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2020

Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles

Gao, X., Zhang, Z., Mashimo, T., Shen, B., Nyagilo, J., Wang, H., Wang, Y., Liu, Z., Mulgaonkar, A., Hu, X. L., Piccirillo, S. G. M., Eskiocak, U., Davé, D. P., Qin, S., Yang, Y., Sun, X., Fu, Y. X., Zong, H., Sun, W., Bachoo, R. M. & 1 others, Ge, W. P., Feb 25 2020, In : Cell Reports. 30, 8, p. 2489-2500.e5

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Hispanic/Latino Patients with Gastric Adenocarcinoma Have Distinct Molecular Profiles Including a High Rate of Germline CDH1 Variants

Wang, S. C., Yeu, Y., Hammer, S. T. G., Xiao, S., Zhu, M., Hong, C., Clemenceau, J. R., Yoon, L. Y., Nassour, I., Shen, J., Agarwal, D., Reznik, S. I., Mansour, J. C., Yopp, A. C., Zhu, H., Hwang, T. H. & Porembka, M. R., Jun 1 2020, In : Cancer research. 80, 11, p. 2114-2124 11 p.

Research output: Contribution to journalArticle

Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing

Li, K., Liu, Y., Cao, H., Zhang, Y., Gu, Z., Liu, X., Yu, A., Kaphle, P., Dickerson, K. E., Ni, M. & Xu, J., Dec 1 2020, In : Nature communications. 11, 1, 485.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Metabolic heterogeneity confers differences in melanoma metastatic potential

Tasdogan, A., Faubert, B., Ramesh, V., Ubellacker, J. M., Shen, B., Solmonson, A., Murphy, M. M., Gu, Z., Gu, W., Martin, M., Kasitinon, S. Y., Vandergriff, T., Mathews, T. P., Zhao, Z., Schadendorf, D., DeBerardinis, R. J. & Morrison, S. J., Jan 2 2020, In : Nature. 577, 7788, p. 115-120 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury

Lin, Y. H., Zhang, S., Zhu, M., Lu, T., Chen, K., Wen, Z., Wang, S., Xiao, G., Luo, D., Jia, Y., Li, L., MacConmara, M., Hoshida, Y., Singal, A. G., Yopp, A., Wang, T. & Zhu, H., May 2020, In : Gastroenterology. 158, 6, p. 1698-1712.e14

Research output: Contribution to journalArticle

2 Scopus citations

Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9

Liu, X., Chen, Y., Zhang, Y., Liu, Y., Liu, N., Botten, G. A., Cao, H., Orkin, S. H., Zhang, M. Q. & Xu, J., Mar 5 2020, In : Genome biology. 21, 1, 59.

Research output: Contribution to journalArticle

Open Access

Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies

Li, K., Zhang, Y., Liu, X., Liu, Y., Gu, Z., Cao, H., Dickerson, K. E., Chen, M., Chen, W., Shao, Z., Ni, M. & Xu, J., May 1 2020, In : Cancer discovery. 10, 5, p. 724-745 22 p.

Research output: Contribution to journalArticle

PET imaging of occult tumours by temporal integration of tumour-acidosis signals from pH-sensitive 64Cu-labelled polymers

Huang, G., Zhao, T., Wang, C., Nham, K., Xiong, Y., Gao, X., Wang, Y., Hao, G., Ge, W. P., Sun, X., Sumer, B. D. & Gao, J., Mar 1 2020, In : Nature Biomedical Engineering. 4, 3, p. 314-324 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Target discovery of selective non-small-cell lung cancer toxins reveals inhibitors of mitochondrial complex i

Madhusudhan, N., Hu, B., Mishra, P., Calva-Moreno, J. F., Patel, K., Boriack, R., Ready, J. M. & Nijhawan, D., Jan 17 2020, In : ACS chemical biology. 15, 1, p. 158-170 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Liu, Y., Nguyen, P. T., Wang, X., Zhao, Y., Meacham, C. E., Zou, Z., Bordieanu, B., Johanns, M., Vertommen, D., Wijshake, T., May, H., Xiao, G., Shoji-Kawata, S., Rider, M. H., Morrison, S. J., Mishra, P. & Levine, B., Feb 27 2020, In : Nature. 578, 7796, p. 605-609 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Vascularized human cortical organoids (vOrganoids) model cortical development in vivo

Shi, Y., Sun, L., Wang, M., Liu, J., Zhong, S., Li, R., Li, P., Guo, L., Fang, A., Chen, R., Ge, W. P., Wu, Q. & Wang, X., May 2020, In : PLoS biology. 18, 5, e3000705.

Research output: Contribution to journalArticle

Open Access

α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells

Lesner, N. P., Gokhale, A. S., Kota, K., DeBerardinis, R. J. & Mishra, P., Jul 2020, In : Metabolic Engineering. 60, p. 157-167 11 p.

Research output: Contribution to journalArticle

Open Access
2019

Arid1a Loss Drives Nonalcoholic Steatohepatitis in Mice Through Epigenetic Dysregulation of Hepatic Lipogenesis and Fatty Acid Oxidation

Moore, A., Wu, L., Chuang, J. C., Sun, X., Luo, X., Gopal, P., Li, L., Celen, C., Zimmer, M. & Zhu, H., May 2019, In : Hepatology. 69, 5, p. 1931-1945 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Blockade of MCU-Mediated Ca 2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation

Tomar, D., Jaña, F., Dong, Z., Quinn, W. J., Jadiya, P., Breves, S. L., Daw, C. C., Srikantan, S., Shanmughapriya, S., Nemani, N., Carvalho, E., Tripathi, A., Worth, A. M., Zhang, X., Razmpour, R., Seelam, A., Rhode, S., Mehta, A. V., Murray, M., Slade, D. & 12 others, Ramirez, S. H., Mishra, P., Gerhard, G. S., Caplan, J., Norton, L., Sharma, K., Rajan, S., Balciunas, D., Wijesinghe, D. S., Ahima, R. S., Baur, J. A. & Madesh, M., Mar 26 2019, In : Cell Reports. 26, 13, p. 3709-3725.e7

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2 Scopus citations

Evaluation of l-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of Cancer

Xin, Y., Gao, X., Liu, L., Ge, W. P., Jain, M. K. & Cai, H., Dec 1 2019, In : Molecular Imaging and Biology. 21, 6, p. 1138-1146 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

Ni, M., Solmonson, A., Pan, C., Yang, C., Li, D., Notzon, A., Cai, L., Guevara, G., Zacharias, L. G., Faubert, B., Vu, H. S., Jiang, L., Ko, B., Morales, N. M., Pei, J., Vale, G., Rakheja, D., Grishin, N. V., McDonald, J. G., Gotway, G. K. & 3 others, McNutt, M. C., Pascual, J. M. & DeBerardinis, R. J., Apr 30 2019, In : Cell Reports. 27, 5, p. 1376-1386.e6

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass

Shen, B., Vardy, K., Hughes, P., Tasdogan, A., Zhao, Z., Yue, R., Crane, G. M. & Morrison, S. J., Jan 11 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Investigation of Postnatal Craniofacial Bone Development with Tissue Clearing-Based Three-Dimensional Imaging

Luo, W., Yi, Y., Jing, D., Zhang, S., Men, Y., Ge, W. P. & Zhao, H., Oct 1 2019, In : Stem Cells and Development. 28, 19, p. 1310-1321 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation

Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., Liu, X., Li, K., Lyu, J., Dickerson, K. E., Chen, W., Ni, M., Merritt, M. E., Morrison, S. J., Skoda, R. C., DeBerardinis, R. J. & 1 others, Xu, J., Sep 1 2019, In : Cancer discovery. 9, 9, p. 1228-1247 20 p.

Research output: Contribution to journalArticle

14 Scopus citations

MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes

Li, M., Tu, S., Li, Z., Tan, F., Liu, J., Wang, Q., Zhang, Y., Xu, J., Zhang, Y., Zhou, F. & Shao, Z., Dec 1 2019, In : Cell Discovery. 5, 1, 40.

Research output: Contribution to journalArticle

Open Access

Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

Choi, E., Kikuchi, S., Gao, H., Brodzik, K., Nassour, I., Yopp, A., Singal, A. G., Zhu, H. & Yu, H., Dec 1 2019, In : Nature communications. 10, 1, 1473.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

Venkateswaran, N., Lafita-Navarro, M. C., Hao, Y. H., Kilgore, J. A., Perez-Castro, L., Braverman, J., Borenstein-Auerbach, N., Kim, M., Lesner, N. P., Mishra, P., Brabletz, T., Shay, J. W., DeBerardinis, R. J., Williams, N. S., Yilmaz, O. H. & Conacci-Sorrell, M., Sep 1 2019, In : Genes and Development. 33, 17-18, p. 1236-1251 16 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte

Udden, S. N., Kwak, Y. T., Godfrey, V., Khan, M. A. W., Khan, S., Loof, N., Peng, L., Zhu, H. & Zaki, H., Apr 2019, In : eLife. 8, e40396.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Phosphorylation of histone H3.3 at serine 31 promotes p300 activity and enhancer acetylation

Martire, S., Gogate, A. A., Whitmill, A., Tafessu, A., Nguyen, J., Teng, Y. C., Tastemel, M. & Banaszynski, L., Jun 1 2019, In : Nature genetics. 51, 6, p. 941-946 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

PUMILIO hyperactivity drives premature aging of norad-deficient mice

Kopp, F., Elguindy, M. M., Yalvac, M. E., Zhang, H., Chen, B., Gillett, F. A., Lee, S., Sivakumar, S., Yu, H., Xie, Y., Mishra, P., Sahenk, Z. & Mendell, J. T., Feb 2019, In : eLife. 8, e42650.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver

Cappel, D. A., Deja, S., Duarte, J. A. G., Kucejova, B., Iñigo, M., Fletcher, J. A., Fu, X., Berglund, E. D., Liu, T., Elmquist, J. K., Hammer, S., Mishra, P., Browning, J. D. & Burgess, S. C., Jun 4 2019, In : Cell Metabolism. 29, 6, p. 1291-1305.e8

Research output: Contribution to journalArticle

9 Scopus citations

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: A multi-center evaluation

Gurumurthy, C. B., O'Brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S. K., Beauchamp, M. C., Becker, K. A., Bernas, G., Brough, D., Carrillo-Salinas, F., Chan, W., Chen, H., Dawson, R., Demambro, V., D'Hont, J., Dibb, K. M., Eudy, J. D. & 93 others, Gan, L., Gao, J., Gonzales, A., Guntur, A. R., Guo, H., Harms, D. W., Harrington, A., Hentges, K. E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N. C., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C. B., Li, L., Lindner, V., Liu, X. D., Lopez-Castejon, G., Loudon, A., Lowe, J., Jerome-Majewska, L. A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y. I., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M. P., Ray, D., Redder, R. J., Rosen, C. J., Ross, N., Ruhe, M. T., Ryzhova, L., Salvador, A. M., Alam, S. S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A. W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B. J., Wright, C. S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D. J., Hochepied, T., Thomas, P., Parker-Thornburg, J., Adamson, A. D., Yoshiki, A., Schmouth, J. F., Golovko, A., Thompson, W. R., Lloyd, K. C. K., Wood, J. A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J. M. & Burgio, G., Aug 26 2019, In : Genome biology. 20, 1, 171.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow

Comazzetto, S., Murphy, M. M., Berto, S., Jeffery, E., Zhao, Z. & Morrison, S. J., Mar 7 2019, In : Cell Stem Cell. 24, 3, p. 477-486.e6

Research output: Contribution to journalArticle

19 Scopus citations

Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease

Zhu, M., Lu, T., Jia, Y., Luo, X., Gopal, P., Li, L., Odewole, M., Renteria, V., Singal, A. G., Jang, Y., Ge, K., Wang, S. C., Sorouri, M., Parekh, J. R., MacConmara, M. P., Yopp, A. C., Wang, T. & Zhu, H., Apr 18 2019, In : Cell. 177, 3, p. 608-621.e12

Research output: Contribution to journalArticle

25 Scopus citations

SWI/SNF component ARID1A restrains pancreatic neoplasia formation

Wang, S. C., Nassour, I., Xiao, S., Zhang, S., Luo, X., Lee, J., Li, L., Sun, X., Nguyen, L. H., Chuang, J. C., Peng, L., Daigle, S., Shen, J. & Zhu, H., Jul 1 2019, In : Gut. 68, 7, p. 1259-1270 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

The Circadian Protein Nocturnin Regulates Metabolic Adaptation in Brown Adipose Tissue

Onder, Y., Laothamatas, I., Berto, S., Sewart, K., Kilaru, G., Bordieanu, B., Stubblefield, J. J., Konopka, G., Mishra, P. & Green, C. B., Sep 27 2019, In : iScience. 19, p. 83-92 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The ubiquitin ligase UBE3B, disrupted in intellectual disability and absent speech, regulates metabolic pathways by targeting BCKDK

Cheon, S., Kaur, K., Nijem, N., Tuncay, I. O., Kumar, P., Dean, M., Juusola, J., Guillen-Sacoto, M. J., Bedoukian, E., Ierardi-Curto, L., Kaplan, P., Bradley Schaefer, G., Mishra, P. & Chahrour, M. H., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3662-3667 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling

Kasitinon, S. Y., Eskiocak, U., Martin, M., Bezwada, D., Khivansara, V., Tasdogan, A., Zhao, Z., Mathews, T., Aurora, A. B. & Morrison, S. J., Aug 27 2019, In : Cell Reports. 28, 9, p. 2293-2305.e9

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9

Liu, X., Zhang, Y., Chen, Y., Li, M., Shao, Z., Zhang, M. Q. & Xu, J., Jul 2018, In : Current Protocols in Molecular Biology. 123, 1, e64.

Research output: Contribution to journalArticle

3 Scopus citations

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Liu, N., Hargreaves, V. V., Zhu, Q., Kurland, J. V., Hong, J., Kim, W., Sher, F., Macias-Trevino, C., Rogers, J. M., Kurita, R., Nakamura, Y., Yuan, G. C., Bauer, D. E., Xu, J., Bulyk, M. L. & Orkin, S. H., Apr 5 2018, In : Cell. 173, 2, p. 430-442.e17

Research output: Contribution to journalArticle

59 Scopus citations

Dissecting super-enhancer hierarchy based on chromatin interactions

Huang, J., Li, K., Cai, W., Liu, X., Zhang, Y., Orkin, S. H., Xu, J. & Yuan, G. C., Dec 1 2018, In : Nature communications. 9, 1, 943.

Research output: Contribution to journalArticle

40 Scopus citations

Gain-of-function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities

Rodan, L. H., Anyane-Yeboa, K., Chong, K., Klein Wassink-Ruiter, J. S., Wilson, A., Smith, L., Kothare, S. V., Rajabi, F., Blaser, S., Ni, M., DeBerardinis, R. J., Poduri, A. & Berry, G. T., Jan 1 2018, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

4 Scopus citations

GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism

Tanimura, N., Liao, R., Wilson, G. M., Dent, M. R., Cao, M., Burstyn, J. N., Hematti, P., Liu, X., Zhang, Y., Zheng, Y., Keles, S., Xu, J., Coon, J. J. & Bresnick, E. H., Sep 10 2018, In : Developmental cell. 46, 5, p. 581-594.e4

Research output: Contribution to journalArticle

3 Scopus citations

Histone variant H3.3–mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos

Kong, Q., Banaszynski, L. A., Geng, F., Zhang, X., Zhang, J., Zhang, H., O’Neill, C. L., Yan, P., Liu, Z., Shido, K., Palermo, G. D., David Allis, C., Rafii, S., Rosenwaks, Z. & Wen, D., Mar 9 2018, In : Journal of Biological Chemistry. 293, 10, p. 3829-3838 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

Huang, F., Ni, M., Chalishazar, M. D., Huffman, K. E., Kim, J., Cai, L., Shi, X., Cai, F., Zacharias, L. G., Ireland, A. S., Li, K., Gu, W., Kaushik, A. K., Liu, X., Gazdar, A. F., Oliver, T. G., Minna, J. D., Hu, Z. & DeBerardinis, R. J., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

26 Scopus citations

Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration

Zhang, S., Nguyen, L. H., Zhou, K., Tu, H. C., Sehgal, A., Nassour, I., Li, L., Gopal, P., Goodman, J., Singal, A. G., Yopp, A., Zhang, Y., Siegwart, D. J. & Zhu, H., Apr 1 2018, In : Gastroenterology. 154, 5, p. 1421-1434 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress

Nemani, N., Carvalho, E., Tomar, D., Dong, Z., Ketschek, A., Breves, S. L., Jaña, F., Worth, A. M., Heffler, J., Palaniappan, P., Tripathi, A., Subbiah, R., Riitano, M. F., Seelam, A., Manfred, T., Itoh, K., Meng, S., Sesaki, H., Craigen, W. J., Rajan, S. & 9 others, Shanmughapriya, S., Caplan, J., Prosser, B. L., Gill, D. L., Stathopulos, P. B., Gallo, G., Chan, D. C., Mishra, P. & Madesh, M., Apr 24 2018, In : Cell Reports. 23, 4, p. 1005-1019 15 p.

Research output: Contribution to journalArticle

17 Scopus citations

Regulation of embryonic haematopoietic multipotency by EZH1

Vo, L. T., Kinney, M. A., Liu, X., Zhang, Y., Barragan, J., Sousa, P. M., Jha, D. K., Han, A., Cesana, M., Shao, Z., North, T. E., Orkin, S. H., Doulatov, S., Xu, J. & Daley, G. Q., Jan 25 2018, In : Nature. 553, 7689, p. 506-510 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

The Polyploid State Plays a Tumor-Suppressive Role in the Liver

Zhang, S., Zhou, K., Luo, X., Li, L., Tu, H. C., Sehgal, A., Nguyen, L. H., Zhang, Y., Gopal, P., Tarlow, B. D., Siegwart, D. J. & Zhu, H., Jan 1 2018, (Accepted/In press) In : Developmental Cell.

Research output: Contribution to journalArticle

33 Scopus citations

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Updegraff, B. L., Zhou, X., Guo, Y., Padanad, M. S., Chen, P. H., Yang, C., Sudderth, J., Rodriguez-Tirado, C., Girard, L., Minna, J. D., Mishra, P., DeBerardinis, R. J. & O'Donnell-Mendell, K. A., Jan 1 2018, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

5 Scopus citations
2017
10 Scopus citations

Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer

Sun, X., Wang, S. C., Wei, Y., Luo, X., Jia, Y., Li, L., Gopal, P., Zhu, M., Nassour, I., Chuang, J. C., Maples, T., Celen, C., Nguyen, L. H., Wu, L., Fu, S., Li, W., Hui, L., Tian, F., Ji, Y., Zhang, S. & 8 others, Sorouri, M., Hwang, T. H., Letzig, L., James, L., Wang, Z., Yopp, A. C., Singal, A. G. & Zhu, H., Nov 13 2017, In : Cancer Cell. 32, 5, p. 574-589.e6

Research output: Contribution to journalArticle

40 Scopus citations

Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment

Celen, C., Chuang, J. C., Luo, X., Nijem, N., Walker, A. K., Chen, F., Zhang, S., Chung, A. S., Nguyen, L. H., Nassour, I., Budhipramono, A., Sun, X., Bok, L. A., McEntagart, M., Gevers, E. F., Birnbaum, S. G., Eisch, A. J., Powell, C. M., Ge, W. P., Santen, G. W. E. & 2 others, Chahrour, M. & Zhu, H., Jul 11 2017, In : eLife. 6, e25730.

Research output: Contribution to journalArticle

22 Scopus citations

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Agathocleous, M., Meacham, C. E., Burgess, R. J., Piskounova, E., Zhao, Z., Crane, G. M., Cowin, B. L., Bruner, E., Murphy, M. M., Chen, W., Spangrude, G. J., Hu, Z., DeBerardinis, R. J. & Morrison, S. J., Sep 28 2017, In : Nature. 549, 7673, p. 476-481 6 p.

Research output: Contribution to journalArticle

136 Scopus citations