Research Output

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Onderdonk, A. B., Richardson, J. A., Hammer, R. E. & Taurog, J. D., Dec 1 1998, In : Infection and immunity. 66, 12, p. 6022-6023 2 p.

Research output: Contribution to journalArticle

47 Scopus citations

Correlation of structural and spectroscopic properties of a photosynthetic reaction center

Zinth, W., Knapp, E. W., Fischer, S. F., Kaiser, W., Deisenhofer, J. & Michel, H., Aug 23 1985, In : Chemical Physics Letters. 119, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

53 Scopus citations

Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice

Clouthier, D. E., Hosoda, K., Richardson, J. A., Williams, S. C., Yanagisawa, H., Kuwaki, T., Kumada, M., Hammer, R. E. & Yanagisawai, M., 1998, In : Development. 125, 5, p. 813-824 12 p.

Research output: Contribution to journalArticle

530 Scopus citations

Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs

Tamura, N., Doolittle, L. K., Hammer, R. E., Shelton, J. M., Richardson, J. A. & Garbers, D. L., Dec 7 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 49, p. 17300-17305 6 p.

Research output: Contribution to journalArticle

195 Scopus citations

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex

Xing, C., Zhuang, Y., Xu, T. H., Feng, Z., Zhou, X. E., Chen, M., Wang, L., Meng, X., Xue, Y., Wang, J., Liu, H., McGuire, T. F., Zhao, G., Melcher, K., Zhang, C., Xu, H. E. & Xie, X. Q., Feb 20 2020, In : Cell. 180, 4, p. 645-654.e13

Research output: Contribution to journalArticle

9 Scopus citations

Crystallization and preliminary crystallographic analysis of Escherichia coli DNA photolyase

Park, H. W., Sancar, A. & Deisenhofer, J., Aug 1 1993, In : Journal of Molecular Biology. 231, 4, p. 1122-1125 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Crystallization and preliminary structure of beef heart mitochondrial cytochrome-bc1 complex

Yu, C. A., Xia, J. Z., Kachurin, A. M., Yu, L., Xia, D., Kim, H. & Deisenhofer, J., Jul 18 1996, In : Biochimica et Biophysica Acta - Bioenergetics. 1275, 1-2, p. 47-53 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Crystallization and preliminary X-ray analysis of ferric enterobactin receptor FepA, an integral membrane protein from Escherichia coli

Smith, B. S., Kobe, B., Kurumbail, R., Buchanan, S. K., Venkatramani, L., Van Der Helm, D. & Deisenhofer, J., Jul 1 1998, In : Acta Crystallographica Section D: Biological Crystallography. 54, 4, p. 697-699 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Crystallization and preliminary X‐ray analysis of fructose 6‐phosphate, 2‐kinase:fructose 2,6‐bisphosphatase

Istvan, E. S., Hasemann, C. A., Kurumbail, R. G., Uyeda, K. & Deisenhofer, J., Nov 1995, In : Protein Science. 4, 11, p. 2439-2441 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
14 Scopus citations
Open Access
58 Scopus citations

Crystallization of mitochondrial cytochrome b-c1 complex from gel with or without reduced pressure

Yu, C. A., Xia, D., Deisenhofer, J. & Yu, L., Nov 4 1994, In : Journal of Molecular Biology. 243, 4, p. 802-805 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
1263 Scopus citations
407 Scopus citations

Crystallographic refinement at 2.3 Å resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis

Deisenhofer, J., Epp, O., Sinning, I. & Michel, H., Feb 24 1995, In : Journal of Molecular Biology. 246, 3, p. 429-457 29 p.

Research output: Contribution to journalArticle

543 Scopus citations

Crystallographic structure studies of an IgG molecule and an Fc fragment

Huber, R., Deisenhofer, J., Colman, P. M., Matsushima, M. & Palm, W., Dec 1 1976, In : Nature. 264, 5585, p. 415-420 6 p.

Research output: Contribution to journalArticle

286 Scopus citations

Crystal structure analysis and molecular model of a complex of citrate synthase with oxaloacetate and S-acetonyl-coenzyme A

Wiegand, G., Remington, S., Deisenhofer, J. & Huber, R., Mar 25 1984, In : Journal of Molecular Biology. 174, 1, p. 205-219 15 p.

Research output: Contribution to journalArticle

91 Scopus citations

Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolution

Hasemann, C. A., Ravichandran, K. G., Peterson, J. A. & Deisenhofer, J., Mar 4 1994, In : Journal of Molecular Biology. 236, 4, p. 1169-1185 17 p.

Research output: Contribution to journalArticle

363 Scopus citations

Crystal structure of a T cell receptor Vα11 (AV11S5) domain: New canonical forms for the first and second complementarity determining regions

Machius, M., Cianga, P., Deisenhofer, J. & Ward, E. S., Jul 20 2001, In : Journal of Molecular Biology. 310, 4, p. 689-698 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity

Huang, Y., Baxter, R., Smith, B. S., Partch, C. L., Colbert, C. L. & Deisenhofer, J., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17701-17706 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Crystal structure of DNA photolyase from Escherichia coli

Park, H. W., Kim, S. T., Sancar, A. & Deisenhofer, J., Jan 1 1995, In : Science. 268, 5219, p. 1866-1872 7 p.

Research output: Contribution to journalArticle

453 Scopus citations

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

Ravichandran, K. G., Boddupalli, S. S., Hasemann, C. A., Peterson, J. A. & Deisenhofer, J., Jan 1 1993, In : Science. 261, 5122, p. 731-736 6 p.

Research output: Contribution to journalArticle

881 Scopus citations

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

Kobe, B. & Delsenhofer, J., Jan 1 1993, In : Nature. 366, 6457, p. 751-756 6 p.

Research output: Contribution to journalArticle

513 Scopus citations

Crystal structure of Rab geranylgeranyltransferase at 2.0 Å resolution

Zhang, H., Seabra, M. C. & Deisenhofer, J., Mar 1 2000, In : Structure. 8, 3, p. 241-251 11 p.

Research output: Contribution to journalArticle

94 Scopus citations

Crystal structure of Spot 14, a modulator of fatty acid synthesis

Colbert, C. L., Kim, C. W., Moon, Y. A., Henry, L., Palnitkar, M., McKean, W. B., Fitzgerald, K., Deisenhofer, J., Horton, J. D. & Kwon, H. J., Nov 2 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 44, p. 18820-18825 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Crystal structure of the catalytic portion of human HMG-CoA reductase: Insights into regulation of activity and catalysis

Istvan, E. S., Palnitkar, M., Buchanan, S. K. & Deisenhofer, J., Mar 1 2000, In : EMBO Journal. 19, 5, p. 819-830 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

Xia, D., Yu, C. A., Kim, H., Xia, J. Z., Kachurin, A. M., Zhang, L., Yu, L. & Deisenhofer, J., Jul 4 1997, In : Science. 277, 5322, p. 60-66 7 p.

Research output: Contribution to journalArticle

813 Scopus citations

Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus

Machius, M., Henry, L., Palnitkar, M. & Deisenhofer, J., Oct 12 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 21, p. 11717-11722 6 p.

Research output: Contribution to journalArticle

90 Scopus citations

Crystal structure of the formin mDIA1 in autoinhibited conformation

Otomo, T., Tomchick, D. R., Otomo, C., Machius, M. & Rosen, M. K., Nov 1 2010, In : PloS one. 5, 9, p. 1-13 13 p., e12896.

Research output: Contribution to journalArticle

29 Scopus citations

Crystal structure of the human sterol transporter ABCG5/ABCG8

Lee, J. Y., Kinch, L. N., Borek, D. M., Wang, J., Wang, J., Urbatsch, I. L., Xie, X. S., Grishin, N. V., Cohen, J. C., Otwinowski, Z., Hobbs, H. H. & Rosenbaum, D. M., May 4 2016, In : Nature. 533, 7604, p. 561-564 4 p.

Research output: Contribution to journalArticle

114 Scopus citations

Crystal structure of the MHC class Ib molecule H2-M3

Wang, C. R., Fischer Lindahl, K. & Deisenhofer, J., Jan 1 1996, In : Research in Immunology. 147, 5, p. 313-321 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Crystal structure of the outer membrane active transporter FepA from Escherichia coli

Buchanan, S. K., Smith, B. S., Venkatramani, L., Xia, D., Esser, L., Palnitkar, M., Chakraborty, R., Van Der Helm, D. & Deisenhofer, J., May 27 1999, In : Nature Structural Biology. 6, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

458 Scopus citations

Crystal structure of the receptor-binding domain of adenovirus type 5 fiberprotein at 1.7 Å resolution

Xia, D., Henry, L. J., Gerard, R. D. & Deisenhofer, J., Dec 1994, In : Structure. 2, 12, p. 1259-1270 12 p.

Research output: Contribution to journalArticle

229 Scopus citations

Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA

Suno, R., Kimura, K. T., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Horita, S., Tsujimoto, H., Tawaramoto, M. S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M. & 4 others, Rosenbaum, D. M., Iwata, S., Shimamura, T. & Kobayashi, T., Jan 2 2018, In : Structure. 26, 1, p. 7-19.e5

Research output: Contribution to journalArticle

22 Scopus citations

Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences

Taylor, A. B., Smith, B. S., Kitada, S., Kojima, K., Miyaura, H., Otwinowski, Z., Ito, A. & Deisenhofer, J., Aug 11 2001, In : Structure. 9, 7, p. 615-625 11 p.

Research output: Contribution to journalArticle

164 Scopus citations

C-terminal binding domain of Rho GDP-dissociation inhibitor directs N- terminal inhibitory peptide to GTPases

Gosser, Y. Q., Nomanbhoy, T. K., Aghazadeh, B., Manor, D., Combs, C., Cerione, R. A. & Rosen, M. K., Jun 19 1997, In : Nature. 387, 6635, p. 814-819 6 p.

Research output: Contribution to journalArticle

139 Scopus citations

C-terminal ECFP fusion impairs synaptotagmin 1 function: Crowding out synaptotagmin 1

Han, W., Rhee, J. S., Maximov, A., Lin, W., Hammer, R. E., Rosenmund, C. & Südhof, T. C., Feb 11 2005, In : Journal of Biological Chemistry. 280, 6, p. 5089-5100 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Cytochrome c1 of baker's yeast. I. Isolation and properties

Ross, E. & Schatz, G., Jan 1 1976, In : Journal of Biological Chemistry. 251, 7, p. 1991-1996 6 p.

Research output: Contribution to journalArticle

46 Scopus citations
37 Scopus citations

Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice

Yokode, M., Pathak, R. K., Hammer, R. E., Brown, M. S., Goldstein, J. L. & Anderson, R. G. W., May 11 1992, In : Journal of Cell Biology. 117, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Cytoskeletal waves in the absence of molecular motors

Doubrovinski, K. & Kruse, K., Jul 1 2008, In : EPL. 83, 1, 18003.

Research output: Contribution to journalArticle

39 Scopus citations

Cytosolic calcium transients: Spatial localization and role in drosophila photoreceptor cell function

Ranganathan, R., Bacskai, B. J., Tsien, R. Y. & Zuker, C. S., Oct 1994, In : Neuron. 13, 4, p. 837-848 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi

Marivin, A., Maziarz, M., Zhao, J., DiGiacomo, V., Calvo, I. O., Mann, E. A., Ear, J., Blanco-Canosa, J. B., Ross, E. M., Ghosh, P. & Garcia-Marcos, M., Feb 21 2020, In : Journal of Biological Chemistry. 295, 8, p. 2270-2284 15 p.

Research output: Contribution to journalArticle

Data publication with the structural biology data grid supports live analysis

Meyer, P. A., Socias, S., Key, J., Ransey, E., Tjon, E. C., Buschiazzo, A., Lei, M., Botka, C., Withrow, J., Neau, D., Rajashankar, K., Anderson, K. S., Baxter, R. H., Blacklow, S. C., Boggon, T. J., Bonvin, A. M. J. J., Borek, D., Brett, T. J., Caflisch, A., Chang, C. I. & 50 others, Chazin, W. J., Corbett, K. D., Cosgrove, M. S., Crosson, S., Dhe-Paganon, S., Di Cera, E., Drennan, C. L., Eck, M. J., Eichman, B. F., Fan, Q. R., Ferré-D'Amaré, A. R., Fromme, J. C., Garcia, K. C., Gaudet, R., Gong, P., Harrison, S. C., Heldwein, E. E., Jia, Z., Keenan, R. J., Kruse, A. C., Kvansakul, M., McLellan, J. S., Modis, Y., Nam, Y., Otwinowski, Z., Pai, E. F., Pereira, P. J. B., Petosa, C., Raman, C. S., Rapoport, T. A., Roll-Mecak, A., Rosen, M. K., Rudenko, G., Schlessinger, J., Schwartz, T. U., Shamoo, Y., Sondermann, H., Tao, Y. J., Tolia, N. H., Tsodikov, O. V., Westover, K. D., Wu, H., Foster, I., Fraser, J. S., Maia, F. R. N. C., Gonen, T., Kirchhausen, T., Diederichs, K., Crosas, M. & Sliz, P., Mar 7 2016, In : Nature communications. 7, 10882.

Research output: Contribution to journalArticle

64 Scopus citations

Deconstruction of the ras switching cycle through saturation mutagenesis

Bandaru, P., Shah, N. H., Bhattacharyya, M., Barton, J. P., Kondo, Y., Cofsky, J. C., Gee, C. L., Chakraborty, A. K., Kortemme, T., Ranganathan, R. & Kuriyan, J., Jul 7 2017, In : eLife. 6, e27810.

Research output: Contribution to journalArticle

23 Scopus citations

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

Shimomura, I., Matsuda, M., Hammer, R. E., Bashmakov, Y., Brown, M. S. & Goldstein, J. L., Jan 1 2000, In : Molecular cell. 6, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

Open Access
651 Scopus citations
176 Scopus citations

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

Rashid, S., Curtis, D. E., Garuti, R., Anderson, N. H., Bashmakov, Y., Ho, Y. K., Hammer, R. E., Moon, Y. A. & Horton, J. D., Apr 12 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 15, p. 5374-5379 6 p.

Research output: Contribution to journalArticle

483 Scopus citations

Defective dendritic cell (DC) function in a HLA-B27 transgenic rat model of spondyloarthropathy (SpA)

Stagg, A. J., Breban, M., Hammer, R. E., Knight, S. C. & Taurog, J. D., Jan 1 1995, In : Advances in experimental medicine and biology. 378, p. 557-559 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Defective forebrain development in mice lacking gp330/megalin

Willnow, T. E., Hilpert, J., Armstrong, S. A., Rohlmann, A., Hammer, R. E., Burns, D. K. & Herz, J., Aug 6 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 16, p. 8460-8464 5 p.

Research output: Contribution to journalArticle

383 Scopus citations