Medical Dermatology

Research output

Research output per year 2002 2006 2019

• 25 Article
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2019

  Double-Stranded RNA Sensing Determines Epithelial Cell Identity

  Liao Ph.D., C. P., Tchegnon, E. & Le, L. Q., Jan 2019, In: Journal of Investigative Dermatology. 139, 1, p. 17-19 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Double-Stranded RNA 100%
  • Epithelial Cells 50%
  • Keratinocytes 45%
  • Keratin-9 44%
  • Skin 38%
• 2018

  Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

  Liao, C. P., Booker, R. C., Brosseau, J. P., Chen, Z., Mo, J., Tchegnon, E., Wang, Y., Clapp, D. W. & Le, L. Q., Jul 2 2018, In: Journal of Clinical Investigation. 128, 7, p. 2848-2861 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurofibroma 100%
  • Tumor Microenvironment 79%
  • Carcinogenesis 58%
  • Inflammation 45%
  • Mast Cells 41%
  105 Scopus citations

• NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation

  Brosseau, J. P., Liao Ph.D., C. P., Wang, Y., Ramani, V., Vandergriff, T. W., Lee, M., Patel, A., Ariizumi, K. & Le, L. Q., Dec 1 2018, In: Nature communications. 9, 1, 5014.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurofibromatosis 1 100%
  • Refractory 85%
  • tumors 78%
  • Disorder 70%
  • Mutation 69%
  38 Scopus citations
• 2017

  Identification of hair shaft progenitors that create a niche for hair pigmentation

  Liao, C. P., Booker, R. C., Morrison, S. J. & Le, L. Q., Apr 15 2017, In: Genes and Development. 31, 8, p. 744-756 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pigmentation 100%
  • Melanocytes 99%
  • Stem Cell Factor 53%
  • Stem Cells 48%
  • Hair Follicle 25%
  40 Scopus citations
• 2016

  The role of nerve microenvironment for neurofibroma development

  Liao, C. P., Pradhan, S., Chen, Z., Patel, A. J., Booker, R. C. & Le, L. Q., 2016, In: Oncotarget. 7, 38, p. 61500-61508 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurofibroma 100%
  • Neurofibromatosis 1 40%
  • Peripheral Nerves 32%
  • Schwann Cells 24%
  • Peripheral Nervous System Neoplasms 17%
  26 Scopus citations
• 2015

  An interconnected hierarchical model of cell death regulation by the BCL-2 family

  Chen, H. C., Kanai, M., Inoue-Yamauchi, A., Tu, H. C., Huang, Y., Ren, D., Kim, H., Takeda, S., Reyna, D. E., Chan, P. M., Ganesan, Y. T., Liao, C. P., Gavathiotis, E., Hsieh, J. J. & Cheng, E. H., Oct 3 2015, In: Nature cell biology. 17, 10, p. 1270-1281 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Death 100%
  • Apoptosis 80%
  • Puma 68%
  • Noxae 65%
  • Mitochondria 36%
  216 Scopus citations
• 2014

  BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through bim induction

  Patel, A., Liao, C. P., Chen, Z., Liu, C., Wang, Y. & Le, L., 2014, In: Cell Reports. 6, 1, p. 81-92 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurofibrosarcoma 100%
  • Neurofibromatosis 1 91%
  • Apoptosis 45%
  • Molecule 25%
  • Sarcoma 10%
  63 Scopus citations

• Cells of Origin in the Embryonic Nerve Roots for NF1-Associated Plexiform Neurofibroma

  Chen, Z., Liu, C., Patel, A. J., Liao, C. P., Wang, Y. & Le, L. Q., Nov 10 2014, In: Cancer Cell. 26, 5, p. 695-706 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Plexiform Neurofibroma 100%
  • Neurofibroma 63%
  • Neoplasms 21%
  • Neurofibromatosis 1 19%
  • Preclinical Drug Evaluations 19%
  78 Scopus citations
• 2011

  Defective nitric oxide production by alveolar macrophages during Pneumocystis pneumonia

  Lasbury, M. E., Liao, C. P., Hage, C. A., Durant, P. J., Tschang, D., Wang, S. H., Zhang, C. & Lee, C. H., Apr 1 2011, In: American journal of respiratory cell and molecular biology. 44, 4, p. 540-547 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis Pneumonia 100%
  • Alveolar Macrophages 89%
  • Nitric Oxide 76%
  • Pneumocystis 61%
  • Nitric Oxide Synthase Type II 59%
  9 Scopus citations
• 2010

  Downregulation of PU.1 leads to decreased expression of dectin-1 in alveolar macrophages during Pneumocystis pneumonia

  Zhang, C., Wang, S. H., Liao, C. P., Shao, S., Lasbury, M. E., Durant, P. J. & Lee, C. H., Mar 2010, In: Infection and immunity. 78, 3, p. 1058-1065 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis 100%
  • dectin 1 95%
  • Pneumocystis Pneumonia 77%
  • Alveolar Macrophages 69%
  • pneumonia 67%
  18 Scopus citations

• Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages

  Cheng, B. H., Liu, Y., Xuei, X., Liao, C. P., Lu, D., Lasbury, M. E., Durant, P. J. & Lee, C. H., 2010, In: BMC microbiology. 10, 103.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis Infections 100%
  • Alveolar Macrophages 73%
  • Pneumocystis 58%
  • Gene Expression 39%
  • Pneumocystis Pneumonia 35%
  12 Scopus citations
• 2009

