Research Output

CDK5RAP2 regulates centriole engagement and cohesion in mice

Barrera, J. A., Kao, L. R., Hammer, R. E., Seemann, J., Fuchs, J. L. & Megraw, T. L., Mar 16 2010, In : Developmental cell. 18, 6, p. 913-926 14 p.

Research output: Contribution to journalArticle

97 Scopus citations

Cell-autonomous and nonautonomous actions of endothelin-A receptor signaling in craniofacial and cardiovascular development

Clouthier, D. E., Williams, S. C., Hammer, R. E., Richardson, J. A. & Yanagisawa, M., Sep 15 2003, In : Developmental Biology. 261, 2, p. 506-519 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cell biology: ATP controls the crowd

Rice, A. M. & Rosen, M. K., May 19 2017, In : Science. 356, 6339, p. 701-702 2 p.

Research output: Contribution to journalShort survey

18 Scopus citations

Cell motility resulting from spontaneous polymerization waves

Doubrovinski, K. & Kruse, K., Dec 16 2011, In : Physical Review Letters. 107, 25, 258103.

Research output: Contribution to journalArticle

55 Scopus citations

Cell-specific expression of cytosolic phosphoenolpyruvate carboxykinase in transgenic mice

Beale, E. G., Clouthier, D. E. & Hammer, R. E., Dec 1 1992, In : FASEB Journal. 6, 15, p. 3330-3337 8 p.

Research output: Contribution to journalReview article

41 Scopus citations

Chapter 5 Recent Advances on in silico ADME Modeling

Wang, J. & Hou, T., 2009, In : Annual Reports in Computational Chemistry. 5, p. 101-127 27 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of a Dazl-GFP germ cell-specific reporter

Nicholas, C. R., Xu, E. Y., Banani, S. F., Hammer, R. E., Hamra, F. K. & Reijo Pera, R. A., Jul 1 2009, In : Genesis. 47, 2, p. 74-84 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of defective nucleotide excision repair in XPC mutant mice

Cheo, D. L., Ruven, H. J. T., Meira, L. B., Hammer, R. E., Burns, D. K., Tappe, N. J., Van Zeeland, A. A., Mullenders, L. H. F. & Friedberg, E. C., Mar 4 1997, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 374, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

Characterization of flavonoids by aluminum complexation and collisionally activated dissociation

Zhang, J., Wang, J. & Brodbelt, J. S., Mar 1 2005, In : Journal of Mass Spectrometry. 40, 3, p. 350-363 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Characterization of psoriasiform and alopecic skin lesions in HLA-B27 transgenic rats

Yanagisawa, H., Richardson, J. A., Taurog, J. D. & Hammer, R. E., Jan 1 1995, In : American Journal of Pathology. 147, 4, p. 955-964 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli

Henry, L. J., Xia, D., Wilke, M. E., Deisenhofer, J. & Gerard, R. D., Aug 1994, In : Journal of virology. 68, 8, p. 5239-5246 8 p.

Research output: Contribution to journalArticle

Open Access
202 Scopus citations

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

Peterson, J. R., Bickford, L. C., Morgan, D., Kim, A. S., Ouerfelli, O., Kirschner, M. W. & Rosen, M. K., Aug 1 2004, In : Nature Structural and Molecular Biology. 11, 8, p. 747-755 9 p.

Research output: Contribution to journalArticle

138 Scopus citations

Cheminformatic Insight into the Differences between Terrestrial and Marine Originated Natural Products

Shang, J., Hu, B., Wang, J., Zhu, F., Kang, Y., Li, D., Sun, H., Kong, D. X. & Hou, T., Jun 25 2018, In : Journal of Chemical Information and Modeling. 58, 6, p. 1182-1193 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

Janetopoulos, C., Ma, L., Devreotes, P. N. & Iglesias, P. A., Jun 15 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 24, p. 8951-8956 6 p.

Research output: Contribution to journalArticle

177 Scopus citations

Chimeric muscarinic cholinergic:β-adrenergic receptors that activate G(s) in response to muscarinic agonists

Wong, S. K. F., Parker, E. M. & Ross, E. M., May 16 1990, In : Journal of Biological Chemistry. 265, 11, p. 6219-6224 6 p.

Research output: Contribution to journalArticle

176 Scopus citations

Chimeric muscarinic cholinergic:β-adrenergic receptors that are functionally promiscuous among G proteins

Wong, S. K. F. & Ross, E. M., Jul 22 1994, In : Journal of Biological Chemistry. 269, 29, p. 18968-18976 9 p.

Research output: Contribution to journalArticle

69 Scopus citations

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα

Peet, D. J., Turley, S. D., Ma, W., Janowski, B. A., Lobaccaro, J. M. A., Hammer, R. E. & Mangelsdorf, D. J., May 29 1998, In : Cell. 93, 5, p. 693-704 12 p.

Research output: Contribution to journalArticle

1134 Scopus citations

Chromophore-protein interactions and the function of the photosynthetic reaction center: A molecular dynamics study

Treutlein, H., Schulten, K., Brünger, A. T., Karplus, M., Deisenhofer, J. & Michel, H., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

Open Access
102 Scopus citations

Cleavage of pig embryos after labeling with fluorescent dyes

Pursel, V. G., Wall, R. J., Hammer, R. E. & Brinster, R. L., Dec 1985, In : Theriogenology. 24, 6, p. 693-700 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Climate change and the integrity of science

Sills, J., Gleick, P. H., Adams, R. M., Amasino, R. M., Anders, E., Anderson, D. J., Anderson, W. W., Anselin, L. E., Arroyo, M. K., Asfaw, B., Ayala, F. J., Bax, A., Bebbington, A. J., Bell, G., Bennett, M. V. L., Bennetzen, J. L., Berenbaum, M. R., Berlin, O. B., Bjorkman, P. J., Blackburn, E. & 236 others, Blamont, J. E., Botchan, M. R., Boyer, J. S., Boyle, E. A., Branton, D., Briggs, S. P., Briggs, W. R., Brill, W. J., Britten, R. J., Broecker, W. S., Brown, J. H., Brown, P. O., Brunger, A. T., Cairns, J., Canfield, D. E., Carpenter, S. R., Carrington, J. C., Cashmore, A. R., Castilla, J. C., Cazenave, A., Chapin, F. S., Ciechanover, A. J., Clapham, D. E., Clark, W. C., Clayton, R. N., Coe, M. D., Conwell, E. M., Cowling, E. B., Cowling, R. M., Cox, C. S., Croteau, R. B., Crothers, D. M., Crutzen, P. J., Daily, G. C., Dalrymple, G. B., Dangl, J. L., Darst, S. A., Davies, D. R., Davis, M. B., De Camilli, P. V., Dean, C., Defries, R. S., Deisenhofer, J., Delmer, D. P., Delong, E. F., Derosier, D. J., Diener, T. O., Dirzo, R., Dixon, J. E., Donoghue, M. J., Doolittle, R. F., Dunne, T., Ehrlich, P. R., Eisenstadt, S. N., Eisner, T., Emanuel, K. A., Englander, S. W., Ernst, W. G., Falkowski, P. G., Feher, G., Ferejohn, J. A., Fersht, A., Fischer, E. H., Fischer, R., Flannery, K. V., Frank, J., Frey, P. A., Fridovich, I., Frieden, C., Futuyma, D. J., Gardner, W. R., Garrett, C. J. R., Gilbert, W., Goldberg, R. B., Goodenough, W. H., Goodman, C. S., Goodman, M., Greengard, P., Hake, S., Hammel, G., Hanson, S., Harrison, S. C., Hart, S. R., Hartl, D. L., Haselkorn, R., Hawkes, K., Hayes, J. M., Hille, B., Hökfelt, T., House, J. S., Hout, M., Hunten, D. M., Izquierdo, I. A., Jagendorf, A. T., Janzen, D. H., Jeanloz, R., Jencks, C. S., Jury, W. A., Kaback, H. R., Kailath, T., Kay, P., Kay, S. A., Kennedy, D., Kerr, A., Kessler, R. C., Khush, G. S., Kieffer, S. W., Kirch, P. V., Kirk, K., Kivelson, M. G., Klinman, J. P., Klug, A., Knopoff, L., Kornberg, H., Kutzbach, J. E., Lagarias, J. C., Lambeck, K., Landy, A., Langmuir, C. H., Larkins, B. A., Pichon, X. T. L. E., Lenski, R. E., Leopold, E. B., Levin, S. A., Levitt, M., Likens, G. E., Lippincott-Schwartz, J., Lorand, L., Lovejoy, C. O., Lynch, M., Mabogunje, A. L., Malone, T. F., Manabe, S., Marcus, J., Massey, D. S., Mcwilliams, J. C., Medina, E., Melosh, H. J., Meltzer, D. J., Michener, C. D., Miles, E. L., Mooney, H. A., Moore, P. B., Morel, F. M. M., Mosley-Thompson, E. S., Moss, B., Munk, W. H., Myers, N., Nair, G. B., Nathans, J., Nester, E. W., Nicoll, R. A., Novick, R. P., O'Connell, J. F., Olsen, P. E., Opdyke, N. D., Oster, G. F., Ostrom, E., Pace, N. R., Paine, R. T., Palmiter, R. D., Pedlosky, J., Petsko, G. A., Pettengill, G. H., Philander, S. G., Piperno, D. R., Pollard, T. D., Price, P. B., Reichard, P. A., Reskin, B. F., Ricklefs, R. E., Rivest, R. L., Roberts, J. D., Romney, A. K., Rossmann, M. G., Russell, D. W., Rutter, W. J., Sabloff, J. A., Sagdeev, R. Z., Sahlins, M. D., Salmond, A., Sanes, J. R., Schekman, R., Schellnhuber, J., Schindler, D. W., Schmitt, J., Schneider, S. H., Schramm, V. L., Sederoff, R. R., Shatz, C. J., Sherman, F., Sidman, R. L., Sieh, K., Simons, E. L., Singer, B. H., Singer, M. F., Skyrms, B., Sleep, N. H., Smith, B. D., Snyder, S. H., Sokal, R. R., Spencer, C. S., Steitz, T. A., Strier, K. B., Südhof, T. C., Taylor, S. S., Terborgh, J., Thomas, D. H., Thompson, L. G., Tjian, R. T., Turner, M. G., Uyeda, S., Valentine, J. W., Valentine, J. S., Van Etten, J. L., Van Holde, K. E., Vaughan, M., Verba, S., Von Hippel, P. H., Wake, D. B., Walker, A., Walker, J. E., Watson, E. B., Watson, P. J., Weigel, D., Wessler, S. R., West-Eberhard, M. J., White, T. D., Wilson, W. J., Wolfenden, R. V., Wood, J. A., Woodwell, G. M., Wright, H. E., Wu, C., Wunsch, C. & Zoback, M. L., May 7 2010, In : Science. 328, 5979, p. 689-690 2 p.

Research output: Contribution to journalLetter

Open Access
102 Scopus citations

Cloning and characterization of the Dictyostelium discoideum cycloartenol synthase cDNA

Godzina, S. M., Lovato, M. A., Meyer, M. M., Foster, K. A., Wilson, W. K., Gu, W., De Hostos, E. L. & Matsuda, S. P. T., Jan 1 2000, In : Lipids. 35, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Coevolution-based inference of amino acid interactions underlying protein function

Salinas, V. H. & Ranganathan, R., Jul 19 2018, In : eLife. 7, e34300.

Research output: Contribution to journalArticle

22 Scopus citations

Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)

Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., Jan 1 1997, In : Molecular Pharmacology. 52, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor

Wlodawer, A., Deisenhofer, J. & Huber, R., Jan 5 1987, In : Journal of Molecular Biology. 193, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition

Doncic, A., Atay, O., Valk, E., Grande, A., Bush, A., Vasen, G., Colman-Lerner, A., Loog, M. & Skotheim, J. M., Mar 15 2015, In : Cell. 160, 6, p. 1182-1195 14 p.

Research output: Contribution to journalArticle

20 Scopus citations
7 Scopus citations

Compositional Control of Phase-Separated Cellular Bodies

Banani, S. F., Rice, A. M., Peeples, W. B., Lin, Y., Jain, S., Parker, R. & Rosen, M. K., Jul 28 2016, In : Cell. 166, 3, p. 651-663 13 p.

Research output: Contribution to journalArticle

237 Scopus citations

Computational Redesign of the SHV-1 β-Lactamase/β-Lactamase Inhibitor Protein Interface

Reynolds, K. A., Hanes, M. S., Thomson, J. M., Antczak, A. J., Berger, J. M., Bonomo, R. A., Kirsch, J. F. & Handel, T. M., Oct 24 2008, In : Journal of Molecular Biology. 382, 5, p. 1265-1275 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Computational systems pharmacology analysis of cannabidiol: a combination of chemogenomics-knowledgebase network analysis and integrated in silico modeling and simulation

Bian, Y. M., He, X. B., Jing, Y. K., Wang, L. R., Wang, J. M. & Xie, X. Q., Jan 1 2018, (Accepted/In press) In : Acta Pharmacologica Sinica.

Research output: Contribution to journalArticle

9 Scopus citations
6 Scopus citations

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure

Gotthardt, M., Hammer, R. E., Hübner, N., Monti, J., Witt, C. C., McNabb, M., Richardson, J. A., Granzier, H., Labeit, S. & Herz, J., Feb 21 2003, In : Journal of Biological Chemistry. 278, 8, p. 6059-6065 7 p.

Research output: Contribution to journalArticle

102 Scopus citations

Conformational analysis of peptides using Monte Carlo simulations combined with the genetic algorithm

Wang, J., Hou, T., Chen, L. & Xu, X., Jan 18 1999, In : Chemometrics and Intelligent Laboratory Systems. 45, 1-2, p. 347-351 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Conformational stabilization and crystallization of the SecA translocation ATPase from Bacillus subtilis

Weinkauf, S., Hunt, J. F., Scheuring, J., Henry, L., Fak, J., Oliver, D. B. & Deisenhofer, J., Apr 25 2001, In : Acta Crystallographica Section D: Biological Crystallography. 57, 4, p. 559-565 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

Gerber, S. H., Rah, J. C., Min, S. W., Liu, X., De Wit, H., Dulubova, I., Meyer, A. C., Rizo-Rey, J., Arancillo, M., Hammer, R. E., Verhage, M., Rosenmund, C. & Südhof, T. C., Sep 12 2008, In : Science. 321, 5895, p. 1507-1510 4 p.

Research output: Contribution to journalArticle

193 Scopus citations

Conformations and coherences in structure determination by ultrafast electron diffraction

Lin, M. M., Shorokhov, D. & Zewail, A. H., Apr 23 2009, In : Journal of Physical Chemistry A. 113, 16, p. 4075-4093 19 p.

Research output: Contribution to journalArticle

14 Scopus citations

Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

Narayanan, C., Gagné, D., Reynolds, K. A. & Doucet, N., Dec 1 2017, In : Scientific reports. 7, 1, 3207.

Research output: Contribution to journalArticle

10 Scopus citations

Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck

Banjade, S., Wu, Q., Mittal, A., Peeples, W. B., Pappu, R. V. & Rosen, M. K., Nov 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. E6426-E6435

Research output: Contribution to journalArticle

56 Scopus citations

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

Devriendt, K., Kim, A. S., Mathijs, G., Frints, S. G. M., Schwartz, M., Van Den Oord, J. J., Verhoef, G. E. G., Boogaerts, M. A., Fryns, J. P., You, D., Rosen, M. K. & Vandenberghe, P., Mar 20 2001, In : Nature genetics. 27, 3, p. 313-317 5 p.

Research output: Contribution to journalArticle

319 Scopus citations

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP

Torres, E. & Rosen, M. K., May 1 2003, In : Molecular cell. 11, 5, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

132 Scopus citations

Continuum polarizable force field within the Poisson-Boltzmann framework

Tan, Y. H., Tan, C., Wang, J. & Luo, R., Jun 26 2008, In : Journal of Physical Chemistry B. 112, 25, p. 7675-7688 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging

Sapir, A., Tsur, A., Koorman, T., Ching, K., Mishra, P., Bardenheier, A., Podolsky, L., Bening-Abu-Shach, U., Boxem, M., Chou, T. F., Broday, L. & Sternberg, P. W., Sep 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 37, p. E3880-E3889

Research output: Contribution to journalArticle

26 Scopus citations

Cooperation between elements of an organ-specific transcriptional enhancer in animals

Kruse, F., Rose, S. D., Swift, G. H., Hammer, R. E. & MacDonald, R. J., Aug 1995, In : Molecular and cellular biology. 15, 8, p. 4385-4394 10 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Cooperativity leads to temporally-correlated fluctuations in the bacteriophage lambda genetic switch

Shenker, J. Q. & Lin, M. M., Apr 8 2015, In : Frontiers in Plant Science. 6, APR, 214.

Research output: Contribution to journalArticle

2 Scopus citations

Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP

Turcotte, M., Tang, W. & Ross, E. M., Aug 2008, In : PLoS Computational Biology. 4, 8, e1000148.

Research output: Contribution to journalArticle

34 Scopus citations

Coordinating Speed and Amplitude in G-Protein Signaling

Ross, E. M., Sep 9 2008, In : Current Biology. 18, 17, p. R777-R783

Research output: Contribution to journalReview article

62 Scopus citations

Coordinating Speed and Amplitude in G-Protein Signaling (DOI:10.1016/j.cub.2008.07.035)

Ross, E. M., Dec 9 2008, In : Current Biology. 18, 23, 1 p.

Research output: Contribution to journalComment/debate

Correction: LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation

Herz, J., Clouthier, D. E. & Hammer, R. E., May 7 1993, In : Cell. 73, 3, 1 p.

Research output: Contribution to journalLetter

68 Scopus citations

Correction to Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation, [Journal of Cell Biology, 212, 5, (2016), 591-603] DOI:10.1083/jcb.201508081

Squarr, A. J., Brinkmann, K., Chen, B., Steinbacher, T., Ebnet, K., Rosen, M. K. & Bogdan, S., Mar 28 2016, In : Journal of Cell Biology. 212, 7, 1 p.

Research output: Contribution to journalComment/debate