Int Med - Chairman's Office

Research Output 1947 2019

2019
4 Citations (Scopus)

Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis

BasuRay, S., Wang, Y., Smagris, E., Cohen, J. C. & Hobbs, H. H., May 7 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9521-9526 6 p.

Research output: Contribution to journalArticle

Open Access
Phospholipases
Liver
Triglycerides
Fatty Liver
Liver Diseases
Gluconeogenesis
Pyruvic Acid
Hepatocellular Carcinoma
Oxidoreductases
Pyruvate Carboxylase

A Pilot Study Evaluating a Binge-Eating Screener in Children: Development of the Children’s Brief Binge-Eating Questionnaire in a Pediatric Obesity Clinic

Franklin, E. V., Simpson, V., Berthet-Miron, M., Gupta, O. T. & Barlow, S. E., Sep 1 2019, In : Clinical Pediatrics. 58, 10, p. 1063-1071 9 p.

Research output: Contribution to journalArticle

Binge-Eating Disorder
Bulimia
Pediatric Obesity
Child Development
Reproducibility of Results
1 Citation (Scopus)

Assessing the pentose phosphate pathway using [2, 3- 13 C 2 ]glucose

Lee, M. H., Malloy, C. R., Corbin, I. R., Li, J. & Jin, E. S., Jan 1 2019, In : NMR in biomedicine. e4096.

Research output: Contribution to journalArticle

Pentoses
Pentose Phosphate Pathway
Phosphates
Glucose
Lactic Acid
2 Citations (Scopus)

Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency

Jakkamsetti, V., Marin-Valencia, I., Ma, Q., Good, L. B., Terrill, T., Rajasekaran, K., Pichumani, K., Khemtong, C., Hooshyar, M. A., Sundarrajan, C., Patel, M. S., Bachoo, R., Malloy, C. R. & Pascual, J. M., Jan 1 2019, In : Science Translational Medicine. 11, 480, aan0457.

Research output: Contribution to journalArticle

Pyruvate Dehydrogenase Complex Deficiency Disease
Citric Acid Cycle
Brain
Glutamic Acid
Pyruvic Acid

Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group

Fonseca, A., Xia, C., Lorenzo, A. J., Krailo, M., Olson, T. A., Pashankar, F., Malogolowkin, M. H., Amatruda, J. F., Billmire, D. F., Rodriguez-Galindo, C., Frazier, A. L. & Shaikh, F., Feb 10 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 5, p. 396-402 7 p.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
Tumor Biomarkers
Recurrence
Ionizing Radiation
Pathology

Development and Validation of a Nomogram Prognostic Model for Patients With Advanced Non-Small-Cell Lung Cancer

Wang, T., Lu, R., Lai, S., Schiller, J. H., Zhou, F. L., Ci, B., Wang, S., Gao, X., Yao, B., Gerber, D. E., Johnson, D. H., Xiao, G. & Xie, Y., Apr 1 2019, In : Cancer Informatics. 18

Research output: Contribution to journalArticle

Open Access
Nomograms
Non-Small Cell Lung Carcinoma
ROC Curve
Neoplasm Metastasis
Survival
6 Citations (Scopus)

Development and Validation of a Risk Prediction Model for In-Hospital Mortality among Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - ABCD-10

Noe, M. H., Rosenbach, M., Hubbard, R. A., Mostaghimi, A., Cardones, A. R., Chen, J. K., Cotliar, J., Davis, M. D. P., Dominguez, A. R., Fox, L. P., Hughey, L. C., Kaffenberger, B. H., Kroshinsky, D., Kwong, B. Y., Miller, D. D., Musiek, A., Ortega-Loayza, A. G., Sharon, V. R., Shinkai, K., Summers, E. M. & 6 others, Wanat, K. A., Wetter, D. A., Worswick, S., Margolis, D. J., Gelfand, J. M. & Micheletti, R. G., Apr 1 2019, In : JAMA Dermatology. 155, 4, p. 448-454 7 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
Bicarbonates
Hospital Mortality
Dialysis
Neoplasms

Diagnosis: Gastric intestinal metaplasia: What to do next?

Graham, D. Y., Rugge, M. & Genta, R. M., Jan 1 2019, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalReview article

Metaplasia
Stomach
Stomach Neoplasms
Carcinogenesis
Biopsy
1 Citation (Scopus)

Disorders of Iron Metabolism: New Diagnostic and Treatment Approaches to Iron Deficiency

Powers, J. M. & Buchanan, G. R., Jun 1 2019, In : Hematology/Oncology Clinics of North America. 33, 3, p. 393-408 16 p.

Research output: Contribution to journalReview article

Iron Metabolism Disorders
Iron
Iron-Deficiency Anemias
Anemia
Therapeutics

Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma

National Institute of Allergy and Infectious Diseases–sponsored Inner-City Asthma Consortium, Nov 2019, In : Journal of Allergy and Clinical Immunology. 144, 5, p. 1187-1197 11 p.

Research output: Contribution to journalArticle

Microbiota
Nose
Asthma
Moraxella
Pediatrics

Editorial: Renal transplantation: a brief history and outlook for the future

Baum, M. G., Apr 1 2019, In : Current opinion in pediatrics. 31, 2, p. 210-212 3 p.

Research output: Contribution to journalArticle

Kidney Transplantation
History
13 Citations (Scopus)

Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion among Children with Peanut Allergy: The PEPITES Randomized Clinical Trial

Fleischer, D. M., Greenhawt, M., Sussman, G., Bégin, P., Nowak-Wegrzyn, A., Petroni, D., Beyer, K., Brown-Whitehorn, T., Hebert, J., Hourihane, J. O. B., Campbell, D. E., Leonard, S., Chinthrajah, R. S., Pongracic, J. A., Jones, S. M., Lange, L., Chong, H., Green, T. D., Wood, R., Cheema, A. & 13 others, Prescott, S. L., Smith, P., Yang, W., Chan, E. S., Byrne, A., Assa'Ad, A., Bird, J. A., Kim, E. H., Schneider, L., Davis, C. M., Lanser, B. J., Lambert, R. & Shreffler, W., Mar 12 2019, In : JAMA - Journal of the American Medical Association. 321, 10, p. 946-955 10 p.

Research output: Contribution to journalArticle

Peanut Hypersensitivity
Immunotherapy
Randomized Controlled Trials
Eating
Placebos

Effect of sex on glomerular filtration rate in programmed rats by prenatal dexamethasone

Jain, J., Legan, S. K., Alhamoud, I., Gattineni, J. & Baum, M. G., Jul 1 2019, In : Physiological Reports. 7, 12, e14154.

Research output: Contribution to journalArticle

Open Access
Glomerular Filtration Rate
Dexamethasone
Blood Pressure
Hypertension
Pregnancy
1 Citation (Scopus)
health science
health service
public health
resident
examination

Factor VIII prophylaxis effects outweigh other hemostasis contributors in predicting severe haemophilia A joint outcomes

for the Joint Outcome Study Group Investigators, Jan 1 2019, In : Haemophilia.

Research output: Contribution to journalArticle

Factor VIII
Hemophilia A
Hemostasis
Joints
Outcome Assessment (Health Care)

Genetics of testicular germ cell tumors

Singla, N., Lafin, J. T., Ghandour, R. A., Kaffenberger, S., Amatruda, J. F. & Bagrodia, A., Jul 1 2019, In : Current opinion in urology. 29, 4, p. 344-349 6 p.

Research output: Contribution to journalArticle

Testicular Germ Cell Tumor
Seminoma
Mutation
Penetrance
Loss of Heterozygosity

Homozygous rare Parn missense mutation in familial pulmonary fibrosis

Zhang, D., Zhou, Z., Abu-Hijleh, M. A., Batra, K., Xing, C. & Garcia, C. K., Mar 15 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 6, p. 797-799 3 p.

