Research Output

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

Süel, G. M., Lockless, S. W., Wall, M. A. & Ranganathan, R., Jan 1 2003, In : Nature Structural Biology. 10, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

589 Scopus citations

Evolutionarily conserved pathways of energetic connectivity in protein families

Lockless, S. W. & Ranganathan, R., Oct 8 1999, In : Science. 286, 5438, p. 295-299 5 p.

Research output: Contribution to journalArticle

927 Scopus citations

Evolutionary information for specifying a protein fold

Socolich, M., Lockless, S. W., Russ, W. P., Lee, H., Gardner, K. H. & Ranganathan, R., Sep 22 2005, In : Nature. 437, 7058, p. 512-518 7 p.

Research output: Contribution to journalReview article

283 Scopus citations

Evolutionary origins of ion channels

Ranganathan, R., 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 9, p. 3484-3486 3 p.

Research output: Contribution to journalComment/debate

Open Access
16 Scopus citations

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

Toprak, E., Veres, A., Michel, J. B., Chait, R., Hartl, D. L. & Kishony, R., Jan 1 2012, In : Nature genetics. 44, 1, p. 101-105 5 p.

Research output: Contribution to journalArticle

370 Scopus citations

Evolutionary potential of a duplicated repressor-operator pair: Simulating pathways using mutation data

Poelwijk, F. J., Kiviet, D. J. & Tans, S. J., May 1 2006, In : PLoS Computational Biology. 2, 5, p. 467-475 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Evolution-based design of proteins

Reynolds, K. A., Russ, W. P., Socolich, M. & Ranganathan, R., 2013, Methods in Protein Design. Academic Press Inc., p. 213-235 23 p. (Methods in Enzymology; vol. 523).

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations

Evolution-Based Functional Decomposition of Proteins

Rivoire, O., Reynolds, K. A. & Ranganathan, R., Jun 2016, In : PLoS Computational Biology. 12, 6, e1004817.

Research output: Contribution to journalArticle

31 Scopus citations

Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase

Stiffler, M. A., Hekstra, D. R. & Ranganathan, R., Feb 26 2015, In : Cell. 160, 5, p. 882-892 11 p.

Research output: Contribution to journalArticle

92 Scopus citations

Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats

Pierce, S. E., Wang, J., Jayawickramarajah, J., Hamilton, A. D. & Brodbelt, J. S., Oct 26 2009, In : Chemistry - A European Journal. 15, 42, p. 11244-11255 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Experience with various techniques for the refinement of protein structures

Deisenhofer, J., Remington, S. J. & Steigemann, W., Jan 1 1985, In : Methods in Enzymology. 115, C, p. 303-323 21 p.

Research output: Contribution to journalArticle

19 Scopus citations

Experimental control of pancreatic development and maintenance

Holland, A. M., Hale, M. A., Kagami, H., Hammer, R. E. & MacDonald, R. J., Sep 17 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 19, p. 12236-12241 6 p.

Research output: Contribution to journalArticle

169 Scopus citations

Experimental spondyloarthropathy in HLA-B27 transgenic rats

Taurog, J. D. & Hammer, R. E., 1996, In : Clinical Rheumatology. 15, SUPPL. 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Expression, Purification, and Characterization of Recombinant Drosophila Choline Acetyltransferase

Wu, D., Schormann, N., Lian, W., Deisenhofer, J. & Hersh, L. B., Oct 1993, In : Journal of Neurochemistry. 61, 4, p. 1416-1422 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Expression and performance in transgenic pigs.

Pursel, V. G., Bolt, D. J., Miller, K. F., Pinkert, C. A., Hammer, R. E., Palmiter, R. D. & Brinster, R. L., 1990, In : Journal of reproduction and fertility. Supplement. 40, p. 235-245 11 p.

Research output: Contribution to journalReview article

75 Scopus citations

Expression of a metallothionein-vasopressin fusion gene in transgenic mice produces hypervasopressinemia and manifestations of nephrogenic diabetes insipidus.

Habener, J. F., Cwikel, B., Hermann, H., Hammer, R. E., Palmiter, R. D. & Brinster, R. L., Dec 1 1988, In : Transactions of the Association of American Physicians. 101, p. 155-162 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

Brinster, R. L., Ritchie, K. A., Hammer, R. E., O'Brien, R. L., Arp, B. & Storb, U., Dec 1 1983, In : Nature. 306, 5941, p. 332-336 5 p.

Research output: Contribution to journalArticle

102 Scopus citations

Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy-Cataplexy in the Rat

Beuckmann, C. T., Sinton, C. M., Williams, S. C., Richardson, J. A., Hammer, R. E., Sakurai, T. & Yanagisawa, M., May 5 2004, In : Journal of Neuroscience. 24, 18, p. 4469-4477 9 p.

Research output: Contribution to journalArticle

140 Scopus citations

Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA

Chiesa, G., Johnson, D. F., Yao, Z., Innerarity, T. L., Mahley, R. W., Young, S. G., Hammer, R. E. & Hobbs, H. H., Jan 1 1993, In : Journal of Biological Chemistry. 268, 32, p. 23747-23750 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth

Hammer, R. E., Brinster, R. L., Rosenfeld, M. G., Evans, R. M. & Mayo, K. E., Dec 1 1985, In : Nature. 315, 6018, p. 413-416 4 p.

Research output: Contribution to journalArticle

174 Scopus citations

Expression of human muscarinic cholinergic receptors in tobacco

Mu, J. H., Chua, N. H. & Ross, E. M., May 1 1997, In : Plant Molecular Biology. 34, 2, p. 357-362 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Expression of human or bovine growth hormone gene with a mouse metallothionein-1 promoter in transgenic swine alters the secretion of porcine growth hormone and insulin-like growth factor-I

Miller, K. F., Bolt, D. J., Pursel, V. G., Hammer, R. E., Pinkert, C. A., Palmiter, R. D. & Brinster, R. L., 1989, In : Journal of Endocrinology. 120, 3, p. 481-488 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expression of insulin-like growth factor i in transgenic mice with elevated levels of growth hormone is correlated with growth

Mathews, L. S., Hammer, R. E., Brinster, R. L. & Palmiter, R. D., Jul 1 1988, In : Endocrinology. 123, 1, p. 433-437 5 p.

Research output: Contribution to journalArticle

138 Scopus citations

Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice

Rong, S., Cortés, V. A., Rashid, S., Anderson, N. N., McDonald, J. G., Liang, G., Moon, Y. A., Hammer, R. E. & Horton, J. D., Feb 28 2017, In : eLife. 6, e25015.

Research output: Contribution to journalArticle

39 Scopus citations

Expression of the chicken transferrin gene in transgenic mice

Stanley McKnight, G., Hammer, R. E., Kuenzel, E. A. & Brinster, R. L., Sep 1983, In : Cell. 34, 2, p. 335-341 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Expression of the poly-glutamine-ataxin-3 transgene causes loss of orexin expression: A rat model of narcolepsy

Beuckmann, C. T., Sinton, C. M., Williams, S. C., Richardson, J. A., Hammer, R. E., Sakurai, T. & Yanagisawa, M., May 1 2004, In : Sleep and Biological Rhythms. 2, SUPPL. 1, p. S44

Research output: Contribution to journalArticle

Extracellular domains of α-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels

Zhang, W., Rohlmann, A., Sargsyan, V., Aramuni, G., Hammer, R. E., Südhof, T. C. & Missler, M., Apr 27 2005, In : Journal of Neuroscience. 25, 17, p. 4330-4342 13 p.

Research output: Contribution to journalArticle

107 Scopus citations

Fast approaches for molecular polarizability calculations

Wang, J., Xie, X. Q., Hou, T. & Xu, X., May 24 2007, In : Journal of Physical Chemistry A. 111, 20, p. 4443-4448 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2

Sakakibara, I., Fujino, T., Ishii, M., Tanaka, T., Shimosawa, T., Miura, S., Zhang, W., Tokutake, Y., Yamamoto, J., Awano, M., Iwasaki, S., Motoike, T., Okamura, M., Inagaki, T., Kita, K., Ezaki, O., Naito, M., Kuwaki, T., Chohnan, S., Yamamoto, T. T. & 4 others, Hammer, R. E., Kodama, T., Yanagisawa, M. & Sakai, J., Feb 4 2009, In : Cell Metabolism. 9, 2, p. 191-202 12 p.

Research output: Contribution to journalArticle

55 Scopus citations

Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation

Squarr, A. J., Brinkmann, K., Chen, B., Steinbacher, T., Ebnet, K., Rosen, M. K. & Bogdan, S., 2016, In : Journal of Cell Biology. 212, 5, p. 591-603 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Feedforward Regulation Ensures Stability and Rapid Reversibility of a Cellular State

Doncic, A. & Skotheim, J. M., Jun 27 2013, In : Molecular cell. 50, 6, p. 856-868 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs

Cansizoglu, M. F. & Toprak, E., May 11 2017, (Accepted/In press) In : Current Genetics. p. 1-4 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Filament turnover stabilizes contractile cytoskeletal structures

Guthardt Torres, P., Doubrovinski, K. & Kruse, K., Sep 1 2010, In : EPL. 91, 6, 68003.

Research output: Contribution to journalArticle

10 Scopus citations

Filopodial dynamics and growth cone stabilization in Drosophila visual circuit development

Özel, M. N., Langen, M., Hassan, B. A. & Hiesinger, P. R., Oct 29 2015, In : eLife. 4, OCTOBER2015, e10721.

Research output: Contribution to journalArticle

26 Scopus citations

Finding a common path: Predicting gene function using inferred evolutionary trees

Reynolds, K. A., Jul 14 2014, In : Developmental Cell. 30, 1, p. 4-5 2 p.

Research output: Contribution to journalShort survey

FK506 and Rapamycin Binding to FKBP: Common Elements in Immunophilin-Ligand Complexation

Wandless, T. J., Michnick, S. W., Rosen, M. K., Karplus, M. & Schreiber, S. L., Jan 1 1991, In : Journal of the American Chemical Society. 113, 6, p. 2339-2341 3 p.

Research output: Contribution to journalArticle

32 Scopus citations

Flipping a switch

Buck, M. & Rosen, M. K., Mar 23 2001, In : Science. 291, 5512, p. 2329-2330 2 p.

Research output: Contribution to journalShort survey

11 Scopus citations

Fluidic and microfluidic tools for quantitative systems biology

Okumus, B., Yildiz, S. & Toprak, E., Feb 1 2014, In : Current Opinion in Biotechnology. 25, p. 30-38 9 p.

Research output: Contribution to journalReview article

15 Scopus citations

Force titration of amino group-terminated self-assembledmonolayers using chemical force microscopy

Zhang, H., He, H. X., Wang, J., Mu, T. & Liu, Z. F., Dec 1 1998, In : Applied Physics A: Materials Science and Processing. 66, SUPPL. 1, p. S269-S271

Research output: Contribution to journalArticle

71 Scopus citations

Force titration of self-assembled monolayer using chemical force microscopy

He, H., Li, C., Wang, J., Zhang, H., Xu, X. & Liu, Z., Dec 1 1997, In : Acta Physico - Chimica Sinica. 13, 4, p. 293-296 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Lin, Y., Protter, D. S. W., Rosen, M. K. & Parker, R., Oct 15 2015, In : Molecular cell. 60, 2, p. 208-219 12 p.

Research output: Contribution to journalArticle

505 Scopus citations

Foxj3 transcriptionally activates Mef2c and regulates adult skeletal muscle fiber type identity

Alexander, M. S., Shi, X., Voelker, K. A., Grange, R. W., Garcia, J. A., Hammer, R. E. & Garry, D. J., Jan 15 2010, In : Developmental Biology. 337, 2, p. 396-404 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Functional activation of β-adrenergic receptors by thiols in the presence or absence of agonists

Pedersen, S. E. & Ross, E. M., Dec 1 1985, In : Journal of Biological Chemistry. 260, 26, p. 14150-14157 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Functional dissection of Reelin signaling by site-directed disruption of disabled-1 adaptor binding to apolipoprotein E receptor 2: Distinct roles in development and synaptic plasticity

Beffert, U., Durudas, A., Weeber, E. J., Stolt, P. C., Giehl, K. M., Sweatt, J. D., Hammer, R. E. & Herz, J., Feb 15 2006, In : Journal of Neuroscience. 26, 7, p. 2041-2052 12 p.

Research output: Contribution to journalArticle

93 Scopus citations

Functional divergence caused by mutations in an energetic hotspot in ERK2

Taylor, C. A., Cormier, K. W., Keenan, S. E., Earnest, S., Stippec, S., Wichaidit, C., Juang, Y. C., Wang, J., Shvartsman, S. Y., Goldsmith, E. J. & Cobb, M. H., Jul 30 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 31, p. 15514-15523 10 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Functional domains in the β-adrenergic receptor

Ross, E. M., Wong, S. K. F., Rubenstein, R. C. & Higashijima, T., 1988, In : Cold Spring Harbor symposia on quantitative biology. 53, 1, p. 499-506 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
Open Access
238 Scopus citations

Functional importance of the amino terminus of G

Hepler, J. R., Biddlecome, G. H., Kleuss, C., Camp, L. A., Hofmann, S. L., Ross, E. M. & Gilman, A. G., Jan 5 1996, In : Journal of Biological Chemistry. 271, 1, p. 496-504 9 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations
Open Access
57 Scopus citations