Fingerprint Dive into the research topics where IC-Lab Orchard is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Norovirus Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Immunologic Receptors Medicine & Life Sciences
Caliciviridae Infections Medicine & Life Sciences
Quaternary Protein Structure Medicine & Life Sciences
Viral Nonstructural Proteins Medicine & Life Sciences
Molecular Docking Simulation Medicine & Life Sciences
Virus Receptors Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Robert Orchard
20112019

Research Output 2018 2019

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

Lee, S., Liu, H., Wilen, C. B., Sychev, Z. E., Desai, C., Hykes, B. L., Orchard, R. C., McCune, B. T., Kim, K. W., Nice, T. J., Handley, S. A., Baldridge, M. T., Amarasinghe, G. K. & Virgin, H. W., Jun 12 2019, In : Cell Host and Microbe. 25, 6, p. 845-857.e5

Research output: Contribution to journalArticle

Viral Nonstructural Proteins
Norovirus
Vaccines
Enterovirus
Vaccination

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

Orvedahl, A., McAllaster, M. R., Sansone, A., Dunlap, B. F., Desai, C., Wang, Y. T., Balce, D. R., Luke, C. J., Lee, S., Orchard, R. C., Artyomov, M. N., Handley, S. A., Doench, J. G., Silverman, G. A. & Virgin, H. W., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 33, p. 16497-16506 10 p.

Research output: Contribution to journalArticle

Open Access
Autophagy
Myeloid Cells
Shock
Cell Death
Tumor Necrosis Factor-alpha

Identification of antinorovirus genes in human cells using genome-wide CRISPR activation screening

Orchard, R. C., Sullender, M. E., Dunlap, B. F., Balce, D. R., Doench, J. G. & Virgin, H. W., Jan 1 2019, In : Journal of virology. 93, 1, e01324-18.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Norovirus
virology
Virology
Genome