Research Output

Article

1H and 15N assignments and secondary structure of the Src SH3 domain

Yu, H., Rosen, M. K. & Schreiber, S. L., Jun 7 1993, In : FEBS Letters. 324, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

3D-QSAR studies of arylpyrazole antagonists of cannabinoid receptor subtypes CB1 and CB2. A combined NMR and CoMFA approach

Chen, J. Z., Han, X. W., Liu, Q., Makriyannis, A., Wang, J. & Xie, X. Q., Jan 26 2006, In : Journal of Medicinal Chemistry. 49, 2, p. 625-636 12 p.

Research output: Contribution to journalArticle

54 Scopus citations

4D electron microscopy of T cell activation

Lu, Y., Yoo, B. K., Ng, A. H. C., Kim, J., Yeom, S., Tang, J., Lin, M. M., Zewail, A. H. & Heath, J. R., Oct 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22014-22019 6 p.

Research output: Contribution to journalArticle

Open Access

5-Hydroxytryptamine induced disruption of implantation in the rat: Possible modes of action

Hammer, R. E. & Mitchell, J. A., Jan 1 1980, In : Biology of reproduction. 22, SUPPL. 1, p. No. 18

Research output: Contribution to journalArticle

1 Scopus citations

Ab initio studies of cellulose I: Crystal structure, intermolecular forces, and interactions with water

Li, Y., Lin, M. & Davenport, J. W., Jun 16 2011, In : Journal of Physical Chemistry C. 115, 23, p. 11533-11539 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice

Johnson, E. B., Hammer, R. E. & Herz, J., Nov 15 2005, In : Human molecular genetics. 14, 22, p. 3523-3538 16 p.

Research output: Contribution to journalArticle

97 Scopus citations

Accelerated conformational entropy calculations using graphic processing units

Zhang, Q., Wang, J., Guerrero, G. D., Cecilia, J. M., García, J. M., Li, Y., Pérez-Sánchez, H. & Hou, T., Aug 26 2013, In : Journal of Chemical Information and Modeling. 53, 8, p. 2057-2064 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Accurate quantification of expression of transgenes marked with restriction endonuclease site polymorphisms by RT-PCR

Li, S., George-Raizen, J. B., Hammer, R. E. & Garrard, W. T., Oct 21 1998, In : BioTechniques. 25, 4, p. 558-562 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Acetate dependence of tumors

Comerford, S. A., Huang, Z., Du, X., Wang, Y., Cai, L., Witkiewicz, A., Walters, H., Tantawy, M. N., Fu, A., Manning, H. C., Horton, J. D., Hammer, R. E., McKnight, S. L. & Tu, B. P., Dec 18 2014, In : Cell. 159, 7, p. 1591-1602 12 p.

Research output: Contribution to journalArticle

252 Scopus citations

A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation

Goldman, M. A., Stokes, K. R., Idzerda, R. L., McKnight, G. S., Hammer, R. E., Brinster, R. L. & Gartler, S. M., Jan 1 1987, In : Science. 236, 4801, p. 593-595 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Db1 homology domain

Amarasinghe, G. K. & Rosen, M. K., Nov 22 2005, In : Biochemistry. 44, 46, p. 15257-15268 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

A Comparison of Three Heuristic Algorithms for Molecular Docking

Hou, T. J., Wang, J. M. & Xu, X. J., Jul 1 1999, In : Chinese Chemical Letters. 10, 7, p. 615-618 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

A composition-dependent molecular clutch between T cell signaling condensates and actin

Ditlev, J. A., Vega, A. R., Köster, D. V., Su, X., Tani, T., Lakoduk, A. M., Vale, R. D., Mayor, S., Jaqaman, K. & Rosen, M. K., Jul 2019, In : eLife. 8, e42695.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

A connected set algorithm for the identification of spatially contiguous regions in crystallographic envelopes

Hunt, J. F., Vellieux, F. M. D. & Deisenhofer, J., Jan 1 1997, In : Acta Crystallographica Section D: Biological Crystallography. 53, 4, p. 434-437 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

A conserved amphipathic helix in WASP/scar proteins is essential for activation of Arp2/3 complex

Panchal, S. C., Kaiser, D. A., Torres, E., Pollard, T. D. & Rosen, M. K., Aug 1 2003, In : Nature Structural Biology. 10, 8, p. 591-598 8 p.

Research output: Contribution to journalArticle

118 Scopus citations

A Continuum Poisson-Boltzmann Model for Membrane Channel Proteins

Xiao, L., Diao, J., Greene, DA., Wang, J. & Luo, R., Jul 11 2017, In : Journal of Chemical Theory and Computation. 13, 7, p. 3398-3412 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

Srinivasan, N., Gordon, O., Ahrens, S., Franz, A., Deddouche, S., Chakravarty, P., Phillips, D., Yunus, A. A., Rosen, M. K., Valente, R. S., Teixeira, L., Thompson, B., Dionne, M. S., Wood, W. & Reis e Sousa, C., Nov 22 2016, In : eLife. 5, NOVEMBER2016, e19662.

Research output: Contribution to journalArticle

23 Scopus citations

Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes

Westerberg, L. S., Meelu, P., Baptista, M., Eston, M. A., Adamovich, D. A., Cotta-de-Almeida, V., Seed, B., Rosen, M. K., Vandenberghe, P., Thrasher, A. J., Klein, C., Alt, F. W. & Snapper, S. B., Jun 7 2010, In : Journal of Experimental Medicine. 207, 6, p. 1145-1152 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq

Chang, S. & Ross, E. M., Sep 20 2012, In : PloS one. 7, 9, e45651.

Research output: Contribution to journalArticle

11 Scopus citations

Activation of a matrix processing peptidase from the crystalline cytochrome complex of bovine heart mitochondria

Deng, K., Zhang, L., Kachurin, A. M., Yu, L., Xia, D., Kim, H., Deisenhofer, J. & Yu, C. A., Aug 14 1998, In : Journal of Biological Chemistry. 273, 33, p. 20752-20757 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
526 Scopus citations

Activation of the inhibitory GTP-binding protein of adenylate cyclase, G(i), by β-adrenergic receptors in reconstituted phospholipid vesicles

Asano, T., Katada, T., Gilman, A. G. & Ross, E. M., Jan 1 1984, In : Journal of Biological Chemistry. 259, 15, p. 9351-9354 4 p.

Research output: Contribution to journalArticle

91 Scopus citations

Additional human β2-microglobulin curbs HLA-B27 misfolding and promotes arthritis and spondylitis without colitis in male HLA-B27-transgenic rats

Tran, T. M., Dorris, M. L., Satumtira, N., Richardson, J. A., Hammer, R. E., Shang, J. & Taurog, J. D., Apr 1 2006, In : Arthritis and rheumatism. 54, 4, p. 1317-1327 11 p.

Research output: Contribution to journalArticle

118 Scopus citations

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells

Haga, T., Ross, E. M., Anderson, H. J. & Gilman, A. G., Jan 1 1977, In : Proceedings of the National Academy of Sciences of the United States of America. 74, 5, p. 2016-2020 5 p.

Research output: Contribution to journalArticle

92 Scopus citations

Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator-activated receptor γ and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo

Devine, J. H., Eubank, D. W., Clouthier, D. E., Tontonoz, P., Spiegelman, B. M., Hammer, R. E. & Beale, E. G., May 7 1999, In : Journal of Biological Chemistry. 274, 19, p. 13604-13612 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

ADME evaluation in drug discovery. 7. prediction of oral absorption by correlation and classification

Hou, T., Wang, J., Zhang, W. & Xu, X., Jan 1 2007, In : Journal of Chemical Information and Modeling. 47, 1, p. 208-218 11 p.

Research output: Contribution to journalArticle

138 Scopus citations

ADME evaluation in drug discovery. 8. The prediction of human intestinal absorption by a support vector machine

Hou, T., Wang, J. & Li, Y., Nov 1 2007, In : Journal of Chemical Information and Modeling. 47, 6, p. 2408-2415 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

ADME evaluation in drug discovery. 9. Prediction of oral bioavailability in humans based on molecular properties and structural fingerprints

Tian, S., Li, Y., Wang, J., Zhang, J. & Hou, T., Jun 6 2011, In : Molecular Pharmaceutics. 8, 3, p. 841-851 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

ADMET evaluation in drug discovery. 11. PharmacoKinetics Knowledge Base (PKKB): A comprehensive database of pharmacokinetic and toxic properties for drugs

Cao, D., Wang, J., Zhou, R., Li, Y., Yu, H. & Hou, T., May 25 2012, In : Journal of Chemical Information and Modeling. 52, 5, p. 1132-1137 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

ADMET evaluation in drug discovery. 12. Development of binary classification models for prediction of hERG potassium channel blockage

Wang, S., Li, Y., Wang, J., Chen, L., Zhang, L., Yu, H. & Hou, T., Apr 2 2012, In : Molecular Pharmaceutics. 9, 4, p. 996-1010 15 p.

Research output: Contribution to journalArticle

93 Scopus citations

A DREAM challenge to build prediction models for short-term discontinuation of docetaxel in metastatic castration- resistant prostate cancer

Prostate Cancer DREAM Challenge Community, Jan 1 2017, In : JCO Clinical Cancer Informatics. 2017, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

A Drosophila mutant defective in extracellular calcium-dependent photoreceptor deactivation and rapid desensitization

Ranganathan, R., Harris, G. L., Stevens, C. F. & Zuker, C. S., Jan 1 1991, In : Nature. 354, 6350, p. 230-232 3 p.

Research output: Contribution to journalArticle

158 Scopus citations

A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activity

Chang, C. I., Pili-Floury, S., Hervé, M., Parquet, C., Chelliah, Y., Lemaitre, B., Mengin-Lecreulx, D. & Deisenhofer, J., Sep 1 2004, In : PLoS biology. 2, 9

Research output: Contribution to journalArticle

76 Scopus citations

Adult Apaf-1-deficient mice exhibit male infertility

Honarpour, N., Du, C., Richardson, J. A., Hammer, R. E., Wang, X. & Herz, J., Feb 15 2000, In : Developmental Biology. 218, 2, p. 248-258 11 p.

Research output: Contribution to journalArticle

168 Scopus citations

Advances in computationally modeling human oral bioavailability

Wang, J. & Hou, T., Jun 23 2015, In : Advanced Drug Delivery Reviews. 86, p. 11-16 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

A fully-automated, robust, and versatile algorithm for long-term budding yeast segmentation and tracking

Ezgi Wood, N. & Doncic, A., Mar 1 2019, In : PloS one. 14, 3, e0206395.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A G(s)-selective analog of the receptor-mimetic peptide mastoparan binds to G(s)α in a kinked helical conformation

Sukumar, M., Ross, E. M. & Higashijima, T., Mar 25 1997, In : Biochemistry. 36, 12, p. 3632-3639 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

A global analysis of cross-talk in a mammalian cellular signalling network

Natarajan, M., Lin, K. M., Hsueh, R. C., Sternweis, P. C. & Ranganathan, R., Jun 1 2006, In : Nature Cell Biology. 8, 6, p. 571-580 10 p.

Research output: Contribution to journalArticle

182 Scopus citations

A GTPase-activating protein for the G protein Gα(z). Identification, purification, and mechanism of action

Wang, J., Tu, Y., Woodson, J., Song, X. & Ross, E. M., Feb 28 1997, In : Journal of Biological Chemistry. 272, 9, p. 5732-5740 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae

Baxter, R. H. G., Steinert, S., Chelliah, Y., Volohonsky, G., Levashina, E. A. & Deisenhofer, J., Sep 28 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 39, p. 16817-16822 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene

Beel, K., Cotter, M. M., Blatny, J., Bond, J., Lucas, G., Green, F., Vanduppen, V., Leung, D. W., Rooney, S., Smith, O. P., Rosen, M. K. & Vandenberghe, P., Jan 1 2009, In : British Journal of Haematology. 144, 1, p. 120-126 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Allosteric determinants in guanine nucleotide-binding proteins

Hatley, M. E., Lockless, S. W., Gibson, S. K., Gilman, A. G. & Ranganathan, R., Nov 25 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, SUPPL. 2, p. 14445-14450 6 p.

Research output: Contribution to journalArticle

105 Scopus citations

Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation

Huang, W. Y. C., Ditlev, J. A., Chiang, H. K., Rosen, M. K. & Groves, J. T., Dec 13 2017, In : Journal of the American Chemical Society. 139, 49, p. 18009-18015 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

All You Need Is Mentorship

Weinberg, R. A., Schuldiner, M., Wu, H., Stevens, B., Nielsen, J., Hiesinger, P. R. & Hassan, B. A., Mar 10 2016, In : Cell. 164, 6, p. 1092-1093 2 p.

Research output: Contribution to journalArticle

Alteration in the protein components of catecholamine-sensitive adenylate cyclase during maturation of rat reticulocytes.

Larner, A. C. & Ross, E. M., Sep 25 1981, In : Journal of Biological Chemistry. 256, 18, p. 9551-9557 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

A mathematical model for apoptotic switch in Drosophila

Ziraldo, R. & Ma, L., Oct 1 2015, In : Physical Biology. 12, 5, p. 56003 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

A mesoscopic description of contractile cytoskeletal meshworks

Doubrovinski, K., Polyakov, O. & Kaschube, M., Oct 1 2010, In : European Physical Journal E. 33, 2, p. 105-110 6 p.

Research output: Contribution to journalArticle

Amino acids regulate mTORC1 by an obligate two-step mechanism

Dyachok, J., Earnest, S., Iturraran, E. N., Cobb, M. H. & Ross, E. M., Oct 21 2016, In : Journal of Biological Chemistry. 291, 43, p. 22414-22426 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

A modified soft docking method for proteins and peptides

Wang, J. M., Chen, L. R., Jing, F. & Xu, X. J., Dec 1 1997, In : Chinese Chemical Letters. 8, 7, p. 615-618 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila

Kiselev, A., Socolich, M., Vinós, J., Hardy, R. W., Zuker, C. S. & Ranganathan, R., Jan 1 2000, In : Neuron. 28, 1, p. 139-152 14 p.

Research output: Contribution to journalArticle

Open Access
197 Scopus citations