Research Output

1998

Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N)

Korn, B. S., Shimomura, L., Bashmakov, Y., Hammer, R. E., Horton, J. D., Goldstein, J. L. & Brown, M. S., Dec 15 1998, In : Journal of Clinical Investigation. 102, 12, p. 2050-2060 11 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα

Peet, D. J., Turley, S. D., Ma, W., Janowski, B. A., Lobaccaro, J. M. A., Hammer, R. E. & Mangelsdorf, D. J., May 29 1998, In : Cell. 93, 5, p. 693-704 12 p.

Research output: Contribution to journalArticle

1130 Scopus citations

Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease

Onderdonk, A. B., Richardson, J. A., Hammer, R. E. & Taurog, J. D., Dec 1 1998, In : Infection and immunity. 66, 12, p. 6022-6023 2 p.

Research output: Contribution to journalArticle

47 Scopus citations

Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice

Clouthier, D. E., Hosoda, K., Richardson, J. A., Williams, S. C., Yanagisawa, H., Kuwaki, T., Kumada, M., Hammer, R. E. & Yanagisawai, M., 1998, In : Development. 125, 5, p. 813-824 12 p.

Research output: Contribution to journalArticle

530 Scopus citations

Crystallization and preliminary X-ray analysis of ferric enterobactin receptor FepA, an integral membrane protein from Escherichia coli

Smith, B. S., Kobe, B., Kurumbail, R., Buchanan, S. K., Venkatramani, L., Van Der Helm, D. & Deisenhofer, J., Jul 1 1998, In : Acta Crystallographica Section D: Biological Crystallography. 54, 4, p. 697-699 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene

Yanagisawa, H., Yanagisawa, M., Kapur, R. P., Richardson, J. A., Williams, S. C., Clouthier, D. E., De Wit, D., Emoto, N. & Hammer, R. E., Apr 11 1998, In : Development. 125, 5, p. 825-836 12 p.

Research output: Contribution to journalArticle

410 Scopus citations

Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity

Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G. & Worley, P. F., Sep 15 1998, In : Journal of Neuroscience. 18, 18, p. 7178-7188 11 p.

Research output: Contribution to journalArticle

Open Access
249 Scopus citations

Egg culture: The foundation

Hammer, R. E., Dec 2 1998, In : International Journal of Developmental Biology. 42, 7, p. 833-839 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Force titration of amino group-terminated self-assembledmonolayers using chemical force microscopy

Zhang, H., He, H. X., Wang, J., Mu, T. & Liu, Z. F., Dec 1 1998, In : Applied Physics A: Materials Science and Processing. 66, SUPPL. 1, p. S269-S271

Research output: Contribution to journalArticle

71 Scopus citations

Inducible inactivation of hepatic LRP gene by Cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

Rohlmann, A., Gotthardt, M., Hammer, R. E. & Herz, J., Feb 1 1998, In : Journal of Clinical Investigation. 101, 3, p. 689-695 7 p.

Research output: Contribution to journalArticle

Open Access
362 Scopus citations

Inhibitor binding changes domain mobility in the iron-sulfur protein of the mitochondrial bc1 complex from bovine heart

Kim, H., Xia, D., Yu, C. A., Xia, J. Z., Kachurin, A. M., Zhang, L., Yu, L. & Deisenhofer, J., Jul 7 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 14, p. 8026-8033 8 p.

Research output: Contribution to journalArticle

247 Scopus citations
Open Access
633 Scopus citations
115 Scopus citations

Mechanism of Rab geranylgeranylation: Formation of the catalytic ternary complex

Anant, J. S., Desnoyers, L., Machius, M., Demeler, B., Hansen, J. C., Westover, K. D., Deisenhofer, J. & Seabra, M. C., Sep 8 1998, In : Biochemistry. 37, 36, p. 12559-12568 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Neurexin Iα is a major α-latrotoxin receptor that cooperates in α- latrotoxin action

Geppert, M., Khvotchev, M., Krasnoperov, V., Goda, Y., Missler, M., Hammer, R. E., Ichtchenko, K., Petrenko, A. G. & Südhof, T. C., Jan 16 1998, In : Journal of Biological Chemistry. 273, 3, p. 1705-1710 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Neurexophilin binding to α-neurexins. A single LNS domain functions as an independently folding ligand-binding unit

Missler, M., Hammer, R. E. & Südhof, T. C., Dec 25 1998, In : Journal of Biological Chemistry. 273, 52, p. 34716-34723 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily

Wang, J., Ducret, A., Tu, Y., Kozasa, T., Aebersold, R. & Ross, E. M., Oct 2 1998, In : Journal of Biological Chemistry. 273, 40, p. 26014-26025 12 p.

Research output: Contribution to journalArticle

127 Scopus citations

Role of endothelin-1/endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice

Yanagisawa, H., Hammer, R. E., Richardson, J. A., Williams, S. C., Clouthier, D. E. & Yanagisawa, M., Jul 1 1998, In : Journal of Clinical Investigation. 102, 1, p. 22-33 12 p.

Research output: Contribution to journalArticle

Open Access
164 Scopus citations

Structural basis of functions of the mitochondrial cytochrome bc1 complex

Yu, C. A., Xia, D., Kim, H., Deisenhofer, J., Zhang, L., Kachurin, A. M. & Yu, L., Jun 10 1998, In : Biochimica et Biophysica Acta - Bioenergetics. 1365, 1-2, p. 151-158 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Structure and mutagenesis of the Dbl homology domain

Aghazadeh, B., Zhu, K., Kubiseski, T. J., Liu, G. A., Pawson, T., Zheng, Y. & Rosen, M. K., Dec 1 1998, In : Nature Structural Biology. 5, 12, p. 1098-1107 10 p.

Research output: Contribution to journalReview article

108 Scopus citations

Synapsin I is structurally similar to ATP-utilizing enzymes

Esser, L., Wang, C. R., Hosaka, M., Smagula, C. S., C.südhof, T. & Deisenhofer, J., Feb 4 1998, In : EMBO Journal. 17, 4, p. 977-984 8 p.

Research output: Contribution to journalArticle

105 Scopus citations
Open Access
471 Scopus citations

The International Journal of Developmental Biology: Preface

Hammer, R. E. & Behringer, R. R., Jan 1 1998, In : International Journal of Developmental Biology. 42, 7, p. 831-832 2 p.

Research output: Contribution to journalEditorial

The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling

Zeng, W., Xu, X., Popov, S., Mukhopadhyay, S., Chidiac, P., Swistok, J., Danho, W., Yagaloff, K. A., Fisher, S. L., Ross, E. M., Muallem, S. & Wilkie, T. M., Dec 25 1998, In : Journal of Biological Chemistry. 273, 52, p. 34687-34690 4 p.

Research output: Contribution to journalArticle

218 Scopus citations

Theoretical studies on force titration of amino-group-terminated self-assembled monolayers

Wang, J., Zhang, H., He, H., Hou, T., Liu, Z. & Xu, X., Oct 5 1998, In : Journal of Molecular Structure: THEOCHEM. 451, 3, p. 295-303 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLA-B27 transgenic rats

Zhou, B. M., Sayad, A., Simmons, W. A., Jones, R. C., Maika, S. D., Satumtira, N., Dorris, M. L., Gaskell, S. J., Bordoli, R. S., Sartor, R. B., Slaughter, C. A., Richardson, J. A., Hammer, R. E. & Taurog, J. D., Sep 7 1998, In : Journal of Experimental Medicine. 188, 5, p. 877-886 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Three-dimensional structure and functions of bovine heart mitochondrial cytochrome bc1 complex

Yu, C. A., Xia, D., Kim, H., Deisenhofer, J., Kachurin, A. M., Zhang, L., Deng, K. P. & Yu, L., Dec 1 1998, In : BioFactors. 8, 3-4, p. 187-189 3 p.

Research output: Contribution to journalShort survey

1 Scopus citations
Open Access
145 Scopus citations
1997

A connected set algorithm for the identification of spatially contiguous regions in crystallographic envelopes

Hunt, J. F., Vellieux, F. M. D. & Deisenhofer, J., Jan 1 1997, In : Acta Crystallographica Section D: Biological Crystallography. 53, 4, p. 434-437 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

A G(s)-selective analog of the receptor-mimetic peptide mastoparan binds to G(s)α in a kinked helical conformation

Sukumar, M., Ross, E. M. & Higashijima, T., Mar 25 1997, In : Biochemistry. 36, 12, p. 3632-3639 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

A GTPase-activating protein for the G protein Gα(z). Identification, purification, and mechanism of action

Wang, J., Tu, Y., Woodson, J., Song, X. & Ross, E. M., Feb 28 1997, In : Journal of Biological Chemistry. 272, 9, p. 5732-5740 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

A modified soft docking method for proteins and peptides

Wang, J. M., Chen, L. R., Jing, F. & Xu, X. J., Dec 1 1997, In : Chinese Chemical Letters. 8, 7, p. 615-618 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

A new MHC locus that influences class I peptide presentation

Simmons, W. A., Roopenian, D. C., Summerfield, S. G., Jones, R. C., Galocha, B., Christianson, G. J., Maika, S. D., Zhou, M., Gaskell, S. J., Bordoli, R. S., Ploegh, H. L., Slaughter, C. A., Lindahl, K. F., Hammer, R. E. & Taurog, J. D., Nov 1997, In : Immunity. 7, 5, p. 641-651 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Characterization of defective nucleotide excision repair in XPC mutant mice

Cheo, D. L., Ruven, H. J. T., Meira, L. B., Hammer, R. E., Burns, D. K., Tappe, N. J., Van Zeeland, A. A., Mullenders, L. H. F. & Friedberg, E. C., Mar 4 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 374, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)

Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., Jan 1 1997, In : Molecular Pharmacology. 52, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

Xia, D., Yu, C. A., Kim, H., Xia, J. Z., Kachurin, A. M., Zhang, L., Yu, L. & Deisenhofer, J., Jul 4 1997, In : Science. 277, 5322, p. 60-66 7 p.

Research output: Contribution to journalArticle

811 Scopus citations

C-terminal binding domain of Rho GDP-dissociation inhibitor directs N- terminal inhibitory peptide to GTPases

Gosser, Y. Q., Nomanbhoy, T. K., Aghazadeh, B., Manor, D., Combs, C., Cerione, R. A. & Rosen, M. K., Jun 19 1997, In : Nature. 387, 6635, p. 814-819 6 p.

Research output: Contribution to journalArticle

139 Scopus citations
Open Access
326 Scopus citations

Expression of human muscarinic cholinergic receptors in tobacco

Mu, J. H., Chua, N. H. & Ross, E. M., May 1 1997, In : Plant Molecular Biology. 34, 2, p. 357-362 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Force titration of self-assembled monolayer using chemical force microscopy

He, H., Li, C., Wang, J., Zhang, H., Xu, X. & Liu, Z., Dec 1 1997, In : Acta Physico - Chimica Sinica. 13, 4, p. 293-296 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic interaction between hap1/ref-1 and p53

Meira, L. B., Cheo, D. L., Hammer, R. E., Burns, D. K., Reis, A. & Friedberg, E. C., Oct 1997, In : Nature genetics. 17, 2, 1 p.

Research output: Contribution to journalArticle

52 Scopus citations

Global folds of highly deuterated, methyl-protonated proteins by multidimensional NMR

Gardner, K. H., Rosen, M. K. & Kay, L. E., Feb 11 1997, In : Biochemistry. 36, 6, p. 1389-1401 13 p.

Research output: Contribution to journalArticle

233 Scopus citations

Guanosine Triphosphatase-Activating Proteins for Heterotrimeric G-Proteins

Ross, E. M., Wang, J., Tu, Y. & Biddlecome, G. H., 1997, In : Advances in Pharmacology. 42, C, p. 458-461 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-β1 transgenic mice

Clouthier, D. E., Comerford, S. A. & Hammer, R. E., Dec 1 1997, In : Journal of Clinical Investigation. 100, 11, p. 2697-2713 17 p.

Research output: Contribution to journalArticle

Open Access
233 Scopus citations

Identification, expression, and crystallization of the protease- resistant conserved domain of synapsin I

Wang, C. R., Esser, L., Smagula, C. S., Südhof, T. C. & Deisenhofer, J., Oct 1 1997, In : Protein Science. 6, 10, p. 2264-2267 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Inhibition of brain G(z) GAP and other RGS proteins by palmitoylation of G protein α subunits

Tu, Y., Wang, J. & Ross, E. M., Nov 7 1997, In : Science. 278, 5340, p. 1132-1135 4 p.

Research output: Contribution to journalArticle

127 Scopus citations
Open Access
627 Scopus citations

Monoclonal antibody to the HLA class I α3 domain inhibits T cell activation and prolongs cardiac allograft survival in HLA- transgenic mice

Woo, J., Cornejo, M. C., Gao, L., Taurog, J. D., Hammer, R. E. & Buelow, R., Jun 1997, In : Transplant Immunology. 5, 2, p. 112-121 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Novel HY peptide antigens presented by HLA-B271

Simmons, W. A., Summerfield, S. G., Roopenian, D. C., Slaughter, C. A., Zuberi, A. R., Gaskell, S. J., Bordoli, R. S., Hoyes, J., Moomaw, C. R., Colbert, R. A., Leong, L. Y. W., Butcher, G. W., Hammer, R. E. & Taurog, J. D., Dec 1 1997, In : Journal of Immunology. 159, 6, p. 2750-2759 10 p.

Research output: Contribution to journalArticle

26 Scopus citations