Cell Biology - Division L

Research Output

2020

Biomedical ethics 2.0: redefining the meaning of disease, patient and treatment

Grinnell, F., Aug 1 2020, In : Nature Reviews Molecular Cell Biology. 21, 8, p. 417-418 2 p.

Research output: Contribution to journalComment/debate

High school science fair: Positive and negative outcomes

Grinnell, F., Dalley, S. & Reisch, J., 2020, In : PloS one. 15, 2, e0229237.

Research output: Contribution to journalArticle

Open Access
2019

Abduction in the everyday practice of science: the logic of unintended experiments

Grinnell, F., Jun 1 2019, In : Transactions of the Charles S Peirce Society. 55, 3, p. 215-227 13 p.

Research output: Contribution to journalArticle

The scientific attitude

Grinnell, F., Jul 9 2019, Taylor and Francis. 141 p.

Research output: Book/ReportBook

1 Scopus citations
2018

High school science fair: Student opinions regarding whether participation should be required or optional and why

Grinnell, F., Dalley, S., Shepherd, K. & Reisch, J., Aug 1 2018, In : PLoS One. 13, 8, e0202320.

Research output: Contribution to journalArticle

4 Scopus citations

Research integrity and everyday practice of science

Grinnell, F. L., Jul 23 2018, Getting to Good: Research Integrity in the Biomedical Sciences. Springer International Publishing, p. 23-40 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017
2 Scopus citations

Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices

Ozcelikkale, A., Dutton, J. C., Grinnell, F. & Han, B., Oct 1 2017, In : Journal of the Royal Society Interface. 14, 135, 20170287.

Research output: Contribution to journalArticle

4 Scopus citations

High school science fair and research integrity

Grinnell, F., Dalley, S., Shepherd, K. & Reisch, J., Mar 1 2017, In : PLoS One. 12, 3, e0174252.

Research output: Contribution to journalArticle

4 Scopus citations
4 Scopus citations
2015

PDGF-stimulated dispersal of cell clusters and disruption of fibronectin matrix on three-dimensional collagen matrices requires matrix metalloproteinase-2

Da Rocha-Azevedo, B., Ho, C. H. & Grinnell, F., Mar 15 2015, In : Molecular biology of the cell. 26, 6, p. 1098-1105 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Preservation of tissue microstructure and functionality during freezing by modulation of cytoskeletal structure

Park, S., Seawright, A., Park, S., Dutton, J. C., Grinnell, F. & Han, B., May 1 2015, In : Journal of the Mechanical Behavior of Biomedical Materials. 45, p. 32-44 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Rethink our approach to assessing risk

Grinnell, F., Jun 17 2015, In : Nature. 522, 7556, p. 257 1 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

The different roles of myosin IIA and myosin IIB in contraction of 3D collagen matrices by human fibroblasts

Liu, Z., Ho, C. H. & Grinnell, F., Aug 15 2014, In : Experimental Cell Research. 326, 2, p. 295-306 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing

Velasquez, L. S., Sutherland, L. B., Liu, Z., Grinnell, F., Kamm, K. E., Schneider, J. W., Olson, E. N. & Small, E. M., Oct 15 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 16850-16855 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Fibroblast cluster formation on 3D collagen matrices requires cell contraction dependent fibronectin matrix organization

da Rocha-Azevedo, B., Ho, C. H. & Grinnell, F., Feb 15 2013, In : Experimental Cell Research. 319, 4, p. 546-555 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Fibroblast morphogenesis on 3D collagen matrices: The balance between cell clustering and cell migration

da Rocha-Azevedo, B. & Grinnell, F., Oct 1 2013, In : Experimental Cell Research. 319, 16, p. 2440-2446 7 p.

Research output: Contribution to journalReview article

26 Scopus citations

It is time to update US biomedical funding

Grinnell, F., Sep 19 2013, In : Nature. 501, 7466, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Research Integrity and Everyday Practice of Science

Grinnell, F., Sep 1 2013, In : Science and Engineering Ethics. 19, 3, p. 685-701 17 p.

Research output: Contribution to journalArticle

9 Scopus citations

The effect of growth factor environment on fibroblast morphological response to substrate stiffness

Grinnell, F. & Ho, C. H., Jan 1 2013, In : Biomaterials. 34, 4, p. 965-974 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Thermomechanical analysis of freezing-induced cell-fluid-matrix interactions in engineered tissues

Han, B., Teo, K. Y., Ghosh, S., Dutton, J. C. & Grinnell, F., Feb 1 2013, In : Journal of the Mechanical Behavior of Biomedical Materials. 18, p. 67-80 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Effects of freezing-induced cell-fluid-matrix interactions on cells and extracellular matrix of engineered tissues

Teo, K. Y., Dutton, J. C., Grinnell, F. & Han, B., Dec 1 2011, ASME 2011 Summer Bioengineering Conference, SBC 2011. PARTS A AND B ed. p. 133-134 2 p. (ASME 2011 Summer Bioengineering Conference, SBC 2011; no. PARTS A AND B).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Effects of freezing-induced cell-fluid-matrix interactions on the cells and extracellular matrix of engineered tissues

Teo, K. Y., DeHoyos, T. O., Dutton, J. C., Grinnell, F. & Han, B., Aug 1 2011, In : Biomaterials. 32, 23, p. 5380-5390 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

The evolution of credibility

Grinnell, F., Feb 1 2011, In : Scientist. 25, 2, 1 p.

Research output: Contribution to journalArticle

2010

Cell motility and mechanics in three-dimensional collagen matrices

Grinnell, F. & Petroll, W. M., Nov 10 2010, In : Annual Review of Cell and Developmental Biology. 26, p. 335-361 27 p.

Research output: Contribution to journalReview article

216 Scopus citations

Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis

Rhee, S., Ho, C. H. & Grinnell, F., Jan 15 2010, In : Experimental Cell Research. 316, 2, p. 232-244 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices

Miron-Mendoza, M., Seemann, J. & Grinnell, F., Sep 1 2010, In : Biomaterials. 31, 25, p. 6425-6435 11 p.

Research output: Contribution to journalArticle

148 Scopus citations
2009

Discovery in the lab: Plato's paradox and Delbrück's principle of limited sloppiness

Grinnell, F., Jan 1 2009, In : FASEB Journal. 23, 1, p. 7-9 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations
31 Scopus citations
2008

Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices

Miron-Mendoza, M., Seemann, J. & Grinnell, F., May 1 2008, In : Molecular biology of the cell. 19, 5, p. 2051-2058 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Distinguishing fibroblast promigratory and procontractile growth factor environments in 3-D collagen matrices

Jiang, H., Rhee, S., Ho, C. H. & Grinnell, F., Jul 1 2008, In : FASEB Journal. 22, 7, p. 2151-2160 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Fibroblast mechanics in three-dimensional collagen matrices

Grinnell, F., Jul 1 2008, In : Journal of Bodywork and Movement Therapies. 12, 3, p. 191-193 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices

Menezes, G. C., Miron-Mendoza, M., Ho, C. H., Jiang, H. & Grinnell, F., Oct 1 2008, In : Experimental Cell Research. 314, 16, p. 3081-3091 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
2007

Fibroblast mechanics in 3D collagen matrices

Rhee, S. & Grinnell, F., Nov 10 2007, In : Advanced Drug Delivery Reviews. 59, 13, p. 1299-1305 7 p.

Research output: Contribution to journalReview article

130 Scopus citations
106 Scopus citations
2006

Intelligent design: Fallacy recapitulates ontogeny

Grinnell, F., Mar 1 2006, In : FASEB Journal. 20, 3, p. 410-411 2 p.

Research output: Contribution to journalShort survey

Nested collagen matrices: A new model to study migration of human fibroblast populations in three dimensions

Grinnell, F., B. Rocha, L., Iucu, C., Rhee, S. & Jiang, H., Jan 1 2006, In : Experimental Cell Research. 312, 1, p. 86-94 9 p.

Research output: Contribution to journalArticle

83 Scopus citations

P21-activated kinase 1: Convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human broblasts

Rhee, S. & Grinnell, F., Jan 30 2006, In : Journal of Cell Biology. 172, 3, p. 423-432 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2005

Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices

Jiang, H. & Grinnell, F., Nov 1 2005, In : Molecular biology of the cell. 16, 11, p. 5070-5076 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Ethical decision making [3]

Grinnell, F., Aug 11 2005, In : Nature. 436, 7052, 1 p.

Research output: Contribution to journalLetter

Misconduct: acceptable practices differ by field.

Grinnell, F., Aug 11 2005, In : Nature. 436, 7052, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations
2004

Human embryo research: From moral uncertainty to death

Grinnell, F., Dec 2004, In : American Journal of Bioethics. 4, 1, p. 12-11 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Subject vulnerability: The precautionary principle of human research

Grinnell, F., Dec 1 2004, In : American Journal of Bioethics. 4, 3, p. 72-74 3 p.

Research output: Contribution to journalComment/debate

9 Scopus citations
2003

Defining embryo death would permit important research

Grinnell, F., May 16 2003, In : Chronicle of Higher Education. 49, 36 SEC.2, p. B13

Research output: Contribution to journalReview article

5 Scopus citations

Dendritic fibroblasts in three-dimensional collagen matrices

Grinnell, F., Ho, C. H., Tamariz, E., Lee, D. J. & Skuta, G., Feb 1 2003, In : Molecular biology of the cell. 14, 2, p. 384-395 12 p.

Research output: Contribution to journalArticle

160 Scopus citations
48 Scopus citations

Fibroblast biology in three-dimensional collagen matrices

Grinnell, F., May 1 2003, In : Trends in Cell Biology. 13, 5, p. 264-269 6 p.

Research output: Contribution to journalReview article

609 Scopus citations

Fibroblast quiescence in floating collagen matrices. Decrease in serum activation of MEK and Raf but not Ras

Fringer, J. & Grinnell, F., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 20612-20617 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
25 Scopus citations
2002

Bioethical pluralism and complementarity

Grinnell, F., Bishop, J. P. & McCullough, L. B., Jan 1 2002, In : Perspectives in biology and medicine. 45, 3, p. 338-349 12 p.

Research output: Contribution to journalReview article

6 Scopus citations