Research Output 1968 2019

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Review article
2019
9 Citations (Scopus)

A Dozen Years of Discovery: Insights into the Physiology and Pharmacology of FGF21

Kliewer, S. A. & Mangelsdorf, D. J., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 246-253 8 p.

Research output: Contribution to journalReview article

Pharmacology
fibroblast growth factor 21
18 Citations (Scopus)

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A. & Chen, Z., Mar 8 2019, In : Science (New York, N.Y.). 363, 6431

Research output: Contribution to journalReview article

Immunity
Inflammation
DNA
Infection
Therapeutics

HDAC inhibition as a therapeutic strategy in myocardial ischemia/reperfusion injury

Xie, M., Tang, Y. & Hill, J. A., Apr 1 2019, In : Journal of Molecular and Cellular Cardiology. 129, p. 188-192 5 p.

Research output: Contribution to journalReview article

Myocardial Reperfusion Injury
Histone Deacetylases
Reperfusion Injury
Myocardial Ischemia
Myocardial Reperfusion

Insights into pediatric rhabdomyosarcoma research: Challenges and goals

Yohe, M. E., Heske, C. M., Stewart, E., Adamson, P. C., Ahmed, N., Antonescu, C. R., Chen, E., Collins, N., Ehrlich, A., Galindo, R. L., Gryder, B. E., Hahn, H., Hammond, S., Hatley, M. E., Hawkins, D. S., Hayes, M. N., Hayes-Jordan, A., Helman, L. J., Hettmer, S., Ignatius, M. S. & 13 others, Keller, C., Khan, J., Kirsch, D. G., Linardic, C. M., Lupo, P. J., Rota, R., Shern, J. F., Shipley, J., Sindiri, S., Tapscott, S. J., Vakoc, C. R., Wexler, L. H. & Langenau, D. M., Jan 1 2019, In : Pediatric Blood and Cancer. 66, 10, e27869.

Research output: Contribution to journalReview article

Rhabdomyosarcoma
irinotecan
Pediatrics
Research
Vincristine
1 Citation (Scopus)

New insights into germ cell tumor genomics

Lafin, J. T., Bagrodia, A., Woldu, S. & Amatruda, J. F., Jan 1 2019, In : Andrology.

Research output: Contribution to journalReview article

Germ Cell and Embryonal Neoplasms
Genomics
Platinum
Immunotherapy
Neoplasms

The fusogenic synapse at a glance

Kim, J. H. & Chen, E., Sep 16 2019, In : Journal of cell science. 132, 18

Research output: Contribution to journalReview article

Open Access
Synapses
Actins
Myoblasts
Drosophila
Actomyosin

Thinking outside of the cell: Secreted protein kinases in bacteria, parasites, and mammals

Park, B. C., Reese, M. & Tagliabracci, V. S., Jan 1 2019, In : IUBMB Life.

Research output: Contribution to journalReview article

Mammals
Protein Kinases
Bacteria
Parasites
Phosphotransferases
2018
6 Citations (Scopus)
Clustered Regularly Interspaced Short Palindromic Repeats
Genetic Testing
Neoplasms
Neoplasm Genes
Mutagenesis
5 Citations (Scopus)

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

Carbone, M., Amelio, I., Affar, E. B., Brugarolas, J. B., Cannon-Albright, L. A., Cantley, L. C., Cavenee, W. K., Chen, Z., Croce, C. M., Andrea, A. D., Gandara, D., Giorgi, C., Jia, W., Lan, Q., Mak, T. W., Manley, J. L., Mikoshiba, K., Onuchic, J. N., Pass, H. I., Pinton, P. & 8 others, Prives, C., Rothman, N., Sebti, S. M., Turkson, J., Wu, X., Yang, H., Yu, H. & Melino, G., Nov 1 2018, In : Cell Death and Differentiation. 25, 11, p. 1885-1904 20 p.

Research output: Contribution to journalReview article

Gene-Environment Interaction
Precision Medicine
Carcinogenesis
Neoplasms
Intrinsic Factor
19 Citations (Scopus)

Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids

Tan, X., Sun, L., Chen, J. & Chen, Z. J., Sep 8 2018, In : Annual Review of Microbiology. 72, p. 447-478 32 p.

Research output: Contribution to journalReview article

Pattern Recognition Receptors
Nucleic Acids
Infection
RNA
Interferon Type I
9 Citations (Scopus)

Enzymes Involved in AMPylation and deAMPylation

Casey, A. K. & Orth, K., Feb 14 2018, In : Chemical Reviews. 118, 3, p. 1199-1215 17 p.

Research output: Contribution to journalReview article

Enzymes
Proteins
Adenosine Monophosphate
Bacteria
260 Citations (Scopus)

Functional Classification and Experimental Dissection of Long Noncoding RNAs

Kopp, F. & Mendell, J. T., Jan 25 2018, In : Cell. 172, 3, p. 393-407 15 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Dissection
Transcriptome
Physiology
Transcription
2 Citations (Scopus)

Genetic and epigenetic regulation of cardiomyocytes in development, regeneration and disease

Cui, M., Wang, Z., Bassel-Duby, R. S. & Olson, E. N., Dec 20 2018, In : Development (Cambridge, England). 145, 24

Research output: Contribution to journalReview article

Cardiac Myocytes
Epigenomics
Regeneration
Myocardial Contraction
Heart Diseases
1 Citation (Scopus)

Ischemic stroke mandates cross-disciplinary collaboration

Fisher, M. & Hill, J. A., Jan 1 2018, In : Circulation. 137, 2, p. 103-105 3 p.

Research output: Contribution to journalReview article

Patent Foramen Ovale
Cardiology
Atrial Fibrillation
Stroke

Let curiosity lead you

Chen, E., Nov 1 2018, In : Molecular Biology of the Cell. 29, 22, p. 2603-2605 3 p.

Research output: Contribution to journalReview article

Exploratory Behavior
Cell Fusion
Cell Biology
Research
23 Citations (Scopus)

mTOR signaling in stem and progenitor cells

Meng, D., Frank, A. R. & Jewell, J. L., Jan 1 2018, In : Development (Cambridge). 145, 1, dev152595.

Research output: Contribution to journalReview article

Sirolimus
Stem Cells
Multipotent Stem Cells
Adult Stem Cells
Autophagy
3 Citations (Scopus)

Myoediting: Toward prevention of muscular dystrophy by therapeutic genome editing

Zhang, Y., Long, C., Bassel-Duby, R. & Olson, E. N., Jul 1 2018, In : Physiological Reviews. 98, 3, p. 1205-1240 36 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Inborn Genetic Diseases
Mutation
CRISPR-Cas Systems
Premature Mortality
3 Citations (Scopus)

Pediatric Germ Cell Tumors: A Developmental Perspective

Pierce, J. L., Frazier, A. L. & Amatruda, J. F., Jan 1 2018, In : Advances in Urology. 2018, 9059382.

Research output: Contribution to journalReview article

Germ Cell and Embryonal Neoplasms
Pediatrics
Germ Cells
Neoplasms
Translational Medical Research
4 Citations (Scopus)
Sensorineural Hearing Loss
Hearing Loss
Neuroglia
Central Nervous System
Spiral Ganglion
3 Citations (Scopus)

Specialized Intercellular Communications via Cytonemes and Nanotubes

Yamashita, Y. M., Inaba, M. & Buszczak, M., Oct 6 2018, In : Annual Review of Cell and Developmental Biology. 34, p. 59-84 26 p.

Research output: Contribution to journalReview article

Nanotubes
Cell Surface Extensions
Membranes
Neoplasms
82 Citations (Scopus)

The cGAS-cGAMP-STI NG pathway connects DNA damage to inflammation, senescence, and cancer

Li, T. & Chen, Z. J., May 1 2018, In : Journal of Experimental Medicine. 215, 5, p. 1287-1299 13 p.

Research output: Contribution to journalReview article

Sexually Transmitted Diseases
DNA Damage
Inflammation
DNA
Neoplasms
2017
39 Citations (Scopus)

Epigenomic and transcriptomic approaches in the post-genomic era: Path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart

Perrino, C., Barabási, A. L., Condorelli, G., Davidson, S. M., De Windt, L., Dimmeler, S., Engel, F. B., Hausenloy, D. J., Hill, J. A., Van Laake, L. W., Lecour, S., Leor, J., Madonna, R., Mayr, M., Prunier, F., Sluijter, J. P. G., Schulz, R., Thum, T., Ytrehus, K. & Ferdinandy, P., 2017, In : Cardiovascular Research. 113, 7, p. 725-736 12 p.

Research output: Contribution to journalReview article

Epigenomics
Cell Biology
Reperfusion Injury
Myocardial Ischemia
Heart Failure

Form(ul)ation of adipocytes by lipids

Lapid, K. & Graff, J. M., Jul 3 2017, In : Adipocyte. 6, 3, p. 176-186 11 p.

Research output: Contribution to journalReview article

Adipocytes
Lipids
Lipid Metabolism
Mass Spectrometry
Homeostasis
1 Citation (Scopus)

Form(ul)ation of adipocytes by lipids

Lapid, K. & Graff, J. M., Jul 3 2017, In : Adipocyte. 6, 3, p. 176-186 11 p.

Research output: Contribution to journalReview article

Open Access
Adipocytes
Lipids
Lipid Metabolism
Mass Spectrometry
Homeostasis
4 Citations (Scopus)

Metabolic control and oxidative stress in pathological cardiac remodelling

Schiattarella, G. G. & Hill, J. A., May 1 2017, In : European Heart Journal. 38, 18, p. 1399-1401 3 p.

Research output: Contribution to journalReview article

Oxidative Stress
4 Citations (Scopus)

Nuclear receptors: Emerging drug targets for parasitic diseases

Wang, Z., Schaffer, N. E., Kliewer, S. A. & Mangelsdorf, D. J., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1165-1171 7 p.

Research output: Contribution to journalReview article

Parasitic Diseases
Cytoplasmic and Nuclear Receptors
Helminths
Pharmaceutical Preparations
Anthelmintics

Science signaling podcast for 16 may 2017: Vibrio rewires host cells

De Nisco, N. J., Orth, K. & VanHook, A. M., May 16 2017, In : Science Signaling. 10, 479, 5621.

Research output: Contribution to journalReview article

Webcasts
Vibrio parahaemolyticus
Vibrio
Virulence Factors
Bacteria
6 Citations (Scopus)

Spermidine Promotes Cardioprotective Autophagy

Tong, D. & Hill, J. A., Apr 14 2017, In : Circulation Research. 120, 8, p. 1229-1231 3 p.

Research output: Contribution to journalReview article

Spermidine
Autophagy
Polyamines
Dietary Supplements
Epidemiologic Studies
5 Citations (Scopus)

Status of Early-Career Academic Cardiology: A Global Perspective

Tong, C. W., Madhur, M. S., Rzeszut, A. K., Abdalla, M., Abudayyeh, I., Alexanderson, E., Buber, J., Feldman, D. N., Gopinathannair, R., Hira, R. S., Kates, A. M., Kessler, T., Leung, S., Raj, S. R., Spatz, E. S., Turner, M. B., Valente, A. M., West, K., Sivaram, C. A., Hill, J. A. & 2 others, Mann, D. L. & Freeman, A. M., Oct 31 2017, In : Journal of the American College of Cardiology. 70, 18, p. 2290-2303 14 p.

Research output: Contribution to journalReview article

National Heart, Lung, and Blood Institute (U.S.)
Organized Financing
Cardiology
Motivation
Organizations
22 Citations (Scopus)

Target and Agent Prioritization for the Children's Oncology Group - National Cancer Institute Pediatric MATCH Trial

Pediatric MATCH Target and Agent Prioritization Committee, May 1 2017, In : Journal of the National Cancer Institute. 109, 5, djw274.

Research output: Contribution to journalReview article

National Cancer Institute (U.S.)
Pediatrics
Therapeutics
Neoplasms
Histiocytosis
7 Citations (Scopus)

The Academic Medical System: Reinvention to Survive the Revolution in Health Care

Academic Cardiology Section Leadership Council of the American College of Cardiology, Mar 14 2017, In : Journal of the American College of Cardiology. 69, 10, p. 1305-1312 8 p.

Research output: Contribution to journalReview article

Delivery of Health Care
Education
Research
2016
10 Citations (Scopus)

Epigenetic regulation in heart failure

Kim, S. Y., Morales, C. R., Gillette, T. G. & Hill, J. A., 2016, In : Current Opinion in Cardiology. 31, 3, p. 255-265 11 p.

Research output: Contribution to journalReview article

Epigenomics
Heart Failure
Untranslated RNA
Neoplastic Stem Cells
Transducers
15 Citations (Scopus)

Genome editing of monogenic neuromuscular diseases: A systematic review

Long, C., Amoasii, L., Bassel-Duby, R. & Olson, E. N., Nov 1 2016, In : JAMA Neurology. 73, 11, p. 1349-1355 7 p.

Research output: Contribution to journalReview article

Neuromuscular Diseases
Clustered Regularly Interspaced Short Palindromic Repeats
Spinal Muscular Atrophy
Duchenne Muscular Dystrophy
Amyotrophic Lateral Sclerosis
23 Citations (Scopus)

Inhibiting cancer cell hallmark features through nuclear export inhibition

Sun, Q., Chen, X., Zhou, Q., Burstein, E., Yang, S. & Jia, D., Jan 1 2016, In : Signal Transduction and Targeted Therapy. 1, 16010.

Research output: Contribution to journalReview article

Open Access
Cell Nucleus Active Transport
Neoplasms
Maintenance
Clinical Trials
Research
6 Citations (Scopus)

Keeping stem cells under control: New insights into the mechanisms that limit niche-stem cell signaling within the reproductive system

Inaba, M., Yamashita, Y. M. & Buszczak, M., Aug 1 2016, In : Molecular Reproduction and Development. 83, 8, p. 675-683 9 p.

Research output: Contribution to journalReview article

Stem Cell Niche
Stem Cells
Adult Stem Cells
Cell Communication
Cell Self Renewal
133 Citations (Scopus)

Membrane fission by dynamin: what we know and what we need to know

Antonny, B., Burd, C., De Camilli, P., Chen, E., Daumke, O., Faelber, K., Ford, M., Frolov, V. A., Frost, A., Hinshaw, J. E., Kirchhausen, T., Kozlov, M. M., Lenz, M., Low, H. H., McMahon, H., Merrifield, C., Pollard, T. D., Robinson, P. J., Roux, A. & Schmid, S. L., Nov 2 2016, In : EMBO Journal. 35, 21, p. 2270-2284 15 p.

Research output: Contribution to journalReview article

Dynamins
Membranes
Guanosine Triphosphate
GTP Phosphohydrolases
Muscle Contraction
10 Citations (Scopus)

Paediatric extracranial germ-cell tumours

Shaikh, F., Murray, M. J., Amatruda, J. F., Coleman, N., Nicholson, J. C., Hale, J. P., Pashankar, F., Stoneham, S. J., Poynter, J. N., Olson, T. A., Billmire, D. F., Stark, D., Rodriguez-Galindo, C. & Frazier, A. L., Apr 1 2016, In : The Lancet Oncology. 17, 4, p. e149-e162

Research output: Contribution to journalReview article

Germ Cell and Embryonal Neoplasms
Pediatrics
Poisons
Tumor Biomarkers
Platinum
4 Citations (Scopus)

Physiological, pathological, and engineered cell identity reprogramming in the central nervous system

Smith, D. K., Wang, L. L. & Zhang, C. L., Jul 1 2016, In : Wiley Interdisciplinary Reviews: Developmental Biology. 5, 4, p. 499-517 19 p.

Research output: Contribution to journalReview article

Central Nervous System
Multipotent Stem Cells
Neurons
Neural Stem Cells
Neurogenesis
318 Citations (Scopus)

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing

Chen, Q., Sun, L. & Chen, Z. J., Sep 20 2016, In : Nature Immunology. 17, 10, p. 1142-1149 8 p.

Research output: Contribution to journalReview article

DNA
GMP synthase (glutamine-hydrolyzing)
Second Messenger Systems
Innate Immunity
Nucleic Acids
6 Citations (Scopus)

Regulation of cardiomyocyte autophagy by calcium

Shaikh, S., Troncoso, R., Criollo, A., Bravo-Sagua, R., García, L., Morselli, E., Cifuentes, M., Quest, A. F. G., Hill, J. A. & Lavandero, S., Apr 15 2016, In : American Journal of Physiology - Endocrinology and Metabolism. 310, 8, p. E587-E596

Research output: Contribution to journalReview article

Autophagy
Cardiac Myocytes
Calcium
Calcium Signaling
Cell Cycle Checkpoints
18 Citations (Scopus)

Signaling by Cellular Protrusions: Keeping the Conversation Private

Buszczak, M., Inaba, M. & Yamashita, Y. M., Jul 1 2016, In : Trends in Cell Biology. 26, 7, p. 526-534 9 p.

Research output: Contribution to journalReview article

Cell Surface Extensions
Nanotubes
Stem Cells
Stem Cell Niche
Pseudopodia
5 Citations (Scopus)

The bioengineered kidney: Science or science fiction?

Oxburgh, L. & Carroll, T. J., Jul 1 2016, In : Current Opinion in Nephrology and Hypertension. 25, 4, p. 343-347 5 p.

Research output: Contribution to journalReview article

Kidney
Bioengineering
Podocytes
Stem Cells
Endothelial Cells
3 Citations (Scopus)

The stress response paradox: fighting degeneration at the cost of cancer

Arneaud, S. L. B. & Douglas, P. M., Nov 1 2016, In : FEBS Journal. 283, 22, p. 4047-4055 9 p.

Research output: Contribution to journalReview article

Neoplasms
Biological Phenomena
Research
Cell death
Biological systems
2015
15 Citations (Scopus)

In Vivo Reprogramming for Brain and Spinal Cord Repair

Chen, G., Wernig, M., Berninger, B., Nakafuku, M., Parmar, M. & Zhang, C. L., Sep 1 2015, In : eNeuro. 2, 5

Research output: Contribution to journalReview article

Spinal Cord Regeneration
Cell Transplantation
Brain
Spinal Cord
Neurons
82 Citations (Scopus)

Mechanisms of myoblast fusion during muscle development

Kim, J. H., Jin, P., Duan, R. & Chen, E., Jun 1 2015, In : Current Opinion in Genetics and Development. 32, p. 162-170 9 p.

Research output: Contribution to journalReview article

Muscle Development
Myoblasts
Muscle Cells
Genetic Models
Zebrafish
2013
191 Citations (Scopus)

Nutrient signaling to mTOR and cell growth

Jewell, J. L. & Guan, K. L., May 1 2013, In : Trends in Biochemical Sciences. 38, 5, p. 233-242 10 p.

Research output: Contribution to journalReview article

Cell growth
Sirolimus
Nutrients
Food
Growth
68 Citations (Scopus)

Secreted protein kinases

Tagliabracci, V. S., Pinna, L. A. & Dixon, J. E., Mar 1 2013, In : Trends in Biochemical Sciences. 38, 3, p. 121-130 10 p.

Research output: Contribution to journalReview article

Protein Kinases
Caseins
Biomineralization
Proteins
Phosphoproteins
2012
257 Citations (Scopus)

Glycogen and its metabolism: Some new developments and old themes

Roach, P. J., Depaoli-Roach, A. A., Hurley, T. D. & Tagliabracci, V. S., Feb 1 2012, In : Biochemical Journal. 441, 3, p. 763-787 25 p.

Research output: Contribution to journalReview article

Glycogen
Metabolism
Glycogen Synthase
Epinephrine
Lafora Disease
2011

Invasive podosomes and myoblast fusion.

Chen, E. H., Jan 1 2011, In : Current Topics in Membranes. 68, p. 235-258 24 p.

Research output: Contribution to journalReview article

Cell Surface Extensions
Biological Models
Cell Fusion
Myoblasts
Porosity
2010
68 Citations (Scopus)
Qa-SNARE Proteins
Exocytosis
SNARE Proteins
Insulin
Glucose