Research Output 1968 2019

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2019

A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity

Lopez, V. A., Park, B. C., Nowak, D., Sreelatha, A., Zembek, P., Fernandez, J., Servage, K. A., Gradowski, M., Hennig, J., Tomchick, D. R., Pawłowski, K., Krzymowska, M. & Tagliabracci, V. S., Sep 19 2019, In : Cell. 179, 1, p. 205-218.e21

Research output: Contribution to journalArticle

Protein Kinases
Immunity
Phosphorylation
Pathogens
Plant Immunity
2 Citations (Scopus)

Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

Hu, Z., Qu, G., Yu, X., Jiang, H., Teng, X. L., Ding, L., Hu, Q., Guo, X., Zhou, Y., Wang, F., Li, H. B., Chen, L., Jiang, J., Su, B., Liu, J. & Zou, Q., Aug 6 2019, In : Cell Metabolism. 30, 2, p. 290-302.e5

Research output: Contribution to journalArticle

acylglycerol kinase
T-Lymphocytes
Glycolysis
PTEN Phosphohydrolase
Sirolimus
4 Citations (Scopus)

Astrocyte-Specific Deletion of Sox2 Promotes Functional Recovery After Traumatic Brain Injury

Chen, C., Zhong, X., Smith, D. K., Tai, W., Yang, J., Zou, Y., Wang, L. L., Sun, J., Qin, S. & Zhang, C-L., Jan 1 2019, In : Cerebral cortex (New York, N.Y. : 1991). 29, 1, p. 54-69 16 p.

Research output: Contribution to journalArticle

Astrocytes
Wounds and Injuries
Neuroglia
SOXB1 Transcription Factors
Chromatin Immunoprecipitation
4 Citations (Scopus)

Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases

Black, M. H., Osinski, A., Gradowski, M., Servage, K. A., Pawłowski, K., Tomchick, D. R. & Tagliabracci, V. S., May 24 2019, In : Science (New York, N.Y.). 364, 6442, p. 787-792 6 p.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Protein Kinases
Legionella
Calmodulin
2 Citations (Scopus)

Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers

Hashimoto, H., Wang, Z., Garry, G. A., Malladi, V. S., Botten, G. A., Ye, W., Zhou, H., Osterwalder, M., Dickel, D. E., Visel, A., Liu, N., Bassel-Duby, R. S. & Olson, E. N., Jul 3 2019, In : Cell Stem Cell. 25, 1, p. 69-86.e5

Research output: Contribution to journalArticle

Transcription Factors
Genome
Cardiac Myocytes
Gene Regulatory Networks
Fibroblasts
1 Citation (Scopus)

Cardio-omentopexy Reduces Cardiac Fibrosis and Heart Failure After Experimental Pressure Overload

Wang, J., Zhang, Q. J., Pirolli, T. J., Liu, Z-P., Powell, L. S., Thorp, E. B., Jessen, M. E. & Forbess, J. M., Jan 1 2019, In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Left Ventricular Hypertrophy
Fibrosis
Heart Failure
Pressure
Thoracotomy
1 Citation (Scopus)

Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution

Hosein, A. N., Huang, H., Wang, Z., Parmar, K., Du, W., Huang, J., Maitra, A., Olson, E. N., Verma, U. & Brekken, R. A., Jul 23 2019, In : JCI Insight. 4, 16, e129212.

Research output: Contribution to journalArticle

Open Access
Adenocarcinoma
Fibroblasts
Neoplasms
Stromal Cells
Population
2 Citations (Scopus)

cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model

Xiao, N., Wei, J., Xu, S., Du, H., Huang, M., Zhang, S., Ye, W., Sun, L. & Chen, Q., Jun 1 2019, In : Journal of Autoimmunity. 100, p. 84-94 11 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Genes
Autoimmune Diseases
Exodeoxyribonucleases
Inflammation

Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

Livingston, M. J., Wang, J., Zhou, J., Wu, G., Ganley, I. G., Hill, J. A., Yin, X. M. & Dong, Z., Jan 1 2019, In : Autophagy.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Degradation
Ischemic Preconditioning
Mitochondria
Kidney
Autophagy
7 Citations (Scopus)

CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

Min, Y. L., Li, H., Rodriguez-Caycedo, C., Mireault, A. A., Huang, J., Shelton, J. M., McAnally, J. R., Amoasii, L., Mammen, P. P., Bassel-Duby, R. S. & Olson, E. N., Jan 1 2019, In : Science Advances. 5, 3, eaav4324.

Research output: Contribution to journalArticle

Open Access
deletion
mutations
genes
mice
editing
2 Citations (Scopus)

Defective DNA Polymerase α-Primase Leads to X-Linked Intellectual Disability Associated with Severe Growth Retardation, Microcephaly, and Hypogonadism

Van Esch, H., Colnaghi, R., Freson, K., Starokadomskyy, P., Zankl, A., Backx, L., Abramowicz, I., Outwin, E., Rohena, L., Faulkner, C., Leong, G. M., Newbury-Ecob, R. A., Challis, R. C., Õunap, K., Jaeken, J., Seuntjens, E., Devriendt, K., Burstein, E., Low, K. J. & O'Driscoll, M., May 2 2019, In : American Journal of Human Genetics. 104, 5, p. 957-967 11 p.

Research output: Contribution to journalArticle

DNA Primase
Microcephaly
Hypogonadism
DNA-Directed DNA Polymerase
Intellectual Disability

Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group

Fonseca, A., Xia, C., Lorenzo, A. J., Krailo, M., Olson, T. A., Pashankar, F., Malogolowkin, M. H., Amatruda, J. F., Billmire, D. F., Rodriguez-Galindo, C., Frazier, A. L. & Shaikh, F., Feb 10 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 5, p. 396-402 7 p.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
Tumor Biomarkers
Recurrence
Ionizing Radiation
Pathology
1 Citation (Scopus)

Direct Detection of Tissue-Resident Bacteria and Chronic Inflammation in the Bladder Wall of Postmenopausal Women with Recurrent Urinary Tract Infection

De Nisco, N. J., Neugent, M., Mull, J. A., Chen, L., Kuprasertkul, A., de Souza Santos, M., Palmer, K. L., Zimmern, P. E. & Orth, K. A., Jan 1 2019, In : Journal of Molecular Biology.

Research output: Contribution to journalArticle

Urinary Tract Infections
Urinary Bladder
Urothelium
Inflammation
Bacteria
4 Citations (Scopus)

Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration

Abdullah, C. S., Alam, S., Aishwarya, R., Miriyala, S., Bhuiyan, M. A. N., Panchatcharam, M., Pattillo, C. B., Orr, A. W., Sadoshima, J., Hill, J. A. & Bhuiyan, M. S., Dec 1 2019, In : Scientific Reports. 9, 1, 2002.

Research output: Contribution to journalArticle

Cardiomyopathies
Doxorubicin
Respiration
Mitochondrial Dynamics
Autophagy

Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer

Zhu, W., Miyata, N., Winter, M. G., Arenales, A., Hughes, E. R., Spiga, L., Kim, J., Sifuentes-Dominguez, L., Starokadomskyy, P., Gopal, P., Byndloss, M. X., Santos, R. L., Burstein, E. & Winter, S. E., Oct 7 2019, In : The Journal of experimental medicine. 216, 10, p. 2378-2393 16 p.

Research output: Contribution to journalArticle

Open Access
Azoxymethane
Colitis
Colorectal Neoplasms
Carcinogenesis
Enterobacteriaceae

Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling

Singla, A., Fedoseienko, A., Giridharan, S. S. P., Overlee, B. L., Lopez, A., Jia, D., Song, J., Huff-Hardy, K., Weisman, L., Burstein, E. & Billadeau, D. D., Sep 19 2019, In : Nature communications. 10, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Recycling
recycling
phosphates
Membrane Proteins
membranes
2 Citations (Scopus)

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis

Villalobos, E., Criollo, A., Schiattarella, G. G., Altamirano, F., French, K. M., May, H. I., Jiang, N., Nguyen, N. U. N., Romero, D., Roa, J. C., García, L., Diaz-Araya, G., Morselli, E., Ferdous, A., Conway, S. J., Sadek, H. A., Gillette, T. G., Lavandero, S. & Hill, J. A., May 14 2019, In : Circulation. 139, 20, p. 2342-2357 16 p.

Research output: Contribution to journalArticle

Cilia
Fibrosis
Fibroblasts
Myofibroblasts
Extracellular Matrix Proteins

Genetics of testicular germ cell tumors

Singla, N., Lafin, J. T., Ghandour, R. A., Kaffenberger, S., Amatruda, J. F. & Bagrodia, A., Jul 1 2019, In : Current opinion in urology. 29, 4, p. 344-349 6 p.

Research output: Contribution to journalArticle

Testicular Germ Cell Tumor
Seminoma
Mutation
Penetrance
Loss of Heterozygosity

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

Jewell, J. L., Fu, V., Hong, A. W., Yu, F. X., Meng, D., Melick, C. H., Wang, H., Lam, W. L. M., Yuan, H. X., Taylor, S. S. & Guan, K. L., May 21 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Raptors
Phosphorylation
G-Protein-Coupled Receptors
Cyclic AMP-Dependent Protein Kinases
mechanistic target of rapamycin complex 1

Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming

Fernandez-Perez, A., Sathe, A. A., Bhakta, M., Leggett, K., Xing, C. & Munshi, N. V., May 21 2019, In : Cell Reports. 27, 8, p. 2354-2369.e7

Research output: Contribution to journalArticle

Open Access
Pacemakers
Muscle Cells
Chromatin
Desmosomes
Sarcomeres
3 Citations (Scopus)

High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice

Peri-Okonny, P., Baskin, K. K., Iwamoto, G. A., Mitchell, J. H., Smith, S. A., Kim, H. K., Szweda, L. I., Bassel-Duby, R. S., Fujikawa, T., Castorena, C. M., Richardson, J. A., Shelton, J. M., Ayers, C., Berry, J. D., Malladi, V. S., Hu, M. C., Moe, O. W., Scherer, P. E. & Vongpatanasin, W., Mar 12 2019, In : Circulation. 139, 11, p. 1422-1434 13 p.

Research output: Contribution to journalArticle

Fatty Acids
Phosphates
Diet
Skeletal Muscle Fibers
Serum

High-resolution cryo-EM structures of the E. Coli hemolysin ClyA oligomers

Peng, W., de Souza Santos, M., Li, Y., Tomchick, D. R. & Orth, K. A., May 1 2019, In : PloS one. 14, 5, e0213423.

Research output: Contribution to journalArticle

Open Access
hemolysins
Protein Subunits
protein subunits
Oligomers
Porins

Hippo signaling is intrinsically regulated during cell cycle progression by APC/C Cdh1

Kim, W., Cho, Y. S., Wang, X., Park, O., Ma, X., Kim, H., Gan, W., Jho, E. H., Cha, B., Jeung, Y. J., Zhang, L., Gao, B., Wei, W., Jiang, J., Chung, K. S. & Yang, Y., May 7 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9423-9432 10 p.

Research output: Contribution to journalArticle

Anaphase-Promoting Complex-Cyclosome
Cell Cycle
Neoplasms
Warts
Phosphotransferases
2 Citations (Scopus)

Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation

Stefanius, K., Servage, K., de Souza Santos, M., Gray, H. F., Toombs, J. E., Chimalapati, S., Kim, M. S., Malladi, V. S., Brekken, R. A. & Orth, K. A., May 28 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Exosomes
Pancreatic Neoplasms
Cells
Tumors
Neoplasms

Hydralazine targets cAMP-dependent protein kinase leading to sirtuin1/5 activation and lifespan extension in C. elegans

Dehghan, E., Goodarzi, M., Saremi, B., Lin, R. & Mirzaei, H., Dec 1 2019, In : Nature communications. 10, 1, 4905.

Research output: Contribution to journalArticle

Open Access
Hydralazine
Cyclic AMP-Dependent Protein Kinases
Chemical activation
activation
proteins

Identification of testicular cancer driver genes by a cross-species comparative oncology approach

Sanchez, A., Xu, L., Pierce, J. L., Lafin, J. T., Abe, D., Bagrodia, A., Frazier, A. L. & Amatruda, J. F., Jan 1 2019, In : Andrology.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
Neoplasm Genes
Testicular Neoplasms
Zebrafish
Germ Cells

LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation

Braitsch, C. M., Azizoglu, D. B., Htike, Y., Barlow, H. R., Schnell, U., Chaney, C. P., Carroll, T. J., Stanger, B. Z. & Cleaver, O., Jul 1 2019, In : PLoS biology. 17, 7, e3000382.

Research output: Contribution to journalArticle

Open Access
Cell signaling
Epithelial-Mesenchymal Transition
pancreas
cell differentiation
Tumors

Lung cancer progression using fast switching multiple ion beam radiation and countermeasure prevention

Luitel, K., Kim, S. B., Barron, S., Richardson, J. A. & Shay, J. W., Jan 1 2019, (Accepted/In press) In : Life Sciences in Space Research.

Research output: Contribution to journalArticle

countermeasures
lung neoplasms
progressions
lungs
mice

Mean platelet volume predicts survival in patients with hepatocellular carcinoma and type 2 diabetes

Yin, J. B., Niu, Y., Qian, L. Y., Zhang, X., Liu, Z-P. & Wang, R. T., May 1 2019, In : Diabetes Research and Clinical Practice. 151, p. 120-127 8 p.

Research output: Contribution to journalArticle

Mean Platelet Volume
Type 2 Diabetes Mellitus
Hepatocellular Carcinoma
Survival
Platelet Activation

Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

Wang, Z., Cui, M., Shah, A. M., Ye, W., Tan, W., Min, Y. L., Botten, G. A., Shelton, J. M., Liu, N., Bassel-Duby, R. S. & Olson, E. N., Sep 10 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 37, p. 18455-18465 11 p.

Research output: Contribution to journalArticle

Open Access
Histone Code
Transcriptome
Regeneration
Genes
RNA-Binding Proteins

Medical Misinformation: Vet the Message!

Hill, J. A., Feb 1 2019, In : European heart journal. Acute cardiovascular care. 8, 1, p. 5-7 3 p.

Research output: Contribution to journalArticle

Open Access
Social Media
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Information Dissemination
Vaccination
Cardiovascular Diseases

MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary

Du, Q., Hoover, A. R., Dozmorov, I., Raj, P., Khan, S., Molina, E., Chang, T-C., De La Morena, M. T., Cleaver, O., Mendell, J. T. & Van Oers, N., May 20 2019, In : Developmental Cell. 49, 4, p. 618-631.e5

Research output: Contribution to journalArticle

Long Noncoding RNA
Prolactin
Growth Hormone
MicroRNAs
Genes

MiR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19

Acharya, A., Berry, D. C., Zhang, H., Jiang, Y., Jones, B. T., Hammer, R. E., Graff, J. M. & Mendell, J. T., Oct 1 2019, In : Genes and Development. 33, 19-20, p. 1367-1380 14 p.

Research output: Contribution to journalArticle

Open Access
Adipogenesis
White Adipose Tissue
MicroRNAs
Adipocytes
Obesity
2 Citations (Scopus)

Modulation of mutant krasG12D-driven lung tumorigenesis in vivo by gain or loss of PCDH7 function

Zhou, X., Padanad, M. S., Evers, B. M., Smith, B., Novaresi, N., Suresh, S., Richardson, J. A., Stein, E., Zhu, J., Hammer, R. E. & O'Donnell-Mendell, K. A., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 594-603 10 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Carcinogenesis
Clustered Regularly Interspaced Short Palindromic Repeats
Lung
Neoplasms

Molecular determinants of WNT9b responsiveness in nephron progenitor cells

Dickinson, K. K., Hammond, L. C., Karner, C. M., Hastie, N. D., Carroll, T. J. & Goodyer, P., Apr 1 2019, In : PloS one. 14, 4, e0215139.

Research output: Contribution to journalArticle

Open Access
nephrons
Nephrons
stem cells
Mesoderm
Stem Cells

Mosaic Tetrasomy 9p Associated With Inflammatory Bowel Disease

Sifuentes-Dominguez, L., Starokadomskyy, P., Welch, J., Gurram, B., Park, J. Y., Koduru, P. & Burstein, E., Oct 28 2019, In : Journal of Crohn's & colitis. 13, 11, p. 1474-1478 5 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Interferon Type I
Interferons
Inflammation
Multigene Family
MEF2 Transcription Factors
Suprachiasmatic Nucleus
Sleep
Brain
Proteins

Newly Discovered Micropeptide Regulators of SERCA Form Oligomers but Bind to the Pump as Monomers

Singh, D. R., Dalton, M. P., Cho, E. E., Pribadi, M. P., Zak, T. J., Šeflová, J., Makarewich, C. A., Olson, E. N. & Robia, S. L., Jan 1 2019, (Accepted/In press) In : Journal of Molecular Biology.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Open Reading Frames
Protein Subunits
Immunoprecipitation
Calcium
8 Citations (Scopus)

Nitrosative stress drives heart failure with preserved ejection fraction

Schiattarella, G. G., Altamirano, F., Tong, D., French, K. M., Villalobos, E., Kim, S. Y., Luo, X., Jiang, N., May, H. I., Wang, Z., Hill, T. M., Mammen, P. P., Huang, J., Lee, D. I., Hahn, V. S., Sharma, K., Kass, D. A., Lavandero, S., Gillette, T. G. & Hill, J. A., Apr 18 2019, In : Nature. 568, 7752, p. 351-356 6 p.

Research output: Contribution to journalArticle

Heart Failure
Nitric Oxide Synthase Type II
Cardiac Myocytes
Protein Splicing
Genetic Suppression
1 Citation (Scopus)

NURR1 activation in skeletal muscle controls systemic energy homeostasis

Amoasii, L., Sanchez-Ortiz, E., Fujikawa, T., Elmquist, J. K., Bassel-Duby, R. S. & Olson, E. N., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11299-11308 10 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Homeostasis
Glucose
Nuclear Receptor Subfamily 4, Group A, Member 2
Orphan Nuclear Receptors

PAN-INTACT enables direct isolation of lineage-specific nuclei from fibrous tissues

Bhattacharyya, S., Sathe, A. A., Bhakta, M., Xing, C. & Munshi, N. V., Apr 1 2019, In : PloS one. 14, 4, e0214677.

Research output: Contribution to journalArticle

Open Access
Tissue
Chromatin
Transposases
Endothelial cells
cells

Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling

Han, Y., Wang, B., Cho, Y. S., Zhu, J., Wu, J., Chen, Y. & Jiang, J., Sep 9 2019, In : Developmental Cell. 50, 5, p. 610-626.e4

Research output: Contribution to journalArticle

Phosphorylation
Phosphotransferases
Hordeolum
Transcription Factors
Neuroglia

Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility

Altamirano, F., Schiattarella, G. G., French, K. M., Kim, S. Y., Engelberger, F., Kyrychenko, S., Villalobos, E., Tong, D., Schneider, J. W., Ramirez-Sarmiento, C. A., Lavandero, S., Gillette, T. G. & Hill, J. A., Sep 10 2019, In : Circulation. 140, 11, p. 921-936 16 p.

Research output: Contribution to journalArticle

Open Access
Cardiac Myocytes
Reticulum
Action Potentials
Autosomal Dominant Polycystic Kidney
Calcium-Transporting ATPases
2 Citations (Scopus)

Predictive value of single-nucleotide polymorphism signature for recurrence in localised renal cell carcinoma: a retrospective analysis and multicentre validation study

Wei, J. H., Feng, Z. H., Cao, Y., Zhao, H. W., Chen, Z. H., Liao, B., Wang, Q., Han, H., Zhang, J., Xu, Y. Z., Li, B., Wu, J. T., Qu, G. M., Wang, G. P., Liu, C., Xue, W., Liu, Q., Lu, J., Li, C. X., Li, P. X. & 13 others, Zhang, Z. L., Yao, H. H., Pan, Y. H., Chen, W. F., Xie, D., Shi, L., Gao, Z. L., Huang, Y. R., Zhou, F. J., Wang, S. G., Liu, Z-P., Chen, W. & Luo, J. H., Apr 1 2019, In : The Lancet Oncology. 20, 4, p. 591-600 10 p.

Research output: Contribution to journalArticle

Validation Studies
Renal Cell Carcinoma
Multicenter Studies
Single Nucleotide Polymorphism
Recurrence

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

Krah, N. M., Narayanan, S. M., Yugawa, D. E., Straley, J. A., Wright, C. V. E., MacDonald, R. J. & Murtaugh, L. C., Sep 23 2019, In : Developmental Cell. 50, 6, p. 744-754.e4

Research output: Contribution to journalArticle

Acinar Cells
Pancreatic Neoplasms
Carcinogenesis
Genes
Cells
6 Citations (Scopus)

Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program

Russo, I., Cavalera, M., Huang, S., Su, Y., Hanna, A., Chen, B., Shinde, A. V., Conway, S. J., Graff, J. M. & Frangogiannis, N. G., Apr 12 2019, In : Circulation research. 124, 8, p. 1214-1227 14 p.

Research output: Contribution to journalArticle

Myofibroblasts
Transforming Growth Factors
Myocardium
Pressure
Matrix Metalloproteinase 8

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD

Elguindy, M. M., Kopp, F., Goodarzi, M., Rehfeld, F., Thomas, A., Chang, T. C. & Mendell, J. T., Jul 1 2019, In : eLife. 8, e48625.

Research output: Contribution to journalArticle

Open Access
Untranslated RNA
Genomic Instability
Genes
Long Noncoding RNA
Maintenance
6 Citations (Scopus)

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Kopp, F., Elguindy, M. M., Yalvac, M. E., Zhang, H., Chen, B., Gillett, F. A., Lee, S., Sivakumar, S., Yu, H., Xie, Y., Mishra, P., Sahenk, Z. & Mendell, J. T., Feb 8 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Long Noncoding RNA
Premature Aging
Aging of materials
Physiology
Phenotype

Rational Reprogramming of Cellular States by Combinatorial Perturbation

Duan, J., Li, B., Bhakta, M., Xie, S., Zhou, P., Munshi, N. V. & Hon, G., Jun 18 2019, In : Cell Reports. 27, 12, p. 3486-3499.e6

Research output: Contribution to journalArticle

Open Access
Transcription Factors
Regenerative Medicine
Libraries
Cellular Reprogramming
Atlases

Selective targeting of myoblast fusogenic signaling and differentiation-arrest antagonizes rhabdomyosarcoma cells

Granados, V. A., Avirneni-Vadlamudi, U., Dalal, P., Scarborough, S. R., Galindo, K. A., Mahajan, P. & Galindo, R. L., Sep 15 2019, In : Cancer Research. 79, 18, p. 4585-4591 7 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Myoblasts
Cell Lineage
Drosophila
RNA Sequence Analysis