Microbiology - Schoggins Lab - Administration

Research Output 1999 2019

2019

A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB

Liu, Z., Mar, K. B., Hanners, N. W., Perelman, S. S., Kanchwala, M., Xing, C., Schoggins, J. W. & Alto, N. M., Jan 1 2019, In : Nature.

Research output: Contribution to journalLetter

Transcription Factors
Inflammation
Organogenesis
Homeobox Genes
Immune System Diseases
3 Citations (Scopus)

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape

Hubel, P., Urban, C., Bergant, V., Schneider, W. M., Knauer, B., Stukalov, A., Scaturro, P., Mann, A., Brunotte, L., Hoffmann, H. H., Schoggins, J. W., Schwemmle, M., Mann, M., Rice, C. M. & Pichlmair, A., Jan 1 2019, In : Nature Immunology.

Research output: Contribution to journalArticle

Protein Interaction Maps
Interferons
Immune System
Gene Regulatory Networks
Genes

Comparative analysis of viral entry for Asian and African lineages of Zika virus

Rinkenberger, N. & Schoggins, J. W., Jul 1 2019, In : Virology. 533, p. 59-67 9 p.

Research output: Contribution to journalArticle

Virus Internalization
Zika Virus
Clathrin
Endosomes
Endocytosis

Interferon-Stimulated Genes: What Do They All Do?

Schoggins, J. W., Sep 29 2019, In : Annual Review of Virology. 6, p. 567-584 18 p.

Research output: Contribution to journalArticle

Interferons
Genes
Antiviral Agents
Adaptive Immunity
Human Genome
12 Citations (Scopus)

Shared and Distinct Functions of Type I and Type III Interferons

Lazear, H. M., Schoggins, J. W. & Diamond, M. S., Apr 16 2019, In : Immunity. 50, 4, p. 907-923 17 p.

Research output: Contribution to journalReview article

Interferon Type I
Interferons
Virus Activation
Virus Diseases
Infection Control
2018
11 Citations (Scopus)

A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication

Richardson, R. B., Ohlson, M. B., Eitson, J. L., Kumar, A., McDougal, M. B., Boys, I. N., Mar, K. B., De La Cruz-Rivera, P. C., Douglas, C., Konopka, G., Xing, C. & Schoggins, J. W., Nov 1 2018, In : Nature Microbiology. 3, 11, p. 1214-1223 10 p.

Research output: Contribution to journalLetter

Clustered Regularly Interspaced Short Palindromic Repeats
Flavivirus
Endoplasmic Reticulum
Interferons
Proteins
3 Citations (Scopus)

Genetic variation at IFNL4 influences extrahepatic interferon-stimulated gene expression in chronic HCV patients

Rosenberg, B. R., Freije, C. A., Imanaka, N., Chen, S. T., Eitson, J. L., Caron, R., Uhl, S. A., Zeremski, M., Talal, A., Jacobson, I. M., Rice, C. M. & Schoggins, J. W., Feb 15 2018, In : Journal of Infectious Diseases. 217, 4, p. 650-655 6 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Hepacivirus
Interferons
Virus Diseases
Gene Expression
4 Citations (Scopus)

LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step

Mar, K. B., Rinkenberger, N. R., Boys, I. N., Eitson, J. L., McDougal, M. B., Richardson, R. B. & Schoggins, J. W., Dec 1 2018, In : Nature Communications. 9, 1, 3603.

Research output: Contribution to journalArticle

interferon
viruses
infectious diseases
Virus Diseases
Viruses
7 Citations (Scopus)

Mucolipin-2 cation channel increases trafficking efficiency of endocytosed viruses

Rinkenberger, N. & Schoggins, J. W., Jan 1 2018, In : mBio. 9, 1, e02314-17.

Research output: Contribution to journalArticle

Endocytosis
Cations
Viruses
Life Cycle Stages
Yellow fever virus
8 Citations (Scopus)

Recent advances in antiviral interferon-stimulated gene biology

Schoggins, J. W., Jan 1 2018, In : F1000Research. 7, 309.

Research output: Contribution to journalReview article

Interferons
Antiviral Agents
Genes
Pathogens
Screening
8 Citations (Scopus)

The IFN response in bats displays distinctive ifn-stimulated gene expression kinetics with atypical RNASEL induction

De La Cruz-Rivera, P. C., Kanchwala, M., Liang, H., Kumar, A., Wang, L. F., Xing, C. & Schoggins, J. W., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 209-217 9 p.

Research output: Contribution to journalArticle

Gene Expression
Virus Diseases
Viruses
Antiviral Agents
Endoribonucleases
2017
3 Citations (Scopus)

The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry

Lipovsky, A., Erden, A., Kanaya, E., Zhang, W., Crite, M., Bradfield, C., MacMicking, J., DiMaio, D., Schoggins, J. W. & Iwasaki, A., Nov 1 2017, In : Journal of General Virology. 98, 11, p. 2821-2836 16 p., 000954.

Research output: Contribution to journalArticle

Papillomaviridae
Virus Internalization
Proteins
Viruses
trans-Golgi Network
2016
5 Citations (Scopus)

Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection

Perelman, S. S., Abrams, M. E., Eitson, J. L., Chen, D., Jimenez, A., Mettlen, M., Schoggins, J. W. & Alto, N. M., Dec 21 2016, In : PLoS Pathogens. 12, 12, e1006102.

Research output: Contribution to journalArticle

Listeriosis
Listeria monocytogenes
Interferons
Genes
Interferon Type I
45 Citations (Scopus)

Identification of Interferon-Stimulated Genes with Antiretroviral Activity

Kane, M., Zang, T. M., Rihn, S. J., Zhang, F., Kueck, T., Alim, M., Schoggins, J., Rice, C. M., Wilson, S. J. & Bieniasz, P. D., Sep 14 2016, In : Cell Host and Microbe. 20, 3, p. 392-405 14 p.

Research output: Contribution to journalArticle

Interferons
Genes
Indoleamine-Pyrrole 2,3,-Dioxygenase
Macaca
Retroviridae
4 Citations (Scopus)

NLRX1 Helps HIV Avoid a STING Operation

Mar, K. B. & Schoggins, J. W., Apr 13 2016, In : Cell Host and Microbe. 19, 4, p. 430-431 2 p.

Research output: Contribution to journalArticle

HIV-1
HIV
Immune Evasion
Innate Immunity
Viruses
63 Citations (Scopus)

Western Zika Virus in Human Fetal Neural Progenitors Persists Long Term with Partial Cytopathic and Limited Immunogenic Effects

Hanners, N. W., Eitson, J. L., Usui, N., Richardson, R. B., Wexler, E. M., Konopka, G. & Schoggins, J. W., Jun 14 2016, In : Cell Reports. 15, 11, p. 2315-2322 8 p.

Research output: Contribution to journalArticle

Viruses
Pathology
Flavivirus
Microcephaly
Virus Replication
2015

A phospholipase linkAGE to SARS susceptibility

Schoggins, J. W., 2015, In : Journal of Experimental Medicine. 212, 11, p. 1755 1 p.

Research output: Contribution to journalArticle

Group II Phospholipases A2
Severe Acute Respiratory Syndrome
Phospholipases
Disease Susceptibility
2 Citations (Scopus)

A Sense of Self: RIG-I's Tolerance to Host RNA

Schoggins, J. W., Jul 21 2015, In : Immunity. 43, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

RNA
Viral RNA
Histidine
Immunity
2 Citations (Scopus)

Erratum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity (Nature (2014) 505 (691-695) (DOI:10.1038/nature12862))

Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., Dabelic, R., Manicassamy, B., Aitchison, J. D., Aderem, A., Elliott, R. M., García-Sastre, A., Racaniello, V., Snijder, E. J., Yokoyama, W. M., Diamond, M. S. & 2 others, Virgin, H. W. & Rice, C. M., Sep 3 2015, In : Nature. 525, 7567, p. 144 1 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Erratum: A diverse range of gene products are effectors of the type I interferon antiviral response (Nature (2015) 472 (481-485) (DOI:10.1038/nature09907))

Schoggins, J. W., Wilson, S. J., Panis, M., Murphy, M. Y., Jones, C. T., Bieniasz, P. & Rice, C. M., Sep 3 2015, In : Nature. 525, 7567, p. 144 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Viruses carry antiviral cargo

Schoggins, J. W., Sep 11 2015, In : Science. 349, 6253, p. 1166-1167 2 p.

Research output: Contribution to journalArticle

cells and cell components
Muromegalovirus
arms race
Vaccinia
Herpesviridae Infections
2014
56 Citations (Scopus)

Common variants associated with general and MMR vaccine-related febrile seizures

Feenstra, B., Pasternak, B., Geller, F., Carstensen, L., Wang, T., Huang, F., Eitson, J. L., Hollegaard, M. V., Svanström, H., Vestergaard, M., Hougaard, D. M., Schoggins, J. W., Jan, L. Y., Melbye, M. & Hviid, A., Dec 11 2014, In : Nature Genetics. 46, 12, p. 1274-1282 9 p.

Research output: Contribution to journalArticle

Measles-Mumps-Rubella Vaccine
Febrile Seizures
Mumps
Rubella
Measles
111 Citations (Scopus)

Interferon-stimulated genes: Roles in viral pathogenesis

Schoggins, J. W., 2014, In : Current Opinion in Virology. 6, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

Interferons
Virus Diseases
Genes
Viral Genes
Knockout Mice
366 Citations (Scopus)

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., Dabelic, R., Manicassamy, B., Aitchison, J. D., Aderem, A., Elliott, R. M., García-Sastre, A., Racaniello, V., Snijder, E. J., Yokoyama, W. M., Diamond, M. S. & 2 others, Virgin, H. W. & Rice, C. M., 2014, In : Nature. 505, 7485, p. 691-695 5 p.

Research output: Contribution to journalArticle

Innate Immunity
Interferons
RNA Viruses
Antiviral Agents
Genes
2013
2 Citations (Scopus)

Host restriction factor screening: Let the virus do the work

Diamond, M. S. & Schoggins, J. W., Sep 11 2013, In : Cell Host and Microbe. 14, 3, p. 229-231 3 p.

Research output: Contribution to journalArticle

RNA Viruses
Virus Diseases
Small Interfering RNA
Viruses
Genes
103 Citations (Scopus)

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

Cheon, H., Holvey-Bates, E. G., Schoggins, J. W., Forster, S., Hertzog, P., Imanaka, N., Rice, C. M., Jackson, M. W., Junk, D. J. & Stark, G. R., Oct 16 2013, In : EMBO Journal. 32, 20, p. 2751-2763 13 p.

Research output: Contribution to journalArticle

Viruses
Interferons
DNA Damage
DNA
Tyrosine
32 Citations (Scopus)

Innate immune responses to hepatitis C virus

Schoggins, J. W. & Rice, C. M., 2013, Current Topics in Microbiology and Immunology. Vol. 369. p. 219-242 24 p. (Current Topics in Microbiology and Immunology; vol. 369).

Research output: Chapter in Book/Report/Conference proceedingChapter

Innate Immunity
Hepacivirus
Virus Diseases
Cell Culture Techniques
Virus Replication
27 Citations (Scopus)

Lipids in innate antiviral defense

Schoggins, J. W. & Randall, G., Oct 16 2013, In : Cell Host and Microbe. 14, 4, p. 379-385 7 p.

Research output: Contribution to journalArticle

Antiviral Agents
Viruses
Lipids
Membranes
Virion
240 Citations (Scopus)

MX2 is an interferon-induced inhibitor of HIV-1 infection

Kane, M., Yadav, S. S., Bitzegeio, J., Kutluay, S. B., Zang, T., Wilson, S. J., Schoggins, J. W., Rice, C. M., Yamashita, M., Hatziioannou, T. & Bieniasz, P. D., 2013, In : Nature. 502, 7472, p. 563-566 4 p.

Research output: Contribution to journalArticle

Orthomyxoviridae
Interferons
HIV Infections
HIV-1
Interferon Type I
2 Citations (Scopus)

Regulating interferon antiviral activity: A role for epidermal growth factor receptor

Schoggins, J. W., Oct 2013, In : Hepatology. 58, 4, p. 1200-1202 3 p.

Research output: Contribution to journalArticle

Hepatitis C
Epidermal Growth Factor Receptor
Interferon-alpha
Hepacivirus
Interferons
2012
24 Citations (Scopus)

C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1

Meng, X., Schoggins, J., Rose, L., Cao, J., Ploss, A., Rice, C. M. & Xiang, Y., Apr 2012, In : Journal of Virology. 86, 8, p. 4538-4547 10 p.

Research output: Contribution to journalArticle

Poxviridae
Interferon Regulatory Factor-1
Interferon Type I
Vaccinia virus
Host Specificity
91 Citations (Scopus)

Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro

Schoggins, J. W., Dorner, M., Feulner, M., Imanaka, N., Murphy, M. Y., Ploss, A. & Rice, C. M., Sep 4 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 36, p. 14610-14615 6 p.

Research output: Contribution to journalArticle

Interferon Receptors
Dengue Virus
Interferons
Antiviral Agents
Viruses
33 Citations (Scopus)

Inhibition of HIV-1 particle assembly by 2′,3′-cyclic- nucleotide 3′-Phosphodiesterase

Wilson, S. J., Schoggins, J. W., Zang, T., Kutluay, S. B., Jouvenet, N., Alim, M. A., Bitzegeio, J., Rice, C. M. & Bieniasz, P. D., Oct 18 2012, In : Cell Host and Microbe. 12, 4, p. 585-597 13 p.

Research output: Contribution to journalArticle

Cyclic Nucleotides
Phosphoric Diester Hydrolases
HIV-1
Antiviral Agents
Interferons
39 Citations (Scopus)

Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity

Karki, S., Li, M. M. H., Schoggins, J. W., Tian, S., Rice, C. M. & MacDonald, M. R., May 16 2012, In : PLoS One. 7, 5, e37398.

Research output: Contribution to journalArticle

antiviral proteins
Alphavirus
zinc finger motif
Zinc Fingers
interferons
231 Citations (Scopus)

Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

Bogunovic, D., Byun, M., Durfee, L. A., Abhyankar, A., Sanal, O., Mansouri, D., Salem, S., Radovanovic, I., Grant, A. V., Adimi, P., Mansouri, N., Okada, S., Bryant, V. L., Kong, X. F., Kreins, A., Velez, M. M., Boisson, B., Khalilzadeh, S., Ozcelik, U., Darazam, I. A. & 12 others, Schoggins, J. W., Rice, C. M., Al-Muhsen, S., Behr, M., Vogt, G., Puel, A., Bustamante, J., Gros, P., Huibregtse, J. M., Abel, L., Boisson-Dupuis, S. & Casanova, J. L., Sep 28 2012, In : Science. 337, 6102, p. 1684-1688 5 p.

Research output: Contribution to journalArticle

Interferons
Immunity
Virus Diseases
Antiviral Agents
Ubiquitins
2011
1119 Citations (Scopus)

A diverse range of gene products are effectors of the type i interferon antiviral response

Schoggins, J. W., Wilson, S. J., Panis, M., Murphy, M. Y., Jones, C. T., Bieniasz, P. & Rice, C. M., Apr 28 2011, In : Nature. 472, 7344, p. 481-485 5 p.

Research output: Contribution to journalArticle

Interferons
Antiviral Agents
Interferon Type I
Genes
Venezuelan Equine Encephalitis Viruses
272 Citations (Scopus)

A genetically humanized mouse model for hepatitis C virus infection

Dorner, M., Horwitz, J. A., Robbins, J. B., Barry, W. T., Feng, Q., Mu, K., Jones, C. T., Schoggins, J. W., Catanese, M. T., Burton, D. R., Law, M., Rice, C. M. & Ploss, A., Jun 8 2011, In : Nature. 474, 7350, p. 208-212 5 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Virus Internalization
CD36 Antigens
Occludin
66 Citations (Scopus)

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells

Andrus, L., Marukian, S., Jones, C. T., Catanese, M. T., Sheahan, T. P., Schoggins, J. W., Barry, W. T., Dustin, L. B., Trehan, K., Ploss, A., Bhatia, S. N. & Rice, C. M., Dec 2011, In : Hepatology. 54, 6, p. 1901-1912 12 p.

Research output: Contribution to journalArticle

Hepacivirus
Liver
Virus Diseases
Interferons
Paramyxovirus V protein
481 Citations (Scopus)

Interferon-stimulated genes and their antiviral effector functions

Schoggins, J. W. & Rice, C. M., Dec 2011, In : Current Opinion in Virology. 1, 6, p. 519-525 7 p.

Research output: Contribution to journalArticle

Interferons
Antiviral Agents
Genes
Viruses
Interferon Type I
2010
175 Citations (Scopus)

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

Jones, C. T., Catanese, M. T., Law, L. M. J., Khetani, S. R., Syder, A. J., Ploss, A., Oh, T. S., Schoggins, J. W., MacDonald, M. R., Bhatia, S. N. & Rice, C. M., Feb 2010, In : Nature Biotechnology. 28, 2, p. 167-171 5 p.

Research output: Contribution to journalArticle

Virus Diseases
Viruses
Hepacivirus
Imaging techniques
Chronic Hepatitis
27 Citations (Scopus)

Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry

Kohaar, I., Ploss, A., Korol, E., Mu, K., Schoggins, J. W., O'Brien, T. R., Rice, C. M. & Prokunina-Olsson, L., Jul 2010, In : Journal of Virology. 84, 14, p. 6987-6994 8 p.

Research output: Contribution to journalArticle

Occludin
Virus Internalization
Hepatitis C virus
Hepacivirus
Genes
2009
50 Citations (Scopus)

Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells

Diaz, F., Gravotta, D., Deora, A., Schreiner, R., Schoggins, J., Falck-Pedersen, E. & Rodriguez-Boulan, E., Jul 7 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 27, p. 11143-11148 6 p.

Research output: Contribution to journalArticle

Coxsackie and Adenovirus Receptor-Like Membrane Protein
Vesicular Transport Adaptor Proteins
Adenoviridae
Epithelial Cells
Madin Darby Canine Kidney Cells
1 Citation (Scopus)

Serotype 5 Adenovirus fiber (F7F41S) chimeric vectors incur packaging deficiencies when targeting peptides are inserted into Ad41 short fiber

Schoggins, J. W. & Falck-Pedersen, E., Dec 5 2009, In : Virology. 395, 1, p. 10-20 11 p.

Research output: Contribution to journalArticle

Product Packaging
Adenoviridae
Virion
Capsid
Peptides
2007
3 Citations (Scopus)

Adenovirus capsid chimeras: fiber terminal exon insertions/gene replacements in the major late transcription unit.

Gall, J., Schoggins, J. & Falck-Pedersen, E., 2007, In : Methods in molecular medicine. 130, p. 107-123 17 p.

Research output: Contribution to journalArticle

Insertional Mutagenesis
Capsid
Capsid Proteins
Adenoviridae
Adenoviridae Infections
120 Citations (Scopus)

Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

Nociari, M., Ocheretina, O., Schoggins, J. W. & Falck-Pedersen, E., Apr 2007, In : Journal of Virology. 81, 8, p. 4145-4157 13 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Adenoviridae Infections
Toll-Like Receptors
Adenoviridae
Antiviral Agents
2006
24 Citations (Scopus)
capsid
Capsid
Capsid Proteins
Adenoviridae
Humoral Immunity
2005
30 Citations (Scopus)

Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation

Schoggins, J. W., Nociari, M., Philpott, N. & Falck-Pedersen, E., Sep 2005, In : Journal of Virology. 79, 18, p. 11627-11637 11 p.

Research output: Contribution to journalArticle

Coxsackie and Adenovirus Receptor-Like Membrane Protein
Adenoviridae
receptors
Chemokines
Liver
2003
49 Citations (Scopus)

Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo

Schoggins, J. W., Gall, J. G. D. & Falck-Pedersen, E., Jan 2003, In : Journal of Virology. 77, 2, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

chimerism
Adenoviridae
Enterovirus
receptors
Adenoviridae Infections
2000
39 Citations (Scopus)

Coordinate expression of secretory phospholipase A2 and cyclooxygenase- 2 in activated human keratinocytes

Rys-Sikora, K. E., Konger, R. L., Schoggins, J. W., Malaviya, R. & Pentland, A. P., 2000, In : American Journal of Physiology - Cell Physiology. 278, 4 47-4

Research output: Contribution to journalArticle

Secretory Phospholipase A2
Cyclooxygenase 2
Keratinocytes
Dinoprostone
Autacoids
1999
283 Citations (Scopus)

Reduction of UV-induced skin tumors in hairless mice by selective COX-2 inhibition

Pentland, A. P., Schoggins, J. W., Scott, G. A., Khan, K. N. M. & Han, R., 1999, In : Carcinogenesis. 20, 10, p. 1939-1944 6 p.

Research output: Contribution to journalArticle

Hairless Mouse
Celecoxib
Skin
Neoplasms
Cyclooxygenase 2 Inhibitors