Research Output

Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats

Kasof, G. M., Mandelzys, A., Maika, S. D., Hammer, R. E., Curran, T. & Morgan, J. I., 1995, In : Journal of Neuroscience. 15, 6, p. 4238-4249 12 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

Karyopherins and condensates

Springhower, C. E., Rosen, M. K. & Chook, Y. M., Jun 2020, In : Current Opinion in Cell Biology. 64, p. 112-123 12 p.

Research output: Contribution to journalReview article

Open Access

Kernel mechanism of the cyanobacterial circadian clock is a relaxation oscillator

Ma, L. & Ranganathan, R., Dec 1 2011, 2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011. p. 5850-5855 6 p. 6161040. (Proceedings of the IEEE Conference on Decision and Control).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Kinetic control of guanine nucleotide binding to soluble Gα(q)

Markin, V. S. & Ross, E. M., Jul 1 1999, In : Biochemical Pharmacology. 58, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Knowledge-based potential functions in protein design

Russ, W. P. & Ranganathan, R., Aug 1 2002, In : Current Opinion in Structural Biology. 12, 4, p. 447-452 6 p.

Research output: Contribution to journalReview article

61 Scopus citations

Knowledge-based potentials in protein design

Poole, A. M. & Ranganathan, R., Aug 1 2006, In : Current Opinion in Structural Biology. 16, 4, p. 508-513 6 p.

Research output: Contribution to journalReview article

67 Scopus citations

Kristallisation, Kristallstrukturanalyse und Atomares Modell des Komplexes aus Einem Menschlichen Fc-Fragment (Fc) und Fragment B (Fb) Von Protein A aus Staphylococcus Aureus

Translated title of the contribution: Crystallization, Crystal Structure Analysis and Atomic Model of the Complex Formed By A Human Fc Fragment and Fragment B of Protein A from Staphylococcus AureusDeisenhofer, J., Jones, T. A., Huber, R., Sjödahl, J. & Sjöquist, J., Jan 1 1978, In : Hoppe-Seyler's Zeitschrift fur Physiologische Chemie. 359, 2, p. 975-986 12 p.

Research output: Contribution to journalArticle

135 Scopus citations

Kristallographische Studien an einem Fc-Fragment, II. Ein vollständiges Modell nach einer Fourier-Synthese bei 3.5Å Auflösung

Translated title of the contribution: Crystallographic Structural Studies of a Human Fc Fragment II. A Complete Model Based on a Fourier Map at 3.5 Å ResolutionDeisenhofer, J., Colman, P. M., Epp, O. & Huber, R., Aug 1976, In : Hoppe-Seyler's Zeitschrift fur Physiologische Chemie. 357, 2, p. 1421-1434 14 p.

Research output: Contribution to journalArticle

101 Scopus citations

Kristallographische Studien an Einem Menschlichen Fc-Fragment, I. Eine Elektronendichteverteilung bei 4-Å-AuflöSung und ein Teil-Modell

Translated title of the contribution: Crystallographic Structural Studies of A Human Fc-Fragment I. Ara Electron-Density Map at 4 A Resolution and A Partial ModelDeisenhofer, J., Colman, P. M., Huber, R., Haupt, H. & Schwick, G., Jan 1 1976, In : Hoppe-Seyler's Zeitschrift fur Physiologische Chemie. 357, 1, p. 435-446 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Kristallstrukturanalyse und molekülmodell des menschlichen c3a-anaphylatoxins

Huber, R., Scholze, H., Paques, E. P. & Deisenhofer, J., Jan 1 1980, In : Hoppe-Seyler's Zeitschrift fur Physiologische Chemie. 361, 2, p. 1389-1400 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation

Herz, J., Clouthier, D. E. & Hammer, R. E., Oct 30 1992, In : Cell. 71, 3, p. 411-421 11 p.

Research output: Contribution to journalArticle

472 Scopus citations

Learning the pattern of epistasis linking genotype and phenotype in a protein

Poelwijk, F. J., Socolich, M. & Ranganathan, R., Dec 1 2019, In : Nature communications. 10, 1, 4213.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy

Shimomura, I., Hammer, R. E., Ikemoto, S., Brown, M. S. & Goldstein, J. L., Sep 2 1999, In : Nature. 401, 6748, p. 73-76 4 p.

Research output: Contribution to journalArticle

806 Scopus citations

Leveraging symmetry to predict self-assembly of multiple polymers

Lin, M. M., Sep 1 2017, In : Chemical Physics Letters. 683, p. 347-351 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Ligand recognition by SH3 and WW domains: The role of N-alkylation in PPII helices

Aghazadeh, B. & Rosen, M. K., Sep 1999, In : Chemistry and Biology. 6, 9, p. R241-R246

Research output: Contribution to journalReview article

16 Scopus citations

Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models

Nguyen, L. H., Robinton, D. A., Seligson, M. T., Wu, L., Li, L., Rakheja, D., Comerford, S. A., Ramezani, S., Sun, X., Parikh, M. S., Yang, E. H., Powers, J. T., Shinoda, G., Shah, S. P., Hammer, R. E., Daley, G. Q. & Zhu, H., Aug 11 2014, In : Cancer Cell. 26, 2, p. 248-261 14 p.

Research output: Contribution to journalArticle

105 Scopus citations

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis

Lee, Y. K., Schmidt, D. R., Cummins, C. L., Choi, M., Li, P., Zhang, Y., Goodwin, B., Hammer, R. E., Mangelsdorf, D. J. & Kliewer, S. A., Jun 2008, In : Molecular Endocrinology. 22, 6, p. 1345-1356 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

Local complexity of amino acid interactions in a protein core

Jain, R. K. & Ranganathan, R., Jan 1 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 1, p. 111-116 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Local F-actin network links synapse formation and axon branching

Chia, P. H., Chen, B., Li, P., Rosen, M. K. & Shen, K., 2014, In : Cell. 156, 1-2, p. 208-220 13 p.

Research output: Contribution to journalArticle

66 Scopus citations

Loss of Dis3l2 partially phenocopies perlman syndrome in mice and results in upregulation of Igf2 in nephron progenitor cells

Hunter, R. W., Liu, Y., Manjunath, H., Acharya, A., Jones, B. T., Zhang, H., Chen, B., Ramalingam, H., Hammer, R. E., Xie, Y., Richardson, J. A., Rakheja, D., Carroll, T. J. & Mendell, J. T., Jul 1 2018, In : Genes and Development. 32, 13-14, p. 903-908 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Loss-of-Function Analysis of EphA Receptors in Retinotectal Mapping

Feldheim, D. A., Nakamoto, M., Osterfield, M., Gale, N. W., DeChiara, T. M., Rohatgi, R., Yancopoulos, G. D. & Flanagan, J. G., Mar 10 2004, In : Journal of Neuroscience. 24, 10, p. 2542-2550 9 p.

Research output: Contribution to journalArticle

Open Access
116 Scopus citations

Low blood pressure in endothelial cell-specific endothelin 1 knockout mice

Kisanuki, Y. Y., Emoto, N., Ohuchi, T., Widyantoro, B., Yagi, K., Nakayama, K., Kedzierski, R. M., Hammer, R. E., Yanagisawa, H., Williams, S. C., Richardson, J. A., Suzuki, T. & Yanagisawa, M., Jul 2010, In : Hypertension. 56, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

78 Scopus citations
116 Scopus citations

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function

Holmstrom, S. R., Deering, T., Swift, G. H., Poelwijk, F. J., Mangelsdorf, D. J., Kliewer, S. A. & Macdonald, R. J., Aug 15 2011, In : Genes and Development. 25, 16, p. 1674-1679 6 p.

Research output: Contribution to journalArticle

65 Scopus citations

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis

Xian, X., Ding, Y., Dieckmann, M., Zhou, L., Plattner, F., Liu, M., Parks, J. S., Hammer, R. E., Boucher, P., Tsai, S. & Herz, J., Nov 16 2017, In : eLife. 6, e29292.

Research output: Contribution to journalArticle

20 Scopus citations

Lrp4 domains differentially regulate limb/brain development and synaptic plasticity

Pohlkamp, T., Durakoglugil, M. S., Lane-Donovan, C., Xian, X., Johnson, E. B., Hammer, R. E. & Herz, J., Feb 17 2015, In : PloS one. 10, 2, e0116701.

Research output: Contribution to journalArticle

10 Scopus citations

'MAD'ly phasing the extracellular domain of the LDL receptor: A medium-sized protein, large tungsten clusters and multiple non-isomorphous crystals

Rudenko, G., Henry, L., Vonrhein, C., Bricogne, G. & Deisenhofer, J., Nov 1 2003, In : Acta Crystallographica - Section D Biological Crystallography. 59, 11, p. 1978-1986 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Male and female germline specific expression of an EGFP reporter gene in a unique strain of transgenic rats

Cronkhite, J. T., Norlander, C., Furth, J. K., Levan, G., Garbers, D. L. & Hammer, R. E., Aug 1 2005, In : Developmental Biology. 284, 1, p. 171-183 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Mammalian phospholipase C

Kadamur, G. & Ross, E. M., Feb 10 2013, In : Annual review of physiology. 75, p. 127-154 28 p.

Research output: Contribution to journalReview article

197 Scopus citations

Mapping of the mastoparan-binding site on G proteins: Cross-linking of [125I-Tyr3,Cys11]mastoparan to G(o)

Higashijima, T. & Ross, E. M., Sep 23 1991, In : Journal of Biological Chemistry. 266, 19, p. 12655-12661 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins)

Higashijima, T., Uzu, S., Nakajima, T. & Ross, E. M., Jan 1 1988, In : Journal of Biological Chemistry. 263, 14, p. 6491-6494 4 p.

Research output: Contribution to journalArticle

561 Scopus citations

Measurement and analysis of in vitro actin polymerization

Doolittle, L. K., Rosen, M. K. & Padrick, S. B., 2013, Adhesion Protein Protocols. Humana Press Inc., p. 273-293 21 p. (Methods in Molecular Biology; vol. 1046).

Research output: Chapter in Book/Report/Conference proceedingChapter

28 Scopus citations

Measurement of cortical elasticity in Drosophila melanogaster embryos using ferrofluids

Doubrovinski, K., Swan, M., Polyakov, O. & Wieschaus, E. F., Jan 31 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1051-1056 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells

Okumus, B., Landgraf, D., Lai, G. C., Bakhsi, S., Arias-Castro, J. C., Yildiz, S., Huh, D., Fernandez-Lopez, R., Peterson, C. N., Toprak, E., El Karoui, M. & Paulsson, J., May 18 2016, In : Nature communications. 7, 11641.

Research output: Contribution to journalArticle

21 Scopus citations

Mechanism of actin filament nucleation by the bacterial effector VopL

Yu, B., Cheng, H. C., Brautigam, C. A., Tomchick, D. R. & Rosen, M. K., Sep 2011, In : Nature Structural and Molecular Biology. 18, 9, p. 1068-1074 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Mechanism of Rab geranylgeranylation: Formation of the catalytic ternary complex

Anant, J. S., Desnoyers, L., Machius, M., Demeler, B., Hansen, J. C., Westover, K. D., Deisenhofer, J. & Seabra, M. C., Sep 8 1998, In : Biochemistry. 37, 36, p. 12559-12568 10 p.

Research output: Contribution to journalArticle

59 Scopus citations
168 Scopus citations
31 Scopus citations
143 Scopus citations

Mechanistic studies of affinity modulation

Rosen, M. K., Amos, C. D. & Wandless, T. J., Dec 6 2000, In : Journal of the American Chemical Society. 122, 48, p. 11979-11982 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mesolimbic neuropeptide W coordinates stress responses under novel environments

Motoike, T., Long, J. M., Tanaka, H., Sinton, C. M., Skach, A., Williams, S. C., Hammer, R. E., Sakurai, T. & Yanagisawa, M., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 6023-6028 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Mesoscopic reaction-diffusion in intracellular signaling

Elf, J., Dončić, A. & Ehrenberg, M., Sep 19 2003, In : Proceedings of SPIE - The International Society for Optical Engineering. 5110, p. 114-124 11 p.

Research output: Contribution to journalConference article

75 Scopus citations

Metabolic regulation of mitochondrial dynamics

Mishra, P. & Chan, D. C., 2016, In : Journal of Cell Biology. 212, 4, p. 379-387 9 p.

Research output: Contribution to journalArticle

359 Scopus citations

Metal Import through Microbial Membranes

Ferguson, A. D. & Deisenhofer, J., Jan 9 2004, In : Cell. 116, 1, p. 15-24 10 p.

Research output: Contribution to journalReview article

101 Scopus citations

Metallothionein-human GH fusion genes stimulate growth of mice

Palmiter, R. D., Norstedt, G., Gelinas, R. E., Hammer, R. E. & Brinster, R. L., Jan 1 1983, In : Science. 222, 4625, p. 809-814 6 p.

Research output: Contribution to journalArticle

465 Scopus citations

Metallothionein-vasopressin fusion gene expression in transgenic mice. Nephrogenic diabetes insipidus and brain transcripts localized to magnocellular neurons

Habener, J. F., Cwikel, B. J., Hermann, H., Hammer, R. E., Oalmiter, R. D. & Brinster, R. L., Jan 1 1989, In : Journal of Biological Chemistry. 264, 31, p. 18844-18852 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris

Clark, L., Zahm, J. A., Ali, R., Kukula, M., Bian, L., Patrie, S. M., Gardner, K. H., Rosen, M. & Rosenbaum, D. M., May 30 2015, (Accepted/In press) In : Journal of Biomolecular NMR.

Research output: Contribution to journalArticle

30 Scopus citations

MiR-124 regulates diverse aspects of rhythmic behavior in Drosophila

Garaulet, D. L., Sun, K., Li, W., Wen, J., Panzarino, A. M., O’Neil, J. L., Robin Hiesinger, P., Young, M. W. & Lai, E. C., Mar 23 2016, In : Journal of Neuroscience. 36, 12, p. 3414-3421 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer Cells

Moore, R., Ooi, H. K., Kang, T., Bleris, L. & Ma, L., 2015, In : PLoS Computational Biology. 11, 12, e1004653.

Research output: Contribution to journalArticle

23 Scopus citations

MiR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19

Acharya, A., Berry, D. C., Zhang, H., Jiang, Y., Jones, B. T., Hammer, R. E., Graff, J. M. & Mendell, J. T., Oct 1 2019, In : Genes and Development. 33, 19-20, p. 1367-1380 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations