Cell Biology - Division F

Research output

Research output per year 1990 2006 2007 2008 2012 2013 2014 2016 2018 2019 2020 2023 2023

• 50 Article
• 5 Review article
• 2 Comment/debate
• 2 Editorial
• 3 More
  • 2 Short survey
  • 1 Letter

Research output per year

Research output per year

Search results

• 2023

  Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

  Kehrer, T., Cupic, A., Ye, C., Yildiz, S., Bouhaddou, M., Crossland, N. A., Barrall, E. A., Cohen, P., Tseng, A., Cagatay, T., Rathnasinghe, R., Flores, D., Jangra, S., Alam, F., Mena, I., Aslam, S., Saqi, A., Rutkowska, M., Ummadi, M. R., Pisanelli, G., & 20 othersRichardson, R. B., Veit, E. C., Fabius, J. M., Soucheray, M., Polacco, B. J., Ak, B., Marin, A., Evans, M. J., Swaney, D. L., Gonzalez-Reiche, A. S., Sordillo, E. M., van Bakel, H., Simon, V., Zuliani-Alvarez, L., Fontoura, B. M. A., Rosenberg, B. R., Krogan, N. J., Martinez-Sobrido, L., García-Sastre, A. & Miorin, L., Oct 11 2023, In: Cell Host and Microbe. 31, 10, p. 1668-1684.e12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus 100%
  • Severe Acute Respiratory Syndrome 74%
  • Coronavirus 72%
  • interferons 65%
  • immune evasion 57%
  8 Scopus citations

• Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex

  Bhat, P., Aksenova, V., Gazzara, M., Rex, E. A., Aslam, S., Haddad, C., Gao, S., Esparza, M., Cagatay, T., Batten, K., El Zahed, S. S., Arnaoutov, A., Zhong, H., Shay, J. W., Tolbert, B. S., Dasso, M., Lynch, K. W., García-Sastre, A. & Fontoura, B. M. A., Dec 2023, In: Nature communications. 14, 1, 2304.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • influenza 100%
  • viruses 77%
  • Cell Nucleus Active Transport 77%
  • determinants 69%
  • Orthomyxoviridae 66%
  1 Scopus citations

• Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly

  Xie, Y., Gao, S., Zhang, K., Bhat, P., Clarke, B. P., Batten, K., Mei, M., Gazzara, M., Shay, J. W., Lynch, K. W., Angelos, A. E., Hill, P. S., Ivey, A. L., Fontoura, B. & Ren, Y., Aug 29 2023, In: Cell Reports. 42, 8, 112988.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • messenger ribonucleoprotein 100%
  • RNA Sequencing 35%
  • RNA 33%
  • Messenger RNA 27%
  • Ribonucleoproteins 20%
  2 Scopus citations
• 2022

  Nuclear speckle integrity and function require TAO2 kinase

  Gao, S., Esparza, M., Dehghan, I., Aksenova, V., Zhang, K., Batten, K., Ferretti, M. B., Begg, B. E., Cagatay, T., Shay, J. W., Garcıa-Sastre, A., Goldsmith, E. J., Chen, Z. J., Dasso, M., Lynch, K. W., Cobb, M. H. & Fontoura, B. M. A., Jun 21 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 25, e2206046119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphotransferases 100%
  • Messenger RNA 73%
  • RNA Splicing 69%
  • Cell Nucleus Active Transport 60%
  • Viral Proteins 54%
  2 Scopus citations

• Viral–host interactions during splicing and nuclear export of influenza virus mRNAs

  Esparza, M., Bhat, P. & Fontoura, B. MA., Aug 2022, In: Current Opinion in Virology. 55, 101254.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cell Nucleus Active Transport 100%
  • Orthomyxoviridae 85%
  • Influenza A virus 69%
  • Messenger RNA 48%
  • RNA Splicing 28%
  8 Scopus citations
• 2021

  Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein

  White, K., Esparza, M., Liang, J., Bhat, P., Naidoo, J., McGovern, B. L., Williams, M. A. P., Alabi, B. R., Shay, J., Niederstrasser, H., Posner, B., García-Sastre, A., Ready, J. & Fontoura, B. M. A., Aug 12 2021, In: Journal of Medicinal Chemistry. 64, 15, p. 10951-10966 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sulfonamides 100%
  • Hemagglutinins 89%
  • Sulfonamide 81%
  • Orthomyxoviridae 81%
  • Antiviral Agents 68%
  7 Scopus citations

• Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression

  Zhang, K., Miorin, L., Makio, T., Dehghan, I., Gao, S., Xie, Y., Zhong, H., Esparza, M., Kehrer, T., Kumar, A., Hobman, T. C., Ptak, C., Gao, B., Minna, J. D., Chen, Z., García-Sastre, A., Ren, Y., Wozniak, R. W. & Fontoura, B. M. A., Feb 5 2021, In: Science Advances. 7, 6, eabe7386.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS coronavirus Nsp1 protein 100%
  • Gene Expression 24%
  • Messenger RNA 23%
  • SARS Virus 20%
  • Nuclear Pore 9%
  127 Scopus citations
• 2020

  Chemical intervention of influenza virus mRNA nuclear export

  Esparza, M., Mor, A., Niederstrasser, H., White, K., White, A., Zhang, K., Gao, S., Wang, J., Liang, J., Sho, S., Sakthivel, R., Sathe, A. A., Xing, C., Muñoz-Moreno, R., Shay, J. W., García-Sastre, A., Ready, J., Posner, B. & Fontoura, B. M. A., Apr 1 2020, In: PLoS pathogens. 16, 4, e1008407.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Orthomyxoviridae 100%
  • Cell Nucleus Active Transport 99%
  • RNA transport 96%
  • Influenza A virus 56%
  • Messenger RNA 48%
  11 Scopus citations

• Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway

  Aksenova, V., Smith, A., Lee, H., Bhat, P., Esnault, C., Chen, S., Iben, J., Kaufhold, R., Yau, K. C., Echeverria, C., Fontoura, B., Arnaoutov, A. & Dasso, M., Dec 1 2020, In: Nature communications. 11, 1, 4577.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nuclear Pore Complex Proteins 100%
  • Nuclear Pore 90%
  • Pore 44%
  • Messenger RNA 38%
  • Indoleacetic Acids 37%
  56 Scopus citations

• SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

  Miorin, L., Kehrer, T., Sanchez-Aparicio, M. T., Zhang, K., Cohen, P., Patel, R. S., Cupic, A., Makio, T., Mei, M., Moreno, E., Danziger, O., White, K. M., Rathnasinghe, R., Uccellini, M., Gao, S., Aydillo, T., Mena, I., Yin, X., Martin-Sancho, L., Krogan, N. J., & 7 othersChanda, S. K., Schotsaert, M., Wozniak, R. W., Ren, Y., Rosenberg, B. R., Fontoura, B. M. A. & García-Sastre, A., Nov 10 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 45, p. 28344-28354 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Cell Nucleus Active Transport 91%
  • Interferons 71%
  • Karyopherins 55%
  327 Scopus citations

• Viral-induced alternative splicing of host genes promotes influenza replication

  Thompson, M. G., Dittmar, M., Mallory, M. J., Bhat, P., Ferretti, M. B., Fontoura, B. M., Cherry, S. & Lynch, K. W., Dec 2020, In: eLife. 9, p. 1-20 20 p., e55500.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Influenza A virus 100%
  • Alternative Splicing 98%
  • Human Influenza 83%
  • Heterogeneous-Nuclear Ribonucleoprotein K 64%
  • Virus Diseases 38%
  32 Scopus citations
• 2019

  DEAD-box ATPases are global regulators of phase-separated organelles

  Hondele, M., Sachdev, R., Heinrich, S., Wang, J., Vallotton, P., Fontoura, B. M. A. & Weis, K., Sep 5 2019, In: Nature. 573, 7772, p. 144-148 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Dichlorodiphenyl Dichloroethylene 100%
  • Adenosine Triphosphatases 85%
  • Organelles 81%
  • RNA 59%
  • Adenosine Triphosphate 26%
  216 Scopus citations

• Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination

  Liu, Z., Yan, M., Liang, Y., Liu, M., Zhang, K., Shao, D., Jiang, R., Li, L., Wang, C., Nussenzveig, D. R., Zhang, K., Chen, S., Zhong, C., Mo, W., Fontoura, B. M. A. & Zhang, L., May 8 2019, In: Neuron. 102, 3, p. 587-601.e7

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nuclear Pore Complex Proteins 100%
  • Oligodendroglia 74%
  • Oligodendrocyte Precursor Cells 35%
  • Remyelination 35%
  • Myelin Sheath 13%
  56 Scopus citations

• Structural basis for influenza virus NS1 protein block of mRNA nuclear export

  Zhang, K., Xie, Y., Muñoz-Moreno, R., Wang, J., Zhang, L., Esparza, M., García-Sastre, A., Fontoura, B. M. A. & Ren, Y., Oct 1 2019, In: Nature microbiology. 4, 10, p. 1671-1679 9 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Viral Structural Proteins 100%
  • Cell Nucleus Active Transport 85%
  • Orthomyxoviridae 73%
  • Messenger RNA 41%
  • Proteins 26%
  36 Scopus citations
• 2018

  Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing

  Thompson, M. G., Muñoz-Moreno, R., Bhat, P., Roytenberg, R., Lindberg, J., Gazzara, M. R., Mallory, M. J., Zhang, K., García-Sastre, A., Fontoura, B. M. A. & Lynch, K. W., Dec 1 2018, In: Nature communications. 9, 1, 2407.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heterogeneous-Nuclear Ribonucleoprotein K 100%
  • influenza 91%
  • splicing 76%
  • Human Influenza 55%
  • viruses 47%
  52 Scopus citations

• Editorial overview: The cell nucleus: Dynamic interplay of shape and function

  Dasso, M. & Fontoura, B. M. A., Jun 2018, In: Current Opinion in Cell Biology. 52, p. iv-vi

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Günter Blobel 1936-2018

  Chook, Y. M., Fontoura, B. M. A. & Rout, M. P., Apr 1 2018, In: Nature structural & molecular biology. 25, 4, p. 297-298 2 p.

  Research output: Contribution to journal › Article › peer-review

• Influenza virus NS1 protein-RNA interactome reveals intron targeting

  Zhang, L., Wang, J., Muñoz-Moreno, R., Kim, M., Sakthivel, R., Mo, W., Shao, D., Anantharaman, A., García-Sastre, A., Conrad, N. K. & Fontoura, B. M., Dec 1 2018, In: Journal of virology. 92, 24, e0163418.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • influenza virus INS1 protein 100%
  • Orthomyxoviridae 67%
  • RNA Precursors 56%
  • Introns 54%
  • introns 49%
  19 Scopus citations

• Structural–functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression

  Zhang, K., Shang, G., Padavannil, A., Wang, J., Sakthivel, R., Chen, X., Kim, M., Thompson, M. G., García-Sastre, A., Lynch, K. W., Chen, Z., Chook, Y. M. & Fontoura, B. M., Dec 26 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. E12218-E12227

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein Splicing 100%
  • Viral Genes 79%
  • Gene Expression 40%
  • Cell Nucleus Active Transport 40%
  • Messenger RNA 38%
  20 Scopus citations
• 2017

  Corrigendum: Influenza virus mRNA trafficking through host nuclear speckles

  Mor, A., White, A., Zhang, K., Thompson, M., Esparza, M., Muñoz-Moreno, R., Koide, K., Lynch, K. W., García-Sastre, A. & Fontoura, B. M. A., Jan 9 2017, In: Nature microbiology. 2, p. 17002 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  1 Scopus citations

• Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication

  Kuss-Duerkop, S. K., Wang, J., Mena, I., White, K., Metreveli, G., Sakthivel, R., Mata, M. A., Muñoz-Moreno, R., Chen, X., Krammer, F., Diamond, M. S., Chen, Z. J., García-Sastre, A. & Fontoura, B. M. A., Sep 2017, In: PLoS pathogens. 13, 9, e1006635.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanistic Target of Rapamycin Complex 2 100%
  • Mechanistic Target of Rapamycin Complex 1 87%
  • Orthomyxoviridae 82%
  • viral proteins 39%
  • infection 30%
  70 Scopus citations
• 2016

  Gating Immunity and Death at the Nuclear Pore Complex

  Dasso, M. & Fontoura, B. M. A., Sep 8 2016, In: Cell. 166, 6, p. 1364-1366 3 p.

  Research output: Contribution to journal › Short survey › peer-review

  Open Access

  • Nuclear Pore 100%
  • Cell Nucleus Active Transport 87%
  • Immunity 60%
  • Cyclin Dependent Kinase Inhibitor 60%
  • Pore 48%
  1 Scopus citations

• Influenza virus mRNA trafficking through host nuclear speckles

  Mor, A., White, A., Zhang, K., Thompson, M., Esparza, M., Muñoz-Moreno, R., Koide, K., Lynch, K. W., García-Sastre, A. & Fontoura, B. M. A., May 27 2016, In: Nature microbiology. 1, 7, 16069.

  Research output: Contribution to journal › Article › peer-review

  • Orthomyxoviridae 100%
  • Messenger RNA 56%
  • RNA Splicing Factors 26%
  • Cell Nucleus Active Transport 23%
  • Viral Genes 23%
  67 Scopus citations

• UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

  Zhang, M., Mishra, S., Sakthivel, R., Fontoura, B. M. A. & Nussenzweig, V., 2016, In: PLoS pathogens. 12, 1, e1005370.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sporozoites 100%
  • Eukaryotic Initiation Factor-2 97%
  • sporozoites 92%
  • Plasmodium 89%
  • Phosphoric Monoester Hydrolases 76%
  29 Scopus citations
• 2015

  Sec13 Regulates Expression of Specific Immune Factors Involved in Inflammation In Vivo

  Moreira, T. G., Zhang, L., Shaulov, L., Harel, A., Kuss, S. K., Williams, J., Shelton, J., Somatilaka, B., Seemann, J., Yang, J., Sakthivel, R., Nussenzveig, D. R., Faria, A. M. C. & Fontoura, B. M. A., Dec 3 2015, In: Scientific reports. 5, 17655.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunologic Factors 100%
  • Inflammation 54%
  • COP-Coated Vesicles 27%
  • Nuclear Pore 20%
  • T-Lymphocytes 19%
  19 Scopus citations
• 2014

  Nuclear trafficking in health and disease

  Mor, A., White, M. A. & Fontoura, B. M. A., Jun 2014, In: Current Opinion in Cell Biology. 28, 1, p. 28-35 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Nuclear Pore 100%
  • Cell Nucleus Active Transport 87%
  • Cytoplasm 61%
  • Nuclear Pore Complex Proteins 55%
  • Nuclear Envelope 42%
  61 Scopus citations

• Primate-specific miR-576-3p sets host defense signalling threshold

  Yarbrough, M. L., Zhang, K., Sakthivel, R., Forst, C. V., Posner, B. A., Barber, G. N., White, M. A. & Fontoura, B. M. A., 2014, In: Nature communications. 5, 4963.

  Research output: Contribution to journal › Article › peer-review

  • interferon 100%
  • primates 83%
  • infectious diseases 72%
  • MicroRNA 70%
  • viruses 68%
  50 Scopus citations

• Viral Subversion of Nucleocytoplasmic Trafficking

  Yarbrough, M. L., Mata, M. A., Sakthivel, R. & Fontoura, B. M. A., Feb 2014, In: Traffic. 15, 2, p. 127-140 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Nucleus Active Transport 100%
  • Viruses 68%
  • Nuclear Pore 45%
  • Pore 44%
  • Protein 42%
  94 Scopus citations
• 2013

  Cellular RNA Binding Proteins NS1-BP and hnRNP K Regulate Influenza A Virus RNA Splicing

  Tsai, P. L., Chiou, N. T., Kuss, S., García-Sastre, A., Lynch, K. W. & Fontoura, B. M. A., Jun 2013, In: PLoS pathogens. 9, 6, e1003460.

  Research output: Contribution to journal › Article › peer-review

  • Heterogeneous-Nuclear Ribonucleoprotein K 100%
  • protein K 99%
  • RNA splicing 88%
  • RNA Splicing 80%
  • RNA-binding proteins 76%
  73 Scopus citations

• Nuclear imprisonment: Viral strategies to arrest host mRNA nuclear export

  Kuss, S. K., Mata, M. A., Zhang, L. & Fontoura, B. M. A., Jul 18 2013, In: Viruses. 5, 7, p. 1824-1849 26 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Nucleus Active Transport 100%
  • Messenger RNA 48%
  • Viruses 45%
  • Antiviral Agents 43%
  • Nuclear Pore Complex Proteins 25%
  54 Scopus citations

• SAR-based optimization of a 4-quinoline carboxylic acid analogue with potent antiviral activity

  Das, P., Deng, X., Zhang, L., Roth, M. G., Fontoura, B. M. A., Phillips, M. A. & De Brabander, J. K., Jun 13 2013, In: ACS Medicinal Chemistry Letters. 4, 6, p. 517-521 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • quinoline-4-carboxylic acid 100%
  • Quinoline-4-Carboxylic Acid 84%
  • dihydroorotate dehydrogenase 81%
  • Dihydroorotate 77%
  • Drug Delivery Systems 47%
  53 Scopus citations
• 2012

  Host modulators of H1N1 cytopathogenicity

  Ward, S. E., Kim, H. S., Komurov, K., Mendiratta, S., Tsai, P. L., Schmolke, M., Satterly, N., Manicassamy, B., Forst, C. V., Roth, M. G., García-Sastre, A., Blazewska, K. M., McKenna, C. E., Fontoura, B. M. & White, M. A., Aug 2 2012, In: PloS one. 7, 8, e39284.

  Research output: Contribution to journal › Article › peer-review

  • cytopathogenicity 100%
  • viral proteins 91%
  • Viral Proteins 84%
  • epithelial cells 69%
  • Influenza A virus 58%
  30 Scopus citations

• Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

  Zhang, L., Das, P., Schmolke, M., Manicassamy, B., Wang, Y., Deng, X., Cai, L., Tu, B. P., Forst, C. V., Roth, M. G., Levy, D. E., García-Sastre, A., de Brabander, J., Phillips, M. A. & Fontoura, B. M. A., Feb 6 2012, In: Journal of Cell Biology. 196, 3, p. 315-326 12 p.

  Research output: Contribution to journal › Article › peer-review

  • pyrimidine 100%
  • Cell Nucleus Active Transport 95%
  • Virulence Factors 84%
  • RNA 56%
  • dihydroorotate dehydrogenase 39%
  50 Scopus citations

• Shaping the p53 Response with Nucleoporins

  Yarbrough, M. L., White, M. A. & Fontoura, B. M. A., Dec 14 2012, In: Molecular cell. 48, 5, p. 665-666 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • nuclear pore complex protein 98 100%
  • Nuclear Pore Complex Proteins 85%
  • Exosomes 68%
  • DNA Damage 50%
  • Messenger RNA 33%
  4 Scopus citations
• 2011

  Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

  Mata, M. A., Satterly, N., Versteeg, G. A., Frantz, D., Wei, S., Williams, N., Schmolke, M., Peña-Llopis, S., Brugarolas, J., Forst, C. V., White, M. A., García-Sastre, A., Roth, M. G. & Fontoura, B. M. A., Oct 2011, In: Nature chemical biology. 7, 10, p. 712-719 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1 100%
  • Naphthalimides 98%
  • RNA Viruses 90%
  • TOR Serine-Threonine Kinases 88%
  • Viral Proteins 56%
  70 Scopus citations

• Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1

  Zhang, Z. C., Satterly, N., Fontoura, B. M. A. & Chook, Y. M., Dec 1 2011, In: Molecular biology of the cell. 22, 23, p. 4657-4668 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Karyopherins 100%
  • Nuclear Localization Signals 89%
  • Messenger RNA 39%
  • Cell Nucleus Active Transport 14%
  • Proline 13%
  22 Scopus citations
• 2010

  The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores

  Mishra, R. K., Chakraborty, P., Arnaoutov, A., Fontoura, B. M. A. & Dasso, M., Feb 2010, In: Nature cell biology. 12, 2, p. 164-169 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Kinetochores 100%
  • Polymerization 78%
  • Microtubules 74%
  • Tubulin 14%
  • Guanosine Triphosphate 14%
  152 Scopus citations

• The Plasmodium eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

  Zhang, M., Fennell, C., Ranford-Cartwright, L., Sakthivel, R., Gueirard, P., Meister, S., Caspi, A., Doerig, C., Nussenzweig, R. S., Tuteja, R., Sullivan, W. J., Roos, D. S., Fontoura, B. M. A., Ménard, R., Winzeler, E. A. & Nussenzweig, V., Jul 5 2010, In: Journal of Experimental Medicine. 207, 7, p. 1465-1474 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Eukaryotic Initiation Factor-2 100%
  • Sporozoites 88%
  • Plasmodium 78%
  • Culicidae 70%
  • Salivary Glands 68%
  103 Scopus citations
• 2009

  Vesicular stomatitis virus inhibits mitotic progression and triggers cell death

  Chakraborty, P., Seemann, J., Mishra, R. K., Wei, J. H., Weil, L., Nussenzveig, D. R., Heiber, J., Barber, G. N., Dasso, M. & Fontoura, B. M. A., 2009, In: EMBO Reports. 10, 10, p. 1154-1160 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vesicular Stomatitis 100%
  • Cell Death 83%
  • Oncolytic 68%
  • Viruses 52%
  • Ribonucleoproteins 27%
  25 Scopus citations
• 2008

  NFAR-1 and -2 modulate translation and are required for efficient host defense

  Pfeifer, I., Elsby, R., Fernandez, M., Faria, P. A., Nussenzveig, D. R., Lossos, I. S., Fontoura, B. M. A., Martin, W. D. & Barber, G. N., Mar 18 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 11, p. 4173-4178 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Messenger RNA 100%
  • Vesicular Stomatitis 74%
  • Ribonucleoproteins 72%
  • Double-Stranded RNA 70%
  • Virus Replication 58%
  59 Scopus citations

• Nucleoporin Levels Regulate Cell Cycle Progression and Phase-Specific Gene Expression

  Chakraborty, P., Wang, Y., Wei, J. H., van Deursen, J., Yu, H., Malureanu, L., Dasso, M., Forbes, D. J., Levy, D. E., Seemann, J. & Fontoura, B. M. A., Nov 11 2008, In: Developmental cell. 15, 5, p. 657-667 11 p.

  Research output: Contribution to journal › Article › peer-review

  • nuclear pore complex protein 96 100%
  • Nuclear Pore Complex Proteins 68%
  • Cell Cycle 36%
  • Pore 30%
  • Gene Expression 27%
  76 Scopus citations

• Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite (DOI:10.1016/j.cell.2007.09.013)

  Singh, A. P., Buscaglia, C. A., Wang, Q., Levay, A., Nussenzweig, D. R., Walker, J. R., Winzeler, E. A., Fujii, H., Fontoura, B. M. A. & Nussenzweig, V., Apr 18 2008, In: Cell. 133, 2, p. 375 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
• 2007

  Influenza virus targets the mRNA export machinery and the nuclear pore complex

  Satterly, N., Tsai, P. L., Van Deursen, J., Nussenzveig, D. R., Wang, Y., Faria, P. A., Levay, A., Levy, D. E. & Fontoura, B. M. A., Feb 6 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 6, p. 1853-1858 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nuclear Pore 100%
  • Orthomyxoviridae 75%
  • Messenger RNA 42%
  • Virus Replication 21%
  • Human Influenza 19%
  243 Scopus citations

• Plasmodium Circumsporozoite Protein Promotes the Development of the Liver Stages of the Parasite

  Singh, A. P., Buscaglia, C. A., Wang, Q., Levay, A., Nussenzweig, D. R., Walker, J. R., Winzeler, E. A., Fujii, H., Fontoura, B. M. A. & Nussenzweig, V., Nov 2 2007, In: Cell. 131, 3, p. 492-504 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Protozoan circumsporozoite protein 100%
  • Parasites 50%
  • Metabolic 49%
  • Hepatocytes 38%
  • Plasmodium 36%
  172 Scopus citations

• Structure-based design of a pathway-specific nuclear import inhibitor

  Cansizoglu, A. E., Lee, B. J., Zhang, Z. C., Fontoura, B. M. A. & Chook, Y. M., May 2007, In: Nature Structural and Molecular Biology. 14, 5, p. 452-454 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear Localization Signals 100%
  • Cell Nucleus Active Transport 91%
  • Karyopherins 55%
  • Ligands 27%
  135 Scopus citations
• 2006

  Nuclear export assays for poly(A) RNAs

  Chakraborty, P., Satterly, N. & Fontoura, B. M. A., Aug 2006, In: Methods. 39, 4, p. 363-369 7 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA (Poly(A)) 100%
  • Cell Nucleus Active Transport 79%
  • Messenger RNA 38%
  • oligo (dT) 31%
  • In Situ Hybridization 17%
  21 Scopus citations

• Studying nucleocytoplasmic transport

  Fontoura, B. M. A., Aug 2006, In: Methods. 39, 4, p. 275-276 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions

  Faria, A. M. C., Levay, A., Wang, Y., Kamphorst, A. O., Rosa, M. L. P., Nussenzveig, D. R., Balkan, W., Chook, Y. M., Levy, D. E. & Fontoura, B. M. A., Mar 2006, In: Immunity. 24, 3, p. 295-304 10 p.

  Research output: Contribution to journal › Article › peer-review

  • nuclear pore complex protein 96 100%
  • Interferons 42%
  • Proteins 17%
  • T-Lymphocytes 5%
  • Cell Nucleus Active Transport 5%
  83 Scopus citations

• The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly

  Orjalo, A. V., Arnaoutov, A., Shen, Z., Boyarchuk, Y., Zeitlin, S. G., Fontoura, B., Briggs, S., Dasso, M. & Forbes, D. J., Sep 2006, In: Molecular biology of the cell. 17, 9, p. 3806-3818 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nuclear Pore Complex Proteins 100%
  • Kinetochores 88%
  • Prometaphase 33%
  • Microtubules 32%
  • Nuclear Pore 30%
  125 Scopus citations
• 2005

  Viral interactions with the nuclear transport machinery: Discovering and disrupting pathways

  Fontoura, B. M. A., Faria, P. A. & Nussenzveig, D. R., Feb 2005, In: IUBMB life. 57, 2, p. 65-72 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Nucleus Active Transport 100%
  • Vesicular stomatitis virus M protein 65%
  • Viruses 45%
  • Messenger RNA 38%
  • Nuclear Proteins 35%
  49 Scopus citations