  Effects of decreased calmodulin protein on the survival mechanisms of alveolar macrophages during Pneumocystis pneumonia

  Lasbury, M. E., Durant, P. J., Liao, C. P. & Lee, C. H., Aug 2009, In: Infection and immunity. 77, 8, p. 3344-3354 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis 100%
  • Pneumocystis Pneumonia 77%
  • granulocyte-macrophage colony-stimulating factor 75%
  • phosphatidylinositol 3-kinase 69%
  • Alveolar Macrophages 69%
  6 Scopus citations

• Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages

  Liao, C. P., Lasbury, M. E., Wang, S. H., Zhang, C., Durant, P. J., Murakami, Y., Matsufuji, S. & Lee, C. H., Mar 20 2009, In: Journal of Biological Chemistry. 284, 12, p. 8174-8184 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis 100%
  • Polyamines 77%
  • Alveolar Macrophages 72%
  • Polyamine 70%
  • Pneumocystis Pneumonia 48%
  20 Scopus citations

• Polyamine transport as a target for treatment of Pneumocystis pneumonia

  Liao, C. P., Phanstiel IV, O., Lasbury, M. E., Zhang, C., Shao, S., Durant, P. J., Cheng, B. H. & Lee, C. H., Dec 2009, In: Antimicrobial agents and chemotherapy. 53, 12, p. 5259-5264 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pneumocystis Pneumonia 100%
  • Polyamines 95%
  • Ants 82%
  • Diamines 71%
  • Alveolar Macrophages 66%
  7 Scopus citations
• 2008

  Decreased inflammatory response in Toll-like receptor 2 knockout mice is associated with exacerbated Pneumocystis pneumonia

  Wang, S. H., Zhang, C., Lasbury, M. E., Liao, C. P., Durant, P. J., Tschang, D. & Lee, C. H., Apr 2008, In: Microbes and Infection. 10, 4, p. 334-341 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Toll-Like Receptor 2 100%
  • Pneumocystis Pneumonia 98%
  • Mouse Tlr2 protein 92%
  • Knockout Mice 72%
  • Pneumocystis 40%
  19 Scopus citations
• 2006

  Alterations in surfactant protein A form and clearance during Pneumocystis pneumonia

  Lasbury, M. E., Durant, P. J., Wang, S. H., Zhang, C., Liao, C. P., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S119-S121

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Caspase-9 as a target for Pneumocystis pneumonia therapy

  Lasbury, M. E., Wang, S. H., Zhang, C., Liao, C. P., Durant, P. J., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S138-S139

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Expression and activation of complement protein and alveolar damage during pneumocystis pneumonia

  Lasbury, M. E., Durant, P. J., Tschang, D., Wang, S. H., Zhang, C., Liao, C. P. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S136-S137

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• GM-CSF expression in the lung during Pneumocystis pneumonia

  Lasbury, M. E., Durant, P. J., Wang, S. H., Zhang, C., Liao, C. P., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S124-S126

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Inflammatory cells are sources of polyamines that induce alveolar macrophage to undergo apoptosis during Pneumocystis pneumonia

  Liao, C. P., Lasbury, M. E., Wang, S. H., Zhang, C., Durant, P. J., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S134-S135

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Survival pathway signal transduction is reduced in alveolar macrophages during Pneumocystis pneumonia

  Lasbury, M. E., Ray, C. A., Durant, P. J., Wang, S. H., Zhang, C., Liao, C. P., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S130-S131

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Syndecan-1 expression in the lung during Pneumocystis infection

  Wang, S. H., Zhang, C., Liao, C. P., Lasbury, M. E., Durant, P. J., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S122-S123

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Toll-like receptor 2 knockout reduces lung inflammation during Pneumocystis pneumonia but has no effect on phagocytosis of Pneumocystis organisms by alveolar macrophages

  Zhang, C., Wang, S. H., Liao, C. P., Lasbury, M. E., Durant, P. J., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S132-S133

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Toll-like receptor 2 mediates alveolar macrophage response to Pneumocystis murina

  Zhang, C., Wang, S. H., Lasbury, M. E., Tschang, D., Liao, C. P., Durant, P. J. & Lee, C. H., Mar 2006, In: Infection and immunity. 74, 3, p. 1857-1864 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pneumocystis 100%
  • Toll-like receptor 2 98%
  • Murinae 93%
  • Toll-Like Receptor 2 78%
  • Alveolar Macrophages 69%
  59 Scopus citations

• Transforming growth factor-β activation and signaling in the alveolar environment during Pneumocystis pneumonia

  Ray, C. A., Lasbury, M. E., Durant, P. J., Wang, S. H., Zhang, C., Liao, C. P., Tschang, D. & Lee, C. H., Nov 2006, In: Journal of Eukaryotic Microbiology. 53, SUPPL. 1, p. S127-S129

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations
• 2002

  Analysis of the baseplate region of phage AR1 that specifically infects Escherichia coli O157:H7

  Liao, C. P. & Syu, W. J., Dec 2002, In: Journal of Microbiology, Immunology and Infection. 35, 4, p. 269-271 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Escherichia coli O157 100%
  • Bacteriophages 77%
  • Genes 31%
  • Bacteria 13%
  3 Scopus citations