Research Output

Article

Embryotoxic effects of serotonin during early pregnancy in the rat

Hammer, R. E., Jan 1 1980, In : Anatomical Record. 196, 3, p. 71A-72A

Research output: Contribution to journalArticle

5 Scopus citations

Empirical fitness landscapes reveal accessible evolutionary paths

Poelwijk, F. J., Kiviet, D. J., Weinreich, D. M. & Tans, S. J., Jan 25 2007, In : Nature. 445, 7126, p. 383-386 4 p.

Research output: Contribution to journalArticle

309 Scopus citations

Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton

Chen, X. J., Squarr, A. J., Stephan, R., Chen, B., Higgins, T. E., Barry, D. J., Martin, M. C., Rosen, M. K., Bogdan, S. & Way, M., Sep 8 2014, In : Developmental Cell. 30, 5, p. 569-584 16 p.

Research output: Contribution to journalArticle

45 Scopus citations

Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., Elmquist, J. K., Gerard, R. D., Burgess, S. C., Hammer, R. E., Mangelsdorf, D. J. & Kliewer, S. A., Jun 6 2007, In : Cell Metabolism. 5, 6, p. 415-425 11 p.

Research output: Contribution to journalArticle

935 Scopus citations

Engineering allosteric regulation in protein kinases

Pincus, D., Pandey, J. P., Feder, Z. A., Creixell, P., Resnekov, O. & Reynolds, K. A., Nov 6 2018, In : Science Signaling. 11, 555, eaar3250.

Research output: Contribution to journalArticle

8 Scopus citations

Environmental Dependence of Genetic Constraint

de Vos, M. G. J., Poelwijk, F. J., Battich, N., Ndika, J. D. T. & Tans, S. J., Jun 1 2013, In : PLoS genetics. 9, 6, e1003580.

Research output: Contribution to journalArticle

32 Scopus citations

Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris

Clark, L., Zahm, J. A., Ali, R., Kukula, M., Bian, L., Patrie, S. M., Gardner, K. H., Rosen, M. K. & Rosenbaum, D. M., Feb 19 2016, (Accepted/In press) In : Journal of Biomolecular NMR. p. 1 1 p.

Research output: Contribution to journalArticle

Essential functions of synapsins I and II in synaptic vesicle regulation

Rosahl, T. W., Spillane, D., Missler, M., Herz, J., Selig, D. K., Wolff, J. R., Hammer, R. E., Malenka, R. C. & Südhof, T. C., Jan 1 1995, In : Nature. 375, 6531, p. 488-493 6 p.

Research output: Contribution to journalArticle

581 Scopus citations

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

Guénette, S., Chang, Y., Hiesberger, T., Richardson, J. A., Eckman, C. B., Eckman, E. A., Hammer, R. E. & Herz, J., Jan 25 2006, In : EMBO Journal. 25, 2, p. 420-431 12 p.

Research output: Contribution to journalArticle

113 Scopus citations

Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I

Janz, R., Südhof, T. C., Hammer, R. E., Unni, V., Siegelbaum, S. A. & Bolshakov, V. Y., Nov 1999, In : Neuron. 24, 3, p. 687-700 14 p.

Research output: Contribution to journalArticle

Open Access
227 Scopus citations

Estimation of the available free energy in a LOV2-Jα photoswitch

Yao, X., Rosen, M. K. & Gardner, K. H., Aug 2008, In : Nature chemical biology. 4, 8, p. 491-497 7 p.

Research output: Contribution to journalArticle

86 Scopus citations

Estrogen regulation of the avian transferrin gene in transgenic mice

Hammer, R. E., Idzerda, R. L., Brinster, R. L. & McKnight, G. S., Jan 1 1986, In : Molecular and cellular biology. 6, 4, p. 1010-1014 5 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Evaluating putative mechanisms of the mitotic spindle checkpoint

Doncic, A., Ben-Jacob, E. & Barkai, N., May 3 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 18, p. 6332-6337 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

Süel, G. M., Lockless, S. W., Wall, M. A. & Ranganathan, R., Jan 1 2003, In : Nature Structural Biology. 10, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

589 Scopus citations

Evolutionarily conserved pathways of energetic connectivity in protein families

Lockless, S. W. & Ranganathan, R., Oct 8 1999, In : Science. 286, 5438, p. 295-299 5 p.

Research output: Contribution to journalArticle

927 Scopus citations

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

Toprak, E., Veres, A., Michel, J. B., Chait, R., Hartl, D. L. & Kishony, R., Jan 1 2012, In : Nature genetics. 44, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

370 Scopus citations

Evolutionary potential of a duplicated repressor-operator pair: Simulating pathways using mutation data

Poelwijk, F. J., Kiviet, D. J. & Tans, S. J., May 1 2006, In : PLoS Computational Biology. 2, 5, p. 467-475 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Evolution-Based Functional Decomposition of Proteins

Rivoire, O., Reynolds, K. A. & Ranganathan, R., Jun 2016, In : PLoS Computational Biology. 12, 6, e1004817.

Research output: Contribution to journalArticle

31 Scopus citations

Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase

Stiffler, M. A., Hekstra, D. R. & Ranganathan, R., Feb 26 2015, In : Cell. 160, 5, p. 882-892 11 p.

Research output: Contribution to journalArticle

92 Scopus citations

Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats

Pierce, S. E., Wang, J., Jayawickramarajah, J., Hamilton, A. D. & Brodbelt, J. S., Oct 26 2009, In : Chemistry - A European Journal. 15, 42, p. 11244-11255 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Experience with various techniques for the refinement of protein structures

Deisenhofer, J., Remington, S. J. & Steigemann, W., Jan 1 1985, In : Methods in Enzymology. 115, C, p. 303-323 21 p.

Research output: Contribution to journalArticle

19 Scopus citations

Experimental control of pancreatic development and maintenance

Holland, A. M., Hale, M. A., Kagami, H., Hammer, R. E. & MacDonald, R. J., Sep 17 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 19, p. 12236-12241 6 p.

Research output: Contribution to journalArticle

169 Scopus citations

Experimental spondyloarthropathy in HLA-B27 transgenic rats

Taurog, J. D. & Hammer, R. E., 1996, In : Clinical Rheumatology. 15, SUPPL. 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Expression, Purification, and Characterization of Recombinant Drosophila Choline Acetyltransferase

Wu, D., Schormann, N., Lian, W., Deisenhofer, J. & Hersh, L. B., Oct 1993, In : Journal of Neurochemistry. 61, 4, p. 1416-1422 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Expression of a metallothionein-vasopressin fusion gene in transgenic mice produces hypervasopressinemia and manifestations of nephrogenic diabetes insipidus.

Habener, J. F., Cwikel, B., Hermann, H., Hammer, R. E., Palmiter, R. D. & Brinster, R. L., Dec 1 1988, In : Transactions of the Association of American Physicians. 101, p. 155-162 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

Brinster, R. L., Ritchie, K. A., Hammer, R. E., O'Brien, R. L., Arp, B. & Storb, U., Dec 1 1983, In : Nature. 306, 5941, p. 332-336 5 p.

Research output: Contribution to journalArticle

102 Scopus citations

Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy-Cataplexy in the Rat

Beuckmann, C. T., Sinton, C. M., Williams, S. C., Richardson, J. A., Hammer, R. E., Sakurai, T. & Yanagisawa, M., May 5 2004, In : Journal of Neuroscience. 24, 18, p. 4469-4477 9 p.

Research output: Contribution to journalArticle

140 Scopus citations

Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA

Chiesa, G., Johnson, D. F., Yao, Z., Innerarity, T. L., Mahley, R. W., Young, S. G., Hammer, R. E. & Hobbs, H. H., Jan 1 1993, In : Journal of Biological Chemistry. 268, 32, p. 23747-23750 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth

Hammer, R. E., Brinster, R. L., Rosenfeld, M. G., Evans, R. M. & Mayo, K. E., Dec 1 1985, In : Nature. 315, 6018, p. 413-416 4 p.

Research output: Contribution to journalArticle

174 Scopus citations

Expression of human muscarinic cholinergic receptors in tobacco

Mu, J. H., Chua, N. H. & Ross, E. M., May 1 1997, In : Plant Molecular Biology. 34, 2, p. 357-362 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I

Miller, K. F., Bolt, D. J., Pursel, V. G., Hammer, R. E., Pinkert, C. A., Palmiter, R. D. & Brinster, R. L., 1989, In : Journal of Endocrinology. 120, 3, p. 481-488 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expression of insulin-like growth factor i in transgenic mice with elevated levels of growth hormone is correlated with growth

Mathews, L. S., Hammer, R. E., Brinster, R. L. & Palmiter, R. D., Jul 1 1988, In : Endocrinology. 123, 1, p. 433-437 5 p.

Research output: Contribution to journalArticle

138 Scopus citations

Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice

Rong, S., Cortés, V. A., Rashid, S., Anderson, N. N., McDonald, J. G., Liang, G., Moon, Y. A., Hammer, R. E. & Horton, J. D., Feb 28 2017, In : eLife. 6, e25015.

Research output: Contribution to journalArticle

39 Scopus citations

Expression of the chicken transferrin gene in transgenic mice

Stanley McKnight, G., Hammer, R. E., Kuenzel, E. A. & Brinster, R. L., Sep 1983, In : Cell. 34, 2, p. 335-341 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Expression of the poly-glutamine-ataxin-3 transgene causes loss of orexin expression: A rat model of narcolepsy

Beuckmann, C. T., Sinton, C. M., Williams, S. C., Richardson, J. A., Hammer, R. E., Sakurai, T. & Yanagisawa, M., May 1 2004, In : Sleep and Biological Rhythms. 2, SUPPL. 1, p. S44

Research output: Contribution to journalArticle

Extracellular domains of α-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels

Zhang, W., Rohlmann, A., Sargsyan, V., Aramuni, G., Hammer, R. E., Südhof, T. C. & Missler, M., Apr 27 2005, In : Journal of Neuroscience. 25, 17, p. 4330-4342 13 p.

Research output: Contribution to journalArticle

107 Scopus citations

Fast approaches for molecular polarizability calculations

Wang, J., Xie, X. Q., Hou, T. & Xu, X., May 24 2007, In : Journal of Physical Chemistry A. 111, 20, p. 4443-4448 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

Sakakibara, I., Fujino, T., Ishii, M., Tanaka, T., Shimosawa, T., Miura, S., Zhang, W., Tokutake, Y., Yamamoto, J., Awano, M., Iwasaki, S., Motoike, T., Okamura, M., Inagaki, T., Kita, K., Ezaki, O., Naito, M., Kuwaki, T., Chohnan, S., Yamamoto, T. T. & 4 others, Hammer, R. E., Kodama, T., Yanagisawa, M. & Sakai, J., Feb 4 2009, In : Cell Metabolism. 9, 2, p. 191-202 12 p.

Research output: Contribution to journalArticle

55 Scopus citations

Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation

Squarr, A. J., Brinkmann, K., Chen, B., Steinbacher, T., Ebnet, K., Rosen, M. K. & Bogdan, S., 2016, In : Journal of Cell Biology. 212, 5, p. 591-603 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Feedforward Regulation Ensures Stability and Rapid Reversibility of a Cellular State

Doncic, A. & Skotheim, J. M., Jun 27 2013, In : Molecular cell. 50, 6, p. 856-868 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs

Cansizoglu, M. F. & Toprak, E., May 11 2017, (Accepted/In press) In : Current Genetics. p. 1-4 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Filament turnover stabilizes contractile cytoskeletal structures

Guthardt Torres, P., Doubrovinski, K. & Kruse, K., Sep 1 2010, In : EPL. 91, 6, 68003.

Research output: Contribution to journalArticle

10 Scopus citations

Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development

Özel, M. N., Langen, M., Hassan, B. A. & Hiesinger, P. R., Oct 29 2015, In : eLife. 4, OCTOBER2015, e10721.

Research output: Contribution to journalArticle

26 Scopus citations

FK506 and Rapamycin Binding to FKBP: Common Elements in Immunophilin-Ligand Complexation

Wandless, T. J., Michnick, S. W., Rosen, M. K., Karplus, M. & Schreiber, S. L., Jan 1 1991, In : Journal of the American Chemical Society. 113, 6, p. 2339-2341 3 p.

Research output: Contribution to journalArticle

32 Scopus citations

Force titration of amino group-terminated self-assembledmonolayers using chemical force microscopy

Zhang, H., He, H. X., Wang, J., Mu, T. & Liu, Z. F., Dec 1 1998, In : Applied Physics A: Materials Science and Processing. 66, SUPPL. 1, p. S269-S271

Research output: Contribution to journalArticle

71 Scopus citations

Force titration of self-assembled monolayer using chemical force microscopy

He, H., Li, C., Wang, J., Zhang, H., Xu, X. & Liu, Z., Dec 1 1997, In : Acta Physico - Chimica Sinica. 13, 4, p. 293-296 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Lin, Y., Protter, D. S. W., Rosen, M. K. & Parker, R., Oct 15 2015, In : Molecular cell. 60, 2, p. 208-219 12 p.

Research output: Contribution to journalArticle

505 Scopus citations

Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity

Alexander, M. S., Shi, X., Voelker, K. A., Grange, R. W., Garcia, J. A., Hammer, R. E. & Garry, D. J., Jan 15 2010, In : Developmental Biology. 337, 2, p. 396-404 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Functional activation of β-adrenergic receptors by thiols in the presence or absence of agonists

Pedersen, S. E. & Ross, E. M., Dec 1 1985, In : Journal of Biological Chemistry. 260, 26, p. 14150-14157 8 p.

Research output: Contribution to journalArticle

63 Scopus citations