Research Output 1967 2019

Filter
Review article
Review article

Adaptation of Candida albicans During Gastrointestinal Tract Colonization

Mishra, A. A. & Koh, A., Sep 1 2018, In : Current Clinical Microbiology Reports. 5, 3, p. 165-172 8 p.

Research output: Contribution to journalReview article

Candida albicans
Gastrointestinal Tract
Immune System
Microbiota
Virulence Factors
26 Citations (Scopus)

Autophagy and the cell biology of age-related disease

Leidal, A. M., Levine, B. & Debnath, J., Dec 1 2018, In : Nature Cell Biology. 20, 12, p. 1338-1348 11 p.

Research output: Contribution to journalReview article

Autophagy
Cell Biology
Homeostasis
Health
45 Citations (Scopus)

Autophagy balances inflammation in innate immunity

Deretic, V. & Levine, B., Feb 1 2018, In : Autophagy. 14, 2, p. 243-251 9 p.

Research output: Contribution to journalReview article

Autophagy
Innate Immunity
Inflammation
Immunity
Inflammasomes
83 Citations (Scopus)

Biological Functions of Autophagy Genes: A Disease Perspective

Levine, B. & Kroemer, G., Jan 10 2019, In : Cell. 176, 1-2, p. 11-42 32 p.

Research output: Contribution to journalReview article

Autophagy
Genes
Neurodegenerative diseases
Protein Deficiency
Aging of materials
1 Citation (Scopus)

Cancer Immune Checkpoint Inhibitor Therapy and the Gut Microbiota

Frankel, A. E., Deshmukh, S., Reddy, A., Lightcap, J., Hayes, M., McClellan, S., Singh, S., Rabideau, B., Glover, T. G., Roberts, B. & Koh, A., Apr 1 2019, In : Integrative Cancer Therapies. 18

Research output: Contribution to journalReview article

Open Access
Tumor Microenvironment
Immunosuppressive Agents
Immunotherapy
Immune System
Bacteria
7 Citations (Scopus)

CDK9: a signaling hub for transcriptional control

Bacon, C. W. & D'orso, I., Mar 15 2019, In : Transcription. 10, 2, p. 57-75 19 p.

Research output: Contribution to journalReview article

Cyclin-Dependent Kinase 9
Transcription
Elongation
Small Nucleolar RNA
Dichlororibofuranosylbenzimidazole
4 Citations (Scopus)

Enterohemorrhagic Escherichia coli outwits hosts through sensing small molecules

Carlson-Banning, K. M. & Sperandio, V., Feb 1 2018, In : Current Opinion in Microbiology. 41, p. 83-88 6 p.

Research output: Contribution to journalReview article

Enterohemorrhagic Escherichia coli
Metabolomics
Microbiota
Virulence
Gastrointestinal Tract
246 Citations (Scopus)

Interactions between the microbiota and pathogenic bacteria in the gut

Baümler, A. J. & Sperandio, V., Jul 6 2016, In : Nature. 535, 7610, p. 85-93 9 p.

Research output: Contribution to journalReview article

Microbiota
Bacteria
Communicable Diseases
Virulence
Respiration
40 Citations (Scopus)

Making Mouse Models That Reflect Human Immune Responses

Tao, L. & Reese, T. A., Mar 1 2017, In : Trends in Immunology. 38, 3, p. 181-193 13 p.

Research output: Contribution to journalReview article

Immune System
Specific Pathogen-Free Organisms
Environmental Exposure
Infection
310 Citations (Scopus)

Molecular definitions of autophagy and related processes

Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo-San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I., Cuervo, A. M., Debnath, J., Deretic, V., Dikic, I., Eskelinen, E. L., Fimia, G. M., Fulda, S., Gewirtz, D. A., Green, D. R., Hansen, M. & 34 others, Harper, J. W., Jäättelä, M., Johansen, T., Juhasz, G., Kimmelman, A. C., Kraft, C., Ktistakis, N. T., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Münz, C., Murphy, L. O., Penninger, J. M., Piacentini, M., Reggiori, F., Rubinsztein, D. C., Ryan, K. M., Santambrogio, L., Scorrano, L., Simon, A. K., Simon, H. U., Simonsen, A., Tavernarakis, N., Tooze, S. A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q. & Kroemer, G., Jul 3 2017, In : EMBO Journal. 36, 13, p. 1811-1836 26 p.

Research output: Contribution to journalReview article

Autophagy
Machinery
Research
420 Citations (Scopus)

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 others, Blomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

Terminology
Cell Death
Apoptosis
Cell Aging
Autophagy
4 Citations (Scopus)

Pathobiology and immunobiology of Acanthamoeba keratitis: Insights from animal models

Neelam, S. & Niederkorn, J. Y., Jun 1 2017, In : Yale Journal of Biology and Medicine. 90, 2, p. 261-268 8 p.

Research output: Contribution to journalReview article

Acanthamoeba Keratitis
Animals
Acanthamoeba
Animal Models
Contact lenses
198 Citations (Scopus)

Pharmacological modulation of autophagy: Therapeutic potential and persisting obstacles

Galluzzi, L., Bravo-San Pedro, J. M., Levine, B., Green, D. R. & Kroemer, G., Jul 1 2017, In : Nature Reviews Drug Discovery. 16, 7, p. 487-511 25 p.

Research output: Contribution to journalReview article

Autophagy
Pharmacology
Therapeutics
Heart Neoplasms
Homeostasis
143 Citations (Scopus)

Polypeptides of Treponema pallidum: Progress toward understanding their structural, functional, and immunologic roles

Norris, S. J., Axelsen, N. H., Bassford, P. J., Baughn, R. E., Hanff, P. A., Hindersson, P., Isaacs, R. D., Lovett, M. A., Blanco, D. R., Larsen, S. A., Cox, D. L., Lukehart, S. A., Baker-Zander, S. A., Miller, J. N., Muller, F., Moskophidis, M. A., Noordhoek, G. T., Norgard, M. V. & Penn, C. W., Jan 1 1993, In : Microbiological Reviews. 57, 3, p. 750-779 30 p.

Research output: Contribution to journalReview article

Treponema pallidum
Peptides
Proteins
Syphilis
Spirochaetales
2 Citations (Scopus)
Transplants
Neoplastic Stem Cells
Graft vs Host Disease
Stem cells
Grafts
32 Citations (Scopus)

Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae

Prokesch, B. C., TeKippe, M., Kim, J., Raj, P., TeKippe, E. M. E. & Greenberg, D. E., 2016, In : The Lancet Infectious Diseases. 16, 9, p. e190-e195

Research output: Contribution to journalReview article

Klebsiella pneumoniae
Osteomyelitis
Pneumonia
Infection
Teaching Rounds
49 Citations (Scopus)

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

Boland, B., Yu, W. H., Corti, O., Mollereau, B., Henriques, A., Bezard, E., Pastores, G. M., Rubinsztein, D. C., Nixon, R. A., Duchen, M. R., Mallucci, G. R., Kroemer, G., Levine, B., Eskelinen, E. L., Mochel, F., Spedding, M., Louis, C., Martin, O. R. & Millan, M. J., Sep 1 2018, In : Nature Reviews Drug Discovery. 17, 9, p. 660-688 29 p.

Research output: Contribution to journalReview article

Neurodegenerative Diseases
Frontotemporal Dementia
Proteins
Huntington Disease
Autophagy
11 Citations (Scopus)

Recent advances in antiviral interferon-stimulated gene biology

Schoggins, J. W., Jan 1 2018, In : F1000Research. 7, 309.

Research output: Contribution to journalReview article

Interferons
Antiviral Agents
Genes
Pathogens
Screening
22 Citations (Scopus)

Shared and Distinct Functions of Type I and Type III Interferons

Lazear, H. M., Schoggins, J. W. & Diamond, M. S., Apr 16 2019, In : Immunity. 50, 4, p. 907-923 17 p.

Research output: Contribution to journalReview article

Interferon Type I
Interferons
Virus Activation
Virus Diseases
Infection Control
1 Citation (Scopus)

Strength in numbers: Mechanisms of viral co-infection

Aguilera, E. R. & Pfeiffer, J. K., May 1 2019, In : Virus Research. 265, p. 43-46 4 p.

Research output: Contribution to journalReview article

RNA Viruses
Virus Diseases
Coinfection
Viruses
Defective Viruses

The gut microbiota in transplant patients

Chong, P. P. E. & Koh, A., Jan 1 2019, (Accepted/In press) In : Blood Reviews. 100614.

Research output: Contribution to journalReview article

Transplants
Hematopoietic Stem Cells
Dysbiosis
Gastrointestinal Microbiome
Probiotics
6 Citations (Scopus)
Microbiota
Hematopoietic Stem Cells
Transplants
Infection
Neoplasms
15 Citations (Scopus)

Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies

Hasan, M. & Yan, N., Sep 1 2016, In : Pharmacological Research. 111, p. 336-342 7 p.

Research output: Contribution to journalReview article

Autoimmune Diseases
Interferon Type I
Private Sector
Protein-Serine-Threonine Kinases
Interferons
14 Citations (Scopus)

Transcription elongation control by the 7SK snRNP complex: Releasing the pause

McNamara, R. P., Bacon, C. W. & D'Orso, I., Aug 17 2016, In : Cell Cycle. 15, 16, p. 2115-2123 9 p.

Research output: Contribution to journalReview article

Positive Transcriptional Elongation Factor B
Small Nuclear Ribonucleoproteins
Genetic Promoter Regions
Phosphotransferases
Peptide Elongation Factors
43 Citations (Scopus)

Treponema pallidum, the syphilis spirochete: Making a living as a stealth pathogen

Radolf, J. D., Deka, R. K., Anand, A., Šmajs, D., Norgard, M. V. & Yang, X. F., Dec 1 2016, In : Nature Reviews Microbiology. 14, 12, p. 744-759 16 p.

Research output: Contribution to journalReview article

Treponema pallidum
Spirochaetales
Syphilis
Immune Evasion
Globus Pallidus