Research output per year
Research output per year
- 1 - 50 out of 80 results
Search results
-
2018
Fusion surface structure, function, and dynamics of gamete fusogen HAP2
Feng, J., Dong, X., Pinello, J., Zhang, J., Lu, C., Iacob, R. E., Engen, J. R., Snell, W. J. & Springer, T. A., Oct 2018, In: eLife. 7, e39772.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2017
Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum
Angrisano, F., Sala, K. A., Da, D. F., Liu, Y., Pei, J., Grishin, N. V., Snell, W. J. & Blagborough, A. M., Dec 5 2017, In: Cell Reports. 21, 10, p. 2868-2878 11 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
The Ancient Gamete Fusogen HAP2 Is a Eukaryotic Class II Fusion Protein
Fédry, J., Liu, Y., Péhau-Arnaudet, G., Pei, J., Li, W., Tortorici, M. A., Traincard, F., Meola, A., Bricogne, G., Grishin, N. V., Snell, W. J., Rey, F. A. & Krey, T., Feb 23 2017, In: Cell. 168, 5, p. 904-915.e10Research output: Contribution to journal › Article › peer-review
Open Access126 Scopus citations -
2016
Endogenous B-ring oxysterols inhibit the hedgehog component smoothened in a manner distinct from cyclopamine or side-chain oxysterols
Sever, N., Mann, R. K., Xu, L., Snell, W. J., Hernandez-Lara, C. I., Porter, N. A. & Beachy, P. A., May 24 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 5904-5909 6 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
2015
Characterization, mutagenesis and mechanistic analysis of an ancient algal sterol C24-methyltransferase: Implications for understanding sterol evolution in the green lineage
Haubrich, B. A., Collins, E. K., Howard, A. L., Wang, Q., Snell, W. J., Miller, M. B., Thomas, C. D., Pleasant, S. K. & Nes, W. D., May 17 2015, In: Phytochemistry. 113, p. 64-72 9 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction
Liu, Y., Pei, J., Grishin, N. & Snell, W. J., 2015, In: Development (Cambridge). 142, 5, p. 962-971 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding
Cao, M., Ning, J., Hernandez-Lara, C. I., Belzile, O., Wang, Q., Dutcher, S. K., Liu, Y. & Snell, W. J., Feb 17 2015, In: eLife. 2015, 4, e05242.Research output: Contribution to journal › Article › peer-review
99 Scopus citations -
2014
Fertilization: A sticky sperm protein in plants
Dresselhaus, T. & Snell, W. J., Feb 17 2014, In: Current Biology. 24, 4, p. R164-R166Research output: Contribution to journal › Short survey › peer-review
10 Scopus citations -
Organelle size: A cilium length signal regulates IFT cargo loading
Pan, J. & Snell, W. J., Jan 20 2014, In: Current Biology. 24, 2, p. R75-R78Research output: Contribution to journal › Short survey › peer-review
7 Scopus citations -
2013
Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length
Cao, M., Meng, D., Wang, L., Bei, S., Snell, W. J. & Pan, J., Jul 23 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 30, p. 12337-12342 6 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates
Ning, J., Otto, T. D., Pfander, C., Schwach, F., Brochet, M., Bushell, E., Goulding, D., Sanders, M., Lefebvre, P. A., Pei, J., Grishin, N. V., Vanderlaan, G., Billker, O. & Snell, W. J., May 15 2013, In: Genes and Development. 27, 10, p. 1198-1215 18 p.Research output: Contribution to journal › Article › peer-review
72 Scopus citations -
Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT
Belzile, O., Hernandez-Lara, C. I., Wang, Q. & Snell, W. J., Aug 5 2013, In: Current Biology. 23, 15, p. 1460-1465 6 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
2012
Evolutionarily conserved Δ25(27)-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii
Miller, M. B., Haubrich, B. A., Wang, Q., Snell, W. J. & Nes, W. D., Aug 2012, In: Journal of lipid research. 53, 8, p. 1636-1645 10 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Plant gametes do fertilization with a twist
Snell, W. J., Nov 23 2012, In: Science. 338, 6110, p. 1038-1039 2 p.Research output: Contribution to journal › Short survey › peer-review
2 Scopus citations -
2011
The phosphorylation state of an aurora-like kinase marks the length of growing flagella in Chlamydomonas
Luo, M., Cao, M., Kan, Y., Li, G., Snell, W. & Pan, J., Apr 12 2011, In: Current Biology. 21, 7, p. 586-591 6 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
2010
Membrane fusion triggers rapid degradation of two gamete-specific, fusion-essential proteins in a membrane block to polygamy in Chlamydomonas
Liu, Y., Misamore, M. J. & Snell, W. J., May 1 2010, In: Development. 137, 9, p. 1473-1481 9 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
The ciliary membrane
Rohatgi, R. & Snell, W. J., Aug 2010, In: Current Opinion in Cell Biology. 22, 4, p. 541-546 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access136 Scopus citations -
2009
A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas
Piao, T., Luo, M., Wang, L., Guo, Y., Li, D., Li, P., Snell, W. J. & Pan, J., Mar 24 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 12, p. 4713-4718 6 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
Flagellar Adhesion, Flagellar-Generated Signaling, and Gamete Fusion during Mating
Snell, W. J. & Goodenough, U. W., 2009, The Chlamydomonas Sourcebook 3-Vol set. Elsevier Inc., Vol. 3. p. 369-394 26 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
23 Scopus citations -
Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm
Ellerman, D. A., Pei, J., Gupta, S., Snell, W. J., Myles, D. & Primakoff, P., Dec 2009, In: Molecular Reproduction and Development. 76, 12, p. 1188-1199 12 p.Research output: Contribution to journal › Article › peer-review
Open Access95 Scopus citations -
SnapShot: Intraflagellar Transport
Cole, D. G. & Snell, W. J., May 15 2009, In: Cell. 137, 4, p. 784-784.e1Research output: Contribution to journal › Short survey › peer-review
49 Scopus citations -
2008
The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes
Liu, Y., Tewari, R., Ning, J., Blagborough, A. M., Garbom, S., Pei, J., Grishin, N. V., Steele, R. E., Sinden, R. E., Snell, W. J. & Billker, O., Apr 15 2008, In: Genes and Development. 22, 8, p. 1051-1068 18 p.Research output: Contribution to journal › Article › peer-review
245 Scopus citations -
2007
A ciliary timer for S-phase entry
Snell, W. J. & Golemis, E. A., Oct 2007, In: Nature Reviews Molecular Cell Biology. 8, 10, p. 1PResearch output: Contribution to journal › Letter › peer-review
3 Scopus citations -
The Primary Cilium: Keeper of the Key to Cell Division
Pan, J. & Snell, W., Jun 29 2007, In: Cell. 129, 7, p. 1255-1257 3 p.Research output: Contribution to journal › Short survey › peer-review
136 Scopus citations -
2006
Intraflagellar Transport Particles Participate Directly in Cilium-Generated Signaling in Chlamydomonas
Wang, Q., Pan, J. & Snell, W. J., May 5 2006, In: Cell. 125, 3, p. 549-562 14 p.Research output: Contribution to journal › Article › peer-review
121 Scopus citations -
2005
Chlamydomonas shortens its flagella by activating axonemal disassembly, stimulating IFT particle trafficking, and blocking anterograde cargo loading
Pan, J. & Snell, W. J., Sep 2005, In: Developmental cell. 9, 3, p. 431-438 8 p.Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
Cilium-generated signaling and cilia-related disorders
Pan, J., Wang, Q. & Snell, W. J., Apr 2005, In: Laboratory Investigation. 85, 4, p. 452-463 12 p.Research output: Contribution to journal › Short survey › peer-review
202 Scopus citations -
2004
An aurora kinase is essential for flagellar disassembly in Chlamydomonas
Pan, J., Wang, Q. & Snell, W. J., Mar 2004, In: Developmental cell. 6, 3, p. 445-451 7 p.Research output: Contribution to journal › Article › peer-review
126 Scopus citations -
Cilia and flagella revealed: From flagellar assembly in Chlamydomonas to human obesity disorders
Snell, W. J., Pan, J. & Wang, Q., Jun 11 2004, In: Cell. 117, 6, p. 693-697 5 p.Research output: Contribution to journal › Review article › peer-review
126 Scopus citations -
2003
Flagellar adhesion between mating type plus and mating type minus gametes activates a flagellar protein-tyrosine kinase during fertilization in Chlamydomonas
Wang, Q. & Snell, W. J., Aug 29 2003, In: Journal of Biological Chemistry. 278, 35, p. 32936-32942 7 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Kinesin II and regulated intraflagellar transport of Chlamydomonas aurora protein kinase
Pan, J. & Snell, W. J., Jun 1 2003, In: Journal of cell science. 116, 11, p. 2179-2186 8 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
Protein transport and signal transduction during fertilization in Chlamydomonas
Pan, J., Misamore, M. J., Wang, Q. & Snell, W. J., Jul 1 2003, In: Traffic. 4, 7, p. 452-459 8 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
The Chlamydomonas Fus1 protein is present on the mating type plus fusion organelle and required for a critical membrane adhesion event during fusion with minus gametes
Misamore, M. J., Gupta, S. & Snell, W. J., Jun 1 2003, In: Molecular biology of the cell. 14, 6, p. 2530-2542 13 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Scopus citations -
2002
An algal nucleus-encoded subunit of mitochondrial ATP synthase rescues a defect in the analogous human mitochondrial-encoded subunit
Ojaimi, J., Pan, J., Santra, S., Snell, W. J. & Schon, E. A., Nov 1 2002, In: Molecular biology of the cell. 13, 11, p. 3836-3844 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Kinesin-II is required for flagellar sensory transduction during fertilization in Chlamydomonas
Pan, J. & Snell, W. J., 2002, In: Molecular biology of the cell. 13, 4, p. 1417-1426 10 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
2001
Ectopic expression of a Chlamydomonas mt+-specific homeodomain protein in mt- gametes initiates zygote development without gamete fusion
Zhao, H., Lu, M., Singh, R. & Snell, W. J., Oct 15 2001, In: Genes and Development. 15, 20, p. 2767-2777 11 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
2000
Regulated targeting of a protein kinase into a intact flagellum: An aurora/IpI1p-like protein kinase translocates from the cell body into the flagella during gamete activation in Chlamydomonas
Pan, J. & Snell, W. J., Aug 4 2000, In: Journal of Biological Chemistry. 275, 31, p. 24106-24114 9 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Signal transduction during fertilization in the unicellular green alga, Chlamydomonas
Pan, J. & Snell, W. J., 2000, In: Current Opinion in Microbiology. 3, 6, p. 596-602 7 p.Research output: Contribution to journal › Review article › peer-review
70 Scopus citations -
1999
Flagellar adhesion between mt+ and mt- Chlamydomonas gametes regulates phosphorylation of the mt+-specific homeodomain protein GSP1
Wilson, N. F., O'Connell, J. S., Lu, M. & Snell, W. J., Nov 26 1999, In: Journal of Biological Chemistry. 274, 48, p. 34383-34388 6 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
1998
A gamete-specific, sex-limited homeodomain protein in Chlamydomonas
Kurvari, V., Grishin, N. V. & Snell, W. J., Dec 28 1998, In: Journal of Cell Biology. 143, 7, p. 1971-1980 10 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Microvilli and cell-cell fusion during fertilization
Wilson, N. F. & Snell, W. J., Mar 1998, In: Trends in Cell Biology. 8, 3, p. 93-96 4 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
1997
The Chlamydomonas mating type plus fertilization tubule, a prototypic cell fusion organelle: Isolation, characterization, and in vitro adhesion to mating type minus gametes
Wilson, N. F., Foglesong, M. J. & Snell, W. J., Jun 30 1997, In: Journal of Cell Biology. 137, 7, p. 1537-1553 17 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
1996
Cell adhesion-dependent inactivation of a soluble protein kinase during fertilization in Chlamydomonas
Zhang, Y., Luo, Y., Emmett, K. & Snell, W. J., Apr 1996, In: Molecular biology of the cell. 7, 4, p. 515-527 13 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Molecular cloning of a protein kinase whose phosphorylation is regulated by gametic adhesion during Chlamydomonas fertilization
Kurvari, V., Zhang, Y., Luo, Y. & Snell, W. J., Jan 9 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 1, p. 39-43 5 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
SksC, a fertilization-related protein kinase in chlamydomonas, is expressed throughout the cell cycle and gametogenesis, and a phosphorylated form is present in both flagella and cell bodies
Kurvari, V. & Snell, W. J., Nov 1 1996, In: Biochemical and Biophysical Research Communications. 228, 1, p. 45-54 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
The molecules of mammalian fertilization
Snell, W. J. & White, J. M., May 31 1996, In: Cell. 85, 5, p. 629-637 9 p.Research output: Contribution to journal › Review article › peer-review
214 Scopus citations -
1995
Chapter 64 Flagellar Adenylyl Cyclases in Chlamydomonas
Zhang, Y. & Snell, W. J., Jan 1 1995, In: Methods in cell biology. 47, C, p. 459-465 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Increased transcript levels of a methionine synthase during adhesion-induced activation of Chlamydomonas reinhardtii gametes
Kurvari, V., Qian, F. & Snell, W. J., Dec 1995, In: Plant Molecular Biology. 29, 6, p. 1235-1252 18 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
1994
Flagellar adhesion-dependent regulation of Chlamydomonas adenylyl cyclase in vitro: A possible role for protein kinases in sexual signaling
Zhang, Y. & Snell, W. J., May 1994, In: Journal of Cell Biology. 125, 3, p. 617-624 8 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
1993
Differential regulation of adenylylcyclases in vegetative and gametic flagella of Chlamydomonas
Zhang, Y. & Snell, W. J., Jan 25 1993, In: Journal of Biological Chemistry. 268, 3, p. 1786-1791 6 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations