34 Citations (Scopus)

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN

Xu, J., Camacho, M., Xu, Y., Esser, V., Liu, X., Trimbuch, T., Pan, Y. Z., Ma, C., Tomchick, D. R., Rosenmund, C. & Rizo-Rey, J., Feb 8 2017, In : eLife. 6, e22567.

Research output: Contribution to journal › Article

Cell membranes
Plasticity
Neurotransmitter Agents
Crystal structure
Cell Membrane
30 Citations (Scopus)

Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis

Wong, W., Bai, X. C., Sleebs, B. E., Triglia, T., Brown, A., Thompson, J. K., Jackson, K. E., Hanssen, E., Marapana, D. S., Fernandez, I. S., Ralph, S. A., Cowman, A. F., Scheres, S. H. W. & Baum, J., Mar 13 2017, In : Nature Microbiology. 2, 17031.

Research output: Contribution to journal › Article

Mefloquine
Plasmodium falciparum
Ribosomes
Cryoelectron Microscopy
Parasites
18 Citations (Scopus)

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5

Obayashi, E., Luna, R. E., Nagata, T., Martin-Marcos, P., Hiraishi, H., Singh, C. R., Erzberger, J. P., Zhang, F., Arthanari, H., Morris, J., Pellarin, R., Moore, C., Harmon, I., Papadopoulos, E., Yoshida, H., Nasr, M. L., Unzai, S., Thompson, B., Aube, E., Hustak, S. & 8 others, Stengel, F., Dagraca, E., Ananbandam, A., Gao, P., Urano, T., Hinnebusch, A. G., Wagner, G. & Asano, K., Mar 14 2017, In : Cell Reports. 18, 11, p. 2651-2663 13 p.

Research output: Contribution to journal › Article

Initiator Codon
Ribosomes
5-chloro-3-tert-butyl-2'-chloro-4'-nitrosalicylanilide
Scanning
Messenger RNA
16 Citations (Scopus)

Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals

Fung, H. Y. J., Fu, S. C. & Chook, Y. M., Mar 10 2017, In : eLife. 6, e23961.

Research output: Contribution to journal › Article

Nuclear Export Signals
Cell Nucleus Active Transport
Cytoplasmic and Nuclear Receptors
Conformations
Peptides
6 Citations (Scopus)

Piecewise-Stationary Motion Modeling and Iterative Smoothing to Track Heterogeneous Particle Motions in Dense Environments

Roudot, P., Ding, L., Jaqaman, K., Kervrann, C. & Danuser, G., Nov 1 2017, In : IEEE Transactions on Image Processing. 26, 11, p. 5395-5410 16 p., 7938386.

Research output: Contribution to journal › Article

Viruses
Sampling
Imaging techniques
Articular Range of Motion
Microtubules
18 Citations (Scopus)

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

Chen, B., Chou, H. T., Brautigam, C. A., Xing, W., Yang, S., Henry, L., Doolittle, L. K., Walz, T. & Rosen, M. K., Sep 26 2017, In : eLife. 6, e29795.

Research output: Contribution to journal › Article

GTP Phosphohydrolases
Actins
Actin-Related Protein 2-3 Complex
Binding Sites
Cryoelectron Microscopy