Research output: Contribution to journalLetter

Pulmonary Fibrosis
Missense Mutation

Identification of testicular cancer driver genes by a cross-species comparative oncology approach

Sanchez, A., Xu, L., Pierce, J. L., Lafin, J. T., Abe, D., Bagrodia, A., Frazier, A. L. & Amatruda, J. F., Jan 1 2019, In : Andrology.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
Neoplasm Genes
Testicular Neoplasms
Zebrafish
Germ Cells

Identifying barriers to implementation of emergency epinephrine bills: The Texas experience

Yeh, C. Y., Wheeler, A., Bethea, L., Bird, J. A., Fulbright, J., Freeman, T., Gonzalez-Reyes, E., Jeffrey, D., Schwind, K., Stafford, W., Varshney, P., Beard, C. & Davis, C. M., Jan 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Epinephrine
Emergencies
Insulin
Subcutaneous Infusions
Injections
Area Under Curve
Analysis of Variance
1 Citation (Scopus)

New insights into germ cell tumor genomics

Lafin, J. T., Bagrodia, A., Woldu, S. & Amatruda, J. F., Jan 1 2019, In : Andrology.

Research output: Contribution to journalReview article

Germ Cell and Embryonal Neoplasms
Genomics
Platinum
Immunotherapy
Neoplasms
6 Citations (Scopus)

PNPLA3, CGI-58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice

Wang, Y., Kory, N., BasuRay, S., Cohen, J. C. & Hobbs, H. H., Jan 1 2019, In : Hepatology.

Research output: Contribution to journalArticle

Open Access
Phospholipases
Triglycerides
Hydrolysis
Lipase
Liver
2 Citations (Scopus)

Prevention of food allergy: Beyond peanut

Bird, J. A., Parrish, C. P., Patel, K., Shih, J. A. & Vickery, B. P., Feb 1 2019, In : Journal of Allergy and Clinical Immunology. 143, 2, p. 545-547 3 p.

Research output: Contribution to journalEditorial

Egg Hypersensitivity
Food Hypersensitivity
Arachis

Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high-grade gliomas

Todorova, P. K., Fletcher-Sananikone, E., Mukherjee, B., Kollipara, R., Vemireddy, V., Xie, X-J., Guida, P. M., Story, M. D., Hatanpaa, K., Habib, A. A., Kittler, R., Bachoo, R., Hromas, R., Floyd, J. R. & Burma, S., Jan 1 2019, In : Cancer Research. 79, 14, p. 3749-3761 13 p.

Research output: Contribution to journalArticle

Glioma
DNA Damage
Radiation
Linear Energy Transfer
Neoplasms

Reducing Hospitalizations: Institution of Outpatient Infusional EPOCH-Based Chemotherapy at a Safety Net Hospital

Keshvani, N., Hon, M., Gupta, A., Brown, T. J., Roy, L., Marley, E., Lindsey, S., Johnson, D. H., Sadeghi, N. & Li, H-C., Aug 1 2019, In : Journal of oncology practice. 15, 8, p. e644-e651

Research output: Contribution to journalArticle

Safety-net Providers
Hospitalization
Outpatients
Drug Therapy
Inpatients
Macrophage Activation Syndrome
Adult-Onset Still's Disease
Hemophagocytic Lymphohistiocytosis
Tacrolimus
Biopsy

Secondary prevention of gastric cancer: Merging the endoscopic atrophic border with OLGA staging

Rugge, M., Sacchi, D., Graham, D. Y. & Genta, R. M., Jan 1 2019, In : Gut.

Research output: Contribution to journalLetter

Stomach Diseases
Helicobacter Infections
Secondary Prevention
Stomach Neoplasms

Second-line treatments in children with immune thrombocytopenia: Effect on platelet count and patient-centered outcomes

Grace, R. F., Shimano, K. A., Bhat, R., Neunert, C., Bussel, J. B., Klaassen, R. J., Lambert, M. P., Rothman, J. A., Breakey, V. R., Hege, K., Bennett, C. M., Rose, M. J., Haley, K. M., Buchanan, G. R., Geddis, A., Lorenzana, A., Jeng, M., Pastore, Y. D., Crary, S. E., Neier, M. & 4 others, Neufeld, E. J., Neu, N., Forbes, P. W. & Despotovic, J. M., Jul 1 2019, In : American Journal of Hematology. 94, 7, p. 741-750 10 p.

Research output: Contribution to journalArticle

Open Access
Idiopathic Thrombocytopenic Purpura
Platelet Count
Hemorrhage
Quality of Life
Therapeutics

Seurat's Dots: A Shot Heard ’Round the Art World—Fired by an Artist, Inspired by a Scientist

Goldstein, J. L., Sep 19 2019, In : Cell. 179, 1, p. 46-50 5 p.

Research output: Contribution to journalComment/debate

Open Access
Art
Color
Imagination
6 Citations (Scopus)

Telomere length and genetic variant associations with interstitial lung disease progression and survival

Newton M.D., C. A., Oldham, J. M., Ley, B., Anand, V., Adegunsoye, A., Liu, G., Batra, K., Torrealba, J. R., Kozlitina, J., Glazer, C. S., Strek, M. E., Wolters, P. J., Noth, I. & Garcia, C. K., Apr 1 2019, In : The European respiratory journal. 53, 4

Research output: Contribution to journalArticle

Open Access
Interstitial Lung Diseases
Telomere
Disease Progression
Leukocytes
Idiopathic Pulmonary Fibrosis
5 Citations (Scopus)

Telomere Length and Use of Immunosuppressive Medications in Idiopathic Pulmonary Fibrosis

Newton, C. A., Zhang, D., Oldham, J. M., Kozlitina, J., Ma, S. F., Martinez, F. J., Raghu, G., Noth, I. & Garcia, C. K., Aug 1 2019, In : American journal of respiratory and critical care medicine. 200, 3, p. 336-347 12 p.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Telomere
Immunosuppressive Agents
Leukocytes
Immunosuppression

The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions

Fox, A., Bird, J. A., Fiocchi, A., Knol, J., Meyer, R., Salminen, S., Sitang, G., Szajewska, H. & Papadopoulos, N., Jan 1 2019, In : World Allergy Organization Journal. 12, 5, 100034.

Research output: Contribution to journalReview article

Open Access
Synbiotics
Milk Hypersensitivity
Probiotics
Food Hypersensitivity
Hypersensitivity
5 Citations (Scopus)

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Altman, M. C., Gill, M. A., Whalen, E., Babineau, D. C., Shao, B., Liu, A. H., Jepson, B., Gruchalla, R. S., O’Connor, G. T., Pongracic, J. A., Kercsmar, C. M., Khurana Hershey, G. K., Zoratti, E. M., Johnson, C. C., Teach, S. J., Kattan, M., Bacharier, L. B., Beigelman, A., Sigelman, S. M., Presnell, S. & 6 others, Gern, J. E., Gergen, P. J., Wheatley, L. M., Togias, A., Busse, W. W. & Jackson, D. J., May 1 2019, In : Nature Immunology. 20, 5, p. 637-651 15 p.

Research output: Contribution to journalArticle

Transcriptome
Asthma
Viruses
Mucus
Epidermal Growth Factor Receptor

Type I interferon suppresses memory Th2 cell cytokine secretion from allergic subjects

Chen, F., Rowe, R. K., Gill, M. A. & Farrar, J. D., Jan 1 2019, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalLetter

Interferon Type I
Th2 Cells
Cytokines

Validation of the 12-gene predictive signature for adjuvant chemotherapy response in lung cancer

Xie, Y., Lu, W., Wang, S., Tang, X., Tang, H., Zhou, Y., Moran, C., Behrens, C., Roth, J. A., Zhou, Q., Johnson, D. H., Swisher, S. G., Heymach, J. V., Papadimitrakopoulou, V. A., Xiao, G., Minna, J. D. & Wistuba, I. I., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Lung Neoplasms
Genes
Non-Small Cell Lung Carcinoma
Paraffin

α-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium

O’Neill, A. F., Xia, C., Krailo, M. D., Shaikh, F., Pashankar, F. D., Billmire, D. F., Olson, T. A., Amatruda, J. F., Villaluna, D., Huang, L., Malogolowkin, M., Rodriguez-Galindo, C. & Frazier, A. L., Jan 1 2019, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Fetal Proteins
Germ Cell and Embryonal Neoplasms
Germ Cells
Recurrence
Drug Therapy
2018

2018 association of American physicians George M. Kober lecture science, serendipity, and the single degree

Hobbs, H. H., Oct 1 2018, In : Journal of Clinical Investigation. 128, 10, p. 4218-4223 6 p.

Research output: Contribution to journalReview article

Physicians

Acute syndrome of pan-epidermolysis and thrombotic storm arising in a patient with systemic lupus erythematosus

Burger, E., Gou, D., Vandergriff, T., Dominguez, A. & Mauskar, M., Oct 1 2018, In : JAAD Case Reports. 4, 9, p. 877-879 3 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
2 Citations (Scopus)

Additional oral food challenge considerations

Bird, J. A., Fleischer, D. M., Groetch, M., Nowak-Węgrzyn, A., Sicherer, S. & Young, M. C., Jun 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, 1 p.

Research output: Contribution to journalLetter

Food
3 Citations (Scopus)

Adrenergic signaling at the interface of allergic asthma and viral infections

Agaç, D., Gill, M. A. & Farrar, J. D., Apr 11 2018, In : Frontiers in Immunology. 9, APR, 736.

Research output: Contribution to journalArticle

Virus Diseases
Adrenergic Agents
Asthma
Rhinovirus
Norepinephrine

Allergic proctocolitis is a risk factor for functional gastrointestinal disorders in children

Chow, T. & Bird, J. A., Dec 1 2018, In : Pediatrics. 142, p. S245-S246

Research output: Contribution to journalComment/debate

Open Access
Proctocolitis
Gastrointestinal Diseases
3 Citations (Scopus)

Applying the 'COST' (Culture, Oversight, Systems Change, and Training) Framework to De-Adopt the Neutropenic Diet

Gupta, A., Brown, T. J., Singh, S., Sen, A., Agrawal, D., Li, H. C., Moriates, C., Johnson, D. H. & Sadeghi, N., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Diet
68 Citations (Scopus)

A protein-truncating HSD17B13 variant and protection from chronic liver disease

Abul-Husn, N. S., Cheng, X., Li, A. H., Xin, Y., Schurmann, C., Stevis, P., Liu, Y., Kozlitina, J., Stender, S., Wood, G. C., Stepanchick, A. N., Still, M. D., McCarthy, S., O'Dushlaine, C., Packer, J. S., Balasubramanian, S., Gosalia, N., Esopi, D., Kim, S. Y., Mukherjee, S. & 28 others, Lopez, A. E., Fuller, E. D., Penn, J., Chu, X., Luo, J. Z., Mirshahi, U. L., Carey, D. J., Still, C. D., Feldman, M. D., Small, A., Damrauer, S. M., Rader, D. J., Zambrowicz, B., Olson, W., Murphy, A. J., Borecki, I. B., Shuldiner, A. R., Reid, J. G., Overton, J. D., Yancopoulos, G. D., Hobbs, H. H., Cohen, J. C., Gottesman, O., Teslovich, T. M., Baras, A., Mirshahi, T., Gromada, J. & Dewey, F. E., Mar 22 2018, In : New England Journal of Medicine. 378, 12, p. 1096-1106 11 p.

Research output: Contribution to journalArticle

Liver Diseases
Chronic Disease
Confidence Intervals
Homozygote
Heterozygote
1 Citation (Scopus)

Associations of Microscopic Colitis With Other Lymphocytic Disorders of the Gastrointestinal Tract

Sonnenberg, A., Turner, K. O. & Genta, R. M., Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Microscopic Colitis
Gastrointestinal Tract
Upper Gastrointestinal Tract
Comorbidity
Lower Gastrointestinal Tract
1 Citation (Scopus)

Baked egg oral immunotherapy desensitizes baked egg allergic children to lightly cooked egg

Bird, J. A., Clark, A., Dougherty, I., Brown, L. S., Arneson, A., Crain, M. & Parrish, C., Jan 1 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Immunotherapy
Ovum
3 Citations (Scopus)

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver

Tian, J., Wu, J., Chen, X., Guo, T., Chen, Z. J., Goldstein, J. L. & Brown, M. S., Jun 27 2018, In : eLife. 7, e36826.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Protein 1
Liver
Rodentia
Transcription Factors
Insulin

Burden of poor health conditions and quality of life in 656 children with primary immunodeficiency

Nicolaides, R. E. & Bird, J. A., Dec 1 2018, In : Pediatrics. 142, p. S272-S273

Research output: Contribution to journalComment/debate

Open Access
Quality of Life
Health