Research output per year
Research output per year
- 42 results
Search results
-
2023
Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
Hwang, S. H., White, K. A., Somatilaka, B. N., Wang, B. & Mukhopadhyay, S., Nov 9 2023, In: PLoS genetics. 19, 11 November, e1011028.Research output: Contribution to journal › Article › peer-review
Open Access -
Human IFT-A complex structures provide molecular insights into ciliary transport
Jiang, M., Palicharla, V. R., Miller, D., Hwang, S. H., Zhu, H., Hixson, P., Mukhopadhyay, S. & Sun, J., Apr 2023, In: Cell Research. 33, 4, p. 288-298 11 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2022
A pathogenic variant of TULP3 causes renal and hepatic fibrocystic disease
Jafari Khamirani, H., Palicharla, V. R., Dastgheib, S. A., Dianatpour, M., Imanieh, M. H., Tabei, S. S., Besse, W., Mukhopadhyay, S. & Liem, K. F., Oct 7 2022, In: Frontiers in Genetics. 13, 1021037.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Cilia-Localized Counterregulatory Signals as Drivers of Renal Cystogenesis
Walker, R. V., Maranto, A., Palicharla, V. R., Hwang, S. H., Mukhopadhyay, S. & Qian, F., Jun 23 2022, In: Frontiers in Molecular Biosciences. 9, 936070.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Studying Hedgehog Signaling During Mouse Neural Tube Development
Constable, S., White, K., Somatilaka, B. N. & Mukhopadhyay, S., 2022, Methods in Molecular Biology. Humana Press Inc., p. 59-71 13 p. (Methods in Molecular Biology; vol. 2374).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2021
Ciliary and extraciliary gpr161 pools repress hedgehog signaling in a tissue-specific manner
Hwang, S. H., Somatilaka, B. N., White, K. & Mukhopadhyay, S., 2021, In: eLife. 10Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Developmental and regenerative paradigms of cilia regulated hedgehog signaling
Kopinke, D., Norris, A. M. & Mukhopadhyay, S., Feb 2021, In: Seminars in Cell and Developmental Biology. 110, p. 89-103 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access50 Scopus citations -
Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development
Kim, S. E., Robles-Lopez, K., Cao, X., Liu, K., Chothani, P. J., Bhavani, N., Rahman, L., Mukhopadhyay, S., Wlodarczyk, B. J. & Finnell, R. H., Nov 23 2021, In: Frontiers in Genetics. 12, 761418.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2020
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling
Somatilaka, B. N., Hwang, S. H., Palicharla, V. R., White, K. A., Badgandi, H., Shelton, J. M. & Mukhopadhyay, S., Sep 28 2020, In: Developmental cell. 54, 6, p. 710-726.e8Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Ubiquitin Tunes Hedgehog in Matters of the Heart
Constable, S. & Mukhopadhyay, S., Nov 23 2020, In: Developmental cell. 55, 4, p. 385-386 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
2019
Cellular signalling by primary cilia in development, organ function and disease
Anvarian, Z., Mykytyn, K., Mukhopadhyay, S., Pedersen, L. B. & Christensen, S. T., Apr 1 2019, In: Nature Reviews Nephrology. 15, 4, p. 199-219 21 p.Research output: Contribution to journal › Review article › peer-review
435 Scopus citations -
Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities
Shimada, I. S., Somatilaka, B. N., Hwang, S. H., Anderson, A. G., Shelton, J. M., Rajaram, V., Konopka, G. & Mukhopadhyay, S., Jun 1 2019, In: Developmental Biology. 450, 1, p. 47-62 16 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Dominant negative GPR161 rare variants are risk factors of human spina bifida
Kim, S. E., Lei, Y., Hwang, S. H., Wlodarczyk, B. J., Mukhopadhyay, S., Shaw, G. M., Ross, M. E. & Finnell, R. H., Jan 15 2019, In: Human molecular genetics. 28, 2, p. 200-208 9 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia
Hwang, S. H., Somatilaka, B. N., Badgandi, H., Palicharla, V. R., Walker, R., Shelton, J. M., Qian, F. & Mukhopadhyay, S., Mar 4 2019, In: Current Biology. 29, 5, p. 790-802.e5Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2018
Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis
Shimada, I. S., Hwang, S. H., Somatilaka, B. N., Wang, X., Skowron, P., Kim, J., Kim, M., Shelton, J. M., Rajaram, V., Xuan, Z., Taylor, M. D. & Mukhopadhyay, S., Jan 30 2018, In: Cell Reports. 22, 5, p. 1169-1184 16 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner
Hwang, S. H., White, K. A., Somatilaka, B. N., Shelton, J. M., Richardson, J. A. & Mukhopadhyay, S., Jan 2018, In: Development (Cambridge). 145, 1, dev154054.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2017
G-protein-coupled receptor signaling and neural tube closure defects
Shimada, I. S. & Mukhopadhyay, S., Jan 30 2017, In: Birth Defects Research. 109, 2, p. 129-139 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Trafficking to the primary cilium membrane
Mukhopadhyay, S., Badgandi, H. B., Hwang, S. H., Somatilaka, B., Shimada, I. S. & Pal, K., Jan 15 2017, In: Molecular biology of the cell. 28, 2, p. 233-239 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access53 Scopus citations -
Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins
Badgandi, H. B., Hwang, S. H., Shimada, I. S., Loriot, E. & Mukhopadhyay, S., Mar 6 2017, In: The Journal of cell biology. 216, 3, p. 743-760 18 p.Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Using primary neurosphere cultures to study primary cilia
Shimada, I. S., Badgandi, H., Somatilaka, B. N. & Mukhopadhyay, S., Apr 14 2017, In: Journal of Visualized Experiments. 2017, 122, e55315.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2016
Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium
Pal, K., Hwang, S. H., Somatilaka, B., Badgandi, H., Jackson, P. K., DeFea, K. & Mukhopadhyay, S., Mar 28 2016, In: Journal of Cell Biology. 212, 7, p. 861-875 15 p.Research output: Contribution to journal › Article › peer-review
Open Access91 Scopus citations -
2015
G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning
Hwang, S. H. & Mukhopadhyay, S., Jan 2015, In: Birth Defects Research Part A - Clinical and Molecular Teratology. 103, 1, p. 12-19 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Primary cilium and sonic hedgehog signaling during neural tube patterning: Role of GPCRs and second messengers
Pal, K. & Mukhopadhyay, S., Apr 1 2015, In: Developmental Neurobiology. 75, 4, p. 337-348 12 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Studying G protein-coupled receptors: Immunoblotting, immunoprecipitation, phosphorylation, surface labeling, and cross-linking protocols
Pal, K., Badgandi, H. & Mukhopadhyay, S., 2015, In: Methods in cell biology. 127, p. 303-322 20 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
TCTEX1D2, a potential link to skeletal ciliopathies
Mukhopadhyay, S., Feb 1 2015, In: Cell Cycle. 14, 3, p. 293-294 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
2014
G-protein-coupled receptors, hedgehog signaling and primary cilia
Mukhopadhyay, S. & Rohatgi, R., Sep 2014, In: Seminars in Cell and Developmental Biology. 33, p. 63-72 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access118 Scopus citations -
2013
Cilia, tubby mice, and obesity
Mukhopadhyay, S. & Jackson, P. K., Jan 2013, In: Cilia. 2, 1, 1.Research output: Contribution to journal › Comment/debate › peer-review
12 Scopus citations -
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the sonic hedgehog pathway via cAMP signaling
Mukhopadhyay, S., Wen, X., Ratti, N., Loktev, A., Rangell, L., Scales, S. J. & Jackson, P. K., Jan 17 2013, In: Cell. 152, 1-2, p. 210-223 14 p.Research output: Contribution to journal › Article › peer-review
343 Scopus citations -
2011
An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium
Wright, K. J., Baye, L. M., Olivier-Mason, A., Mukhopadhyay, S., Sang, L., Kwong, M., Wang, W., Pretorius, P. R., Sheffield, V. C., Sengupta, P., Slusarski, D. C. & Jackson, P. K., Nov 15 2011, In: Genes and Development. 25, 22, p. 2347-2360 14 p.Research output: Contribution to journal › Article › peer-review
177 Scopus citations -
The tubby family proteins
Mukhopadhyay, S. & Jackson, P. K., Jun 28 2011, In: Genome biology. 12, 6, 225.Research output: Contribution to journal › Review article › peer-review
97 Scopus citations -
2010
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
Mukhopadhyay, S., Wen, X., Chih, B., Nelson, C. D., Lane, W. S., Scales, S. J. & Jackson, P. K., Oct 1 2010, In: Genes and Development. 24, 19, p. 2180-2193 14 p.Research output: Contribution to journal › Article › peer-review
305 Scopus citations -
2009
Cis-regulatory mechanisms of gene expression in an olfactory neuron type in Caenorhabditis elegans
Nokes, E. B., Van Der Linden, A. M., Winslow, C., Mukhopadhyay, S., Ma, K. & Sengupta, P., Dec 2009, In: Developmental Dynamics. 238, 12, p. 3080-3092 13 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2008
Elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8
Omori, Y., Zhao, C., Saras, A., Mukhopadhyay, S., Kim, W., Furukawa, T., Sengupta, P., Veraksa, A. & Malicki, J., 2008, In: Nature cell biology. 10, 4, p. 437-444 8 p.Research output: Contribution to journal › Article › peer-review
180 Scopus citations -
Sensory Signaling-Dependent Remodeling of Olfactory Cilia Architecture in C. elegans
Mukhopadhyay, S., Lu, Y., Shaham, S. & Sengupta, P., May 13 2008, In: Developmental cell. 14, 5, p. 762-774 13 p.Research output: Contribution to journal › Article › peer-review
101 Scopus citations -
2007
Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans
Mukhopadhyay, S., Lu, Y., Qin, H., Lanjuin, A., Shaham, S. & Sengupta, P., Jun 20 2007, In: EMBO Journal. 26, 12, p. 2966-2980 15 p.Research output: Contribution to journal › Article › peer-review
82 Scopus citations -
2004
Identification of thermosensory and olfactory neuron-specific genes via expression profiling of single neuron types
Colosimo, M. E., Brown, A., Mukhopadhyay, S., Gabel, C., Lanjuin, A. E., Samuel, A. D. T. & Sengupta, P., Dec 29 2004, In: Current Biology. 14, 24, p. 2245-2251 7 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
Platelet storage under in vitro condition is associated with calcium-dependent apoptosis-like lesions and novel reorganization in platelet cytoskeleton
Wadhawan, V., Karim, Z. A., Mukhopadhyay, S., Gupta, R., Dikshit, M. & Dash, D., Feb 15 2004, In: Archives of Biochemistry and Biophysics. 422, 2, p. 183-190 8 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Sustained stimulation of platelet thrombin receptor is associated with tyrosine dephosphorylation of a novel p67 peptide in a manner regulated by extracellular calcium
Karim, Z. A., Mukhopadhyay, S., Ramars, A. S. S. & Dash, D., Aug 23 2004, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1693, 2, p. 147-157 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2002
Factor VIII gene polymorphisms in North Indian population: A consensus algorithm for carrier analysis of hemophilia A
Srinivasan, A., Mukhopadhyay, S., Karim, Z. A., Gupta, R. K., Gupta, A., Wadhawan, V., Shukla, J., Singh, V. P. & Dash, D., Nov 2002, In: Clinica Chimica Acta. 325, 1-2, p. 177-181 5 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Regulation of postaggregation events induced by protease-activated receptor 1 ligation in human platelets: Evidence of differential signaling pathways
Ramars, A. S. S., Mukhopadhyay, S. & Dash, D., Feb 15 2002, In: Archives of Biochemistry and Biophysics. 398, 2, p. 253-260 8 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
2001
Bruton's tyrosine kinase associates with the actin-based cytoskeleton in activated platelets
Mukhopadhyay, S., Ramars, A. S. S. & Dash, D., 2001, In: Journal of Cellular Biochemistry. 81, 4, p. 659-665 7 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Bruton's tyrosine kinase is a substrate of calpain in human platelets
Mukhopadhyay, S., Ramars, A. S. S., Ochs, H. D. & Dash, D., Sep 7 2001, In: FEBS Letters. 505, 1, p. 37-41 5 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations