Eugene Mcdermott Center For Human Growth & Development

Research Output

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Review article
2020

Genetic Risk Factors and Disease Modifiers of Nonalcoholic Steatohepatitis

Kozlitina, J., Mar 2020, In : Gastroenterology Clinics of North America. 49, 1, p. 25-44 20 p.

Research output: Contribution to journalReview article

Metabolic reprogramming and cancer progression

Faubert, B., Solmonson, A. & DeBerardinis, R. J., Apr 10 2020, In : Science. 368, 6487, eaaw5473.

Research output: Contribution to journalReview article

The cartilage matrisome in adolescent idiopathic scoliosis

Wise, C. A., Sepich, D., Ushiki, A., Khanshour, A. M., Kidane, Y. H., Makki, N., Gurnett, C. A., Gray, R. S., Rios, J. J., Ahituv, N. & Solnica-Krezel, L., Dec 1 2020, In : Bone Research. 8, 1, 13.

Research output: Contribution to journalReview article

Open Access
2019

Genomic testing in pediatric epilepsy

Thodeson, D. M. & Park, J. Y., Jan 1 2019, In : Cold Spring Harbor Molecular Case Studies. 5, 4

Research output: Contribution to journalReview article

Open Access

Mechanisms and Implications of Metabolic Heterogeneity in Cancer

Kim, J. & DeBerardinis, R. J., Sep 3 2019, In : Cell Metabolism. 30, 3, p. 434-446 13 p.

Research output: Contribution to journalReview article

10 Scopus citations
2018

2018 association of American physicians George M. Kober lecture science, serendipity, and the single degree

Hobbs, H. H., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4218-4223 6 p.

Research output: Contribution to journalReview article

Genomic privacy

Schwab, A. P., Luu, H. S., Wang, J. & Park, J. Y., Dec 1 2018, In : Clinical Chemistry. 64, 12, p. 1696-1703 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Lipoic acid metabolism and mitochondrial redox regulation

Solmonson, A. & DeBerardinis, R. J., May 18 2018, In : Journal of Biological Chemistry. 293, 20, p. 7522-7530 9 p.

Research output: Contribution to journalReview article

31 Scopus citations

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

Fischer, G. M., Vashisht Gopal, Y. N., McQuade, J. L., Peng, W., DeBerardinis, R. J. & Davies, M. A., Jan 2018, In : Pigment Cell and Melanoma Research. 31, 1, p. 11-30 20 p.

Research output: Contribution to journalReview article

28 Scopus citations

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

679 Scopus citations
2017

Medical and dietary interventions for preventing recurrent urinary stones in children

Kern, A., Grimsby, G., Mayo, H. & Baker, L. A., Nov 9 2017, In : Cochrane Database of Systematic Reviews. 2017, 11, CD011252.

Research output: Contribution to journalReview article

10 Scopus citations

Nanostructured luminescently labeled nucleic acids

Kricka, L. J., Fortina, P. & Park, J. Y., Mar 1 2017, In : Luminescence. 32, 2, p. 132-141 10 p.

Research output: Contribution to journalReview article

2 Scopus citations

The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies

Knudsen, E. S. & Witkiewicz, A. K., Jan 1 2017, In : Trends in Cancer. 3, 1, p. 39-55 17 p.

Research output: Contribution to journalReview article

61 Scopus citations

Understanding the Intersections between Metabolism and Cancer Biology

Vander Heiden, M. G. & DeBerardinis, R. J., Feb 9 2017, In : Cell. 168, 4, p. 657-669 13 p.

Research output: Contribution to journalReview article

421 Scopus citations
2016

Fundamentals of cancer metabolism

DeBerardinis, R. J. & Chandel, N. S., May 1 2016, In : Science advances. 2, 5, p. e1600200

Research output: Contribution to journalReview article

521 Scopus citations

Pulmonary fibrosis in the era of stratified medicine

Mathai, S. K., Newton, C. A., Schwartz, D. A. & Garcia, C. K., Dec 1 2016, In : Thorax. 71, 12, p. 1154-1160 7 p.

Research output: Contribution to journalReview article

21 Scopus citations

Review article: The global emergence of Helicobacter pylori antibiotic resistance

Thung, I., Aramin, H., Vavinskaya, V., Gupta, S., Park, J. Y., Crowe, S. E. & Valasek, M. A., Feb 1 2016, In : Alimentary Pharmacology and Therapeutics. 43, 4, p. 514-533 20 p.

Research output: Contribution to journalReview article

228 Scopus citations
2015

A roadmap for interpreting 13C metabolite labeling patterns from cells

Buescher, J. M., Antoniewicz, M. R., Boros, L. G., Burgess, S. C., Brunengraber, H., Clish, C. B., DeBerardinis, R. J., Feron, O., Frezza, C., Ghesquiere, B., Gottlieb, E., Hiller, K., Jones, R. G., Kamphorst, J. J., Kibbey, R. G., Kimmelman, A. C., Locasale, J. W., Lunt, S. Y., Maddocks, O. D. K., Malloy, C. & 17 others, Metallo, C. M., Meuillet, E. J., Munger, J., Nöh, K., Rabinowitz, J. D., Ralser, M., Sauer, U., Stephanopoulos, G., St-Pierre, J., Tennant, D. A., Wittmann, C., Vander Heiden, M. G., Vazquez, A., Vousden, K., Young, J. D., Zamboni, N. & Fendt, S. M., Aug 1 2015, In : Current Opinion in Biotechnology. 34, p. 189-201 13 p.

Research output: Contribution to journalReview article

239 Scopus citations

Designing a broad-spectrum integrative approach for cancer prevention and treatment

Block, K. I., Gyllenhaal, C., Lowe, L., Amedei, A., Ruhul Amin, A. R. M., Amin, A., Aquilano, K., Arbiser, J., Arreola, A., Arzumanyan, A., Salman Ashraf, S., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A., Bishayee, A., Blain, S. W., Block, P. B., Boosani, C. S., Carey, T. E. & 160 others, Carnero, A., Carotenuto, M., Casey, S. C., Chakrabarti, M., Chaturvedi, R., Chen, G. Z., Chen, H., Chen, S., Chen, Y. C., Choi, B. K., Ciriolo, M. R., Coley, H. M., Collins, A. R., Connell, M., Crawford, S., Curran, C. S., Dabrosin, C., Damia, G., Dasgupta, S., DeBerardinis, R. J., Decker, W. K., Dhawan, P., Diehl, A. M. E., Dong, J. T., Dou, Q. P., Drewa, J. E., Elkord, E., El-Rayes, B., Feitelson, M. A., Felsheru, D. W., Ferguson, L. R., Fimognari, C., Firestone, G. L., Frezza, C., Fujii, H., Fuster, M. M., Generali, D., Georgakilas, A. G., Gieseler, F., Gilbertson, M., Green, M. F., Grue, B., Guhal, G., Halicka, D., Helferich, W. G., Heneberg, P., Hentosh, P., Hirschey, M. D., Hofseth, L. J., Holcombe, R. F., Honoki, K., Hsu, H. Y., Huang, G. S., Jensen, L. D., Jiang, W. G., Jones, L. W., Karpowicz, P. A., Keith, W. N., Kerkar, S. P., Khan, G. N., Khatami, M., Ko, Y. H., Kucuk, O., Kulathinal, R. J., Kumar, N. B., Kwon, B. S., Leb, A., Leab, M. A., Lee, H. Y., Lichtor, T., Lin, L. T., Locasale, J. W., Lokeshwar, B. L., Longo, V. D., Lyssiotis, C. A., MacKenzie, K. L., Malhotra, M., Marino, M., Martinez-Chantar, M. L., Matheu, A., Maxwellx, C., McDonnell, E., Meeker, A. K., Mehrmohamadi, M., Mehta, K., Michelotti, G. A., Mohammad, R. M., Mohammed, S. I., Morre, D. J., Muqbil, I., Muralidharcq, V., Murphy, M. P., Nagaraju, G. P., Nahta, R., Niccolai, E., Nowsheen, S., Panis, C., Pantano, F., Parslow, V. R., Pawelec, G., Pedersen, P. L., Poore, B., Poudyal, D., Prakash, S., Prince, M., Raffaghello, L., Rathmell, J. C., Rathmell, W. K., Ray, S. K., Reichrath, J., Rezazadeh, S., Ribatti, D., Ricciardiello, L., Robeydf, R. B., Rodierdh, F., Rupasinghe, H. P. V., Russo, G. L., Ryan, E. P., Samadi, A. K., Sanchez-Garcia, I., Sanders, A. J., Santini, D., Sarkar, M., Sasada, T., Saxena, N. K., Shackelford, R. E., Shantha Kumara, H. M. C., Sharma, D., Shin, D. M., Sidransky, D., Siegelin, M. D., Signori, E., Singh, N., Sivanand, S., Sliva, D., Smythe, C., Spagnuolo, C., Stafforini, D. M., Stagg, J., Subbarayan, P. R., Sundin, T., Talib, W. H., Thompson, S. K., Tran, P. T., Ungefroren, H., Vander Heiden, M. G., Venkateswaran, V., Vinay, D. S., Vlachostergios, P. J., Wang, Z., Wellen, K. E., Whelan, R. L., Yang, E. S., Yang, H., Yang, X., Yaswen, P., Yedjou, C., Yin, X., Zhu, J. & Zollo, M., Jan 1 2015, In : Seminars in Cancer Biology. 35, p. S276-S304

Research output: Contribution to journalReview article

136 Scopus citations

Dysregulated metabolism contributes to oncogenesis

Target Validation Team, Dec 1 2015, In : Seminars in Cancer Biology. 35, p. S129-S150

Research output: Contribution to journalReview article

112 Scopus citations

In vivo analysis of lung cancer metabolism: Nothing like the real thing

Hensley, C. T. & De Berardinis, R. J., Feb 2 2015, In : Journal of Clinical Investigation. 125, 2, p. 495-497 3 p.

Research output: Contribution to journalReview article

8 Scopus citations

Metabolic pathways promoting cancer cell survival and growth

Boroughs, L. K. & Deberardinis, R. J., Apr 30 2015, In : Nature cell biology. 17, 4, p. 351-359 9 p.

Research output: Contribution to journalReview article

460 Scopus citations

The evolution and future of point-of-care testing

Kricka, L. J., Park, J. Y., Reiprish, A., Polsky, T. G. & Nardiello, M. H., Jan 1 2015, In : Point of Care. 14, 4, p. 110-115 6 p.

Research output: Contribution to journalReview article

5 Scopus citations

The future of laboratory medicine - A 2014 perspective

Kricka, L. J., Polsky, T. G., Park, J. Y. & Fortina, P., Jan 1 2015, In : Clinica Chimica Acta. 438, p. 284-303 20 p.

Research output: Contribution to journalReview article

19 Scopus citations

The history and future of targeting cyclin-dependent kinases in cancer therapy

Asghar, U., Witkiewicz, A. K., Turner, N. C. & Knudsen, E. S., Jan 1 2015, In : Nature Reviews Drug Discovery. 14, 2, p. 130-146 17 p.

Research output: Contribution to journalReview article

612 Scopus citations
2014

Clinical genomics: When whole genome sequencing is like a whole-body CT scan

Park, J. Y., Kricka, L. J., Clark, P., Londin, E. & Fortina, P., Nov 1 2014, In : Clinical chemistry. 60, 11, p. 1390-1392 3 p.

Research output: Contribution to journalReview article

3 Scopus citations

Genomic test validation for incidental findings

Park, J. Y., Fortina, P. & Kricka, L. J., Feb 1 2014, In : Clinical chemistry. 60, 2, p. 292-293 2 p.

Research output: Contribution to journalReview article

2 Scopus citations

HER2 testing in gastric and gastroesophageal junction adenocarcinomas

Park, J. Y. & Zhang, P. J., Jun 2014, In : Diagnostic Histopathology. 20, 6, p. 247-256 10 p.

Research output: Contribution to journalReview article

Prospects for the commercialization of chemiluminescence-based point-of-care and on-site testing devices

Park, J. Y. & Kricka, L. J., Sep 1 2014, In : Analytical and Bioanalytical Chemistry. 406, 23, p. 5631-5637 7 p.

Research output: Contribution to journalReview article

22 Scopus citations

Retinoblastoma tumor suppressor pathway in breast cancer: Prognosis, precision medicine, and therapeutic interventions

Witkiewicz, A. K. & Knudsen, E. S., May 7 2014, In : Breast Cancer Research. 16, 2, 207.

Research output: Contribution to journalReview article

64 Scopus citations

The use of autologous buccal mucosa grafts in vaginal reconstruction

Grimsby, G. M. & Baker, L. A., Aug 2014, In : Current urology reports. 15, 8, 428.

Research output: Contribution to journalReview article

12 Scopus citations
2013

Contemporary review of testicular torsion: New concepts, emerging technologies and potential therapeutics

Dajusta, D. G., Granberg, C. F., Villanueva, C. & Baker, L. A., Dec 2013, In : Journal of Pediatric Urology. 9, 6 PART A, p. 723-730 8 p.

Research output: Contribution to journalReview article

44 Scopus citations

Glutamine and cancer: Cell biology, physiology, and clinical opportunities

Hensley, C. T., Wasti, A. T. & DeBerardinis, R. J., Sep 3 2013, In : Journal of Clinical Investigation. 123, 9, p. 3678-3684 7 p.

Research output: Contribution to journalReview article

527 Scopus citations

Review of autoimmune metaplastic atrophic gastritis

Park, J. Y., Lam-Himlin, D. & Vemulapalli, R., Feb 1 2013, In : Gastrointestinal endoscopy. 77, 2, p. 284-292 9 p.

Research output: Contribution to journalReview article

29 Scopus citations
5 Scopus citations
2012

Cellular metabolism and disease: What do metabolic outliers teach us?

Deberardinis, R. J. & Thompson, C. B., Mar 16 2012, In : Cell. 148, 6, p. 1132-1144 13 p.

Research output: Contribution to journalReview article

350 Scopus citations

Gene regulatory networks in cardiac conduction system development

Munshi, N. V., May 25 2012, In : Circulation research. 110, 11, p. 1525-1537 13 p.

Research output: Contribution to journalReview article

52 Scopus citations

Genetically-defined metabolic reprogramming in cancer

Mullen, A. R. & DeBerardinis, R. J., Nov 1 2012, In : Trends in Endocrinology and Metabolism. 23, 11, p. 552-559 8 p.

Research output: Contribution to journalReview article

49 Scopus citations

Urolithiasis in Children. Surgical Approach

Granberg, C. F. & Baker, L. A., Aug 2012, In : Pediatric clinics of North America. 59, 4, p. 897-908 12 p.

Research output: Contribution to journalReview article

9 Scopus citations
2011

Acinar cell carcinoma with prominent intraductal growth pattern: Case report and review of the literature

Toll, A. D., Mitchell, D., Yeo, C. J., Hruban, R. H. & Witkiewicz, A. K., Dec 1 2011, In : International Journal of Surgical Pathology. 19, 6, p. 795-799 5 p.

Research output: Contribution to journalReview article

17 Scopus citations

College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysis

Brothman, A. R., Dolan, M. M., Goodman, B. K., Park, J. P., Persons, D. L., Saxe, D. F., Tepperberg, J. H., Tsuchiya, K. D., Van Dyke, D. L., Wilson, K. S., Wolff, D. J. & Theil, K. S., Sep 1 2011, In : Genetics in Medicine. 13, 9, p. 765-769 5 p.

Research output: Contribution to journalReview article

9 Scopus citations

Glutamine: Pleiotropic roles in tumor growth and stress resistance

Shanware, N. P., Mullen, A. R., DeBerardinis, R. J. & Abraham, R. T., Mar 1 2011, In : Journal of Molecular Medicine. 89, 3, p. 229-236 8 p.

Research output: Contribution to journalReview article

109 Scopus citations

Human fatty liver disease: Old questions and new insights

Cohen, J. C., Horton, J. D. & Hobbs, H. H., Jun 24 2011, In : Science. 332, 6037, p. 1519-1523 5 p.

Research output: Contribution to journalReview article

1200 Scopus citations

Natural history of MELAS associated with mitochondrial DNA m.3243A>G genotype

Kaufmann, P., Engelstad, K., Wei, Y., Kulikova, R., Oskoui, M., Sproule, D. M., Battista, V., Koenigsberger, D. Y., Pascual, J. M., Shanske, S., Sano, M., Mao, X., Hirano, M., Shungu, D. C., DiMauro, S. & De Vivo, D. C., Nov 29 2011, In : Neurology. 77, 22, p. 1965-1971 7 p.

Research output: Contribution to journalReview article

75 Scopus citations

Role of glutamine in cancer: Therapeutic and imaging implications

Rajagopalan, K. N. & DeBerardinis, R. J., Jul 1 2011, In : Journal of Nuclear Medicine. 52, 7, p. 1005-1008 4 p.

Research output: Contribution to journalReview article

80 Scopus citations

The genetic components of idiopathic nephrolithiasis

Attanasio, M., Mar 1 2011, In : Pediatric Nephrology. 26, 3, p. 337-346 10 p.

Research output: Contribution to journalReview article

12 Scopus citations

The meaning of p16ink4a expression in tumors: Functional significance, clinical associations and future developments

Witkiewicz, A. K., Knudsen, K. E., Dicker, A. P. & Knudsen, E. S., Aug 1 2011, In : Cell Cycle. 10, 15, p. 2497-2503 7 p.

Research output: Contribution to journalReview article

137 Scopus citations

The Past, Present, and Future of Biomarkers: A Need for Molecular Beacons for the Clinical Management of Pancreatic Cancer

Brody, J. R., Witkiewicz, A. K. & Yeo, C. J., Sep 1 2011, In : Advances in surgery. 45, 1, p. 301-321 21 p.

Research output: Contribution to journalReview article

19 Scopus citations