Eugene Mcdermott Center For Human Growth & Development

Research Output

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Comment/debate
2020

Author Correction: Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition (Scientific Reports, (2019), 9, 1, (2106), 10.1038/s41598-019-38683-8)

Bhattacharyya, S., Duan, J., Wang, L., Li, B., Bhakta, M., Fernandez-Perez, A., Hon, G. C. & Munshi, N. V., Dec 1 2020, In : Scientific reports. 10, 1, 4069.

Research output: Contribution to journalComment/debate

Open Access

Leveraging insights into cancer metabolism—a symposium report

Cable, J., Finley, L., Tu, B. P., Patti, G. J., Oliver, T. G., Vardhana, S., Mana, M., Ericksen, R., Khare, S., DeBerardinis, R., Stockwell, B. R., Edinger, A., Haigis, M. & Kaelin, W., Jan 1 2020, In : Annals of the New York Academy of Sciences. 1462, 1, p. 5-13 9 p.

Research output: Contribution to journalComment/debate

We need to talk about the Warburg effect

DeBerardinis, R. J. & Chandel, N. S., Feb 1 2020, In : Nature Metabolism. 2, 2, p. 127-129 3 p.

Research output: Contribution to journalComment/debate

Open Access
9 Scopus citations
2019

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access

Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division

Greaves, R. F., Bernardini, S., Ferrari, M., Fortina, P., Gouget, B., Gruson, D., Lang, T., Loh, T. P., Morris, H. A., Park, J. Y., Roessler, M., Yin, P. & Kricka, L. J., Aug 2019, In : Clinica Chimica Acta. 495, p. 570-589 20 p.

Research output: Contribution to journalComment/debate

5 Scopus citations

Metabolic vulnerability in tumours illuminated

Rao, A. D. & DeBerardinis, R. J., Nov 1 2019, In : Nature. 575, 7782, p. 296-297 2 p.

Research output: Contribution to journalComment/debate

Open Access
2018

Correction: Kinome-wide RNA interference screen reveals a role for PDK1 in acquired resistance to CDK4/6 inhibition in ER-positive breast cancer (Cancer Research (2017) 77 (2488-2499) DOI: 10.1158/0008-5472)

Jansen, V. M., Bhola, N. E., Bauer, J. A., Formisano, L., Lee, K. M., Hutchinson, K. E., Witkiewicz, A. K., Moore, P. D., Estrada, M. V., Sánchez, V., Ericsson, P. G., Sanders, M. E., Pohlmann, P. R., Pishvaian, M. J., Riddle, D. A., Dugger, T. C., Wei, W., Knudsen, E. & Arteaga, C. L., Feb 15 2018, In : Cancer Research. 79, 4, 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Erratum: Correction: SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer (PLoS genetics (2017) 13 3 (e1006650))

Suresh, S., Durakoglugil, D., Zhou, X., Zhu, B., Comerford, S. A., Xing, C., Xie, X. J., York, B. & O'Donnell, K. A., Apr 1 2018, In : PLoS genetics. 14, 4, p. e1007344

Research output: Contribution to journalComment/debate

Open Access

Retraction: Overexpression of proteins HMGA1 induces cell cycle deregulation and apoptosis in normal rat thyroid cells (Cancer Research (2001) 61 (4583–4590))

Fedele, M., Pierantoni, G. M., Berlingieri, M. T., Battista, S., Baldassarre, G., Munshi, N., Dentice, M., Thanos, D., Santoro, M., Viglietto, G. & Fusco, A., Dec 15 2018, In : Cancer research. 78, 24, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2017

Patient privacy and clinical laboratory data

Park, J. Y., Cornish, T. C., Hogarth, M., Jackson, B. R. & Rosati, K. B., Aug 1 2017, In : Clinical Chemistry. 63, 8, p. 1321-1325 5 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2016

Blocking fatty acid synthesis reduces lung tumor growth in mice

Kim, J. & Deberardinis, R. J., Oct 6 2016, In : Nature Medicine. 22, 10, p. 1077-1078 2 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer (Nat. Genet. (2015) 47 (1475-1481))

Denicola, G. M., Chen, P. H., Mullarky, E., Sudderth, J. A., Hu, Z., Wu, D., Tang, H., Xie, Y., Asara, J. M., Huffman, K. E., Wistuba, I. I., Minna, J. D., Deberardinis, R. J. & Cantley, L. C., Mar 29 2016, In : Nature genetics. 48, 4, 1 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Erratum: Global diversity in the TAS2R38 bitter taste receptor: Revisiting a classic evolutionary PROPosal (Scientific Reports (2016) 6 (25506) DOI: 10.1038/srep25506)

Risso, D. S., Mezzavilla, M., Pagani, L., Robino, A., Morini, G., Tofanelli, S., Carrai, M., Campa, D., Barale, R., Caradonna, F., Gasparini, P., Luiselli, D., Wooding, S. & Drayna, D., Jun 27 2016, In : Scientific Reports. 6, 28406.

Research output: Contribution to journalComment/debate

Targeting Disease through Metabolism

Green, D., DeBerardinis, R. & Febbraio, M., Jun 16 2016, In : Cell. 165, 7, p. 1561-1562 2 p.

Research output: Contribution to journalComment/debate

2015

Case 1: Progressive lethargy in a 4-Day-Old term infant

Weydig, H. M., Veltkamp, D., Kakkilaya, V., Stumpf, K., Waber, L. J. & Brion, L. P., Nov 2015, In : NeoReviews. 16, 11, p. e642-e644

Research output: Contribution to journalComment/debate

Erratum: Asfotase-αimproves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1 (Nature Medicine (2014) 20 (904-910) DOI: 10.1038/nm.3583)

De La Croix Ndong, J., Makowski, A. J., Uppuganti, S., Vignaux, G., Ono, K., Perrien, D. S., Joubert, S., Baglio, S. R., Granchi, D., Stevenson, D. A., Rios, J. J., Nyman, J. S. & Elefteriou, F., Apr 1 2015, In : Nature medicine. 21, 4, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

The cancer cell ‘energy grid’: TGF-β1 signaling coordinates metabolism for migration

Jiang, L., Deberardinis, R. & Boothman, D. A., Jul 3 2015, In : Molecular and Cellular Oncology. 2, 3, e981994.

Research output: Contribution to journalComment/debate

12 Scopus citations
2014

Erratum: A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation (Current Biology (2014) 24 (2327-2334))

Chen, C. T., Hehnly, H., Yu, Q., Farkas, D., Zheng, G., Redick, S. D., Hung, H. F., Samtani, R., Jurczyk, A., Akbarian, S., Wise, C., Jackson, A., Bober, M., Guo, Y., Lo, C. & Doxsey, S., Dec 15 2014, In : Current Biology. 24, 24, 1 p.

Research output: Contribution to journalComment/debate

Erratum: A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation (Current Biology (2014) 24 (2327-2334))

Chen, C. T., Hehnly, H., Yu, Q., Farkas, D., Zheng, G., Redick, S. D., Hung, H. F., Samtani, R., Jurczyk, A., Akbarian, S., Wise, C., Jackson, A., Bober, M., Guo, Y., Lo, C. & Doxsey, S., Oct 6 2014, In : Current Biology. 24, 19, 1 p.

Research output: Contribution to journalComment/debate

2013

A comparison of the likelihood ratio test and the variance-stabilising transformation-based tests for detecting association of rare variants

Xing, G., Ku, H. C. & Xing, C., Mar 18 2013, In : Annals of Human Genetics. 77, 4, p. 333-335 3 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis (Nature Genetics (2013) 45 (613-620))

Fingerlin, T. E., Murphy, E., Zhang, W., Peljto, A. L., Brown, K. K., Steele, M. P., Loyd, J. E., Cosgrove, G. P., Lynch, D., Groshong, S., Collard, H. R., Wolters, P. J., Bradford, W. Z., Kossen, K., Seiwert, S. D., Du Bois, R. M., Garcia, C. K., Devine, M. S., Gudmundsson, G., Isaksson, H. J. & 30 others, Kaminski, N., Zhang, Y., Gibson, K. F., Lancaster, L. H., Cogan, J. D., Mason, W. R., Maher, T. M., Molyneaux, P. L., Wells, A. U., Moffatt, M. F., Selman, M., Pardo, A., Kim, D. S., Crapo, J. D., Make, B. J., Regan, E. A., Walek, D. S., Daniel, J. J., Kamatani, Y., Zelenika, D., Smith, K., Mckean, D., Pedersen, B. S., Talbert, J., Kidd, R. N., Markin, C. R., Beckman, K. B., Lathrop, M., Schwarz, M. I. & Schwartz, D. A., Nov 1 2013, In : Nature genetics. 45, 11, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Next-generation sequencing in the clinic

Park, J. Y., Kricka, L. J. & Fortina, P., Nov 1 2013, In : Nature biotechnology. 31, 11, p. 990-992 3 p.

Research output: Contribution to journalComment/debate

29 Scopus citations

The Proto-oncometabolite Fumarate Binds Glutathione to amplify ROS-dependent signaling

Sullivan, L., Martinez-Garcia, E., Nguyen, H., Mullen, A., Dufour, E., Sudarshan, S., Licht, J., Deberardinis, R. & Chandel, N., Jul 25 2013, In : Molecular cell. 51, 2, 1 p.

Research output: Contribution to journalComment/debate

40 Scopus citations
2012

Cancer metabolism: When more is less

Jiang, L. & Deberardinis, R. J., Sep 27 2012, In : Nature. 489, 7417, p. 511-512 2 p.

Research output: Contribution to journalComment/debate

14 Scopus citations

Erratum: The hypoxic epicardial and subepicardial microenvironment (J. of Cardiovasc. Trans. Res. DOI 10.1007/s12265-012-9366-7)

Kocabas, F., Mahmoud, A. I., Sosic, D., Porrello, E. R., Chen, R., Garcia, J. A., Deberardinis, R. J. & Sadek, H. A., Oct 1 2012, In : Journal of cardiovascular translational research. 5, 5, 1 p.

Research output: Contribution to journalComment/debate

Erratum: Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo (Cell Metabolism (2012) 16 (394-406))

Marin-Valencia, I., Yang, C., Mashimo, T., Cho, S., Baek, H., Yang, X. L., Rajagopalan, K. N., Maddie, M., Vemireddy, V., Zhao, Z., Cai, L., Good, L., Tu, B. P., Hatanpaa, K. J., Mickey, B. E., Matés, J. M., Pascual, J. M., Maher, E. A., Malloy, C. R., DeBerardinis, R. J. & 1 others, Bachoo, R. M., Nov 7 2012, In : Cell Metabolism. 16, 5, 1 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Erratum: Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development (European Journal of Human Genetics (2011) DOI: 10.1038/ejhg.2010.245)

Bhoj, E. J., Ramos, P., Baker, L. A., Garg, V., Cost, N., Nordenskjöld, A., Elder, F. F., Bleyl, S. B., Bowles, N. E., Arrington, C. B., Delhomme, B., Vanhoutteghem, A., Djian, P. & Zinn, A. R., Feb 1 2012, In : European Journal of Human Genetics. 20, 2, 1 p.

Research output: Contribution to journalComment/debate

Unsuspected stroke signals: From extravascular blood to vessel lumen

Pascual, J. M., Apr 11 2012, In : Neuroscience Letters. 514, 1, 1 p.

Research output: Contribution to journalComment/debate

2011

Animal models of the human mind: Is there anything like being autistic?

Pascual, J. M., Nov 14 2011, In : Neuroscience Letters. 505, 2, p. 59-60 2 p.

Research output: Contribution to journalComment/debate

Editorial comment

Baker, L., Jun 1 2011, In : Journal of Urology. 185, 6 SUPPL., p. 2472-2473 2 p.

Research output: Contribution to journalComment/debate

Indices of cholesterol metabolism and relative responsiveness to ezetimibe and simvastatin (Journal of Clinical Endocrinology and Metabolism (2010) 95, (800-809))

Lakoski, S. G., Xu, F., Vega, G. L., Grundy, S. M., Chandalia, M., Lam, C., Lowe, R. S., Stepanavage, M. E., Musliner, T. A., Cohen, J. C. & Hobbs, H. H., May 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 5, 1 p.

Research output: Contribution to journalComment/debate

RB pathway and therapeutic sensitivity: New insights in breast cancer and Tamoxifen therapy

Witkiewicz, A. K. & Knudsen, E. S., May 15 2011, In : Cell Cycle. 10, 10, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Synaptic transporters are deceived if they think themselves free

Pascual, J. M., Jan 3 2011, In : Neuroscience Letters. 487, 1, p. 1-2 2 p.

Research output: Contribution to journalComment/debate

2010

CXCR4 signaling identifies a role for IFT2 in ER-negative breast cancers

Brody, J. R. & Witkiewicz, A. K., Sep 15 2010, In : Cancer Biology and Therapy. 10, 6, p. 615-616 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Erratum: Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy (Journal of Clinical Investigation (2010) 120, 3 (791-802) DOI: 10.1172/JCI40076)

O'Toole, J. F., Liu, Y., Davis, E. E., Westlake, C. J., Attanasio, M., Otto, E. A., Seelow, D., Nurnberg, G., Becker, C., Nuutinen, M., Kärppä, M., Ignatius, J., Uusimaa, J., Pakanen, S., Jaakkola, E., Van Den Heuvel, L. P., Fehrenbach, H., Wiggins, R., Zhou, W., Wolf, M. T. F. & 34 others, Wise, E., Helou, J., Allen, S. J., Murga-Zamalloa, C. A., Ashraf, S., Chaki, M., Heeringa, S., Chernin, G., Hoskins, B. E., Chaib, H., Gleeson, J., Kusakabe, T., Suzuki, T., Isaac, R. E., Quarmby, L. M., Tennant, B., Fujioka, H., Tuominen, H., Hassinen, I., Lohi, H., Van Houten, J. L., Rotig, A., Sayer, J. A., Rolinski, B., Freisinger, P., Madhavan, S. M., Herzer, M., Madignier, F., Prokisch, H., Nurnberg, P., Jackson, P. K., Khanna, H., Katsanis, N. & Hildebrandt, F., Apr 1 2010, In : Journal of Clinical Investigation. 120, 4, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Research Highlights: Backtracking on CYP2C19 genotyping in clopidogrel therapy?

Park, J., Dec 1 2010, In : Biomarkers in Medicine. 4, 6, 1 p.

Research output: Contribution to journalComment/debate

The tragedy of the microarray anticommons

Park, J. Y., Nov 1 2010, In : Clinical chemistry. 56, 11, p. 1683-1685 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2009

Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade (The Journal of Experimental Medicine (2007), 204, 9, (2131-2144))

Allantaz, F., Chaussabel, D., Stichweh, D., Bennett, L., Allman, W., Mejias, A., Ardura, M., Chung, W., Smith, E., Wise, C., Palucka, K., Ramilo, O., Punaro, M., Banchereau, J. & Pascual, V., Sep 28 2009, In : Journal of Experimental Medicine. 206, 10, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Preventing misfolded neuronal protein aggregation by molecular diplomacy

Pascual, J. M., Jan 9 2009, In : Neuroscience Letters. 449, 2, p. 85-86 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Response to the comment by J. Ross

Barber, T. D., Wickiser, J. E., Wilcox, D. T. & Baker, L. A., Oct 1 2009, In : Journal of Pediatric Urology. 5, 5, 1 p.

Research output: Contribution to journalComment/debate

2008

Erratum: BAC TransgeneOmics: A high-throughput method for exploration of protein function in mammals (Nature Methods (2008) vol. 5 (409-415))

Poser, I., Sarov, M., Hutchins, J. R. A., Hériché, J. K., Toyoda, Y., Pozniakovsky, A., Weigl, D., Nitzsche, A., Hegemann, B., Bird, A. W., Pelletier, L., Kittler, R., Hua, S., Naumann, R., Augsburg, M., Sykora, M. M., Hofemeister, H., Zhang, Y., Nasmyth, K., White, K. P. & 7 others, Dietzel, S., Mechtler, K., Durbin, R., Stewart, A. F., Peters, J. M., Buchholz, F. & Hyman, A. A., Aug 1 2008, In : Nature methods. 5, 8, 1 p.

Research output: Contribution to journalComment/debate

2005

Erratum: Low LDL cholesterol in African Americans resulting from frequent nonsense mutations in PCSK9 (Nature Genetics (2005) 37 (161-165))

Cohen, J., Pertsemlidis, A., Kotowski, I. K., Graham, R., Garcia, C. K. & Hobbs, H. H., Jan 1 2005, In : Nature genetics. 37, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations
2004

Erratum: Molecular evolution of Pediculus humanus and the origin of clothing (Current Biology 13:16 (pp. 1414-1417))

Kittler, R., Kayser, M. & Stoneking, M., Dec 29 2004, In : Current Biology. 14, 24, 1 p.

Research output: Contribution to journalComment/debate

23 Scopus citations

Erratum: Inherited interstitial lung disease (Clinics in Chest Medicine (2004) 25:3 (421-433) PII: S0272-5231(04)00054-1 and DOI: 10.1016/j.ccm.2004.05. 001)

Garcia, C. K. & Raghu, G., Dec 1 2004, In : Clinics in Chest Medicine. 25, 4 SPEC.ISS., p. xi

Research output: Contribution to journalComment/debate

Fever, molecular excitability and epilepsy

Pascual, J. M., Sep 16 2004, In : Neuroscience Letters. 368, 1, 1 p.

Research output: Contribution to journalComment/debate

2003

Endothelial lipase: Direct evidence for a role in HDL metabolism

Cohen, J. C., Feb 1 2003, In : Journal of Clinical Investigation. 111, 3, p. 318-321 4 p.

Research output: Contribution to journalComment/debate

26 Scopus citations