Research Output

β-Adrenergic receptors display intramolecular disulfide bridges in situ: Analysis by immunoblotting and functional reconstitution

Moxham, C. P., Ross, E. M., George, S. T. & Malbon, C. C., Jan 1 1988, In : Molecular Pharmacology. 33, 5, p. 486-492 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

α-neurexins couple Ca 2+ channels to synaptic vesicle exocytosis

Missier, M., Zhang, W., Rohlmann, A., Kattenstroth, G., Hammer, R. E., Gottmann, K. & Südhof, T. C., Jun 26 2003, In : Nature. 423, 6943, p. 939-948 10 p.

Research output: Contribution to journalArticle

446 Scopus citations

α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells

Lesner, N. P., Gokhale, A. S., Kota, K., DeBerardinis, R. J. & Mishra, P., Jul 2020, In : Metabolic Engineering. 60, p. 157-167 11 p.

Research output: Contribution to journalArticle

Open Access
1475 Scopus citations

X-ray crystallographic studies on an inhibitor-induced conformational change of the iron-sulfur protein in mitochondrial BC1 complex

Kim, H., Xia, D., Deisenhofer, J., Yu, C. A., Kachurin, A., Zhang, L. & Yu, L., Dec 1 1997, In : FASEB Journal. 11, 9, p. A1083

Research output: Contribution to journalArticle

6 Scopus citations

WNK1 promotes PIP2 synthesis to coordinate growth factor and GPCR-Gq signaling

An, S. W., Cha, S. K., Yoon, J., Chang, S., Ross, E. M. & Huang, C. L., Dec 6 2011, In : Current Biology. 21, 23, p. 1979-1987 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Wiring visual systems: common and divergent mechanisms and principles

Kolodkin, A. L. & Hiesinger, P. R., Feb 1 2017, In : Current Opinion in Neurobiology. 42, p. 128-135 8 p.

Research output: Contribution to journalReview article

11 Scopus citations

Why kinesin is so processive

Toprak, E., Yildiz, A., Hoffman, M. T., Rosenfeld, S. S. & Selvin, P. R., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 12717-12722 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Who's In and Who's Out—Compositional Control of Biomolecular Condensates

Ditlev, J. A., Case, L. B. & Rosen, M. K., Jan 1 2018, (Accepted/In press) In : Journal of Molecular Biology.

Research output: Contribution to journalArticle

47 Scopus citations

White fat progenitor cells reside in the adipose vasculature

Tang, W., Zeve, D., Suh, J. M., Bosnakovski, D., Kyba, M., Hammer, R. E., Tallquist, M. D. & Graff, J. M., Oct 24 2008, In : Science. 322, 5901, p. 583-586 4 p.

Research output: Contribution to journalArticle

725 Scopus citations

WASP recruitment to the T cell:APC contact site occurs independently of Cdc42 activation

Cannon, J. L., Labno, C. M., Bosco, G., Seth, A., McGavin, M. H. K., Siminovitch, K. A., Rosen, M. K. & Burkhardt, J. K., Jan 1 2001, In : Immunity. 15, 2, p. 249-259 11 p.

Research output: Contribution to journalArticle

130 Scopus citations

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

Jia, D., Gomez, T. S., Metlagel, Z., Umetani, J., Otwinowski, Z., Rosen, M. K. & Billadeau, D. D., Jun 8 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 23, p. 10442-10447 6 p.

Research output: Contribution to journalArticle

130 Scopus citations

Viral hijack of receptors

Ross, E. M., Jan 1 1990, In : Nature. 344, 6268, p. 707-708 2 p.

Research output: Contribution to journalShort survey

5 Scopus citations

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: Interplay with cerebral blood flow

Li, H., Guo, Q., Inoue, T., Polito, V. A., Tabuchi, K., Hammer, R. E., Pautler, R. G., Taffet, G. E. & Zheng, H., Aug 9 2014, In : Molecular Neurodegeneration. 9, 1, 28.

Research output: Contribution to journalArticle

44 Scopus citations

Valosin-containing protein (VCP/p97) inhibitors relieve mitofusin-dependent mitochondrial defects due to VCP disease mutants

Zhang, T., Mishra, P., Hay, B. A., Chan, D. & Guo, M., Mar 21 2017, In : eLife. 6, e17834.

Research output: Contribution to journalArticle

23 Scopus citations
599 Scopus citations

Use of gene transfer to increase animal growth

Hammer, R. E., Brinster, R. L. & Palmiter, R. D., 1985, In : Cold Spring Harbor symposia on quantitative biology. VOL. 50, p. 379-387 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway

Jiang, L. I., Collins, J., Davis, R., Lin, K. M., DeCamp, D., Roach, T., Hsueh, R., Rebres, R. A., Ross, E. M., Taussig, R., Fraser, I. & Sternweis, P. C., Apr 6 2007, In : Journal of Biological Chemistry. 282, 14, p. 10576-10584 9 p.

Research output: Contribution to journalArticle

175 Scopus citations

Unidirectionality of charge separation in reaction centers of photosynthetic bacteria

Michel-Beyerle, M. E., Plato, M., Deisenhofer, J., Michel, H., Bixon, M. & Jortner, J., 1988, In : BBA - Bioenergetics. 932, C, p. 52-70 19 p.

Research output: Contribution to journalArticle

182 Scopus citations

Unfolding and melting of DNA (RNA) hairpins: The concept of structure-specific 2D dynamic landscapes

Lin, M. M., Meinhold, L., Shorokhov, D. & Zewail, A. H., 2008, In : Physical Chemistry Chemical Physics. 10, 29, p. 4227-4239 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Uncoupling Kapβ2 substrate dissociation and ran binding

Chook, Y. M., Jung, A., Rosen, M. K. & Blobel, G., Jun 4 2002, In : Biochemistry. 41, 22, p. 6955-6966 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Uncoupling conformational change from GTP hydrolysis in a heterotrimetric G protein α-subunit

Thomas, C. J., Du, X., Li, P., Wang, Y., Ross, E. M. & Sprang, S. R., May 18 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7560-7565 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P 3 response in Dictyostelium cells

Ma, L., Janetopoulos, C., Yang, L., Devreotes, P. N. & Iglesias, P. A., Dec 2004, In : Biophysical journal. 87, 6, p. 3764-3774 11 p.

Research output: Contribution to journalArticle

115 Scopus citations

Two 3' sequences direct adult erythroid-specific expression of human β-globulin genes in transgenic mice

Behringer, R. R., Hammer, R. E., Brinster, R. L., Palmiter, R. D. & Townes, T. M., Jan 1 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 20, p. 7056-7060 5 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

Twists and turns on G-protein signalling pathways

Ross, E. M., Oct 1992, In : Current Biology. 2, 10, p. 517-519 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
48 Scopus citations

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism

Updegraff, B. L., Zhou, X., Guo, Y., Padanad, M. S., Chen, P. H., Yang, C., Sudderth, J., Rodriguez-Tirado, C., Girard, L., Minna, J. D., Mishra, P., DeBerardinis, R. J. & O'Donnell-Mendell, K. A., Jan 1 2018, (Accepted/In press) In : Cell Reports.

Research output: Contribution to journalArticle

5 Scopus citations

Transgenic Progeny Inherit Tissue-Specific Expression of Rat Elastase I Genes

MacDonald, R. J., Hammer, R. E., Swift, G. H., Davis, B. P. & Brinster, R. L., Oct 1986, In : DNA. 5, 5, p. 393-401 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Transgenic mice expressing human ApoB95 and ApoB97. Evidence that sequences within the carboxyl-terminal portion of human apoB100 are important for the assembly of lipoprotein(a)

McCormick, S. P. A., Ng, J. K., Cham, C. M., Taylor, S., Marcovina, S. M., Segrest, J. P., Hammer, R. E. & Young, S. G., Sep 19 1997, In : Journal of Biological Chemistry. 272, 38, p. 23616-23622 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein (a)

Linton, M. F., Farese, R. V., Chiesa, G., Grass, D. S., Chin, P., Hammer, R. E., Hobbs, H. H. & Young, S. G., Dec 1993, In : Journal of Clinical Investigation. 92, 6, p. 3029-3037 9 p.

Research output: Contribution to journalArticle

Open Access
203 Scopus citations

Transgenic mice expressing a human apolipoprotein[a] allele

Acquati, F., Hammer, R. E., Ercoli, B., Mooser, V., Ruixan, T., Rönicke, V., Michalich, A., Chiesa, G., Taramelli, R., Hobbs, H. H. & Müller, H. J., Jun 1 1999, In : Journal of lipid research. 40, 6, p. 994-1006 13 p.

Research output: Contribution to journalArticle

15 Scopus citations
Open Access
145 Scopus citations

Transfer of the inflammatory disease of HLA-B27 transgenic rats by bone marrow engraftment

Breban, M., Hammer, R. E., Richardson, J. A. & Taurog, J. D., Nov 1 1993, In : Journal of Experimental Medicine. 178, 5, p. 1607-1616 10 p.

Research output: Contribution to journalArticle

Open Access
124 Scopus citations

Tradeoffs and optimality in the evolution of gene regulation

Poelwijk, F. J., De Vos, M. G. J. & Tans, S. J., Aug 5 2011, In : Cell. 146, 3, p. 462-470 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

TOXCAT: A measure of transmembrane helix association in a biological membrane

Russ, W. P. & Engelman, D. M., Feb 2 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 3, p. 863-868 6 p.

Research output: Contribution to journalArticle

307 Scopus citations

Towards automatic image analysis and assessment of the multicellular apoptosis process

Ziraldo, R., Link, N., Abrams, J. & Ma, L., May 1 2015, In : IET Image Processing. 9, 5, p. 424-433 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

TonB-dependent receptors - Structural perspectives

Ferguson, A. D. & Deisenhofer, J., Oct 11 2002, In : Biochimica et Biophysica Acta - Biomembranes. 1565, 2, p. 318-332 15 p.

Research output: Contribution to journalReview article

98 Scopus citations

Tolerance to Liver‐Specific Antigens

Forman D.M.D/Ph.D., J. M., Wieties, K. & Hammer, R. E., Aug 1991, In : Immunological Reviews. 122, 1, p. 33-46 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Liu, Y., Nguyen, P. T., Wang, X., Zhao, Y., Meacham, C. E., Zou, Z., Bordieanu, B., Johanns, M., Vertommen, D., Wijshake, T., May, H., Xiao, G., Shoji-Kawata, S., Rider, M. H., Morrison, S. J., Mishra, P. & Levine, B., Feb 27 2020, In : Nature. 578, 7796, p. 605-609 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice

Pathak, R. K., Yokode, M., Hammer, R. E., Hofmann, S. L., Brown, M. S., Goldstein, J. L. & Anderson, R. G. W., Aug 1990, In : Journal of Cell Biology. 111, 2, p. 347-359 13 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice

Low, M. J., Hammer, R. E., Goodman, R. H., Habener, J. F., Palmiter, R. D. & Brinster, R. L., May 1985, In : Cell. 41, 1, p. 211-219 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice

Swift, G. H., Hammer, R. E., MacDonald, R. J. & Brinster, R. L., Oct 1984, In : Cell. 38, 3, p. 639-646 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Tissue‐specific Expression of Pancreatic Genes in Transgenic Mice

MacDonald, R. J., Hammer, R. E., Swift, G. H., Ornitz, D. M., Davis, B. P., Palmiter, R. D. & Brinster, R. L., Oct 1986, In : Annals of the New York Academy of Sciences. 478, 1, p. 131-146 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

Tissue-Specific Expression of Kallikrein Family Transgenes in Mice and Rats

Smith, M. S., Lechago, J., Wines, D. R., MacDonald, R. J. & Hammer, R. E., Jun 1992, In : DNA and Cell Biology. 11, 5, p. 345-358 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Tissue-Specific, Developmental, Hormonal, and Dietary Regulation of Rat Phosphoenolpyruvate Carboxykinase-Human Growth Hormone Fusion Genes in Transgenic Mice

Short, M. K., Clouthier, D. E., Schaefer, I. M., Hammer, R. E., Magnuson, M. A. & Beale, E. G., Mar 1992, In : Molecular and cellular biology. 12, 3, p. 1007-1020 14 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations

Timing Correlations in Proteins Predict Functional Modules and Dynamic Allostery

Lin, M. M., May 4 2016, In : Journal of the American Chemical Society. 138, 15, p. 5036-5043 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tie2-Cre transgenic mice: A new model for endothelial cell-lineage analysis in vivo

Kisanuki, Y. Y., Hammer, R. E., Miyazaki, J. I., Williams, S. C., Richardson, J. A. & Yanagisawa, M., Feb 15 2001, In : Developmental Biology. 230, 2, p. 230-242 13 p.

Research output: Contribution to journalArticle

797 Scopus citations

Threshold dissociation and molecular modeling of transition metal complexes of flavonoids

Zhang, J., Brodbelt, J. S. & Wang, J., Feb 1 2005, In : Journal of the American Society for Mass Spectrometry. 16, 2, p. 139-151 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Three-dimensional structure of photosynthetic reaction center from purple bacteria

Miki, K., Deisenhofer, J. & Michel, H., May 1 1989, In : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 34, 6, p. 726-740 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Three-dimensional structure and functions of bovine heart mitochondrial cytochrome bc1 complex

Yu, C. A., Xia, D., Kim, H., Deisenhofer, J., Kachurin, A. M., Zhang, L., Deng, K. P. & Yu, L., Dec 1 1998, In : BioFactors. 8, 3-4, p. 187-189 3 p.

Research output: Contribution to journalShort survey

1 Scopus citations