Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2023
Characterizing inflammatory profiles of suicidal behavior in adolescents: Rationale and design
Chin Fatt, C., Ayvaci, E. R., Jha, M. K., Emslie, G., Gibson, S., Minhajuddin, A. T., Mayes, T. L., Farrar, J. D. & Trivedi, M. H., Mar 15 2023, In: Journal of affective disorders. 325, p. 55-61 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of norepinephrine on immunity and oxidative metabolism in sepsis
Thoppil, J., Mehta, P., Bartels, B., Sharma, D. & Farrar, J. D., 2023, In: Frontiers in immunology. 14, 1271098.Research output: Contribution to journal › Short survey › peer-review
Open Access1 Scopus citations -
2022
Adrenergic signaling controls early transcriptional programs during CD8+ T cell responses to viral infection
Estrada, L. D., Cobanoglu, D. A., Wise, A., Maples, R. W., Cobanoglu, M. C. & David Farrar, J., Aug 2022, In: PloS one. 17, 8 August, e0272017.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Immune characterization of suicidal behavior in female adolescents
Chin Fatt, C. R., Farrar, J. D., Jha, M. K., Minhajuddin, A., Mayes, T., Foster, J. A. & Trivedi, M. H., Nov 2022, In: Brain, Behavior, and Immunity - Health. 25, 100499.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2021
Humoral and cellular correlates of a novel immune-related adverse event and its treatment
Gonugunta, A. S., Von Itzstein, M. S., Mu-Mosley, H., Fattah, F., Farrar, J. D., Mobely, A., Rashdan, S., Lai, S., Bhai, S. F., Bermas, B. L., Karp, D., Li, Q. Z., Wakeland, E. K. & Gerber, D. E., Dec 8 2021, In: Journal for ImmunoTherapy of Cancer. 9, 12, e003585.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2020
Adrenergic regulation of immune cell function and inflammation
Sharma, D. & Farrar, J. D., Dec 2020, In: Seminars in Immunopathology. 42, 6, p. 709-717 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access74 Scopus citations -
Does negative pressure wound therapy with irrigation improve clinical outcomes? A randomized clinical trial in patients with diabetic foot infections
Lavery, L. A., Davis, K. E., La Fontaine, J., Farrar, J. D., Bhavan, K., Oz, O. K. & Crisologo, P. A., Oct 2020, In: American journal of surgery. 220, 4, p. 1076-1082 7 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
IgE-mediated regulation of IL-10 and type I IFN enhances rhinovirus-induced Th2 differentiation by primary human monocytes
Rowe, R. K., Pyle, D. M., Farrar, J. D. & Gill, M. A., Oct 1 2020, In: European Journal of Immunology. 50, 10, p. 1550-1559 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Lyopreserved amniotic membrane is cellularly and clinically similar to cryopreserved construct for treating foot ulcers
Davis, K. E., Killeen, A. L., Farrar, D., Raspovic, K. M., Berriman-Rozen, Z. D., Malone, M. & Lavery, L. A., Dec 2020, In: International Wound Journal. 17, 6, p. 1893-1901 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Neuro-immune interactions
Farrar, J. D., Dec 2020, In: Seminars in Immunopathology. 42, 6, p. 667-668 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access2 Scopus citations -
Randomized clinical study to compare negative pressure wound therapy with simultaneous saline irrigation and traditional negative pressure wound therapy for complex foot infections
Davis, K. E., La Fontaine, J., Farrar, D., Oz, O. K., Crisologo, P. A., Berriman, S. & Lavery, L. A., Jan 1 2020, In: Wound Repair and Regeneration. 28, 1, p. 97-104 8 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
The effect of continuous diffusion of oxygen treatment on cytokines, perfusion, bacterial load, and healing in patients with diabetic foot ulcers
Lavery, L. A., Killeen, A. L., Farrar, D., Akgul, Y., Crisologo, P. A., Malone, M. & Davis, K. E., Dec 2020, In: International Wound Journal. 17, 6, p. 1986-1995 10 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
The infected diabetic foot: Can serum biomarkers predict osteomyelitis after hospital discharge for diabetic foot infections?
Crisologo, P. A., Davis, K. E., Ahn, J., Farrar, D., Van Asten, S., La Fontaine, J. & Lavery, L. A., Sep 1 2020, In: Wound Repair and Regeneration. 28, 5, p. 617-622 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Type I interferon suppresses memory Th2 cell cytokine secretion from allergic subjects
Chen, F., Rowe, R. K., Gill, M. A. & Farrar, J. D., Mar 1 2020, In: Allergy: European Journal of Allergy and Clinical Immunology. 75, 3, p. 695-698 4 p.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
2018
Adrenergic signaling at the interface of allergic asthma and viral infections
Agaç, D., Gill, M. A. & Farrar, J. D., Apr 11 2018, In: Frontiers in immunology. 9, APR, 736.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
The β2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion
Ağaç, D., Estrada, L. D., Maples, R., Hooper, L. V. & Farrar, J. D., Nov 2018, In: Brain, Behavior, and Immunity. 74, p. 176-185 10 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
2016
Cutting Edge: Critical role of glycolysis in human plasmacytoid dendritic cell antiviral responses
Bajwa, G., DeBerardinis, R. J., Shao, B., Hall, B., Farrar, J. D. & Gill, M. A., Mar 1 2016, In: Journal of Immunology. 196, 5, p. 2004-2009 6 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Scopus citations -
STAT4-mediated transcriptional repression of the IL5 gene in human memory Th2 cells
Gonzales-van Horn, S. R., Estrada, L. D., van Oers, N. S. C. & Farrar, J. D., Jun 1 2016, In: European Journal of Immunology. 46, 6, p. 1504-1510 7 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8+ T-cell effector function
Estrada, L. D., Ağaç, D. & Farrar, J. D., Aug 1 2016, In: European Journal of Immunology. 46, 8, p. 1948-1958 11 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2015
Housing temperature-induced stress is suppressing murine Graft-versus-host disease through β2-adrenergic receptor signaling
Leigh, N. D., Kokolus, K. M., O'Neill, R. E., Du, W., Eng, J. W. L., Qiu, J., Chen, G. L., McCarthy, P. L., Farrar, J. D., Cao, X. & Repasky, E. A., Nov 15 2015, In: Journal of Immunology. 195, 10, p. 5045-5054 10 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Interferon at the crossroads of allergy and viral infections
Gonzales-van Horn, S. R. & David Farrar, J., Aug 1 2015, In: Journal of Leukocyte Biology. 98, 2, p. 185-194 10 p.Research output: Contribution to journal › Review article › peer-review
66 Scopus citations -
2014
IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells
Huber, J. P., Gonzales-Van Horn, S. R., Roybal, K. T., Gill, M. A. & Farrar, J. D., Jun 15 2014, In: Journal of Immunology. 192, 12, p. 5687-5694 8 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Pharmacological inhibition of TPL2/MAP3K8 blocks human cytotoxic T lymphocyte effector functions
Chowdhury, F. Z., Estrada, L. D., Murray, S., Forman, J. & Farrar, J. D., Mar 18 2014, In: PloS one. 9, 3, e92187.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
2013
IgE cross-linking critically impairs human monocyte function by blocking phagocytosis
Pyle, D. M., Yang, V. S., Gruchalla, R. S., Farrar, J. D. & Gill, M. A., Feb 2013, In: Journal of Allergy and Clinical Immunology. 131, 2, p. 491-500.e5Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature
Becker, A. M., Dao, K. H., Han, B. K., Kornu, R., Lakhanpal, S., Mobley, A. B., Li, Q. Z., Lian, Y., Wu, T., Reimold, A. M., Olsen, N. J., Karp, D. R., Chowdhury, F. Z., Farrar, J. D., Satterthwaite, A. B., Mohan, C., Lipsky, P. E., Wakeland, E. K. & Davis, L. S., Jun 24 2013, In: PloS one. 8, 6, e67003.Research output: Contribution to journal › Article › peer-review
150 Scopus citations -
2011
IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo
Chowdhury, F. Z., Ramos, H. J., Davis, L. S., Forman, J. & Farrar, J. D., Oct 6 2011, In: Blood. 118, 14, p. 3890-3900 11 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Regulation of effector and memory T-cell functions by type I interferon
Huber, J. P. & David Farrar, J., Apr 2011, In: Immunology. 132, 4, p. 466-474 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access189 Scopus citations -
2010
Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3
Huber, J. P., Ramos, H. J., Gill, M. A. & Farrar, J. D., Jul 15 2010, In: Journal of Immunology. 185, 2, p. 813-817 5 p.Research output: Contribution to journal › Article › peer-review
113 Scopus citations -
2009
Reciprocal responsiveness to interleukin-12 and interferon-α specifies human CD8+ effector versus central memory T-cell fates
Ramos, H. J., Davis, A. M., Cole, A. G., Schatzle, J. D., Forman, J. & Farrar, J. D., 2009, In: Blood. 113, 22, p. 5516-5525 10 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
2008
Blockade of virus infection by human CD4+ T cells via a cytokine relay network
Davis, A. M., Hagan, K. A., Matthews, L. A., Bajwa, G., Gill, M. A., Gale, M. & Farrar, J. D., 2008, In: Journal of Immunology. 180, 10, p. 6923-6932 10 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Cutting edge: A T-bet-independent role for IFN-α/β in regulating IL-2 secretion in human CD4+ central memory T cells
Davis, A. M., Ramos, H. J., Davis, L. S. & David Farrar, J., Dec 15 2008, In: Journal of Immunology. 181, 12, p. 8204-8208 5 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-κB, is dispensable for T cell development and/or T cell effector functions
Young, J. A., Becker, A. M., Medeiros, J. J., Shapiro, V. S., Wang, A., Farrar, J. D., Quill, T. A., van Huijsduijnen, R. H. & van Oers, N. S. C., Aug 2008, In: Molecular Immunology. 45, 14, p. 3756-3766 11 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2007
IFN-α is not sufficient to drive Th1 development due to lack of stable T-bet expression
Ramos, H. J., Davis, A. M., George, T. C. & Farrar, J. D., Sep 15 2007, In: Journal of Immunology. 179, 6, p. 3792-3803 12 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Pre-assembly of STAT4 with the human IFN-α/β receptor-2 subunit is mediated by the STAT4 N-domain
Tyler, D. R., Persky, M. E., Matthews, L. A., Chan, S. & Farrar, J. D., Mar 2007, In: Molecular Immunology. 44, 8, p. 1864-1872 9 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2006
Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-α
Berenson, L. S., Gavrieli, M., Farrar, J. D., Murphy, T. L. & Murphy, K. M., Oct 15 2006, In: Journal of Immunology. 177, 8, p. 5195-5203 9 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2005
IL-12, but not IFN-α, promotes STAT4 activation and Th1 development in murine CD4+ T cells expressing a chimeric murine/human Stat2 gene
Persky, M. E., Murphy, K. M. & Farrar, J. D., Jan 1 2005, In: Journal of Immunology. 174, 1, p. 294-301 8 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2004
Frontline: Absence of functional STAT4 activation despite detectable tyrosine phosphorylation induced by murine IFN-α
Berenson, L. S., Farrar, J. D., Murphy, T. L. & Murphy, K. M., Sep 2004, In: European Journal of Immunology. 34, 9, p. 2365-2374 10 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
2002
T helper subset development: Roles of instruction, selection, and transcription
David Farrar, J., Asnagli, H. & Murphy, K. M., 2002, In: Journal of Clinical Investigation. 109, 4, p. 431-435 5 p.Research output: Contribution to journal › Review article › peer-review
142 Scopus citations -
2001
An instructive component in T helper cell type 2 (Th2) development mediated by GATA-3
David Farrar, J., Ouyang, W., Löhning, M., Assenmacher, M., Radbruch, A., Kanagawa, O. & Murphy, K. M., Mar 5 2001, In: Journal of Experimental Medicine. 193, 5, p. 643-649 7 p.Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
2000
Recruitment of Stat4 to the human interferon-α/β receptor requires activated Stat2
Farrar, J. D., Smith, J. D., Murphy, T. L. & Murphy, K. M., Jan 28 2000, In: Journal of Biological Chemistry. 275, 4, p. 2693-2697 5 p.Research output: Contribution to journal › Article › peer-review
91 Scopus citations -
Role of the Stat4 N domain in receptor proximal tyrosine phosphorylation
Murphy, T. L., Geissal, E. D., Farrar, J. D. & Murphy, K. M., 2000, In: Molecular and cellular biology. 20, 19, p. 7121-7131 11 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
Farrar, J. D., Smith, J. D., Murphy, T. L., Leung, S., Stark, G. R. & Murphy, K. M., Jul 2000, In: Nature immunology. 1, 1, p. 65-69 5 p.Research output: Contribution to journal › Article › peer-review
154 Scopus citations -
Signaling and transcription in T helper development
Murphy, K. M., Ouyang, W., Farrar, J. D., Yang, J., Ranganath, S., Asnagli, H., Afkarian, M. & Murphy, T. L., 2000, In: Annual review of immunology. 18, p. 451-494 44 p.Research output: Contribution to journal › Review article › peer-review
554 Scopus citations -
Type I interferons and T helper development
Farrar, J. D. & Murphy, K. M., 2000, In: Immunology Today. 21, 10, p. 484-489 6 p.Research output: Contribution to journal › Comment/debate › peer-review
96 Scopus citations -
1999
Cancer dormancy. VII. A regulatory role for CD8+ T cells and IFN-γ in establishing and maintaining the tumor-dormant state
Farrar, J. D., Katz, K. H., Windsor, J., Thrush, G., Scheuermann, R. H., Uhr, J. W. & Street, N. E., Mar 1 1999, In: Journal of Immunology. 162, 5, p. 2842-2849 8 p.Research output: Contribution to journal › Article › peer-review
140 Scopus citations -
Molecular mechanisms in T helper phenotype development
Farrar, J. D., Ranganath, S. H. & Murphy, K. M., Jan 1 1999, In: Springer Seminars in Immunopathology. 21, 3, p. 211-230 20 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
1996
Regulation of tumor dormancy by cd4+ and cd8+ t cell subpopulations
David Farrar, J., Katz, K. S., Windsor, J. L., Jonathan, W. & Street, U. N. E., 1996, In: FASEB Journal. 10, 6, p. A1444Research output: Contribution to journal › Article › peer-review
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1995
A synthetic standard DNA construct for use in quantification of murine cytokine mRNA molecules
David Farrar, J. & Street, N. E., Sep 1995, In: Molecular Immunology. 32, 13, p. 991-1000 10 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
1993
Defective mannosylation of glycosylphosphatidylinositol in Lec35 Chinese hamster ovary cells
Camp, L. A., Chauhan, P., Farrar, J. D. & Lehrman, M. A., Mar 25 1993, In: Journal of Biological Chemistry. 268, 9, p. 6721-6728 8 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
1992
Differential temporal and spatial expression of mRNA encoding extracellular matrix components in decidua during the peri-implantation period
Farrar, J. D. & Carson, D. D., 1992, In: Biology of reproduction. 46, 6, p. 1095-1108 14 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations