Research output per year
Research output per year
- 1 - 50 out of 114 results
Search results
-
2023
An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut-resident plasma cells
Ceglia, S., Berthelette, A., Howley, K., Li, Y., Mortzfeld, B., Bhattarai, S. K., Yiew, N. K. H., Xu, Y., Brink, R., Cyster, J. G., Hooper, L. V., Randolph, G. J., Bucci, V. & Reboldi, A., Mar 2023, In: Nature immunology. 24, 3, p. 531-544 14 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Macrophages regulate gastrointestinal motility through complement component 1q
Pendse, M., De Selle, H., Vo, N., Quinn, G., Dende, C., Li, Y., Salinas, C. N., Srinivasan, T., Propheter, D. C., Crofts, A. A., Koo, E., Hassell, B., Ruhn, K. A., Raj, P., Obata, Y. & Hooper, L. V., Apr 2023, In: eLife. 12, e78558.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2022
Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cells
Carroll, D. J., Burns, M. W. N., Mottram, L., Propheter, D. C., Boucher, A., Lessen, G. M., Kumar, A., Malaker, S. A., Xing, C., Hooper, L. V., Yrlid, U. & Kohler, J. J., Feb 1 2022, In: Journal of Biological Chemistry. 298, 2, 101463.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2021
Impact of Bead-Beating Intensity on the Genus- and Species-Level Characterization of the Gut Microbiome Using Amplicon and Complete 16S rRNA Gene Sequencing
Zhang, B., Brock, M., Arana, C., Dende, C., van Oers, N. S., Hooper, L. V. & Raj, P., Oct 1 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 678522.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Serum amyloid a delivers retinol to intestinal myeloid cells to promote adaptive immunity
Bang, Y. J., Hu, Z., Li, Y., Gattu, S., Ruhn, K. A., Raj, P., Herz, J. & Hooper, L. V., Sep 17 2021, In: Science. 373, 6561, eabf9232.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Small proline-rich protein 2A is a gut bactericidal protein deployed during helminth infection
Hu, Z., Zhang, C., Sifuentes-Dominguez, L., Zarek, C. M., Propheter, D. C., Kuang, Z., Wang, Y., Pendse, M., Ruhn, K. A., Hassell, B., Behrendt, C. L., Zhang, B., Raj, P., Harris-Tryon, T. A., Reese, T. A. & Hooper, L. V., Nov 5 2021, In: Science. 374, 6568, eabe6723.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2019
Epithelial retinoic acid receptor β regulates serum amyloid A expression and Vitamin A-dependent intestinal immunity
Gattu, S., Bang, Y. J., Pendse, M., Dende, C., Chara, A. L., Harris, T. A., Wang, Y., Ruhn, K. A., Kuang, Z., Sockanathan, S. & Hooper, L. V., May 28 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 166, 22, p. 10911-10916 6 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Immune control of the microbiota prevents obesity
Wang, Y. & Hooper, L. V., Jul 26 2019, In: Science (New York, N.Y.). 365, 6451, p. 316-317 2 p.Research output: Contribution to journal › Comment/debate › peer-review
17 Scopus citations -
Molecular basis for retinol binding by serum amyloid A during infection
Hu, Z., Bang, Y. J., Ruhn, K. A. & Hooper, L. V., Sep 17 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 38, p. 19077-19082 6 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin
Harris, T. A., Gattu, S., Propheter, D. C., Kuang, Z., Bel, S., Ruhn, K. A., Chara, A. L., Edwards, M., Zhang, C., Jo, J. H., Raj, P., Zouboulis, C. C., Kong, H. H., Segre, J. A. & Hooper, L. V., Jun 12 2019, In: Cell Host and Microbe. 25, 6, p. 777-788.e8Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3
Kuang, Z., Wang, Y., Li, Y., Ye, C., Ruhn, K. A., Behrendt, C. L., Olson, E. N. & Hooper, L. V., Sep 27 2019, In: Science. 365, 6460, p. 1428-1434 7 p.Research output: Contribution to journal › Article › peer-review
Open Access188 Scopus citations -
2018
Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth
Gillis, C. C., Hughes, E. R., Spiga, L., Winter, M. G., Zhu, W., Furtado de Carvalho, T., Chanin, R. B., Behrendt, C. L., Hooper, L. V., Santos, R. L. & Winter, S. E., Jan 10 2018, In: Cell Host and Microbe. 23, 1, p. 54-64.e6Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Erratum: Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth (Cell Host & Microbe (2018) 23(1) (54–64.e6) (S1931312817305000) (10.1016/j.chom.2017.11.006))
Gillis, C. C., Hughes, E. R., Spiga, L., Winter, M. G., Zhu, W., Furtado de Carvalho, T., Chanin, R. B., Behrendt, C. L., Hooper, L. V., Santos, R. L. & Winter, S. E., Apr 11 2018, In: Cell Host and Microbe. 23, 4, p. 570 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access19 Scopus citations -
Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
Burger, E., Araujo, A., López-Yglesias, A., Rajala, M. W., Geng, L., Levine, B., Hooper, L. V., Burstein, E. & Yarovinsky, F., Feb 14 2018, In: Cell Host and Microbe. 23, 2, p. 177-190.e4Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Murine colitis reveals a disease-associated bacteriophage community
Duerkop, B. A., Kleiner, M., Paez-Espino, D., Zhu, W., Bushnell, B., Hassell, B., Winter, S. E., Kyrpides, N. C. & Hooper, L. V., Sep 1 2018, In: Nature microbiology. 3, 9, p. 1023-1031 9 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
Precision editing of the gut microbiota ameliorates colitis
Zhu, W., Winter, M. G., Byndloss, M. X., Spiga, L., Duerkop, B. A., Hughes, E. R., Büttner, L., De Lima Romão, E., Behrendt, C. L., Lopez, C. A., Sifuentes-Dominguez, L., Huff-Hardy, K., Wilson, R. P., Gillis, C. C., Tükel, Ç., Koh, A. Y., Burstein, E., Hooper, L. V., Bäumler, A. J. & Winter, S. E., Jan 11 2018, In: Nature. 553, 7687, p. 208-211 4 p.Research output: Contribution to journal › Article › peer-review
Open Access361 Scopus citations -
Secretory autophagy of lysozyme in Paneth cells
Bel, S. & Hooper, L. V., Apr 3 2018, In: Autophagy. 14, 4, p. 719-721 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access31 Scopus citations -
Stress response factors drive regrowth of quiescent cells
Kuang, Z., Ji, H. & Boeke, J. D., Aug 1 2018, In: Current Genetics. 64, 4, p. 807-810 4 p.Research output: Contribution to journal › Review article › peer-review
9 Scopus citations -
Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease
Zhao, D., Kim, Y. H., Jeong, S., Greenson, J. K., Chaudhry, M. S., Hoepting, M., Anderson, E. R., van den Brink, M. R., Peled, J. U., Gomes, A. L., Slingerland, A. E., Donovan, M. J., Harris, A. C., Levine, J. E., Ozbek, U., Hooper, L. V., Stappenbeck, T. S., Ver Heul, A., Liu, T. C., Reddy, P., & 1 others, Nov 1 2018, In: Journal of Clinical Investigation. 128, 11, p. 4970-4979 10 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations -
The β2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion
Ağaç, D., Estrada, L. D., Maples, R., Hooper, L. V. & Farrar, J. D., Nov 2018, In: Brain, Behavior, and Immunity. 74, p. 176-185 10 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
2017
An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate
Spiga, L., Winter, M. G., Furtado de Carvalho, T., Zhu, W., Hughes, E. R., Gillis, C. C., Behrendt, C. L., Kim, J., Chessa, D., Andrews-Polymenis, H. L., Beiting, D. P., Santos, R. L., Hooper, L. V. & Winter, S. E., Sep 13 2017, In: Cell Host and Microbe. 22, 3, p. 291-301.e6Research output: Contribution to journal › Article › peer-review
Open Access98 Scopus citations -
IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice
Choi, J. H., Wang, K. W., Zhang Ph.D., D-W., Zhan, X., Wang, T., Bu, C. H., Behrendt, C. L., Zeng, M., Wang, Y., Misawa, T., Li, X., Tang, M., Zhan, X., Scott, L., Hildebrand, S., Murray, A. R., Moresco, E. M. Y., Hooper, L. V. & Beutler, B. A., Feb 14 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. E1196-E1204Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis
Hughes, E. R., Winter, M. G., Duerkop, B. A., Spiga, L., Furtado de Carvalho, T., Zhu, W., Gillis, C. C., Büttner, L., Smoot, M. P., Behrendt, C. L., Cherry, S., Santos, R. L., Hooper, L. V. & Winter, S. E., Feb 8 2017, In: Cell Host and Microbe. 21, 2, p. 208-219 12 p.Research output: Contribution to journal › Article › peer-review
Open Access213 Scopus citations -
NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways
Udden, S. M. N., Peng, L., Gan, J. L., Shelton, J. M., Malter, J. S., Hooper, L. V. & Zaki, M. H., Jun 27 2017, In: Cell Reports. 19, 13, p. 2756-2770 15 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
Bel, S., Pendse, M., Wang, Y., Ii, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J. & Hooper, L. V., Sep 8 2017, In: Science. 357, 6355, p. 1047-1052 6 p.Research output: Contribution to journal › Article › peer-review
Open Access248 Scopus citations -
Resistin-like molecule β is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium
Propheter, D. C., Chara, A. L., Harris, T. A., Ruhn, K. A. & Hooper, L. V., Oct 17 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, p. 11027-11033 7 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
The intestinal microbiota regulates body composition through NFIL3 and the circadian clock
Wang, Y., Kuang, Z., Yu, X., Ruhn, K. A., Kubo, M. & Hooper, L. V., Sep 1 2017, In: Science. 357, 6354, p. 912-916 5 p.Research output: Contribution to journal › Article › peer-review
Open Access289 Scopus citations -
2016
Bacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales species
Chatzidaki-Livanis, M., Geva-Zatorsky, N., Comstock, L. E. & Hooper, L. V., Mar 29 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 13, p. 3627-3632 6 p.Research output: Contribution to journal › Article › peer-review
Open Access142 Scopus citations -
Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation
Wang, L., Fouts, D. E., Stärkel, P., Hartmann, P., Chen, P., Llorente, C., DePew, J., Moncera, K., Ho, S. B., Brenner, D. A., Hooper, L. V. & Schnabl, B., 2016, In: Cell Host and Microbe. 19, 2, p. 227-239 13 p.Research output: Contribution to journal › Article › peer-review
Open Access265 Scopus citations -
Molecular basis for lytic bacteriophage resistance in enterococci
Duerkop, B. A., Huo, W., Bhardwaj, P., Palmer, K. L. & Hooper, L. V., Jul 1 2016, In: mBio. 7, 4, e01304-16.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
Mum's microbes boost baby's immunity
Pendse, M. & Hooper, L. V., May 5 2016, In: Nature. 533, 7601, p. 42-43 2 p.Research output: Contribution to journal › Short survey › peer-review
Open Access7 Scopus citations -
Pulmonary Th17 antifungal immunity is regulated by the gut microbiome
McAleer, J. P., Nguyen, N. L. H., Chen, K., Kumar, P., Ricks, D. M., Binnie, M., Armentrout, R. A., Pociask, D. A., Hein, A., Yu, A., Vikram, A., Bibby, K., Umesaki, Y., Rivera, A., Sheppard, D., Ouyang, W., Hooper, L. V. & Kolls, J. K., Jul 1 2016, In: Journal of Immunology. 197, 1, p. 97-107 11 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations -
2015
Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization
Fan, D., Coughlin, L. A., Neubauer, M. M., Kim, J., Kim, M. S., Zhan, X., Simms-Waldrip, T. R., Xie, Y., Hooper, L. V. & Koh, A., Jul 9 2015, In: Nature medicine. 21, 7, p. 808-814 7 p.Research output: Contribution to journal › Review article › peer-review
299 Scopus citations -
Antimicrobial Defense of the Intestine
Mukherjee, S. & Hooper, L. V., Jan 20 2015, In: Immunity. 42, 1, p. 28-39 12 p.Research output: Contribution to journal › Review article › peer-review
222 Scopus citations -
Bacteria Come into Focus: New Tools for Visualizing the Microbiota
Propheter, D. C. & Hooper, L. V., Oct 14 2015, In: Cell Host and Microbe. 18, 4, p. 392-394 3 p., 1348.Research output: Contribution to journal › Short survey › peer-review
Open Access10 Scopus citations -
Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis
Lopez-Medina, E., Fan, D., Coughlin, L. A., Ho, E. X., Lamont, I. L., Reimmann, C., Hooper, L. V. & Koh, A. Y., Aug 1 2015, In: PLoS pathogens. 11, 8, e1005129.Research output: Contribution to journal › Article › peer-review
Open Access94 Scopus citations -
Cutting edge: Developmental regulation of IFN-γ production by mouse neutrophil precursor cells
Sturge, C. R., Burger, E., Raetz, M., Hooper, L. V. & Yarovinsky, F., Jul 1 2015, In: Journal of Immunology. 195, 1, p. 36-40 5 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Epithelial Cell Contributions to Intestinal Immunity
Hooper, L. V., 2015, In: Advances in Immunology. 126, p. 129-172 44 p.Research output: Contribution to journal › Article › peer-review
93 Scopus citations -
Erratum: Immune adaptations that maintain homeostasis with the intestinal microbiota (Nature Reviews Immunology (2010) 10 159-169))
Hooper, L. V. & Macpherson, A. J., Apr 24 2015, In: Nature Reviews Immunology. 15, 5, p. 329 1 p.Research output: Contribution to journal › Comment/debate › peer-review
5 Scopus citations -
Evaluation of methods to purify virus-like particles for metagenomic sequencing of intestinal viromes
Kleiner, M., Hooper, L. V. & Duerkop, B. A., Jan 22 2015, In: BMC Genomics. 16, 1, 7.Research output: Contribution to journal › Article › peer-review
132 Scopus citations -
Immunology: A bacterial nudge to T-cell function
Bel, S. & Hooper, L. V., Oct 15 2015, In: Nature. 526, 7573, p. 328-330 3 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense
Hu, S., Peng, L., Kwak, Y. T., Tekippe, E. M., Pasare, C., Malter, J. S., Hooper, L. V. & Zaki, M. H., Dec 1 2015, In: Cell Reports. 13, 9, p. 1922-1936 15 p.Research output: Contribution to journal › Article › peer-review
Open Access92 Scopus citations -
2014
Antibacterial membrane attack by a pore-forming intestinal C-type lectin
Mukherjee, S., Zheng, H., Derebe, M. G., Callenberg, K. M., Partch, C. L., Rollins, D., Propheter, D. C., Rizo-Rey, J., Grabe, M., Jiang, Q. X. & Hooper, L. V., 2014, In: Nature. 505, 7481, p. 103-107 5 p.Research output: Contribution to journal › Article › peer-review
236 Scopus citations -
Innate lymphoid cells sweeten the pot: Immune cells prompt gut epithelial cells to produce carbohydrate nutrients for resident bacteria
Hooper, L. V., Sep 12 2014, In: Science. 345, 6202, p. 1248-1249 2 p.Research output: Contribution to journal › Comment/debate › peer-review
3 Scopus citations -
Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection
Derebe, M. G., Zlatkov, C. M., Gattu, S., Ruhn, K. A., Vaishnava, S., Diehl, G. E., MacMillan, J. B., Williams, N. S. & Hooper, L. V., Jul 29 2014, In: eLife. 3, July2014, p. 1-18 18 p., e03206.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor
Yu, X., Wang, Y., Deng Ph.D., M., Li, Y., Ruhn, K. A., Zhang, C. & Hooper, L. V., Oct 13 2014, In: eLife. 3, e04406.Research output: Contribution to journal › Article › peer-review
Open Access188 Scopus citations -
2013
Intestinal epithelial autophagy is essential for host defense against invasive bacteria
Benjamin, J. L., Sumpter, R., Levine, B. & Hooper, L. V., Jun 12 2013, In: Cell Host and Microbe. 13, 6, p. 723-734 12 p.Research output: Contribution to journal › Article › peer-review
243 Scopus citations -
Mei-P26 Cooperates with Bam, Bgcn and Sxl to Promote Early Germline Development in the Drosophila Ovary
Li, Y., Zhang, Q., Carreira-Rosario, A., Maines, J. Z., McKearin, D. M. & Buszczak, M., Mar 20 2013, In: PloS one. 8, 3, e58301.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Parasite-induced T H 1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells
Raetz, M., Hwang, S. H., Wilhelm, C. L., Kirkland, D., Benson, A., Sturge, C. R., Mirpuri, J., Vaishnava, S., Hou, B., Defranco, A. L., Gilpin, C. J., Hooper, L. V. & Yarovinsky, F., Feb 2013, In: Nature immunology. 14, 2, p. 136-142 7 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations -
Proteobacteria-specific IgA regulates maturation of the intestinal microbiota
Mirpuri, J., Raetz, M., Sturge, C. R., Wilhelm, C. L., Benson, A., Savani, R. C., Hooper, L. V. & Yarovinsky, F., Sep 25 2013, In: Gut Microbes. 5, 1, p. 28-39 12 p.Research output: Contribution to journal › Article › peer-review
Open Access198 Scopus citations