Cell Biology - Division C

Research Output

2018

Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1

Trinh, M. N., Brown, M. S., Seemann, J., Goldstein, J. L. & Lu, F., Jul 26 2018, In : eLife. 7, e38564.

Research output: Contribution to journalArticle

6 Scopus citations
2017
26 Scopus citations

Cell Labeling with Magneto-Endosymbionts and the Dissection of the Subcellular Location, Fate, and Host Cell Interactions

Lee, K. R., Wakeel, A., Chakraborty, P., Foote, C. S., Kajiura, L., Barrozo, J. C., Chan, A. C., Bazarov, A. V., Spitler, R., Kutny, P. M., Denegre, J. M., Taft, R. A., Seemann, J., Rice, B. W., Contag, C. H., Rutt, B. K. & Bell, C. B., Jun 19 2017, (Accepted/In press) In : Molecular Imaging and Biology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Golgi ribbon disassembly during mitosis, differentiation and disease progression

Wei, J. H. & Seemann, J., Aug 1 2017, In : Current Opinion in Cell Biology. 47, p. 43-51 9 p.

Research output: Contribution to journalReview article

21 Scopus citations
2016

Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi

Schumacher, M. M., Jun, D. J., Jo, Y., Seemann, J. & DeBose-Boyd, R. A., Jul 1 2016, In : Journal of Lipid Research. 57, 7, p. 1286-1299 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
22 Scopus citations
2015

GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules

Wei, J. H., Zhang, Z. C., Wynn, R. M. & Seemann, J., Jul 18 2015, In : Cell. 162, 2, p. 287-299 13 p., 8260.

Research output: Contribution to journalArticle

50 Scopus citations

Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo

Moreira, T. G., Zhang, L., Shaulov, L., Harel, A., Kuss, S. K., Williams, J., Shelton, J., Somatilaka, B., Seemann, J., Yang, J., Sakthivel, R., Nussenzveig, D. R., Faria, A. M. C. & Fontoura, B. M. A., Dec 3 2015, In : Scientific Reports. 5, 17655.

Research output: Contribution to journalArticle

8 Scopus citations

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

Schumacher, M. M., Elsabrouty, R., Seemann, J., Jo, Y. & DeBose-Boyd, R. A., Mar 5 2015, In : eLife. 2015, 4, e05560.

Research output: Contribution to journalArticle

32 Scopus citations
2014
27 Scopus citations
2013

Chemical principles for the design of a novel fluorescent probe with high cancer-targeting selectivity and sensitivity

Kang, C. C., Huang, W. C., Kouh, C. W., Wang, Z. F., Cho, C. C., Chang, C. C., Wang, C. L., Chang, T. C., Seemann, J. & Huang, L. J. S., Oct 1 2013, In : Integrative Biology (United Kingdom). 5, 10, p. 1217-1228 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Point mutation in luminal Loop 7 of scap protein blocks interaction with Loop 1 and abolishes movement to Golgi

Zhang, Y., Motamed, M., Seemann, J., Brown, M. S. & Goldstein, J. L., May 17 2013, In : Journal of Biological Chemistry. 288, 20, p. 14059-14067 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2012

Modular organization of the mammalian Golgi apparatus

Nakamura, N., Wei, J. H. & Seemann, J., Aug 1 2012, In : Current Opinion in Cell Biology. 24, 4, p. 467-474 8 p.

Research output: Contribution to journalReview article

37 Scopus citations
2011

Golgi biogenesis

Wang, Y. & Seemann, J., Oct 2011, In : Cold Spring Harbor Perspectives in Biology. 3, 10, p. 1-12 12 p.

Research output: Contribution to journalArticle

40 Scopus citations

Identification of luminal loop 1 of scap protein as the sterol sensor that maintains cholesterol homeostasis

Motamed, M., Zhang, Y., Wang, M. L., Seemann, J., Kwon, H. J., Goldstein, J. L. & Brown, M. S., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 18002-18012 11 p.

Research output: Contribution to journalArticle

53 Scopus citations

The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells

Denard, B., Seemann, J., Chen, Q., Gay, A., Huang, H., Chen, Y. & Ye, J., Jul 21 2011, In : Cell Host and Microbe. 10, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
2010

A regulating role of the JAK2 FERM domain in hyperactivation of JAK2(V617F)

Zhao, L., Ma, Y., Seemann, J. & Huang, L. J. S., Feb 15 2010, In : Biochemical Journal. 426, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

CDK5RAP2 regulates centriole engagement and cohesion in mice

Barrera, J. A., Kao, L. R., Hammer, R. E., Seemann, J., Fuchs, J. L. & Megraw, T. L., Mar 16 2010, In : Developmental cell. 18, 6, p. 913-926 14 p.

Research output: Contribution to journalArticle

92 Scopus citations

Nakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cells

Wei, J. H. & Seemann, J., Dec 1 2010, In : Molecular Cancer Therapeutics. 9, 12, p. 3375-3385 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices

Miron-Mendoza, M., Seemann, J. & Grinnell, F., Sep 1 2010, In : Biomaterials. 31, 25, p. 6425-6435 11 p.

Research output: Contribution to journalArticle

147 Scopus citations

Unraveling the Golgi ribbon

Wei, J. H. & Seemann, J., Nov 1 2010, In : Traffic. 11, 11, p. 1391-1400 10 p.

Research output: Contribution to journalReview article

61 Scopus citations
2009

Induction of asymmetrical cell division to analyze spindle-dependent organelle partitioning using correlative microscopy techniques

Wei, J. H. & Seemann, J., Nov 2009, In : Nature Protocols. 4, 11, p. 1653-1663 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mitotic division of the mammalian Golgi apparatus

Wei, J. H. & Seemann, J., Sep 2009, In : Seminars in Cell and Developmental Biology. 20, 7, p. 810-816 7 p.

Research output: Contribution to journalReview article

44 Scopus citations

Remodeling of the Golgi structure by ERK signaling

Wei, J. H. & Seemann, J., Jan 1 2009, In : Communicative and Integrative Biology. 2, 1, p. 35-36 2 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Spindle-dependent partitioning of the Golgi ribbon

Wei, J. H. & Seemann, J., Dec 1 2009, In : Communicative and Integrative Biology. 2, 5, p. 406-407 2 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Targeting sequences of UBXD8 and AAM-B reveal that the ER has a direct role in the emergence and regression of lipid droplets

Zehmer, J. K., Bartz, R., Bisel, B., Liu, P., Seemann, J. & Anderson, R. G. W., Oct 15 2009, In : Journal of cell science. 122, 20, p. 3694-3702 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

The mitotic spindle mediates inheritance of the Golgi ribbon structure

Wei, J. H. & Seemann, J., Feb 9 2009, In : Journal of Cell Biology. 184, 3, p. 391-397 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Vesicular stomatitis virus inhibits mitotic progression and triggers cell death

Chakraborty, P., Seemann, J., Mishra, R. K., Wei, J. H., Weil, L., Nussenzveig, D. R., Heiber, J., Barber, G. N., Dasso, M. & Fontoura, B. M. A., Sep 14 2009, In : EMBO Reports. 10, 10, p. 1154-1160 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Viorio VopQ induces Pu-kmase-independent autophagy and antagonizes phagocytosis

Burdette, D. L., Seemann, J. & Orth, K., Aug 1 2009, In : Molecular Microbiology. 73, 4, p. 639-649 11 p.

Research output: Contribution to journalArticle

63 Scopus citations
2008

Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices

Miron-Mendoza, M., Seemann, J. & Grinnell, F., May 1 2008, In : Molecular biology of the cell. 19, 5, p. 2051-2058 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65

Bisel, B., Wang, Y., Wei, J. H., Xiang, Y., Tang, D., Miron-Mendoza, M., Yoshimura, S. I., Nakamura, N. & Seemann, J., Sep 8 2008, In : Journal of Cell Biology. 182, 5, p. 837-843 7 p.

Research output: Contribution to journalArticle

120 Scopus citations

Golgi cisternal unstacking stimulates COPI vesicle budding and protein transport

Wang, Y., Wei, J. H., Bisel, B., Tang, D. & Seemann, J., Feb 20 2008, In : PloS one. 3, 2, e1647.

Research output: Contribution to journalArticle

51 Scopus citations

Mitotic regulation of SREBP and ATF6 by separation of the Golgi and ER

Bartz, R. & Seemann, J., Jul 15 2008, In : Cell Cycle. 7, 14, p. 2100-2105 6 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Nucleoporin Levels Regulate Cell Cycle Progression and Phase-Specific Gene Expression

Chakraborty, P., Wang, Y., Wei, J. H., van Deursen, J., Yu, H., Malureanu, L., Dasso, M., Forbes, D. J., Levy, D. E., Seemann, J. & Fontoura, B. M. A., Nov 11 2008, In : Developmental Cell. 15, 5, p. 657-667 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Spatial separation of Golgi and ER during mitosis protects SREBP from unregulated activation

Bartz, R., Sun, L. P., Bisel, B., Wei, J. H. & Seemann, J., Apr 9 2008, In : EMBO Journal. 27, 7, p. 948-955 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2007

Active ADP-ribosylation factor-1 (ARF1) is required for mitotic Golgi fragmentation

Xiang, Y., Seemann, J., Bisel, B., Punthambaker, S. & Wang, Y., Jul 27 2007, In : Journal of Biological Chemistry. 282, 30, p. 21829-21837 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Evidence that mono-ADP-ribosylation of CtBP1/BARS regulates lipid storage

Bartz, R., Seemann, J., Zehmer, J. K., Serrero, G., Chapman, K. D., Anderson, R. G. W. & Liu, P., Aug 1 2007, In : Molecular biology of the cell. 18, 8, p. 3015-3025 11 p.

Research output: Contribution to journalArticle

23 Scopus citations
186 Scopus citations
2003

A direct role for GRASP65 as a mitotically regulated Golgi stacking factor

Wang, Y., Seemann, J., Pypaert, M., Shorter, J. & Warren, G., Jul 1 2003, In : EMBO Journal. 22, 13, p. 3279-3290 12 p.

Research output: Contribution to journalArticle

130 Scopus citations

Erratum: A direct role for GRASP65 as a mitotically regulated golgi stacking factor (EMBO Journal (22) (3279-3290))

Wang, Y., Seemann, J., Pypaert, M., Shorter, J. & Warren, G., Aug 1 2003, In : EMBO Journal. 22, 15, 1 p.

Research output: Contribution to journalComment/debate

2002

Partitioning of the matrix fraction of the golgi apparatus during mitosis in animal cells

Seemann, J., Pypaert, M., Taguchi, T., Malsam, J. & Warren, G., Feb 1 2002, In : Science. 295, 5556, p. 848-851 4 p.

Research output: Contribution to journalArticle

107 Scopus citations

Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115

Shorter, J., Beard, M. B., Seemann, J., Barbara Dirac-Svejstrup, A. & Warren, G., Apr 1 2002, In : Journal of Cell Biology. 157, 1, p. 45-62 18 p.

Research output: Contribution to journalArticle

155 Scopus citations
2000

A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

Meyer, H. H., Shorter, J. G., Seemann, J., Pappin, D. & Warren, G., May 15 2000, In : EMBO Journal. 19, 10, p. 2181-2192 12 p.

Research output: Contribution to journalArticle

364 Scopus citations

Matrix proteins can generate the higher order architecture of the Golgi apparatus

Seemann, J., Jokitalo, E., Pypaert, M. & Warren, G., Oct 26 2000, In : Nature. 407, 6807, p. 1022-1026 5 p.

Research output: Contribution to journalArticle

207 Scopus citations

Structural basis of the Ca2+-dependent association between S100C (S100A11) and its target, the N-terminal part of annexin I

Réty, S., Osterloh, D., Arié, J. P., Tabaries, S., Seeman, J., Russo-Marie, F., Gerke, V. & Lewit-Bentley, A., Feb 1 2000, In : Structure. 8, 2, p. 175-184 10 p.

Research output: Contribution to journalArticle

144 Scopus citations

The amino-terminal domain of the golgi protein Giantin interacts directly with the vesicle-tethering protein p115

Lesa, G. M., Seemann, J., Shortert, J., Vandekerckhove, J. & Warren, G., Jan 28 2000, In : Journal of Biological Chemistry. 275, 4, p. 2831-2836 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo

Seemann, J., Jokitalo, E. J. & Warren, G., Feb 2000, In : Molecular biology of the cell. 11, 2, p. 635-645 11 p.

Research output: Contribution to journalArticle

146 Scopus citations
1997

Annexin i targets S100C to early endosomes

Seemann, J., Weber, K. & Gerke, V., Aug 11 1997, In : FEBS Letters. 413, 1, p. 185-190 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Identification and characterization of a novel type of annexin-membrane interaction: Ca2+ is not required for the association of annexin II with early endosomes

Jost, M., Zeuschner, D., Seemann, J., Weber, K. & Gerke, V., Jan 1 1997, In : Journal of cell science. 110, 2, p. 221-228 8 p.

Research output: Contribution to journalArticle

93 Scopus citations
1996

Structural requirements for annexin I-S100C complex-formation

Seemann, J., Weber, K. & Gerke, V., Jan 1 1996, In : Biochemical Journal. 319, 1, p. 123-129 7 p.

Research output: Contribution to journalArticle

69 Scopus citations