Research output per year
Research output per year
- 1 - 50 out of 1,251 results
Search results
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2024
Adipose Tissue Analysis Toolkit (ATAT) for automated analysis of adipocyte size and extracellular matrix in white adipose tissue
Robino, J. J., Plekhanov, A. P., Zhu, Q., Jensen, M. D., Scherer, P. E., Roberts, C. T. & Varlamov, O., Apr 2024, In: Obesity. 32, 4, p. 723-732 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
CRISPR-Cas9 base editing of pathogenic CaMKIIδ improves cardiac function in a humanized mouse model
Lebek, S., Caravia, X. M., Straub, L. G., Alzhanov, D., Tan, W., Li, H., McAnally, J. R., Chen, K., Xu, L., Scherer, P. E., Liu, N., Bassel-Duby, R. & Olson, E. N., Jan 20 2024, In: Journal of Clinical Investigation. 134, 1, e175164.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Evaluation of the efficacy of a combination of dapagliflozin and lobeglitazone on glucose concentrations and body fat in patients with type 2 diabetes: Location-F study
Choe, H. J., Oh, H. R., Bu, D., An, N., Scherer, P. E., An, Z. & Lim, S., Mar 2024, In: Diabetes, Obesity and Metabolism. 26, 3, p. 1114-1119 6 p.Research output: Contribution to journal › Letter › peer-review
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GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Furber, E. C., Hyatt, K., Collins, K., Yu, X., Droz, B. A., Holland, A., Friedrich, J. L., Wojnicki, S., Konkol, D. L., O’Farrell, L. S., Baker, H. E., Coskun, T., Scherer, P. E., Kusminski, C. M., Christe, M. E., Sloop, K. W. & Samms, R. J., Feb 2024, In: Diabetes. 73, 2, p. 292-305 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Leptin Reduction as a Required Component for Weight Loss
Zhao, S., Li, N., Xiong, W., Li, G., He, S., Zhang, Z., Zhu, Q., Jiang, N., Ikejiofor, C., Zhu, Y., Wang, M. Y., Han, X., Zhang, N., Solis-Herrera, C., Kusminski, C., An, Z., Elmquist, J. K. & Scherer, P. E., Feb 2024, In: Diabetes. 73, 2, p. 197-210 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Adipose tissue fibrosis: the unwanted houseguest invited by obesity
Gliniak, C. M., Pedersen, L. & Scherer, P. E., 2023, In: Journal of Endocrinology. 259, 3, e230180.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Control of adipose tissue cellularity by the terminal complement cascade
Kruglikov, I. L. & Scherer, P. E., Dec 2023, In: Nature Reviews Endocrinology. 19, 12, p. 679-680 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
Onodera, T., Wang, M. Y., Rutkowski, J. M., Deja, S., Chen, S., Balzer, M. S., Kim, D. S., Sun, X., An, Y. A., Field, B. C., Lee, C., Matsuo, E. I., Mizerska, M., Sanjana, I., Fujiwara, N., Kusminski, C. M., Gordillo, R., Gautron, L., Marciano, D. K., Hu, M. C., & 4 others, Dec 2023, In: Nature communications. 14, 1, 6531.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model
An, Y. A., Xiong, W., Chen, S., Bu, D., Rutkowski, J. M., Berger, J. P., Kusminski, C. M., Zhang, N., An, Z. & Scherer, P. E., Mar 2023, In: Molecular Metabolism. 69, 101680.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Extracellular Matrix (ECM) and Fibrosis in Adipose Tissue: Overview and Perspectives
Sun, K., Li, X. & Scherer, P. E., Jan 2023, In: Comprehensive Physiology. 13, 1, p. 4387-4407 21 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
GPR84-mediated signal transduction affects metabolic function by promoting brown adipocyte activity
Sun, X. N., An, Y. A., Paschoal, V. A., de Souza, C. O., Wang, M. Y., Vishvanath, L., Bueno, L. M. A., Cobb, A. S., Nieto Carrion, J. A., Ibe, M. E., Li, C., Kidd, H. A., Chen, S., Li, W., Gupta, R. K. & Oh, D. Y., Dec 1 2023, In: Journal of Clinical Investigation. 133, 24, e168992.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Hepatic sialic acid synthesis modulates glucose homeostasis in both liver and skeletal muscle
Peng, J., Yu, L., Huang, L., Paschoal, V. A., Chu, H., de Souza, C. O., Varre, J. V., Oh, D. Y., Kohler, J. J., Xiao, X., Xu, L., Holland, W. L., Shaul, P. W. & Mineo, C., Dec 2023, In: Molecular Metabolism. 78, 101812.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
HSP47 levels determine the degree of body adiposity
Shin, J., Toyoda, S., Okuno, Y., Hayashi, R., Nishitani, S., Onodera, T., Sakamoto, H., Ito, S., Kobayashi, S., Nagao, H., Kita, S., Otsuki, M., Fukuhara, A., Nagata, K. & Shimomura, I., Dec 2023, In: Nature communications. 14, 1, 7319.Research output: Contribution to journal › Article › peer-review
Open Access -
Hyperleptinemia contributes to antipsychotic drug–associated obesity and metabolic disorders
Zhao, S., Lin, Q., Xiong, W., Li, L., Straub, L., Zhang, D., Zapata, R., Zhu, Q., Sun, X. N., Zhang, Z., Funcke, J. B., Li, C., Chen, S., Zhu, Y., Jiang, N., Li, G., Xu, Z., Wyler, S. C., Wang, M. Y., Bai, J., & 8 others, Nov 15 2023, In: Science translational medicine. 15, 723, eade8460.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Pathophysiology of cellulite: Possible involvement of selective endotoxemia
Kruglikov, I. L. & Scherer, P. E., Jan 2023, In: Obesity Reviews. 24, 1, e13517.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease
Wang, Z., Zhu, S., Jia, Y., Wang, Y., Kubota, N., Fujiwara, N., Gordillo, R., Lewis, C., Zhu, M., Sharma, T., Li, L., Zeng, Q., Lin, Y. H., Hsieh, M. H., Gopal, P., Wang, T., Hoare, M., Campbell, P., Hoshida, Y. & Zhu, H., Apr 27 2023, In: Cell. 186, 9, p. 1968-1984.e20Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells
Onodera, T., Kim, D. S., Ye, R., Wang, M. Y., Chen, S., Field, B. C., Straub, L., Sun, X. N., Li, C., Lee, C., Paredes, M., Crewe, C., Zhao, S., Kusminski, C. M., Gordillo, R. & Scherer, P. E., Dec 2023, In: Molecular Metabolism. 78, 101821.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
Fu, T., Sun, W., Xue, J., Zhou, Z., Wang, W., Guo, Q., Chen, X., Zhou, D., Xu, Z., Liu, L., Xiao, L., Mao, Y., Yang, L., Yin, Y., Zhang, X. N., Wan, Q., Lu, B., Chen, Y., Zhu, M. S., Scherer, P. E., & 4 others, Jun 2023, In: Nature cell biology. 25, 6, p. 848-864 17 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue
Agarwal, A. K., Tunison, K., Vale, G., McDonald, J. G., Li, X., Scherer, P. E., Horton, J. D. & Garg, A., Oct 20 2023, In: iScience. 26, 10, 107806.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation
Song, R., Fond, A., Li, X., Tang, M., Zhan, X., Gordillo, R., Moresco, E. M. Y., Beutler, B. & Turer, E. E., Sep 2023, In: DMM Disease Models and Mechanisms. 16, 9, dmm050043.Research output: Contribution to journal › Article › peer-review
Open Access -
The interplay between leptin, glucocorticoids, and GLP1 regulates food intake and feeding behaviour
Perez-Leighton, C., Kerr, B., Scherer, P. E., Baudrand, R. & Cortés, V., 2023, (Accepted/In press) In: Biological Reviews.Research output: Contribution to journal › Article › peer-review
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Update on Adipose Tissue and Cancer
Brown, K. A. & Scherer, P. E., Dec 1 2023, In: Endocrine reviews. 44, 6, p. 961-974 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
2022
Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
Zhu, Y., Li, N., Huang, M., Chen, X., An, Y. A., Li, J., Zhao, S., Funcke, J. B., Cao, J., He, Z., Zhu, Q., Zhang, Z., Wang, Z. V., Xu, L., Williams, K. W., Li, C., Grove, K. & Scherer, P. E., Jul 2022, In: Acta Pharmaceutica Sinica B. 12, 7, p. 3063-3072 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Adipocyte mesenchymal transition contributes to mammary tumor progression
Zhu, Q., Zhu, Y., Hepler, C., Zhang, Q., Park, J., Gliniak, C., Henry, G. H., Crewe, C., Bu, D., Zhang, Z., Zhao, S., Morley, T., Li, N., Kim, D. S., Strand, D., Deng, Y., Robino, J. J., Varlamov, O., Gordillo, R., Kolonin, M. G., & 3 others, Sep 13 2022, In: Cell Reports. 40, 11, 111362.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Adiponectin and cardiometabolic trait and mortality: where do we go?
Jang, A. Y., Scherer, P. E., Kim, J. Y., Lim, S. & Koh, K. K., May 1 2022, In: Cardiovascular Research. 118, 9, p. 2074-2084 11 p.Research output: Contribution to journal › Review article › peer-review
10 Scopus citations -
Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations
Joffin, N., Gliniak, C. M., Funcke, J. B., Paschoal, V. A., Crewe, C., Chen, S., Gordillo, R., Kusminski, C. M., Oh, D. Y., Geldenhuys, W. J. & Scherer, P. E., Nov 2022, In: Nature Metabolism. 4, 11, p. 1474-1494 21 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells
Perez-Frances, M., Abate, M. V., Baronnier, D., Scherer, P. E., Fujitani, Y., Thorel, F. & Herrera, P. L., Feb 15 2022, In: Cell Reports. 38, 7, 110377.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
A new signal that shrinks fat
Gliniak, C. M. & Scherer, P. E., Mar 2022, In: Nature Metabolism. 4, 3, p. 305-307 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations -
Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
Celen, C., Chuang, J. C., Shen, S., Li, L., Maggiore, G., Jia, Y., Luo, X., Moore, A., Wang, Y., Otto, J. E., Collings, C. K., Wang, Z., Sun, X., Nassour, I., Park, J., Ghaben, A., Wang, T., Wang, S. C., Scherer, P. E., Kadoch, C., & 1 others, Nov 1 2022, In: Cell Reports. 41, 5, 111581.Research output: Contribution to journal › Article › peer-review
Open Access -
ATF4 Protects the Heart From Failure by Antagonizing Oxidative Stress
Wang, X., Zhang, G., Dasgupta, S., Niewold, E. L., Li, C., Li, Q., Luo, X., Tan, L., Ferdous, A., Lorenzi, P. L., Rothermel, B. A., Gillette, T. G., Adams, C. M., Scherer, P. E., Hill, J. A. & Wang, Z. V., Jun 24 2022, In: Circulation research. 131, 1, p. 91-105 15 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Cellular and molecular brakes on adipogenesis
Cannavino, J. & Gupta, R. K., Jan 2022, In: Nature Metabolism. 4, 1, p. 13-14 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Ceramides are early responders in metabolic syndrome development in rhesus monkeys
Smith, A. B., Schill, J. P., Gordillo, R., Gustafson, G. E., Rhoads, T. W., Burhans, M. S., Broman, A. T., Colman, R. J., Scherer, P. E. & Anderson, R. M., Dec 2022, In: Scientific reports. 12, 1, 9960.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Comparison of BMIPP-SPECT/CT to18 FDG-PET/CT for Imaging Brown or Browning Fat in a Preclinical Model
Frankl, J. A., An, Y., Sherwood, A., Hao, G., Huang, F. Y., Thapa, P., Clegg, D. J., Sun, X., Scherer, P. E. & Öz, O. K., May 1 2022, In: International journal of molecular sciences. 23, 9, 4880.Research output: Contribution to journal › Article › peer-review
Open Access -
Crosstalk between adipose tissue and the heart: An update
Li, C., Sun, X. N., Zhao, S. & Scherer, P. E., Sep 1 2022, In: Journal of Translational Internal Medicine. 10, 3, p. 219-226 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
Deficient Caveolin-1 Synthesis in Adipocytes Stimulates Systemic Insulin-Independent Glucose Uptake via Extracellular Vesicles
Crewe, C., Chen, S., Bu, D., Gliniak, C. M., Asterholm, I. W., Yu, X. X., Joffin, N., de Souza, C. O., Funcke, J. B., Oh, D. Y., Varlamov, O., Robino, J. J., Gordillo, R. & Scherer, P. E., Dec 2022, In: Diabetes. 71, 12, p. 2496-2512 17 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers
Kim, D. S., Camacho, C. V., Setlem, R., Kim, K., Malladi, S., Hou, T. Y., Nandu, T., Gadad, S. S. & Kraus, W. L., Nov 2022, In: Molecular Cancer Research. 20, 11, p. 1623-1635 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model
de Souza, C. O., Paschoal, V. A., Sun, X., Vishvanath, L., Zhang, Q., Shao, M., Onodera, T., Chen, S., Joffin, N., Bueno, L. M. A., Gupta, R. K. & Oh, D. Y., Nov 1 2022, In: Journal of Clinical Investigation. 132, 21, e160097.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Insulin sensitive human adipocytes for in vitro studies
Straub, L. G. & Scherer, P. E., Oct 2022, In: Nature Reviews Endocrinology. 18, 10, p. 591-592 2 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Intercellular and interorgan crosstalk through adipocyte extracellular vesicles
Crewe, C. & Scherer, P. E., Feb 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, 1, p. 61-69 9 p.Research output: Contribution to journal › Review article › peer-review
28 Scopus citations -
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis
Patrick, M. K., Gu, Z., Zhang, G., Wynn, R. M., Kaphle, P., Cao, H., Vu, H., Cai, F., Gao, X., Zhang, Y., Chen, M., Ni, M., Chuang, D. T., DeBerardinis, R. J. & Xu, J., Dec 2022, In: Nature Metabolism. 4, 12, p. 1775-1791 17 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Mitochondrial regulation and white adipose tissue homeostasis
Zhu, Q., An, Y. A. & Scherer, P. E., Apr 2022, In: Trends in Cell Biology. 32, 4, p. 351-364 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations -
Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
Shan, B., Barker, C. S., Shao, M., Zhang, Q., Gupta, R. K. & Wu, Y., May 3 2022, In: Cell Metabolism. 34, 5, p. 783-799.e7Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders
Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Apr 1 2022, In: International journal of molecular sciences. 23, 7, 3828.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations -
Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification
Zi, Z., Zhang, Z., Feng, Q., Kim, C., Wang, X. D., Scherer, P. E., Gao, J., Levine, B. & Yu, Y., Dec 2022, In: Nature communications. 13, 1, 1760.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Response to Kunos et al. and Lotersztajn and Mallat
Wang, S., Zhu, Q., Liang, G., Franks, T., Boucher, M., Bence, K. K., Lu, M., Castorena, C. M., Zhao, S., Elmquist, J. K., Scherer, P. E. & Horton, J. D., Jan 4 2022, In: Journal of Clinical Investigation. 132, 1, e156247.Research output: Contribution to journal › Letter › peer-review
Open Access2 Scopus citations -
Skin aging: Dermal adipocytes metabolically reprogram dermal fibroblasts
Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Jan 2022, In: BioEssays. 44, 1, 2100207.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease
Colca, J. R. & Scherer, P. E., Jan 2022, In: Molecular Metabolism. 55, 101409.Research output: Contribution to journal › Review article › peer-review
Open Access13 Scopus citations -
Why does obesity cause diabetes?
Klein, S., Gastaldelli, A., Yki-Järvinen, H. & Scherer, P. E., Jan 4 2022, In: Cell Metabolism. 34, 1, p. 11-20 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access179 Scopus citations -
2021
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity
Zhang, Z., Funcke, J. B., Zi, Z., Zhao, S., Straub, L. G., Zhu, Y., Zhu, Q., Crewe, C., An, Y. A., Chen, S., Li, N., Wang, M. Y., Ghaben, A. L., Lee, C., Gautron, L., Engelking, L. J., Raj, P., Deng, Y., Gordillo, R., Kusminski, C. M., & 1 others, Aug 3 2021, In: Cell Metabolism. 33, 8, p. 1624-1639.e9Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Adiponectin, Leptin and Cardiovascular Disorders
Zhao, S., Kusminski, C. M. & Scherer, P. E., Jan 8 2021, In: Circulation research. 128, 1, p. 136-149 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access150 Scopus citations