Research output per year
Research output per year
- 37 results
Search results
-
2022
Genome-Wide CRISPR Screening to Identify Mammalian Factors that Regulate Intron Retention
Scarborough, A. M., Govindan, A. & Conrad, N. K., 2022, Methods in Molecular Biology. Humana Press Inc., p. 263-284 22 p. (Methods in Molecular Biology; vol. 2537).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2021
SAM homeostasis is regulated by CFIm- mediated splicing of MAT2A
Scarborough, A. M., Flaherty, J. N., Hunter, O. V., Liu, K., Kumar, A., Xing, C., Tu, B. P. & Conrad, N. K., May 2021, In: eLife. 10, e64930.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2020
Kaposi’s sarcoma-associated herpesvirus fine-tunes the temporal expression of late genes by manipulating a host RNA quality control pathway
Ruiz, J. C., Devlin, A. M., Kim, J. & Conrad, N. K., Jul 1 2020, In: Journal of virology. 94, 14, e00287-20.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2019
Kaposi’s sarcoma-associated herpesvirus ORF57 protein protects viral transcripts from specific nuclear RNA decay pathways by preventing hMTR4 recruitment
Ruiz, J. C., Hunter, O. V. & Conrad, N. K., Feb 2019, In: PLoS pathogens. 15, 2, e1007596.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2018
Balance between MAT2A intron detention and splicing is determined cotranscriptionally
Pendleton, K. E., Park, S. K., Hunter, O. V., Bresson, S. M. & Conrad, N. K., Jun 2018, In: RNA. 24, 6, p. 778-786 9 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Influenza virus NS1 protein-RNA interactome reveals intron targeting
Zhang, L., Wang, J., Muñoz-Moreno, R., Kim, M., Sakthivel, R., Mo, W., Shao, D., Anantharaman, A., García-Sastre, A., Conrad, N. K. & Fontoura, B. M., Dec 1 2018, In: Journal of virology. 92, 24, e0163418.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor
Doxtader, K. A., Wang, P., Scarborough, A. M., Seo, D., Conrad, N. K. & Nam, Y., Sep 20 2018, In: Molecular cell. 71, 6, p. 1001-1011.e4Research output: Contribution to journal › Article › peer-review
Open Access135 Scopus citations -
2017
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis
Park, S. K., Zhou, X., Pendleton, K. E., Hunter, O. V., Kohler, J. J., O'Donnell-Mendell, K. A. & Conrad, N. K., Aug 1 2017, In: Cell Reports. 20, 5, p. 1088-1099 12 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins
Anantharaman, A., Tripathi, V., Khan, A., Yoon, J. H., Singh, D. K., Gholamalamdari, O., Guang, S., Ohlson, J., Wahlstedt, H., Öhman, M., Jantsch, M. F., Conrad, N. K., Ma, J., Gorospe, M., Prasanth, S. G. & Prasanth, K. V., Apr 20 2017, In: Nucleic acids research. 45, 7, p. 4189-4201 13 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Poly(A) tail length regulates PABPC1 expression to tune translation in the heart
Chorghade, S., Seimetz, J., Emmons, R., Yang, J., Bresson, S. M., de Lisio, M., Parise, G., Conrad, N. K. & Kalsotra, A., Jun 27 2017, In: eLife. 6, e24139.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
Pendleton, K. E., Chen, B., Liu, K., Hunter, O. V., Xie, Y., Tu, B. P. & Conrad, N. K., May 18 2017, In: Cell. 169, 5, p. 824-835.e14Research output: Contribution to journal › Article › peer-review
Open Access696 Scopus citations -
2016
New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA
Conrad, N. K., Jan 2 2016, In: Virus Research. 212, p. 53-63 11 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
2015
Canonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs
Bresson, S. M., Hunter, O. V., Hunter, A. C. & Conrad, N. K., 2015, In: PLoS genetics. 11, 10, e1005610.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy
Stubbs, S. H. & Conrad, N. K., Sep 1 2015, In: Nucleic acids research. 43, 1, p. 504-519 16 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
HITS-CLIP Analysis Uncovers a Link between the Kaposi’s Sarcoma-Associated Herpesvirus ORF57 Protein and Host Pre-mRNA Metabolism
Sei, E., Wang, T., Hunter, O. V., Xie, Y. & Conrad, N. K., 2015, In: PLoS pathogens. 11, 2, e1004652.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2014
Analysis of RNA-protein interactions by cell mixing
Stubbs, S. H. & Conrad, N. K., 2014, Laboratory Methods in Enzymology: Protein Part B. Academic Press Inc., p. 67-80 14 p. (Methods in Enzymology; vol. 539).Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
The emerging role of triple helices in RNA biology
Conrad, N. K., Jan 2014, In: Wiley Interdisciplinary Reviews: RNA. 5, 1, p. 15-29 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access62 Scopus citations -
UV cross-linking of interacting RNA and protein in cultured cells
Sei, E. & Conrad, N. K., 2014, Laboratory Methods in Enzymology: Protein Part B. Academic Press Inc., p. 53-66 14 p. (Methods in Enzymology; vol. 539).Research output: Chapter in Book/Report/Conference proceeding › Chapter
11 Scopus citations -
2013
Chromatin Immunoprecipitation and Microarray Analysis Suggest Functional Cooperation between Kaposi's Sarcoma-Associated Herpesvirus ORF57 and K-bZIP
Hunter, O. V., Sei, E., Blake Richardson, R. & Conrad, N. K., Apr 2013, In: Journal of virology. 87, 7, p. 4005-4016 12 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay
Bresson, S. M. & Conrad, N. K., Oct 2013, In: PLoS genetics. 9, 10, e1003893.Research output: Contribution to journal › Article › peer-review
93 Scopus citations -
2012
Chemical Reporters for Monitoring RNA Synthesis and Poly(A) Tail Dynamics
Grammel, M., Hang, H. & Conrad, N. K., May 2012, In: ChemBioChem. 13, 8, p. 1112-1115 4 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Viral factors reveal a role for REF/Aly in nuclear RNA stability
Stubbs, S. H., Hunter, O. V., Hoover, A. & Conrad, N. K., Apr 2012, In: Molecular and cellular biology. 32, 7, p. 1260-1270 11 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2011
Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity
Sei, E. & Conrad, N. K., Oct 25 2011, In: Virology. 419, 2, p. 107-116 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
2010
Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding rna from cellular RNA decay pathways
Sahin, B. B., Patel, D. & Conrad, N. K., Mar 2010, In: PLoS pathogens. 6, 3, e1000799.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
2009
Chapter 6 Posttranscriptional Gene Regulation in Kaposi's Sarcoma-Associated Herpesvirus
Conrad, N. K., 2009, In: Advances in Applied Microbiology. 68, p. 241-261 21 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2008
Chapter 15 Co-Immunoprecipitation Techniques for Assessing RNA-Protein Interactions In Vivo
Conrad, N. K., 2008, In: Methods in Enzymology. 449, C, p. 317-342 26 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2007
Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail
Conrad, N. K., Shu, M. D., Uyhazi, K. E. & Steitz, J. A., Jun 19 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 25, p. 10412-10417 6 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2006
Identification of a Rapid Mammalian Deadenylation-Dependent Decay Pathway and Its Inhibition by a Viral RNA Element
Conrad, N. K., Mili, S., Marshall, E. L., Shu, M. D. & Steitz, J. A., Dec 28 2006, In: Molecular cell. 24, 6, p. 943-953 11 p.Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
The challenge of viral snRNPs
Conrad, N. K., Fok, V., Cazalla, D., Borah, S. & Steitz, J. A., 2006, In: Cold Spring Harbor symposia on quantitative biology. 71, p. 377-384 8 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2005
A Kaposi's sarcoma virus RNA element that increases the nuclear abundance of intronless transcripts
Conrad, N. K. & Steitz, J. A., May 18 2005, In: EMBO Journal. 24, 10, p. 1831-1841 11 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
2001
RNA-binding protein Nrd1 directs poly(A)-independent 3′-end formation of RNA polymerase II transcripts
Steinmetz, E. J., Conrad, N. K., Brow, D. A. & Corden, J. L., Sep 20 2001, In: Nature. 413, 6853, p. 327-331 5 p.Research output: Contribution to journal › Article › peer-review
297 Scopus citations -
2000
A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II
Conrad, N. K., Wilson, S. M., Steinmetz, E. J., Patturajan, M., Brow, D. A., Swanson, M. S. & Corden, J. L., Feb 2000, In: Genetics. 154, 2, p. 557-571 15 p.Research output: Contribution to journal › Article › peer-review
113 Scopus citations -
1999
The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4
Kubo, A., Nakagawa, K., Varma, R. K., Conrad, N. K., Cheng, J. Q., Lee, W. C., Testa, J. R., Johnson, B. E., Kaye, F. J. & Kelley, M. J., Dec 1999, In: Clinical Cancer Research. 5, 12, p. 4279-4286 8 p.Research output: Contribution to journal › Article › peer-review
72 Scopus citations -
Yeast carboxyl-terminal domain kinase I positively and negatively regulates RNA polymerase II carboxyl-terminal domain phosphorylation
Patturajan, M., Conrad, N. K., Bregman, D. B. & Corden, J. L., Sep 24 1999, In: Journal of Biological Chemistry. 274, 39, p. 27823-27828 6 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
1996
Genetic analysis of second primary lung cancers in patients surviving small cell lung cancer
Kelley, M. J., Nakagawa, K., Conrad, N. K., LeRiche, J., Murray, N., Lee, J. S., Ro, J. Y., Shaw, E. G., Tucker, M. A. & Johnson, B. E., Jul 1996, In: Clinical Cancer Research. 2, 7, p. 1103-1105 3 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
1995
Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage
Nakagawa, K., Conrad, N. K., Williams, J. P., Johnson, B. E. & Kelley, M. J., Nov 2 1995, In: Oncogene. 11, 9, p. 1842-1851 10 p.Research output: Contribution to journal › Article › peer-review
78 Scopus citations -
TP53 and RAS mutations in metachronous tumors from patients with cancer of the upper aerodigestive tract
Yang, H. K., Linnoila, R. I., Conrad, N. K., Krasna, M. J., Aisner, S. C., Johnson, B. E. & Kelley, M. J., Aug 22 1995, In: International Journal of Cancer. 64, 4, p. 229-233 5 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations