Research Output

Article

Chimeric muscarinic cholinergic:β-adrenergic receptors that are functionally promiscuous among G proteins

Wong, S. K. F. & Ross, E. M., Jul 22 1994, In : Journal of Biological Chemistry. 269, 29, p. 18968-18976 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα

Peet, D. J., Turley, S. D., Ma, W., Janowski, B. A., Lobaccaro, J. M. A., Hammer, R. E. & Mangelsdorf, D. J., May 29 1998, In : Cell. 93, 5, p. 693-704 12 p.

Research output: Contribution to journalArticle

1134 Scopus citations

Chromophore-protein interactions and the function of the photosynthetic reaction center: A molecular dynamics study

Treutlein, H., Schulten, K., Brünger, A. T., Karplus, M., Deisenhofer, J. & Michel, H., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Cleavage of pig embryos after labeling with fluorescent dyes

Pursel, V. G., Wall, R. J., Hammer, R. E. & Brinster, R. L., Dec 1985, In : Theriogenology. 24, 6, p. 693-700 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cloning and characterization of the Dictyostelium discoideum cycloartenol synthase cDNA

Godzina, S. M., Lovato, M. A., Meyer, M. M., Foster, K. A., Wilson, W. K., Gu, W., De Hostos, E. L. & Matsuda, S. P. T., Jan 1 2000, In : Lipids. 35, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Coevolution-based inference of amino acid interactions underlying protein function

Salinas, V. H. & Ranganathan, R., Jul 19 2018, In : eLife. 7, e34300.

Research output: Contribution to journalArticle

22 Scopus citations

Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)

Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., Jan 1 1997, In : Molecular Pharmacology. 52, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor

Wlodawer, A., Deisenhofer, J. & Huber, R., Jan 5 1987, In : Journal of Molecular Biology. 193, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition

Doncic, A., Atay, O., Valk, E., Grande, A., Bush, A., Vasen, G., Colman-Lerner, A., Loog, M. & Skotheim, J. M., Mar 15 2015, In : Cell. 160, 6, p. 1182-1195 14 p.

Research output: Contribution to journalArticle

20 Scopus citations
7 Scopus citations

Compositional Control of Phase-Separated Cellular Bodies

Banani, S. F., Rice, A. M., Peeples, W. B., Lin, Y., Jain, S., Parker, R. & Rosen, M. K., Jul 28 2016, In : Cell. 166, 3, p. 651-663 13 p.

Research output: Contribution to journalArticle

237 Scopus citations

Computational Redesign of the SHV-1 β-Lactamase/β-Lactamase Inhibitor Protein Interface

Reynolds, K. A., Hanes, M. S., Thomson, J. M., Antczak, A. J., Berger, J. M., Bonomo, R. A., Kirsch, J. F. & Handel, T. M., Oct 24 2008, In : Journal of Molecular Biology. 382, 5, p. 1265-1275 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Computational systems pharmacology analysis of cannabidiol: a combination of chemogenomics-knowledgebase network analysis and integrated in silico modeling and simulation

Bian, Y. M., He, X. B., Jing, Y. K., Wang, L. R., Wang, J. M. & Xie, X. Q., Jan 1 2018, (Accepted/In press) In : Acta Pharmacologica Sinica.

Research output: Contribution to journalArticle

9 Scopus citations
6 Scopus citations

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure

Gotthardt, M., Hammer, R. E., Hübner, N., Monti, J., Witt, C. C., McNabb, M., Richardson, J. A., Granzier, H., Labeit, S. & Herz, J., Feb 21 2003, In : Journal of Biological Chemistry. 278, 8, p. 6059-6065 7 p.

Research output: Contribution to journalArticle

102 Scopus citations

Conformational analysis of peptides using Monte Carlo simulations combined with the genetic algorithm

Wang, J., Hou, T., Chen, L. & Xu, X., Jan 18 1999, In : Chemometrics and Intelligent Laboratory Systems. 45, 1-2, p. 347-351 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Conformational stabilization and crystallization of the SecA translocation ATPase from Bacillus subtilis

Weinkauf, S., Hunt, J. F., Scheuring, J., Henry, L., Fak, J., Oliver, D. B. & Deisenhofer, J., Apr 25 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 4, p. 559-565 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

Gerber, S. H., Rah, J. C., Min, S. W., Liu, X., De Wit, H., Dulubova, I., Meyer, A. C., Rizo-Rey, J., Arancillo, M., Hammer, R. E., Verhage, M., Rosenmund, C. & Südhof, T. C., Sep 12 2008, In : Science. 321, 5895, p. 1507-1510 4 p.

Research output: Contribution to journalArticle

193 Scopus citations

Conformations and coherences in structure determination by ultrafast electron diffraction

Lin, M. M., Shorokhov, D. & Zewail, A. H., Apr 23 2009, In : Journal of Physical Chemistry A. 113, 16, p. 4075-4093 19 p.

Research output: Contribution to journalArticle

14 Scopus citations

Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

Narayanan, C., Gagné, D., Reynolds, K. A. & Doucet, N., Dec 1 2017, In : Scientific reports. 7, 1, 3207.

Research output: Contribution to journalArticle

10 Scopus citations

Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck

Banjade, S., Wu, Q., Mittal, A., Peeples, W. B., Pappu, R. V. & Rosen, M. K., Nov 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. E6426-E6435

Research output: Contribution to journalArticle

56 Scopus citations

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

Devriendt, K., Kim, A. S., Mathijs, G., Frints, S. G. M., Schwartz, M., Van Den Oord, J. J., Verhoef, G. E. G., Boogaerts, M. A., Fryns, J. P., You, D., Rosen, M. K. & Vandenberghe, P., Mar 20 2001, In : Nature genetics. 27, 3, p. 313-317 5 p.

Research output: Contribution to journalArticle

319 Scopus citations

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP

Torres, E. & Rosen, M. K., May 1 2003, In : Molecular cell. 11, 5, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

132 Scopus citations

Continuum polarizable force field within the Poisson-Boltzmann framework

Tan, Y. H., Tan, C., Wang, J. & Luo, R., Jun 26 2008, In : Journal of Physical Chemistry B. 112, 25, p. 7675-7688 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging

Sapir, A., Tsur, A., Koorman, T., Ching, K., Mishra, P., Bardenheier, A., Podolsky, L., Bening-Abu-Shach, U., Boxem, M., Chou, T. F., Broday, L. & Sternberg, P. W., Sep 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 37, p. E3880-E3889

Research output: Contribution to journalArticle

26 Scopus citations

Cooperation between elements of an organ-specific transcriptional enhancer in animals

Kruse, F., Rose, S. D., Swift, G. H., Hammer, R. E. & MacDonald, R. J., Aug 1995, In : Molecular and cellular biology. 15, 8, p. 4385-4394 10 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Cooperativity leads to temporally-correlated fluctuations in the bacteriophage lambda genetic switch

Shenker, J. Q. & Lin, M. M., Apr 8 2015, In : Frontiers in Plant Science. 6, APR, 214.

Research output: Contribution to journalArticle

2 Scopus citations

Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP

Turcotte, M., Tang, W. & Ross, E. M., Aug 2008, In : PLoS Computational Biology. 4, 8, e1000148.

Research output: Contribution to journalArticle

34 Scopus citations

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Onderdonk, A. B., Richardson, J. A., Hammer, R. E. & Taurog, J. D., Dec 1 1998, In : Infection and immunity. 66, 12, p. 6022-6023 2 p.

Research output: Contribution to journalArticle

47 Scopus citations

Correlation of structural and spectroscopic properties of a photosynthetic reaction center

Zinth, W., Knapp, E. W., Fischer, S. F., Kaiser, W., Deisenhofer, J. & Michel, H., Aug 23 1985, In : Chemical Physics Letters. 119, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

53 Scopus citations

Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice

Clouthier, D. E., Hosoda, K., Richardson, J. A., Williams, S. C., Yanagisawa, H., Kuwaki, T., Kumada, M., Hammer, R. E. & Yanagisawai, M., 1998, In : Development. 125, 5, p. 813-824 12 p.

Research output: Contribution to journalArticle

530 Scopus citations

Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs

Tamura, N., Doolittle, L. K., Hammer, R. E., Shelton, J. M., Richardson, J. A. & Garbers, D. L., Dec 7 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 49, p. 17300-17305 6 p.

Research output: Contribution to journalArticle

195 Scopus citations

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex

Xing, C., Zhuang, Y., Xu, T. H., Feng, Z., Zhou, X. E., Chen, M., Wang, L., Meng, X., Xue, Y., Wang, J., Liu, H., McGuire, T. F., Zhao, G., Melcher, K., Zhang, C., Xu, H. E. & Xie, X. Q., Feb 20 2020, In : Cell. 180, 4, p. 645-654.e13

Research output: Contribution to journalArticle

9 Scopus citations

Crystallization and preliminary crystallographic analysis of Escherichia coli DNA photolyase

Park, H. W., Sancar, A. & Deisenhofer, J., Aug 1 1993, In : Journal of Molecular Biology. 231, 4, p. 1122-1125 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Crystallization and preliminary structure of beef heart mitochondrial cytochrome-bc1 complex

Yu, C. A., Xia, J. Z., Kachurin, A. M., Yu, L., Xia, D., Kim, H. & Deisenhofer, J., Jul 18 1996, In : Biochimica et Biophysica Acta - Bioenergetics. 1275, 1-2, p. 47-53 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

Crystallization and preliminary X-ray analysis of ferric enterobactin receptor FepA, an integral membrane protein from Escherichia coli

Smith, B. S., Kobe, B., Kurumbail, R., Buchanan, S. K., Venkatramani, L., Van Der Helm, D. & Deisenhofer, J., Jul 1 1998, In : Acta Crystallographica Section D: Biological Crystallography. 54, 4, p. 697-699 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Crystallization and preliminary X‐ray analysis of fructose 6‐phosphate, 2‐kinase:fructose 2,6‐bisphosphatase

Istvan, E. S., Hasemann, C. A., Kurumbail, R. G., Uyeda, K. & Deisenhofer, J., Nov 1995, In : Protein Science. 4, 11, p. 2439-2441 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
14 Scopus citations
Open Access
58 Scopus citations

Crystallization of mitochondrial cytochrome b-c1 complex from gel with or without reduced pressure

Yu, C. A., Xia, D., Deisenhofer, J. & Yu, L., Nov 4 1994, In : Journal of Molecular Biology. 243, 4, p. 802-805 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
1263 Scopus citations
407 Scopus citations

Crystallographic refinement at 2.3 Å resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis

Deisenhofer, J., Epp, O., Sinning, I. & Michel, H., Feb 24 1995, In : Journal of Molecular Biology. 246, 3, p. 429-457 29 p.

Research output: Contribution to journalArticle

543 Scopus citations

Crystallographic structure studies of an IgG molecule and an Fc fragment

Huber, R., Deisenhofer, J., Colman, P. M., Matsushima, M. & Palm, W., Dec 1 1976, In : Nature. 264, 5585, p. 415-420 6 p.

Research output: Contribution to journalArticle

286 Scopus citations

Crystal structure analysis and molecular model of a complex of citrate synthase with oxaloacetate and S-acetonyl-coenzyme A

Wiegand, G., Remington, S., Deisenhofer, J. & Huber, R., Mar 25 1984, In : Journal of Molecular Biology. 174, 1, p. 205-219 15 p.

Research output: Contribution to journalArticle

91 Scopus citations

Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolution

Hasemann, C. A., Ravichandran, K. G., Peterson, J. A. & Deisenhofer, J., Mar 4 1994, In : Journal of Molecular Biology. 236, 4, p. 1169-1185 17 p.

Research output: Contribution to journalArticle

363 Scopus citations

Crystal structure of a T cell receptor Vα11 (AV11S5) domain: New canonical forms for the first and second complementarity determining regions

Machius, M., Cianga, P., Deisenhofer, J. & Ward, E. S., Jul 20 2001, In : Journal of Molecular Biology. 310, 4, p. 689-698 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity

Huang, Y., Baxter, R., Smith, B. S., Partch, C. L., Colbert, C. L. & Deisenhofer, J., Nov 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 47, p. 17701-17706 6 p.

Research output: Contribution to journalArticle

88 Scopus citations