Int Med - Touchstone Diab Ctr

Research Output

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Review article
2020

Caveolin as a universal target in dermatology

Kruglikov, I. L. & Scherer, P. E., Jan 1 2020, In : International journal of molecular sciences. 21, 1, 80.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2019

Beyond adiponectin and leptin: Adipose tissue-derived mediators of inter-organ communication

Funcke, J. B. & Scherer, P. E., 2019, In : Journal of lipid research. 60, 10, p. 1648-1697 50 p.

Research output: Contribution to journalReview article

19 Scopus citations

Caveolin-1 as a pathophysiological factor and target in psoriasis

Kruglikov, I. L. & Scherer, P. E., Dec 1 2019, In : npj Aging and Mechanisms of Disease. 5, 1, 4.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Caveolin-1 in skin aging – From innocent bystander to major contributor

Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Nov 2019, In : Ageing Research Reviews. 55, 100959.

Research output: Contribution to journalReview article

5 Scopus citations

Contribution of adipogenesis to healthy adipose tissue expansion in obesity

Vishvanath, L. & Gupta, R. K., Oct 1 2019, In : Journal of Clinical Investigation. 129, 10, p. 4022-4031 10 p.

Research output: Contribution to journalReview article

15 Scopus citations

Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood

Gliniak, C. M. & Scherer, P. E., Jun 3 2019, In : Journal of Clinical Investigation. 129, 6, p. 2198-2200 3 p.

Research output: Contribution to journalReview article

Imaging metabolically active fat: A literature review and mechanistic insights

Frankl, J., Sherwood, A., Clegg, D. J., Scherer, P. E. & Öz, O. K., Nov 2019, In : International journal of molecular sciences. 20, 21, 5509.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution

Wang, Q. A. & Scherer, P. E., Sep 1 2019, In : Journal of mammary gland biology and neoplasia. 24, 3, p. 207-212 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

The Role of Immature and Mature Adipocytes in Hair Cycling

Kruglikov, I. L., Zhang, Z. & Scherer, P. E., Feb 2019, In : Trends in Endocrinology and Metabolism. 30, 2, p. 93-105 13 p.

Research output: Contribution to journalReview article

10 Scopus citations

Unfolded protein response as a therapeutic target in cardiovascular disease

Zhang, G., Wang, X., Gillette, T. G., Deng, Y. & Wang, Z. V., 2019, In : Current topics in medicinal chemistry. 19, 21, p. 1902-1917 16 p.

Research output: Contribution to journalReview article

5 Scopus citations
2018

Immunologic and endocrine functions of adipose tissue: implications for kidney disease

Zhu, Q. & Scherer, P. E., Feb 1 2018, In : Nature Reviews Nephrology. 14, 2, p. 105-120 16 p.

Research output: Contribution to journalReview article

30 Scopus citations
2017

Adipose Tissue: A Safe Haven for Parasites?

Tanowitz, H. B., Scherer, P. E., Mota, M. M. & Figueiredo, L. M., Apr 1 2017, In : Trends in Parasitology. 33, 4, p. 276-284 9 p.

Research output: Contribution to journalReview article

32 Scopus citations

Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies

Dufurrena, Q., Amjad, F. M., Scherer, P. E., Weiss, L. M., Nagajyothi, J., Roth, J., Tanowitz, H. B. & Kuliawat, R., Mar 1 2017, In : Parasitology Research. 116, 3, p. 827-838 12 p.

Research output: Contribution to journalReview article

3 Scopus citations

Insulin and glucagon: Partners for life

Holst, J. J., Holland, W. L., Gromada, J., Lee, Y. H., Unger, R. H., Yan, H., Sloop, K. W., Kieffer, T. J., Damond, N. & Herrera, P. L., Apr 1 2017, In : Endocrinology. 158, 4, p. 696-701 6 p.

Research output: Contribution to journalReview article

34 Scopus citations

Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony

Ghaben, A. L. & Scherer, P. E., Mar 3 2017, In : Circulation Research. 120, 5, p. 762-764 3 p.

Research output: Contribution to journalReview article

Sorting out adipocyte precursors and their role in physiology and disease

Hepler, C., Vishvanath, L. & Gupta, R. K., Jan 15 2017, In : Genes and Development. 31, 2, p. 127-140 14 p.

Research output: Contribution to journalReview article

45 Scopus citations

The ominous triad of adipose tissue dysfunction: Inflammation, fibrosis, and impaired angiogenesis

Crewe, C., An, Y. A. & Scherer, P. E., Jan 3 2017, In : Journal of Clinical Investigation. 127, 1, p. 74-82 9 p.

Research output: Contribution to journalReview article

141 Scopus citations
2016

Glucagon is the key factor in the development of diabetes

Lee, Y. H., Wang, M-Y., Yu, X. X. & Unger, R. H., Jul 1 2016, In : Diabetologia. 59, 7, p. 1372-1375 4 p.

Research output: Contribution to journalReview article

59 Scopus citations

Glucagon therapeutics: Dawn of a new era for diabetes care

Davidson, J. A., Holland, W. L., Roth, M. G., Wang, M-Y., Lee, Y. H., Yu, X., McCorkle, S. K., Scherer, P. E. & Unger, R. H., Oct 1 2016, In : Diabetes/Metabolism Research and Reviews. 32, 7, p. 660-665 6 p.

Research output: Contribution to journalReview article

12 Scopus citations

G protein-coupled receptors as targets for anti-diabetic therapeutics

Oh, D. & Olefsky, J. M., Mar 1 2016, In : Nature Reviews Drug Discovery. 15, 3, p. 161-172 12 p.

Research output: Contribution to journalReview article

46 Scopus citations

Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier

Zhu, Y., Crewe, C. & Scherer, P. E., Jan 27 2016, In : Science translational medicine. 8, 323

Research output: Contribution to journalReview article

14 Scopus citations

The multifaceted roles of adipose tissue - Therapeutic targets for diabetes and beyond: The 2015 banting lecture

Scherer, P. E., Jun 1 2016, In : Diabetes. 65, 6, p. 1452-1461 10 p.

Research output: Contribution to journalReview article

49 Scopus citations
2015

Adipose tissue biology in 2014: Advances in our understanding of adipose tissue homeostasis

Stern, J. H. & Scherer, P. E., Feb 16 2015, In : Nature Reviews Endocrinology. 11, 2, p. 71-72 2 p.

Research output: Contribution to journalReview article

12 Scopus citations

A new biology of diabetes revealed by leptin

Unger, R. H. & Roth, M. G., Jan 6 2015, In : Cell Metabolism. 21, 1, p. 15-20 6 p.

Research output: Contribution to journalReview article

17 Scopus citations

Leptin beyond the lipostat: Key component of blood pressure regulation

Kusminski, C. M. & Scherer, P. E., Apr 10 2015, In : Circulation research. 116, 8, p. 1293-1295 3 p.

Research output: Contribution to journalReview article

4 Scopus citations

The cell biology of fat expansion

Rutkowski, J. M., Stern, J. H. & Scherer, P. E., Jan 1 2015, In : Journal of Cell Biology. 208, 5, p. 501-512 12 p.

Research output: Contribution to journalReview article

242 Scopus citations
2014

Hyperglycemia as a risk factor for cancer progression

Ryu, T. Y., Park, J. & Scherer, P. E., 2014, In : Diabetes and Metabolism Journal. 38, 5, p. 330-336 7 p.

Research output: Contribution to journalReview article

111 Scopus citations

Improved methodologies for the study of adipose biology: Insights gained and opportunities ahead

Wang, Q. A., Scherer, P. E. & Gupta, R. K., Apr 2014, In : Journal of lipid research. 55, 4, p. 605-624 20 p.

Research output: Contribution to journalReview article

44 Scopus citations

Metabolically healthy and unhealthy obese - The 2013 stock conference report

Samocha-Bonet, D., Dixit, V. D., Kahn, C. R., Leibel, R. L., Lin, X., Nieuwdorp, M., Pietiläinen, K. H., Rabasa-Lhoret, R., Roden, M., Scherer, P. E., Klein, S. & Ravussin, E., Sep 2014, In : Obesity Reviews. 15, 9, p. 697-708 12 p.

Research output: Contribution to journalReview article

100 Scopus citations

Obesity and cancer - Mechanisms underlying tumour progression and recurrence

Park, J., Morley, T. S., Kim, M., Clegg, D. J. & Scherer, P. E., Aug 2014, In : Nature Reviews Endocrinology. 10, 8, p. 455-465 11 p.

Research output: Contribution to journalReview article

259 Scopus citations

The adipokine/ceramide axis: Key aspects of insulin sensitization

Xia, J. Y., Morley, T. S. & Scherer, P. E., Jan 2014, In : Biochimie. 96, 1, p. 130-139 10 p.

Research output: Contribution to journalReview article

28 Scopus citations
2013

Adipocytes: Impact on tumor growth and potential sites for therapeutic intervention

Hefetz-Sela, S. & Scherer, P. E., May 1 2013, In : Pharmacology and Therapeutics. 138, 2, p. 197-210 14 p.

Research output: Contribution to journalReview article

64 Scopus citations

Adiponectin, driver or passenger on the road to insulin sensitivity?

Ye, R. & Scherer, P. E., Aug 1 2013, In : Molecular Metabolism. 2, 3, p. 133-141 9 p.

Research output: Contribution to journalReview article

152 Scopus citations

Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine

Unger, R. H., Scherer, P. E. & Holland, W. L., Oct 1 2013, In : Molecular biology of the cell. 24, 19, p. 3011-3015 5 p.

Research output: Contribution to journalReview article

23 Scopus citations

Endotrophin in the tumor stroma: A new therapeutic target for breast cancer?

Park, J. & Scherer, P. E., Feb 1 2013, In : Expert Review of Anticancer Therapy. 13, 2, p. 111-113 3 p.

Research output: Contribution to journalReview article

8 Scopus citations

Fibrosis and adipose tissue dysfunction

Sun, K., Tordjman, J., Clément, K. & Scherer, P. E., Oct 1 2013, In : Cell Metabolism. 18, 4, p. 470-477 8 p.

Research output: Contribution to journalReview article

348 Scopus citations
2012

Adiponectin: Mechanistic insights and clinical implications

Turer, A. T. & Scherer, P. E., Sep 1 2012, In : Diabetologia. 55, 9, p. 2319-2326 8 p.

Research output: Contribution to journalReview article

365 Scopus citations

Adipose tissue biology and cardiomyopathy: Translational implications

Turer, A. T., Hill, J. A., Elmquist, J. K. & Scherer, P. E., Dec 2012, In : Circulation research. 111, 12, p. 1565-1577 13 p.

Research output: Contribution to journalReview article

49 Scopus citations

Glucagonocentric restructuring of diabetes: A pathophysiologic and therapeutic makeover

Unger, R. H. & Cherrington, A. D., Jan 3 2012, In : Journal of Clinical Investigation. 122, 1, p. 4-12 9 p.

Research output: Contribution to journalReview article

387 Scopus citations

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

Nagajyothi, F., Machado, F. S., Burleigh, B. A., Jelicks, L. A., Scherer, P. E., Mukherjee, S., Lisanti, M. P., Weiss, L. M., Garg, N. J. & Tanowitz, H. B., May 2012, In : Cellular Microbiology. 14, 5, p. 634-643 10 p.

Research output: Contribution to journalReview article

80 Scopus citations
2011

Adipose tissue remodeling and obesity

Sun, K., Kusminski, C. M. & Scherer, P. E., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2094-2101 8 p.

Research output: Contribution to journalReview article

893 Scopus citations

Identifying novel transcriptional components controlling energy metabolism

Gupta, R. K., Rosen, E. D. & Spiegelman, B. M., Dec 7 2011, In : Cell Metabolism. 14, 6, p. 739-745 7 p.

Research output: Contribution to journalReview article

19 Scopus citations

Paracrine and endocrine effects of adipose tissue on cancer development and progression

Park, J., Euhus, D. M. & Scherer, P. E., Aug 1 2011, In : Endocrine reviews. 32, 4, p. 550-570 21 p.

Research output: Contribution to journalReview article

185 Scopus citations
67 Scopus citations
2010

Adipokines as novel biomarkers and regulators of the metabolic syndrome.

Deng, Y. & Scherer, P. E., Nov 2010, In : Annals of the New York Academy of Sciences. 1212, p. E1-E19

Research output: Contribution to journalReview article

309 Scopus citations

Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity

Unger, R. H. & Scherer, P. E., Jun 1 2010, In : Trends in Endocrinology and Metabolism. 21, 6, p. 345-352 8 p.

Research output: Contribution to journalReview article

259 Scopus citations

Lipid homeostasis, lipotoxicity and the metabolic syndrome

Unger, R. H., Clark, G. O., Scherer, P. E. & Orci, L., Mar 1 2010, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1801, 3, p. 209-214 6 p.

Research output: Contribution to journalReview article

354 Scopus citations

Paracrinology of islets and the paracrinopathy of diabetes

Unger, R. H. & Orci, L., Sep 14 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16009-16012 4 p.

Research output: Contribution to journalReview article

155 Scopus citations
2009

Adipocyte metabolism and obesity

Attie, A. D. & Scherer, P. E., Apr 1 2009, In : Journal of lipid research. 50, SUPPL., p. S395-S399

Research output: Contribution to journalReview article

132 Scopus citations

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

Shetty, S., Kusminski, C. M. & Scherer, P. E., May 1 2009, In : Trends in Pharmacological Sciences. 30, 5, p. 234-239 6 p.

Research output: Contribution to journalReview article

167 Scopus citations