Research output per year
Research output per year
- 1 - 50 out of 450 results
Search results
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2022
Serum antibody profiling identifies vaccine-induced correlates of protection against aerosolized ricin toxin in rhesus macaques
Roy, C. J., Ehrbar, D., Van Slyke, G., Doering, J., Didier, P. J., Doyle-Meyers, L., Donini, O., Vitetta, E. S. & Mantis, N. J., Dec 2022, In: npj Vaccines. 7, 1, 164.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2021
Beth Levine M.D. Prize in Autophagy Research
Vitetta, E. S., Cobb, M. H., Hobbs, H. H., Hooper, L., Morrison, S. J., Orth, K., Pfeiffer, J., Rosen, M. K., Takahashi, J. S. & Wang, T., 2021, In: Autophagy. 17, 9, p. 2053 1 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis
Soliman, S. S. M., Baldin, C., Gu, Y., Singh, S., Gebremariam, T., Swidergall, M., Alqarihi, A., Youssef, E. G., Alkhazraji, S., Pikoulas, A., Perske, C., Venkataramani, V., Rich, A., Bruno, V. M., Hotopp, J. D., Mantis, N. J., Edwards, J. E., Filler, S. G., Chamilos, G., Vitetta, E. S., & 1 others, Mar 2021, In: Nature microbiology. 6, 3, p. 313-326 14 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
2020
Endpoint and epitope-specific antibody responses as correlates of vaccine-mediated protection of mice against ricin toxin
Slyke, G. V., Ehrbar, D. J., Doering, J., Yates, J. L., Vitetta, E. S., Donini, O. & Mantis, N. J., Oct 7 2020, In: Vaccine. 38, 43, p. 6721-6729 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin
Roy, C. J., Van Slyke, G., Ehrbar, D., Bornholdt, Z. A., Brennan, M. B., Campbell, L., Chen, M., Kim, D., Mlakar, N., Whaley, K. J., Froude, J. W., Torres-Velez, F. J., Vitetta, E., Didier, P. J., Doyle-Meyers, L., Zeitlin, L. & Mantis, N. J., Dec 1 2020, In: npj Vaccines. 5, 1, 13.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2019
Immunotoxins: A new approach to cancer therapy
Vitetta, E. S., Krolick, K. A., Miyama-Inaban, M., Cushley, W. & Uhr, J. W., Jan 1 2019, Biotechnology and Biological Frontiers. Taylor and Francis, p. 73-85 13 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Rescue of rhesus macaques from the lethality of aerosolized ricin toxin
Roy, C. J., Ehrbar, D. J., Bohorova, N., Bohorov, O., Kim, D., Pauly, M., Whaley, K., Rong, Y., Torres-Velez, F. J., Vitetta, E. S., Didier, P. J., Doyle-Meyers, L., Zeitlin, L. & Mantis, N. J., Jan 10 2019, In: JCI Insight. 4, 1, e124771.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2017
Design and in vivo characterization of immunoconjugates targeting HIV gp160
Pincus, S. H., Song, K., Maresh, G. A., Frank, A., Worthylake, D., Chung, H. K., Polacino, P., Hamer, D. H., Coyne, C. P., Rosenblum, M. G., Marks, J. W., Chen, G., Weiss, D., Ghetie, V., Vitetta, E. S., Robinson, J. E. & Hu, S. L., 2017, In: Journal of virology. 91, 3, e01360-16.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Identification of human anti-HIV gp160 monoclonal antibodies that make effective immunotoxins
Pincus, S. H., Song, K., Maresh, G. A., Hamer, D. H., Dimitrov, D. S., Chen, W., Zhang, M. Y., Ghetie, V. F., Chan-Hui, P. Y., Robinson, J. E. & Vitetta, E. S., 2017, In: Journal of virology. 91, 3, e01955-16.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Tumor dormancy in a murine B cell lymphoma
Uhr, J. W., Tucker, T. & Vitetta, E. S., Jan 1 2017, Cellular Immune Mechanisms and Tumor Dormancy. CRC Press, p. 85-98 14 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2016
Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF
Takeshima, T., Pop, L. M., Laine, A., Iyengar, P., Vitetta, E. S. & Hannan, R., Oct 4 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 40, p. 11300-11305 6 p.Research output: Contribution to journal › Article › peer-review
Open Access122 Scopus citations -
Recent advances in the development of vaccines against ricin
Brey, R. N., Mantis, N. J., Pincus, S. H., Vitetta, E. S., Smith, L. A. & Roy, C. J., May 3 2016, In: Human Vaccines and Immunotherapeutics. 12, 5, p. 1196-1201 6 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access10 Scopus citations -
The role of regulatory b cell-like malignant cells and Treg Cells in the mouse model of BCL1 tumor dormancy
BitMansour, A., Pop, L. M. & Vitetta, E. S., Dec 2016, In: PloS one. 11, 12, e0167618.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2015
Thermostable ricin vaccine protects rhesus macaques against aerosolized ricin: Epitope-specific neutralizing antibodies correlate with protection
Roy, C. J., Brey, R. N., Mantis, N. J., Mapes, K., Pop, I. V., Pop, L. M., Ruback, S., Killeen, S. Z., Doyle-Meyers, L., Vinet-Oliphant, H. S., Didier, P. J. & Vitetta, E. S., Mar 24 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 12, p. 3782-3787 6 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
2014
A reevaluation of CD22 expression in human lung cancer
Pop, L. M., Barman, S., Shao, C., Poe, J. C., Venturi, G. M., Shelton, J. M., Pop, I. V., Gerber, D. E., Girard, L., Liu, X. Y., Behrens, C., Rodriguez-Canales, J., Liu, H., Wistuba, I. I., Richardson, J. A., Minna, J. D., Tedder, T. F. & Vitetta, E. S., Jan 1 2014, In: Cancer research. 74, 1, p. 263-271 9 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2013
Partial Depletion of Regulatory T Cells Does Not Influence the Inflammation Caused by High Dose Hemi-Body Irradiation
Ma, S., Richardson, J. A., Bitmansour, A., Solberg, T. D., Pidikiti, R., Song, K., Stojadinovic, S., Vitetta, E. S. & Meyer, J. J., Feb 11 2013, In: PloS one. 8, 2, e56607.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
T cell-derived b cell differentiation factor(s) effect on the isotype switch of murine b cells
Isakson, P. C., Pure, E., Vitetta, E. S. & Krammer, P. H., Feb 1 2013, In: Journal of Immunology. 190, 3, p. 849-863 15 p.Research output: Contribution to journal › Article › peer-review
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TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens
Sturge, C. R., Benson, A., Raetz, M., Wilhelm, C. L., Mirpuri, J., Vitetta, E. S. & Yarovinsky, F., Jun 25 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 26, p. 10711-10716 6 p.Research output: Contribution to journal › Article › peer-review
101 Scopus citations -
2012
Immunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity
Liu, X. Y., Pop, L. M., Schindler, J. & Vitetta, E. S., Jan 2012, In: mAbs. 4, 1, p. 57-68 12 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Pancreatic ductal adenocarcinoma: A review of immunologic aspects
Wachsmann, M. B., Pop, L. M. & Vitetta, E. S., Apr 2012, In: Journal of Investigative Medicine. 60, 4, p. 643-663 21 p.Research output: Contribution to journal › Review article › peer-review
Open Access50 Scopus citations -
Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine
Vitetta, E. S., Smallshaw, J. E. & Schindler, J., Oct 2012, In: Clinical and Vaccine Immunology. 19, 10, p. 1697-1699 3 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Ricin vaccine development
Smallshaw, J. E. & Vitetta, E. S., 2012, Ricin and Shiga Toxins: Pathogenesis, Immunity, Vaccines and Therapeutics. Mantis, N. & Mantis, N. (eds.). p. 259-272 14 p. (Current Topics in Microbiology and Immunology; vol. 357).Research output: Chapter in Book/Report/Conference proceeding › Chapter
35 Scopus citations -
2011
A comparison of the anti-tumor effects of a chimeric Versus murine anti-CD19 immunotoxins on human B cell lymphoma and pre-B acute lymphoblastic leukemia cell lines
Tsai, L. K., Pop, L. M., Liu, X. & Vitetta, E. S., Apr 2011, In: Toxins. 3, 4, p. 409-419 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
A phase I study of a combination of anti-CD19 and anti-CD22 immunotoxins (Combotox) in adult patients with refractory B-lineage acute lymphoblastic leukaemia
Schindler, J., Gajavelli, S., Ravandi, F., Shen, Y., Parekh, S., Braunchweig, I., Barta, S., Ghetie, V., Vitetta, E. & Verma, A., Aug 2011, In: British Journal of Haematology. 154, 4, p. 471-476 6 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Chimeric, divalent and tetravalent anti-CD19 monoclonal antibodies with potent in vitro and in vivo antitumor activity against human B-cell lymphoma and pre-B acute lymphoblastic leukemia cell lines
Liu, X. Y., Pop, L. M., Tsai, L., Pop, I. V. & Vitetta, E. S., Jul 15 2011, In: International Journal of Cancer. 129, 2, p. 497-506 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Passive and active vaccination strategies to prevent ricin poisoning
Pincus, S. H., Smallshaw, J. E., Song, K., Berry, J. & Vitetta, E. S., Sep 2011, In: Toxins. 3, 9, p. 1163-1184 22 p.Research output: Contribution to journal › Review article › peer-review
32 Scopus citations -
Structure of RiVax: A recombinant ricin vaccine
Legler, P. M., Brey, R. N., Smallshaw, J. E., Vitetta, E. S. & Millard, C. B., Sep 2011, In: Acta Crystallographica Section D: Biological Crystallography. 67, 9, p. 826-830 5 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
The importance of cellular internalization of antibody-targeted carbon nanotubes in the photothermal ablation of breast cancer cells
Marches, R., Mikoryak, C., Wang, R. H., Pantano, P., Draper, R. K. & Vitetta, E. S., Mar 4 2011, In: Nanotechnology. 22, 9, 095101.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
2010
A lyophilized formulation of RiVax, a recombinant ricin subunit vaccine, retains immunogenicity
Smallshaw, J. E. & Vitetta, E. S., Mar 11 2010, In: Vaccine. 28, 12, p. 2428-2435 8 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxication
Marconescu, P. S., Smallshaw, J. E., Pop, L. M., Ruback, S. L. & Vitetta, E. S., Jul 2010, In: Vaccine. 28, 32, p. 5315-5322 8 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2009
A phase 1 study of combotox in pediatric patients with refractory B-lineage acute lymphoblastic leukemia
Herrera, L., Bostrom, B., Gore, L., Sandler, E., Lew, G., Schlegel, P. G., Aquino, V., Ghetie, V., Vitetta, E. S. & Schindler, J., Dec 2009, In: Journal of Pediatric Hematology/Oncology. 31, 12, p. 936-941 6 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
Specific thermal ablation of tumor cells using single-walled carbon nanotubes targeted by covalently-coupled monoclonal antibodies
Marches, R., Chakravarty, P., Musselman, I. H., Bajaj, P., Azad, R. N., Pantano, P., Draper, R. K. & Vitetta, E. S., Dec 15 2009, In: International Journal of Cancer. 125, 12, p. 2970-2977 8 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines
Pop, I., Pop, L., Ghetie, M. A. & Vitetta, E. S., 2009, In: Leukemia and Lymphoma. 50, 7, p. 1155-1162 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2008
Engineering therapeutic monoclonal antibodies
Liu, X. Y., Pop, L. M. & Vitetta, E. S., Apr 2008, In: Immunological Reviews. 222, 1, p. 9-27 19 p.Research output: Contribution to journal › Review article › peer-review
88 Scopus citations -
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein
Pop, I., Pop, L., Vitetta, E. S. & Ghetie, M. A., Apr 2008, In: Oncology reports. 19, 4, p. 889-895 7 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration
Powell, D. J., Attia, P., Ghetie, V., Schindlerv, J., Vitetta, E. S. & Rosenberg, S. A., Feb 2008, In: Journal of Immunotherapy. 31, 2, p. 189-198 10 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
The antitumor activity of an anti-CD54 antibody in SCID mice xenografted with human breast, prostate, non-small cell lung, and pancreatic tumor cell lines
Brooks, K. J., Coleman, E. J. & Vitetta, E. S., Nov 15 2008, In: International Journal of Cancer. 123, 10, p. 2438-2445 8 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes
Chakravarty, P., Marches, R., Zimmerman, N. S., Swafford, A. D. E., Bajaj, P., Musselman, I. H., Pantano, P., Draper, R. K. & Vitetta, E. S., Jun 24 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 25, p. 8697-8702 6 p.Research output: Contribution to journal › Article › peer-review
Open Access350 Scopus citations -
2007
Cancer Dormancy: Lessons from a B Cell Lymphoma and Adenocarcinoma of the Prostate
Rabinovsky, R., Uhr, J. W., Vitetta, E. S. & Yefenof, E., 2007, In: Advances in Cancer Research. 97, p. 189-202 14 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
Letting go
Vitetta, E., Nov 2007, In: Nature biotechnology. 25, 11, p. 1221-1222 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Reconstitution of FOXP3+ regulatory T cells (Tregs) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease
Mielke, S., Rezvani, K., Savani, B. N., Nunes, R., Yong, A. S. M., Schindler, J., Kurlander, R., Ghetie, V., Read, E. J., Solomon, S. R., Vitetta, E. S. & Barrett, A. J., Sep 1 2007, In: Blood. 110, 5, p. 1689-1697 9 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
RiVax, a recombinant ricin subunit vaccine, protects mice against ricin delivered by gavage or aerosol
Smallshaw, J. E., Richardson, J. A. & Vitetta, E. S., Oct 16 2007, In: Vaccine. 25, 42, p. 7459-7469 11 p.Research output: Contribution to journal › Article › peer-review
90 Scopus citations -
2006
A comparison of an anti-CD25 immunotoxin, Ontak and anti-CD25 microbeads for their ability to deplete alloreactive T cells in vitro
Vaclavkova, P., Cao, Y., Wu, L. K., Michalek, J. & Vitetta, E. S., Mar 2006, In: Bone Marrow Transplantation. 37, 6, p. 559-567 9 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation
Amrolia, P. J., Muccioli-Casadei, G., Huls, H., Adams, S., Durett, A., Gee, A., Yvon, E., Weiss, H., Cobbold, M., Gaspar, H. B., Rooney, C., Kuehnle, I., Ghetie, V., Schindler, J., Krance, R., Heslop, H. E., Veys, P., Vitetta, E. & Brenner, M. K., Sep 15 2006, In: Blood. 108, 6, p. 1797-1808 12 p.Research output: Contribution to journal › Article › peer-review
211 Scopus citations -
Anti-CD19 immunotoxin enhances the activity of chemotherapy in severe combined immunodeficient mice with human pre-B acute lymphoblastic leukemia
Herrera, L., Stanciu-Herrera, C., Morgan, C., Ghetie, V. & Vitetta, E. S., Nov 2006, In: Leukemia and Lymphoma. 47, 11, p. 2380-2387 8 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
A pilot clinical trial of a recombinant ricin vaccine in normal humans
Vitetta, E. S., Smallshaw, J. E., Coleman, E., Jafri, H., Foster, C., Munford, R. & Schindler, J., Feb 14 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 7, p. 2268-2273 6 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
Considering therapeutic antibodies
Vitetta, E. S. & Ghetie, V. F., Jul 21 2006, In: Science. 313, 5785, p. 308-309 2 p.Research output: Contribution to journal › Review article › peer-review
30 Scopus citations -
Effect of an anti-cd54 (ICAM-1) monoclonal antibody (UV3) on the growth of human uveal melanoma cells transplanted heterotopically and orthotopically in SCID mice
Wang, S., Coleman, E. J., Pop, L. M., Brooks, K. J., Vitetta, E. S. & Niederkorn, J. Y., Feb 15 2006, In: International Journal of Cancer. 118, 4, p. 932-941 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Erratum: A pilot clinical trial of a recombinant ricin vaccine in normal humans (Proceedings of The National Academy of Sciences of the United States of America (February 14, 2006) 103, 7 (2268-2273) 10.1073/pnas.0510893103)
Vitetta, E. S., Smallshaw, J. E., Coleman, E., Jafri, H., Foster, C., Munford, R. & Schindler, J., Mar 14 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 11, p. 4328 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Generation and characterization of a novel tetravalent anti-CD22 antibody with improved antitumor activity and pharmacokinetics
Liu, X. Y., Pop, L. M., Roopenian, D. C., Ghetie, V., Vitetta, E. S. & Smallshaw, J. E., May 2006, In: International Immunopharmacology. 6, 5, p. 791-799 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations