Microbiology - Schoggins Lab - Administration

Research Output

2020

A sensitive yellow fever virus entry reporter identifies valosin-containing protein (VCP/P97) as an essential host factor for flavivirus uncoating

Ramanathan, H. N., Zhang, S., Douam, F., Mar, K. B., Chang, J., Yang, P. L., Schoggins, J. W., Ploss, A. & Lindenbach, B. D., Mar 1 2020, In : mBio. 11, 2, e00467-20.

Research output: Contribution to journalArticle

Open Access

Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol

Abrams, M. E., Johnson, K. A., Perelman, S. S., Zhang, L. S., Endapally, S., Mar, K. B., Thompson, B. M., McDonald, J. G., Schoggins, J. W., Radhakrishnan, A. & Alto, N. M., Jan 1 2020, (Accepted/In press) In : Nature microbiology.

Research output: Contribution to journalArticle

2019

A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB

Liu, Z., Mar, K. B., Hanners, N. W., Perelman, S. S., Kanchwala, M., Xing, C., Schoggins, J. W. & Alto, N. M., Jan 1 2019, In : Nature.

Research output: Contribution to journalLetter

3 Scopus citations

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape

Hubel, P., Urban, C., Bergant, V., Schneider, W. M., Knauer, B., Stukalov, A., Scaturro, P., Mann, A., Brunotte, L., Hoffmann, H. H., Schoggins, J. W., Schwemmle, M., Mann, M., Rice, C. M. & Pichlmair, A., Apr 1 2019, In : Nature immunology. 20, 4, p. 493-502 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Comparative analysis of viral entry for Asian and African lineages of Zika virus

Rinkenberger, N. & Schoggins, J. W., Jul 1 2019, In : Virology. 533, p. 59-67 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Interferon-Stimulated Genes: What Do They All Do?

Schoggins, J. W., Sep 29 2019, In : Annual Review of Virology. 6, p. 567-584 18 p.

Research output: Contribution to journalArticle

13 Scopus citations

Shared and Distinct Functions of Type I and Type III Interferons

Lazear, H. M., Schoggins, J. W. & Diamond, M. S., Apr 16 2019, In : Immunity. 50, 4, p. 907-923 17 p.

Research output: Contribution to journalReview article

53 Scopus citations
2018

A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication

Richardson, R. B., Ohlson, M. B., Eitson, J. L., Kumar, A., McDougal, M. B., Boys, I. N., Mar, K. B., De La Cruz-Rivera, P. C., Douglas, C., Konopka, G., Xing, C. & Schoggins, J. W., Nov 1 2018, In : Nature Microbiology. 3, 11, p. 1214-1223 10 p.

Research output: Contribution to journalLetter

21 Scopus citations

Genetic variation at IFNL4 influences extrahepatic interferon-stimulated gene expression in chronic HCV patients

Rosenberg, B. R., Freije, C. A., Imanaka, N., Chen, S. T., Eitson, J. L., Caron, R., Uhl, S. A., Zeremski, M., Talal, A., Jacobson, I. M., Rice, C. M. & Schoggins, J. W., Feb 15 2018, In : Journal of Infectious Diseases. 217, 4, p. 650-655 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step

Mar, K. B., Rinkenberger, N. R., Boys, I. N., Eitson, J. L., McDougal, M. B., Richardson, R. B. & Schoggins, J. W., Dec 1 2018, In : Nature communications. 9, 1, 3603.

Research output: Contribution to journalArticle

14 Scopus citations

Mucolipin-2 cation channel increases trafficking efficiency of endocytosed viruses

Rinkenberger, N. & Schoggins, J. W., Jan 1 2018, In : mBio. 9, 1, e02314-17.

Research output: Contribution to journalArticle

9 Scopus citations

Recent advances in antiviral interferon-stimulated gene biology

Schoggins, J. W., Jan 1 2018, In : F1000Research. 7, 309.

Research output: Contribution to journalReview article

13 Scopus citations

The IFN response in bats displays distinctive ifn-stimulated gene expression kinetics with atypical RNASEL induction

De La Cruz-Rivera, P. C., Kanchwala, M., Liang, H., Kumar, A., Wang, L. F., Xing, C. & Schoggins, J. W., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 209-217 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2017

The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry

Lipovsky, A., Erden, A., Kanaya, E., Zhang, W., Crite, M., Bradfield, C., MacMicking, J., DiMaio, D., Schoggins, J. W. & Iwasaki, A., Nov 1 2017, In : Journal of General Virology. 98, 11, p. 2821-2836 16 p., 000954.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection

Perelman, S. S., Abrams, M. E., Eitson, J. L., Chen, D., Jimenez, A., Mettlen, M., Schoggins, J. W. & Alto, N. M., Dec 21 2016, In : PLoS Pathogens. 12, 12, e1006102.

Research output: Contribution to journalArticle

8 Scopus citations

Identification of Interferon-Stimulated Genes with Antiretroviral Activity

Kane, M., Zang, T. M., Rihn, S. J., Zhang, F., Kueck, T., Alim, M., Schoggins, J., Rice, C. M., Wilson, S. J. & Bieniasz, P. D., Sep 14 2016, In : Cell Host and Microbe. 20, 3, p. 392-405 14 p.

Research output: Contribution to journalArticle

56 Scopus citations

NLRX1 Helps HIV Avoid a STING Operation

Mar, K. B. & Schoggins, J. W., Apr 13 2016, In : Cell Host and Microbe. 19, 4, p. 430-431 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects

Hanners, N. W., Eitson, J. L., Usui, N., Richardson, R. B., Wexler, E. M., Konopka, G. & Schoggins, J. W., Jun 14 2016, In : Cell Reports. 15, 11, p. 2315-2322 8 p.

Research output: Contribution to journalArticle

69 Scopus citations
2015

A phospholipase linkAGE to SARS susceptibility

Schoggins, J. W., Oct 19 2015, In : Journal of Experimental Medicine. 212, 11, 1 p.

Research output: Contribution to journalComment/debate

A Sense of Self: RIG-I's Tolerance to Host RNA

Schoggins, J. W., Jul 21 2015, In : Immunity. 43, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Erratum: A diverse range of gene products are effectors of the type I interferon antiviral response (Nature (2015) 472 (481-485) (DOI:10.1038/nature09907))

Schoggins, J. W., Wilson, S. J., Panis, M., Murphy, M. Y., Jones, C. T., Bieniasz, P. & Rice, C. M., Sep 3 2015, In : Nature. 525, 7567, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

Erratum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity (Nature (2014) 505 (691-695) (DOI:10.1038/nature12862))

Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., Dabelic, R., Manicassamy, B., Aitchison, J. D., Aderem, A., Elliott, R. M., García-Sastre, A., Racaniello, V., Snijder, E. J., Yokoyama, W. M., Diamond, M. S. & 2 others, Virgin, H. W. & Rice, C. M., Sep 3 2015, In : Nature. 525, 7567, p. 144 1 p.

Research output: Contribution to journalArticle

3 Scopus citations

Viruses carry antiviral cargo

Schoggins, J. W., Sep 11 2015, In : Science. 349, 6253, p. 1166-1167 2 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Common variants associated with general and MMR vaccine-related febrile seizures

Feenstra, B., Pasternak, B., Geller, F., Carstensen, L., Wang, T., Huang, F., Eitson, J. L., Hollegaard, M. V., Svanström, H., Vestergaard, M., Hougaard, D. M., Schoggins, J. W., Jan, L. Y., Melbye, M. & Hviid, A., Dec 11 2014, In : Nature genetics. 46, 12, p. 1274-1282 9 p.

Research output: Contribution to journalArticle

67 Scopus citations

Interferon-stimulated genes: Roles in viral pathogenesis

Schoggins, J. W., Jun 2014, In : Current Opinion in Virology. 6, 1, p. 40-46 7 p.

Research output: Contribution to journalReview article

127 Scopus citations

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., Dabelic, R., Manicassamy, B., Aitchison, J. D., Aderem, A., Elliott, R. M., García-Sastre, A., Racaniello, V., Snijder, E. J., Yokoyama, W. M., Diamond, M. S. & 2 others, Virgin, H. W. & Rice, C. M., Jan 1 2014, In : Nature. 505, 7485, p. 691-695 5 p.

Research output: Contribution to journalArticle

403 Scopus citations
2013

Host restriction factor screening: Let the virus do the work

Diamond, M. S. & Schoggins, J. W., Sep 11 2013, In : Cell Host and Microbe. 14, 3, p. 229-231 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

Cheon, H., Holvey-Bates, E. G., Schoggins, J. W., Forster, S., Hertzog, P., Imanaka, N., Rice, C. M., Jackson, M. W., Junk, D. J. & Stark, G. R., Oct 16 2013, In : EMBO Journal. 32, 20, p. 2751-2763 13 p.

Research output: Contribution to journalArticle

121 Scopus citations

Innate immune responses to hepatitis C virus

Schoggins, J. W. & Rice, C. M., Apr 29 2013, Hepatitis C Virus: From Molecular Virology to Antiviral Therapy. p. 219-242 24 p. (Current Topics in Microbiology and Immunology; vol. 369).

Research output: Chapter in Book/Report/Conference proceedingChapter

33 Scopus citations

Lipids in innate antiviral defense

Schoggins, J. W. & Randall, G., Oct 16 2013, In : Cell Host and Microbe. 14, 4, p. 379-385 7 p.

Research output: Contribution to journalReview article

31 Scopus citations

MX2 is an interferon-induced inhibitor of HIV-1 infection

Kane, M., Yadav, S. S., Bitzegeio, J., Kutluay, S. B., Zang, T., Wilson, S. J., Schoggins, J. W., Rice, C. M., Yamashita, M., Hatziioannou, T. & Bieniasz, P. D., Oct 14 2013, In : Nature. 502, 7472, p. 563-566 4 p.

Research output: Contribution to journalArticle

261 Scopus citations

Regulating interferon antiviral activity: A role for epidermal growth factor receptor

Schoggins, J. W., Oct 1 2013, In : Hepatology. 58, 4, p. 1200-1202 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1

Meng, X., Schoggins, J., Rose, L., Cao, J., Ploss, A., Rice, C. M. & Xiang, Y., Apr 1 2012, In : Journal of virology. 86, 8, p. 4538-4547 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro

Schoggins, J. W., Dorner, M., Feulner, M., Imanaka, N., Murphy, M. Y., Ploss, A. & Rice, C. M., Sep 4 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 36, p. 14610-14615 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Inhibition of HIV-1 particle assembly by 2′,3′-cyclic- nucleotide 3′-Phosphodiesterase

Wilson, S. J., Schoggins, J. W., Zang, T., Kutluay, S. B., Jouvenet, N., Alim, M. A., Bitzegeio, J., Rice, C. M. & Bieniasz, P. D., Oct 18 2012, In : Cell Host and Microbe. 12, 4, p. 585-597 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity

Karki, S., Li, M. M. H., Schoggins, J. W., Tian, S., Rice, C. M. & MacDonald, M. R., May 16 2012, In : PloS one. 7, 5, e37398.

Research output: Contribution to journalArticle

41 Scopus citations

Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

Bogunovic, D., Byun, M., Durfee, L. A., Abhyankar, A., Sanal, O., Mansouri, D., Salem, S., Radovanovic, I., Grant, A. V., Adimi, P., Mansouri, N., Okada, S., Bryant, V. L., Kong, X. F., Kreins, A., Velez, M. M., Boisson, B., Khalilzadeh, S., Ozcelik, U., Darazam, I. A. & 12 others, Schoggins, J. W., Rice, C. M., Al-Muhsen, S., Behr, M., Vogt, G., Puel, A., Bustamante, J., Gros, P., Huibregtse, J. M., Abel, L., Boisson-Dupuis, S. & Casanova, J. L., Sep 28 2012, In : Science. 337, 6102, p. 1684-1688 5 p.

Research output: Contribution to journalArticle

256 Scopus citations
2011

A diverse range of gene products are effectors of the type i interferon antiviral response

Schoggins, J. W., Wilson, S. J., Panis, M., Murphy, M. Y., Jones, C. T., Bieniasz, P. & Rice, C. M., Apr 28 2011, In : Nature. 472, 7344, p. 481-485 5 p.

Research output: Contribution to journalArticle

1203 Scopus citations

A genetically humanized mouse model for hepatitis C virus infection

Dorner, M., Horwitz, J. A., Robbins, J. B., Barry, W. T., Feng, Q., Mu, K., Jones, C. T., Schoggins, J. W., Catanese, M. T., Burton, D. R., Law, M., Rice, C. M. & Ploss, A., Jun 8 2011, In : Nature. 474, 7350, p. 208-212 5 p.

Research output: Contribution to journalArticle

277 Scopus citations

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells

Andrus, L., Marukian, S., Jones, C. T., Catanese, M. T., Sheahan, T. P., Schoggins, J. W., Barry, W. T., Dustin, L. B., Trehan, K., Ploss, A., Bhatia, S. N. & Rice, C. M., Dec 1 2011, In : Hepatology. 54, 6, p. 1901-1912 12 p.

Research output: Contribution to journalArticle

68 Scopus citations

Interferon-stimulated genes and their antiviral effector functions

Schoggins, J. W. & Rice, C. M., Dec 2011, In : Current Opinion in Virology. 1, 6, p. 519-525 7 p.

Research output: Contribution to journalReview article

540 Scopus citations
2010

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

Jones, C. T., Catanese, M. T., Law, L. M. J., Khetani, S. R., Syder, A. J., Ploss, A., Oh, T. S., Schoggins, J. W., MacDonald, M. R., Bhatia, S. N. & Rice, C. M., Feb 1 2010, In : Nature biotechnology. 28, 2, p. 167-171 5 p.

Research output: Contribution to journalArticle

181 Scopus citations

Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry

Kohaar, I., Ploss, A., Korol, E., Mu, K., Schoggins, J. W., O'Brien, T. R., Rice, C. M. & Prokunina-Olsson, L., Jul 1 2010, In : Journal of virology. 84, 14, p. 6987-6994 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2009

Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells

Diaz, F., Gravotta, D., Deora, A., Schreiner, R., Schoggins, J., Falck-Pedersen, E. & Rodriguez-Boulan, E., Jul 7 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 27, p. 11143-11148 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber

Schoggins, J. W. & Falck-Pedersen, E., Dec 5 2009, In : Virology. 395, 1, p. 10-20 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
2007

Adenovirus capsid chimeras: fiber terminal exon insertions/gene replacements in the major late transcription unit.

Gall, J., Schoggins, J. & Falck-Pedersen, E., 2007, In : Methods in molecular medicine. 130, p. 107-123 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

Nociari, M., Ocheretina, O., Schoggins, J. W. & Falck-Pedersen, E., Apr 1 2007, In : Journal of virology. 81, 8, p. 4145-4157 13 p.

Research output: Contribution to journalArticle

122 Scopus citations
2006
24 Scopus citations
2005

Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation

Schoggins, J. W., Nociari, M., Philpott, N. & Falck-Pedersen, E., Sep 1 2005, In : Journal of virology. 79, 18, p. 11627-11637 11 p.

Research output: Contribution to journalArticle

30 Scopus citations
2003

Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo

Schoggins, J. W., Gall, J. G. D. & Falck-Pedersen, E., Jan 1 2003, In : Journal of virology. 77, 2, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

49 Scopus citations