Immunology - Van Oers Lab - Administration

Research Output

1995

Syk mutation in Jurkat E6-derived clones results in lack of p72(syk) expression

Fargnoli, J., Burkhardt, A. L., Laverty, M., Kut, S. A., Van Oers, N. S. C., Weiss, A. & Bolen, J. B., Jan 1 1995, In : Journal of Biological Chemistry. 270, 44, p. 26533-26537 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit

Van Oers, N. S. C., Von Boehmer, H. & Weiss, A., Nov 1 1995, In : Journal of Experimental Medicine. 182, 5, p. 1585-1590 6 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations

The syk/zap-70 protein tyrosine kinase connection to antigen receptor signalling processes

Van Oers, N. S. C. & Weiss, A., Jan 1 1995, In : Seminars in Immunology. 7, 4, p. 227-236 10 p.

Research output: Contribution to journalArticle

69 Scopus citations
1994

Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling

Chan, A. C., Van Oers A, N. S. C., Tran, A., Turka, L., Law, C. L., Ryan, J. C., Clark, E. A. & Weiss, A., May 15 1994, In : Journal of Immunology. 152, 10, p. 4758-4766 9 p.

Research output: Contribution to journalArticle

224 Scopus citations

Molecular and genetic insights into T cell antigen receptor signal transduction

Weiss, A., Iwashima, M., Irving, B., Van Oers, N. S. C., Kadlecek, T. A., Straus, D. & Chan, A., Jan 1 1994, In : Advances in experimental medicine and biology. 365, p. 53-62 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Production and characterization of monoclonal antibodies specific for the murine T cell receptor ζ chain

van Oers, N. S. C., Teh, S. J., Irving, B. A., Tiong, J., Weiss, A. & Teh, H. S., Apr 15 1994, In : Journal of Immunological Methods. 170, 2, p. 261-268 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

Iwashima, M., Irving, B. A., Van Oers, N. S. C., Chan, A. C. & Weiss, A., Jan 1 1994, In : Science. 263, 5150, p. 1136-1139 4 p.

Research output: Contribution to journalArticle

615 Scopus citations

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

van Oers, N. S. C., Killeen, N. & Welss, A., Nov 1994, In : Immunity. 1, 8, p. 675-685 11 p.

Research output: Contribution to journalArticle

215 Scopus citations
1993

CD8 inhibits signal transduction through the T cell receptor in CD4- CD8- thymocytes from T cell receptor transgenic mice reconstituted with a transgenic CD8α molecule

Van Oers, N. S. C., Teh, S. J., Garvin, A. M., Forbush, K. A., Perlmutter, R. M. & Teh, H. S., Jan 1 1993, In : Journal of Immunology. 151, 2, p. 777-790 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein tyrosine kinase activity by TCR ζ

Van Oers, N. S. C., Tao, W., Watts, J. D., Johnson, P., Aebersold, R. & Teh, H. S., Jan 1 1993, In : Molecular and cellular biology. 13, 9, p. 5771-5780 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Mature CD8+ T cells are deleted upon encountering antigen presenting cells in peripheral lymphoid organs

Teh, H. S., Van Oers, N. S. C. & Carlow, D. A., Jan 1 1993, In : EOS Rivista di Immunologia ed Immunofarmacologia. 13, 1, p. 131-132 2 p.

Research output: Contribution to journalArticle

1992

Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions

Carlow, D. A., Van Oers, N. S. C., Teh, S. J. & Teh, H. S., Jan 1 1992, In : Journal of Immunology. 148, 6, p. 1595-1603 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

Differential involvement of protein tyrosine kinases p56(lck) and p59(fyn) in T cell development

Van Oers, N. S. C., Garvin, A. M., Cooke, M. P., Davis, C. B., Littman, D. R., Perlmutter, R. M. & Teh, H. S., 1992, Advances in Experimental Medicine and Biology. Vol. 323. p. 89-100 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Disruption of CD8‐dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck

Van Oers, N. S. C., Garvin, A. M., Davis, C. B., Forbush, K. A., Carlow, D. A., Littman, D. R., Perlmutter, R. M. & Teh, H. S., Mar 1992, In : European Journal of Immunology. 22, 3, p. 735-743 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Peripheral tolerance through clonal deletion of mature CD4-CD8+ T cells

Carlow, D. A., Teh, S. J., Van Oers, N. S. C., Miller, R. G. & Teh, H. S., May 1 1992, In : International Immunology. 4, 5, p. 599-610 12 p.

Research output: Contribution to journalArticle

49 Scopus citations
1990
2 Scopus citations
1989

Isolation and characterization of a distinct immunoregulatory isoform of α-fetoprotein produced by the normal fetus

Van Oers, N. S. C., Cohen, B. L. & Murgita, R. A., 1989, In : Journal of Experimental Medicine. 170, 3, p. 811-825 15 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
1987

Experimental myasthenia gravis induced in mice by passive transfer of human myasthenic immunoglobulin. Evidence for an ameliorating effect by alpha-fetoprotein

Buschman, E., van Oers, N., Katz, M. & Murgita, R. A., Jan 1987, In : Journal of Neuroimmunology. 13, 3, p. 315-330 16 p.

Research output: Contribution to journalArticle

21 Scopus citations
1983

Engineering developments on the ubc-triumf modified pett vi positron emission tomograph

Evans, B., Mackintosh, J., Moore, R. W., Pate, B. D., Rogers, J. G., Ruth, T. J., Sayre, C., Sprenger, H. & Van Oers, N. V., Feb 1983, In : IEEE Transactions on Nuclear Science. 30, 1, p. 707-710 4 p.

Research output: Contribution to journalArticle

39 Scopus citations