Research Output 1969 2019

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2017

Membrane extraction of HMG CoA reductase as determined by susceptibility of lumenal epitope to in vitro protease digestion

Morris, L. L. & DeBose-Boyd, R. A., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1583. p. 193-199 7 p. (Methods in Molecular Biology; vol. 1583).

Research output: Chapter in Book/Report/Conference proceedingChapter

Hydroxymethylglutaryl CoA Reductases
Epitopes
Digestion
Peptide Hydrolases
Endoplasmic Reticulum-Associated Degradation
2013

Regulated Intramembrane Proteolysis

Ye, J., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 50-55 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteolysis
Peptide Hydrolases
Animals
Cells
Membranes
3 Citations (Scopus)

Steroid 5α-Reductase 2 Deficiency

Russell, D. W. & Wilson, J. D., Sep 2013, Genetic Steroid Disorders. Elsevier Inc., p. 199-214 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oxidoreductases
Dihydrotestosterone
Steroids
Prostatic Diseases
Genes
2011
45 Citations (Scopus)

Trypanosoma cruzi utilizes the host low Density Lipoprotein receptor in invasion

Nagajyothi, F., Weiss, L. M., Silver, D. L., Desruisseaux, M. S., Scherer, P. E., Herz, J. & Tanowitz, H. B., Feb 2011, PLoS Neglected Tropical Diseases. 2 ed. Vol. 5. e953

Research output: Chapter in Book/Report/Conference proceedingChapter

LDL Receptors
Trypanosoma cruzi
Parasites
Vacuoles
Infection
2010

The SREBP pathway. gene regulation through sterol sensing and gated protein trafficking

Radhakrishnan, A., Sun, L. P., Espenshade, P. J., Goldstein, J. L. & Brown, M. S., 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 3. p. 2505-2510 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sterol Regulatory Element Binding Proteins
Sterols
Protein Transport
Gene expression
Cholesterol
2008
3 Citations (Scopus)

Apolipoprotein e receptor 2 and very-low-density lipoprotein receptor: An overview

Bock, H. H. & Herz, J., 2008, Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease. Springer New York, p. 15-35 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Apolipoproteins
LDL Receptors
LDL-Receptor Related Proteins
Lipoprotein Receptors
Neuronal Plasticity
2007
6 Citations (Scopus)

Conditional animal models for the study of lipid metabolism and lipid disorders

Bock, H. H., Herz, J. & May, P., 2007, Handbook of Experimental Pharmacology. Vol. 178. p. 407-439 33 p. (Handbook of Experimental Pharmacology; vol. 178).

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipid Metabolism Disorders
Animals
Animal Models
Genes
Lipids
2006
3 Citations (Scopus)

Lessons from sleepy mice: Narcolepsy-cataplexy and the orexin neuropeptide system

Willie, J. T. & Yanagisawa, M., Jan 1 2006, Narcolepsy and Hypersomnia. CRC Press, p. 257-278 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cataplexy
Narcolepsy
Neuropeptides
Orexin Receptors
Sleep
2005
1 Citation (Scopus)

Rodent models of human narcolepsy-cataplexy

Sakurai, T., Yanagisawa, M. & Mieda, M., 2005, Hypocretins: Integrators of Physiological Functions. Springer US, p. 27-38 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cataplexy
Narcolepsy
Rodentia
Sleep
REM Sleep
20 Citations (Scopus)

The LIPID maps approach to lipidomics

Dennis, E. A., Alex Brown, H., Deems, R. A., Glass, C. K., Merrill, A. H., Murphy, R. C., Raetz, C. R. H., Shaw, W., Subramaniam, S., Russell, D. W., Van Nieuwenhze, M. S., White, S. H., Witztum, J. L. & Wooley, J., Jan 1 2005, Functional Lipidomics. CRC Press, p. 1-15 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipids
lipids
Glues
Metabolites
adhesives
2003

SREPBs: Gene Regulation through Controlled Protein Trafficking

Espenshade, P. J., Goldstein, J. L. & Brown, M. S., Nov 7 2003, Handbook of Cell Signaling. Elsevier Inc., Vol. 3-3. p. 353-358 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gene expression
Proteins
2002

Chapter V Orexin receptors

Sakurai, T., Hervieu, G. & Yanagisawa, M., 2002, Handbook of Chemical Neuroanatomy. Vol. 20. p. 245-322 78 p. (Handbook of Chemical Neuroanatomy; vol. 20).

Research output: Chapter in Book/Report/Conference proceedingChapter

Orexin Receptors
2001
11 Citations (Scopus)

3 Positional candidate gene cloning of CLN1

Hofmann, S. L., Das, A. K., Lu, J. Y. & Soyombo, A. A., 2001, Advances in Genetics. Vol. 45. p. 69-92 24 p. (Advances in Genetics; vol. 45).

Research output: Chapter in Book/Report/Conference proceedingChapter

Organism Cloning
Neuronal Ceroid-Lipofuscinoses
Genes
Proteins
Mutation
1982
5 Citations (Scopus)

Receptor-mediated endocytosis and the structural organization of the cell membrane

Brown, M. S. & Goldstein, J. L., 1982, National Cancer Institute Monograph. Vol. No. 60. p. 3-6 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Endocytosis
Cell Membrane
Biological Phenomena
Transport Vesicles
Extracellular Fluid
1980
24 Citations (Scopus)

LDL receptors in coated vesicles isolated from bovine adrenal cortex: Binding sites unmasked by detergent treatment

Mello, R. J., Brown, M. S., Goldstein, J. L. & Anderson, R. G. W., 1980, Cell. 3 ed. Vol. 20. p. 829-837 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Coated Vesicles
LDL Receptors
Adrenal Cortex
Detergents
Binding Sites
340 Citations (Scopus)

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages

Brown, M. S., Basu, S. K., Falck, J. R., Ho, Y. K. & Goldstein, J. L., 1980, Journal of Supramolecular and Cellular Biochemistry. 1 ed. Vol. 13. p. 67-81 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lipoproteins
Macrophages
Binding Sites
oxidized low density lipoprotein
1979
83 Citations (Scopus)

Reconstituted low density lipoprotein: A vehicle for the delivery of hydrophobic fluorescent probes to cells

Krieger, M., Smith, L. C., Anderson, R. G. W., Goldstein, J. L., Kao, Y. J., Pownall, H. J., Gotto, A. M. & Brown, M. S., 1979, Journal of Supramolecular and Cellular Biochemistry. 4 ed. Vol. 10. p. 467-478 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fluorescent Dyes
LDL Lipoproteins
1978
59 Citations (Scopus)

Familial hypercholesterolemia: Pathogenesis of a receptor disease

Goldstein, J. L. & Brown, M. S., 1978, Johns Hopkins Medical Journal. 1 ed. Vol. 143. p. 8-16 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hyperlipoproteinemia Type II
LDL Lipoproteins
Gene Dosage
Cell Surface Receptors
LDL Cholesterol
45 Citations (Scopus)

Inhibition of the binding of low-density lipoprotein to its cell surface receptor in human fibroblasts by positively charged proteins

Brown, M. S., Deuel, T. F., Basu, S. K. & Goldstein, J. L., 1978, Journal of Supramolecular and Cellular Biochemistry. 3 ed. Vol. 8. p. 223-234 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Surface Receptors
Fibroblasts
LDL Lipoproteins
Lysine
Protamines

Mutations affecting the binding, internalization, and lysosomal hydrolysis of low density lipoprotein in cultured human fibroblasts, lymphocytes, and aortic smooth muscle cells

Brown, M. S., Anderson, R. G. W. & Goldstein, J. L., 1978, Progress in Clinical and Biological Research. Vol. VOL.22. p. 25-34 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

LDL Lipoproteins
Smooth Muscle Myocytes
Hydrolysis
Fibroblasts
Lymphocytes
1977
8 Citations (Scopus)

Mutations affecting the binding, internalization, and lysosomal hydrolysis of low density lipoprotein in cultured human fibroblasts, lymphocytes, and aortic smooth muscle cells

Brown, M. S., Anderson, R. G. W. & Goldstein, J. L., 1977, Journal of Supramolecular and Cellular Biochemistry. 1 ed. Vol. 6. p. 85-94 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Lymphocytes
Fibroblasts
LDL Lipoproteins
Metabolism
Smooth Muscle Myocytes
1974
6 Citations (Scopus)

Expression of the familial hypercholesterolemia gene in heterozygotes: model for a dominant disorder in man

Goldstein, J. L. & Brown, M. S., 1974, Transactions of the Association of American Physicians. Vol. 87. p. 120-131 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hyperlipoproteinemia Type II
Heterozygote
Dominant Genes
Enzymes
Genes