Cell Biology - Division M

Research output

Research output per year 1985 1989 1996 1998 1999 2000 2002 2003 2004 2007 2008 2009 2013 2014 2015 2018 2020 2023

• 62 Article
• 16 Review article
• 3 Chapter
• 2 Comment/debate
• 4 More
  • 1 Conference contribution
  • 1 Editorial
  • 1 Letter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2023

  Apoptotic cell death in disease—Current understanding of the NCCD 2023

  Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J., Bazan, N. G., & 208 othersBecker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Terminology 100%
  • Cell Death 75%
  • Apoptosis 60%
  • Regulated Cell Death 51%
  • Homeostasis 48%
  66 Scopus citations
• 2022

  Distinct p53 isoforms code for opposing transcriptional outcomes

  Wylie, A., Jones, A. E., Das, S., Lu, W. J. & Abrams, J. M., Aug 8 2022, In: Developmental cell. 57, 15, p. 1833-1846.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Developmental 100%
  • Protein Isoforms 66%
  • Binding Site 58%
  • Transcriptional Activation 50%
  • Protein 34%
  3 Scopus citations

• Generalized nuclear localization of retroelement transcripts

  Das, S., Jones, A. E. & Abrams, J. M., Dec 2022, In: Mobile DNA. 13, 1, 30.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retroelements 100%
  • RNA 23%
  • Cytoplasm 13%
  • Nuclear RNA 11%
  • Subcellular Fractions 10%
  1 Scopus citations
• 2021

  Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia

  Gu, Z., Liu, Y., Zhang, Y., Cao, H., Lyu, J., Wang, X., Wylie, A., Newkirk, S. J., Jones, A. E., Lee, M., Botten, G. A., Deng, M., Dickerson, K. E., Zhang, C. C., An, W., Abrams, J. M. & Xu, J., May 2021, In: Nature genetics. 53, 5, p. 672-682 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retroelements 100%
  • Myeloid Leukemia 93%
  • Acute Myeloid Leukemia 72%
  • Long Interspersed Nucleotide Elements 29%
  • Neoplasms 24%
  35 Scopus citations
• 2020

  Colorectal neoplasia among patients with and without human immunodeficiency virus

  Faqih, A., Singal, A. G., Fullington, H. M., Hewitt, B., Burstein, E., Gopal, P., Wylie, A., Abrams, J. & Murphy, C. C., Aug 2020, In: Cancer Epidemiology Biomarkers and Prevention. 29, 8, p. 1689-1691 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HIV 100%
  • Neoplasms 46%
  • Colorectal Neoplasms 46%
  • Adenoma 40%
  • Highly Active Antiretroviral Therapy 32%
  2 Scopus citations

• Drosophila GFAT1 and GFAT2 enzymes encode obligate developmental functions

  Chen, P., Visokay, S. & Abrams, J. M., 2020, In: Fly. p. 3-9 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • glucosamine 100%
  • fructose 6-phosphate 82%
  • Drosophila 79%
  • phosphates 65%
  • glutamine 60%
  5 Scopus citations

• P53 directly represses human LINE1 transposons

  Tiwari, B., Jones, A. E., Caillet, C. J., Das, S., Royer, S. K. & Abrams, J. M., Nov 1 2020, In: Genes and Development. 34, 21-22, p. 1439-1451 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retroelements 100%
  • Untranslated Regions 34%
  • RNA-Directed DNA Polymerase 29%
  • Histone Code 28%
  • p53 Genes 28%
  48 Scopus citations
• 2019

  Drosophila p53 directs nonapoptotic programs in postmitotic tissue

  Kurtz, P., Jones, A. E., Tiwari, B., Link, N., Wylie, A., Tracy, C., Krämer, H. & Abrams, J. M., 2019, In: Molecular biology of the cell. 30, 11, p. 1339-1351 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drosophila 100%
  • Chromatin 71%
  • Embryonic Structures 43%
  • Genes 43%
  • Head 39%
  10 Scopus citations
• 2018

  Meeting report: Mobile genetic elements and genome plasticity 2018

  Abrams, J. M., Arkhipova, I. R., Belfort, M., Boeke, J. D., Joan Curcio, M., Faulkner, G. J., Goodier, J. L., Lehmann, R. & Levin, H. L., Jun 22 2018, In: Mobile DNA. 9, 1, 21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interspersed Repetitive Sequences 100%
  • Congresses 70%
  • DNA Transposable Elements 61%
  • Genome 48%
  • Posters 30%
  3 Scopus citations

• Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

  Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V., & 149 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In: Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Terminology 100%
  • Cell Death 75%
  • Parthanatos 20%
  • Ferroptosis 17%
  • Immunogenic Cell Death 17%
  3834 Scopus citations

• Transposons, p53 and Genome Security

  Tiwari, B., Jones, A. E. & Abrams, J. M., Nov 2018, In: Trends in Genetics. 34, 11, p. 846-855 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Genome 100%
  • Neoplasms 47%
  • Carcinogenesis 37%
  • Transcription Factors 36%
  • Apoptosis 29%
  25 Scopus citations
• 2017

  A platform for interrogating cancer-associated p53 alleles

  D'Brot, A., Kurtz, P., Regan, E., Jakubowski, B. & Abrams, J. M., Jan 12 2017, In: Oncogene. 36, 2, p. 286-291 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alleles 100%
  • Diptera 88%
  • Biosensing Techniques 66%
  • Neoplasms 44%
  • p53 Genes 30%
  7 Scopus citations

• Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance

  Tiwari, B., Kurtz, P., Jones, A. E., Wylie, A., Amatruda, J. F., Boggupalli, D. P., Gonsalvez, G. B. & Abrams, J. M., Oct 9 2017, In: Current Biology. 27, 19, p. 3010-3016.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retroelements 100%
  • retrotransposons 85%
  • inheritance (genetics) 67%
  • germplasm 66%
  • Oocytes 31%
  20 Scopus citations
• 2016

  p53 genes function to restrain mobile elements

  Wylie, A., Jones, A. E., D’Brot, A., Lu, W. J., Kurtz, P., Moran, J. V., Rakheja, D., Chen, K., Hammer, R. E., Comerford, S. A., Amatruda, J. F. & Abrams, J. M., Jan 1 2016, In: Genes and Development. 30, 1, p. 64-77 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • p53 Genes 100%
  • Retroelements 89%
  • Long Interspersed Nucleotide Elements 34%
  • Alleles 33%
  • Neoplasms 29%
  135 Scopus citations

• p53 in the game of transposons

  Wylie, A., Jones, A. E. & Abrams, J. M., Nov 1 2016, In: BioEssays. 38, 11, p. 1111-1116 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutation 100%
  • Late Onset Disorders 39%
  • Neoplasms 38%
  • p53 Genes 32%
  • Animals 14%
  21 Scopus citations
• 2015

  Analysis of p53 Transactivation Domain Mutants Reveals Acad11 as a Metabolic Target Important for p53 Pro-Survival Function

  Jiang, D., LaGory, E. L., KenzelmannBrož, D., Bieging, K. T., Brady, C. A., Link, N., Abrams, J. M., Giaccia, A. J. & Attardi, L. D., Feb 24 2015, In: Cell Reports. 10, 7, p. 1096-1109 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Viability 100%
  • Transcriptional Activation 91%
  • Metabolic 81%
  • Fatty Acid 81%
  • Oxidative Phosphorylation 75%
  47 Scopus citations

• Essential versus accessory aspects of cell death: Recommendations of the NCCD 2015

  Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., Baehrecke, E. H., Bazan, N. G., Bertrand, M. J., Bianchi, K., Blagosklonny, M. V., Blomgren, K., Borner, C., Bredesen, D. E., Brenner, C., Campanella, M., & 88 othersCandi, E., Cecconi, F., Chan, F. K., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Di Daniele, N., Dixit, V. M., Dynlacht, B. D., El-Deiry, W. S., Fimia, G. M., Flavell, R. A., Fulda, S., Garrido, C., Gougeon, M. L., Green, D. R., Gronemeyer, H., Hajnoczky, G., Hardwick, J. M., Hengartner, M. O., Ichijo, H., Joseph, B., Jost, P. J., Kaufmann, T., Kepp, O., Klionsky, D. J., Knight, R. A., Kumar, S., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lugli, E., Madeo, F., Malorni, W., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Meier, P., Melino, S., Mizushima, N., Moll, U., Muñoz-Pinedo, C., Nuñez, G., Oberst, A., Panaretakis, T., Penninger, J. M., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H., Puthalakath, H., Rabinovich, G. A., Ravichandran, K. S., Rizzuto, R., Rodrigues, C. M., Rubinsztein, D. C., Rudel, T., Shi, Y., Simon, H. U., Stockwell, B. R., Szabadkai, G., Tait, S. W., Tang, H. L., Tavernarakis, N., Tsujimoto, Y., Vanden Berghe, T., Vandenabeele, P., Villunger, A., Wagner, E. F., Walczak, H., White, E., Wood, W. G., Yuan, J., Zakeri, Z., Zhivotovsky, B., Melino, G. & Kroemer, G., Jan 1 2015, In: Cell Death and Differentiation. 22, 1, p. 58-73 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Regulated Cell Death 100%
  • Cell Death 48%
  • Biochemical Phenomena 21%
  • Genetic Engineering 20%
  • Cytoprotection 19%
  747 Scopus citations

• Hid arbitrates collective cell death in the Drosophila wing

  Garcia-Hughes, G., Link, N., Ghosh, A. B. & Abrams, J. M., Nov 1 2015, In: Mechanisms of Development. 138, p. 349-355 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drosophila 100%
  • bursicon 84%
  • Cell Death 81%
  • Epithelium 49%
  • Epithelial Cells 46%
  6 Scopus citations

• Towards automatic image analysis and assessment of the multicellular apoptosis process

  Ziraldo, R., Link, N., Abrams, J. & Ma, L., May 1 2015, In: IET Image Processing. 9, 5, p. 424-433 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell death 100%
  • Image analysis 64%
  • Tissue 21%
  • Intravital Microscopy 15%
  • Microscopic examination 9%
  2 Scopus citations
• 2014

  Automatic image analysis of multicellular apoptosis process

  Ziraldo, R., Link, N., Abrams, J. & Ma, L., 2014, In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2014, p. 4643-4646 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell death 100%
  • Image analysis 64%
  • Apoptosis 41%
  • Drosophila 17%
  • Tissue 16%

• Automatic image analysis of multicellular apoptosis process

  Ziraldo, R., Link, N., Abrams, J. & Ma, L., Nov 2 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., p. 4643-4646 4 p. 6944659. (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Cell death 100%
  • Image analysis 64%
  • Apoptosis 41%
  • Drosophila 17%
  • Tissue 16%
  1 Scopus citations

• DNA loops specify p53 network responses

  Link, N. & Abrams, J. M., Jun 1 2014, In: Cell Cycle. 13, 11, p. 1659 1 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Scopus citations

• Genome-wide association analysis of radiation resistance in Drosophila melanogaster

  Vaisnav, M., Xing, C., Ku, H. C., Hwang, D., Stojadinovic, S., Pertsemlidis, A. & Abrams, J. M., Aug 14 2014, In: PloS one. 9, 8, e104858.

  Research output: Contribution to journal › Article › peer-review

  • radiation resistance 100%
  • genome-wide association study 85%
  • Drosophila melanogaster 80%
  • Genome-Wide Association Study 77%
  • Radiation 55%
  23 Scopus citations

• p53 activity is selectively licensed in the Drosophila stem cell compartment

  Wylie, A., Lu, W. J., D'Brot, A., Buszczak, M. & Abrams, J. M., Mar 11 2014, In: eLife. 2014, 3, e01530.

  Research output: Contribution to journal › Article › peer-review

  • Oncogenic 100%
  • Drosophila 66%
  • Stem Cells 52%
  • DNA Breaks 29%
  • Biosensing Techniques 28%
  47 Scopus citations

• The many roads to cell death: Discriminating between apoptosis, necrosis and autophagy

  Abrams, J., G.Telford, W. & Rollins, L., Dec 1 2014, In: Drug Discovery World. 16, 1, p. 41-46 6 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Cell Death 100%
  • Autophagy 90%
  • Necrosis 72%
  • Apoptosis 57%
  • Genotoxin 39%
  1 Scopus citations
• 2013

  A cell-based screening platform identifies novel mosquitocidal toxins

  O'Neal, M. A., Posner, B. A., Coates, C. J. & Abrams, J. M., Jul 2013, In: Journal of Biomolecular Screening. 18, 6, p. 688-694 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mosquitocidal 100%
  • Anopheles 68%
  • Pesticides 59%
  • Culicidae 57%
  • Toxin 51%
  5 Scopus citations

• A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans

  Link, N., Kurtz, P., O'Neal, M., Garcia-Hughes, G. & Abrams, J. M., Nov 15 2013, In: Genes and Development. 27, 22, p. 2433-2438 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Response Elements 100%
  • Chromatin 81%
  • Centromere 56%
  • Fluorescence In Situ Hybridization 46%
  • Drosophila 42%
  30 Scopus citations

• Tango7 directs cellular remodeling by the Drosophila apoptosome

  D'Brot, A., Chen, P., Vaishnav, M., Yuan, S., Akey, C. W. & Abrams, J. M., Aug 1 2013, In: Genes and Development. 27, 15, p. 1650-1655 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Apoptosomes 100%
  • Drosophila 57%
  • Caspases 50%
  • Giant Cells 13%
  • Spermatozoa 11%
  22 Scopus citations
• 2012

  Effectors of alcohol-induced cell killing in Drosophila

  Chen, P., Tu, X., Akdemir, F., Chew, S. K., Rothenfluh, A. & Abrams, J. M., Oct 2012, In: Cell Death and Differentiation. 19, 10, p. 1655-1663 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Drosophila 100%
  • Regulated Cell Death 83%
  • Alcohols 80%
  • Ethanol 45%
  • Apoptosomes 43%
  10 Scopus citations

• Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012

  Galluzzi, L., Vitale, I., Abrams, J. M., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., Dawson, T. M., Dawson, V. L., El-Deiry, W. S., Fulda, S., Gottlieb, E., Green, D. R., Hengartner, M. O., Kepp, O., Knight, R. A., Kumar, S., Lipton, S. A., Lu, X., Madeo, F., Malorni, W., & 13 othersMehlen, P., Nũez, G., Peter, M. E., Piacentini, M., Rubinsztein, D. C., Shi, Y., Simon, H. U., Vandenabeele, P., White, E., Yuan, J., Zhivotovsky, B., Melino, G. & Kroemer, G., Jan 2012, In: Cell Death and Differentiation. 19, 1, p. 107-120 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Terminology 100%
  • Cell Death 75%
  • Apoptosis 20%
  • Necrosis 17%
  • Autophagic Cell Death 15%
  2033 Scopus citations
• 2011

  Apoptotic cell death in Drosophila

  Galindo, K. & Abrams, J. M., Jan 1 2011, Apoptosis: Physiology and Pathology. Cambridge University Press, p. 407-411 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Apoptotic 100%
  • Cell Death 92%
  • Drosophila 81%
  • Apoptosis 53%
  • Nuclear Fragmentation 50%
• 2010

  Meiotic recombination provokes functional activation of the p53 regulatory network

  Lu, W. J., Chapo, J., Roig, L. & Abrams, J. M., Jun 4 2010, In: Science. 328, 5983, p. 1278-1281 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Recombination 100%
  • Type I DNA Topoisomerase 67%
  • Meiosis 60%
  • Proxy 54%
  • Germ Cells 51%
  75 Scopus citations
• 2009

  Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009

  Kroemer, G., Galluzzi, L., Vandenabeele, P., Abrams, J., Alnemri, E. S., Baehrecke, E. H., Blagosklonny, M. V., El-Deiry, W. S., Golstein, P., Green, D. R., Hengartner, M., Knight, R. A., Kumar, S., Lipton, S. A., Malorni, W., Nuñez, G., Peter, M. E., Tschopp, J., Yuan, J., Piacentini, M., & 2 othersZhivotovsky, B. & Melino, G., 2009, In: Cell Death and Differentiation. 16, 1, p. 3-11 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Terminology 100%
  • Cell Death 75%
  • Caspases 28%
  • Entosis 27%
  • Autophagic Cell Death 20%
  2348 Scopus citations

• Genome-wide silencing in Drosophila captures conserved apoptotic effectors

  Chew, S. K., Chen, P., Link, N., Galindo, K. A., Pogue, K. & Abrams, J. M., Jul 2 2009, In: Nature. 460, 7251, p. 123-127 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Drosophila 100%
  • Caspases 90%
  • Genome 72%
  • Apoptosis 65%
  • Apoptosomes 28%
  34 Scopus citations

• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  Galluzzi, L., Aaronson, S. A., Abrams, J., Alnemri, E. S., Andrews, D. W., Baehrecke, E. H., Bazan, N. G., Blagosklonny, M. V., Blomgren, K., Borner, C., Bredesen, D. E., Brenner, C., Castedo, M., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., De Laurenzi, V., De Maria, R., Deshmukh, M., Dynlacht, B. D., & 59 othersEl-Deiry, W. S., Flavell, R. A., Fulda, S., Garrido, C., Golstein, P., Gougeon, M. L., Green, D. R., Gronemeyer, H., Hajnóczky, G., Hardwick, J. M., Hengartner, M. O., Ichijo, H., Jäättelä, M., Kepp, O., Kimchi, A., Klionsky, D. J., Knight, R. A., Kornbluth, S., Kumar, S., Levine, B., Lipton, S. A., Lugli, E., Madeo, F., Malorni, W., Marine, J. C. W., Martin, S. J., Medema, J. P., Mehlen, P., Melino, G., Moll, U. M., Morselli, E., Nagata, S., Nicholson, D. W., Nicotera, P., Nuñez, G., Oren, M., Penninger, J., Pervaiz, S., Peter, M. E., Piacentini, M., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Scorrano, L., Simon, H. U., Steller, H., Tschopp, J., Tsujimoto, Y., Vandenabeele, P., Vitale, I., Vousden, K. H., Youle, R. J., Yuan, J., Zhivotovsky, B. & Kroemer, G., 2009, In: Cell Death and Differentiation. 16, 8, p. 1093-1107 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Eukaryota 100%
  • Cell Death 73%
  • Guidelines 62%
  • Physiological Phenomena 16%
  • Biomedical Research 16%
  569 Scopus citations

• P53 ancestry: Gazing through an evolutionary lens

  Lu, W. J., Amatruda, J. F. & Abrams, J. M., Oct 2009, In: Nature Reviews Cancer. 9, 10, p. 758-762 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lenses 100%
  • p53 Genes 58%
  • Neoplasms 34%
  • Genes 21%
  • Therapeutics 8%
  98 Scopus citations

• Radiation Responses in Drosophila

  Lu, W. J., Sogame, N. & Abrams, J. M., Jan 1 2009, Handbook of Cell Signaling, Second Edition. Elsevier, Vol. 3. p. 2159-2163 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ionizing Radiation 100%
  • Replication Protein C 85%
  • Drosophila 76%
  • Schizosaccharomyces 66%
  • Radiation 61%

• The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death

  Galindo, K. A., Lu, W. J., Park, J. H. & Abrams, J. M., Jan 15 2009, In: Development. 136, 2, p. 275-283 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Drosophila 100%
  • Apoptosis 65%
  • Cytochromes c 58%
  • Caspases 54%
  • bcl-2 Genes 35%
  46 Scopus citations
• 2008

  No death without life: Vital functions of apoptotic effectors

  Galluzzi, L., Joza, N., Tasdemir, E., Maiuri, M. C., Hengartner, M., Abrams, J. M., Tavernarakis, N., Penninger, J., Madeo, F. & Kroemer, G., Jul 2008, In: Cell Death and Differentiation. 15, 7, p. 1113-1123 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Death 100%
  • Caspases 66%
  • endonuclease G 55%
  • Caenorhabditis elegans Proteins 51%
  • Apoptosis Inducing Factor 46%
  221 Scopus citations

• p53: The Janus of autophagy?

  Levine, B. & Abrams, J., Jun 2008, In: Nature cell biology. 10, 6, p. 637-639 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autophagy 100%
  • Neoplasms 33%
  • Nutrients 29%
  188 Scopus citations

• The molecular archaeology of a mitochondrial death effector: AIF in Drosophila

  Joza, N., Galindo, K., Pospisilik, J. A., Benit, P., Rangachari, M., Kanitz, E. E., Nakashima, Y., Neely, G. G., Rustin, P., Abrams, J. M., Kroemer, G. & Penninger, J. M., Jun 2008, In: Cell Death and Differentiation. 15, 6, p. 1009-1018 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Archaeology 100%
  • Apoptosis Inducing Factor 85%
  • Drosophila melanogaster 66%
  • Drosophila 56%
  • Caspases 34%
  43 Scopus citations
• 2007

  A collective form of cell death requires homeodomain interacting protein kinase

  Link, N., Chen, P., Lu, W. J., Pogue, K., Chuong, A., Mata, M., Checketts, J. & Abrams, J. M., Aug 13 2007, In: Journal of Cell Biology. 178, 4, p. 567-574 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Homeodomain Proteins 100%
  • Protein Kinases 68%
  • Apoptosomes 59%
  • Epithelium 56%
  • Cell Death 56%
  41 Scopus citations

• Noncanonical cell death pathways act during Drosophila oogenesis

  Peterson, J. S., Bass, B. P., Jue, D., Rodriguez, A., Abrams, J. M. & McCall, K., Jun 2007, In: Genesis (United States). 45, 6, p. 396-404 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oogenesis 100%
  • Drosophila 69%
  • Cell Death 56%
  • Apoptosis 45%
  • Caspases 32%
  30 Scopus citations

• p53 directs focused genomic responses in Drosophila

  Akdemir, F., Christich, A., Sogame, N., Chapo, J. & Abrams, J. M., Aug 9 2007, In: Oncogene. 26, 36, p. 5184-5193 10 p.

  Research output: Contribution to journal › Article › peer-review

  • p53 Genes 100%
  • Drosophila 84%
  • Genomic Instability 49%
  • Effector Caspases 33%
  • Genes 27%
  69 Scopus citations
• 2006

  Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death

  Akdemir, F., Farkaš, R., Chen, P., Juhasz, G., Medved'ova, L., Sass, M., Wang, L., Wang, X., Chittaranjan, S., Gorski, S. M., Rodriguez, A. & Abrams, J. M., Apr 2006, In: Development. 133, 8, p. 1457-1465 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Apoptosomes 100%
  • Autophagy 59%
  • Cell Death 47%
  • Apoptosis 37%
  • Autophagic Cell Death 29%
  83 Scopus citations

• Lessons from p53 in non-mammalian models

  Lu, W. J. & Abrams, J. M., Jun 2006, In: Cell Death and Differentiation. 13, 6, p. 909-912 4 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  45 Scopus citations
• 2005

  Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis

  Sang, T. K., Li, C., Liu, W., Rodriguez, A., Abrams, J. M., Zipursky, S. L. & Jackson, G. R., Feb 1 2005, In: Human molecular genetics. 14, 3, p. 357-372 16 p.

  Research output: Contribution to journal › Article › peer-review

  • polyglutamine 100%
  • Drosophila 71%
  • Cell Death 49%
  • Huntington Disease 36%
  • Pathological Protein Aggregation 20%
  56 Scopus citations

• Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span

  Bauer, J. H., Poon, P. C., Glatt-Deeley, H., Abrams, J. M. & Helfand, S. L., Nov 22 2005, In: Current Biology. 15, 22, p. 2063-2068 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Drosophila melanogaster 100%
  • Longevity 82%
  • Resistance 57%
  • Genotoxic 54%
  • Shortening 51%
  98 Scopus citations
• 2004

  Bifunctional killing activity encoded by conserved reaper proteins

  Chen, P., Ho, S. I., Shi, Z. & Abrams, J. M., Jul 2004, In: Cell Death and Differentiation. 11, 7, p. 704-713 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Drosophila 100%
  • Apoptosis 98%
  • Proteins 59%
  • Blister 56%
  • Cell Death 40%
  24 Scopus citations

• Caspase activation - Stepping on the gas or releasing the brakes? Lessons from humans and flies

  Salvesen, G. S. & Abrams, J. M., Apr 12 2004, In: Oncogene. 23, 16 REV. ISS. 2, p. 2774-2784 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Diptera 100%
  • Caspases 93%
  • Gases 77%
  • Enzyme Precursors 59%
  • Peptide Hydrolases 57%
  217 Scopus citations