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[36] Purification of the LDL receptor

Schneider, W. J., Goldstein, J. L. & Brown, M. S., Jan 1 1985, In : Methods in Enzymology. 109, C, p. 405-417 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

[4] 3-Hydroxy-3-methylglutaryl-CoA reductases from pea seedlings

Russell, D. W., Jan 1 1985, In : Methods in Enzymology. 110, C, p. 26-40 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

[An improved method for isolation of single atrial myocyte from human heart].

Li, M. L., Zeng, X. R., Yang, Y., Liu, Z. F., Ding, Y. Y., Zhou, W. & Pei, J., Dec 25 2007, In : Sheng li xue bao : [Acta physiologica Sinica]. 59, 6, p. 858-864 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

[New advancement of genetically manipulated mouse models in dyslipidemia and atherosclerosis].

Ding, Y. Y. & Liu, G. Q., Apr 1 2009, In : Sheng li ke xue jin zhan [Progress in physiology]. 40, 2, p. 151-153 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

17β-hydroxysteroid dehydrogenase 3 deficiency in women

Mendonca, B. B., Arnhold, I. J. P., Bloise, W., Andersson, S., Russell, D. W. & Wilson, J. D., Feb 17 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 2, p. 802-804 3 p.

Research output: Contribution to journalArticle

43 Scopus citations

1993 Aspen Cholesterol/Bile Acid Conference: Diet and Gene Interactions in Cholesterol Metabolism

Rudel, L. L., Newton, R., Hamilton, R., Deckelbaum, R. J. & Hobbs, H. H., Jan 1 1994, In : Journal of lipid research. 35, 6, p. 1122-1128 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

Shibata, N., Carlin, A. F., Spann, N. J., Saijo, K., Morello, C. S., McDonald, J. G., Romanoski, C. E., Maurya, M. R., Kaikkonen, M. U., Lam, M. T., Crotti, A., Reichart, D., Fox, J. N., Quehenberger, O., Raetz, C. R. H., Cameron Sullards, M., Murphy, R. C., Merrill, A. H., Alex Brown, H., Dennis, E. A. & 6 others, Fahy, E., Subramaniam, S., Cavener, D. R., Spector, D. H., Russell, D. W. & Glassa, C. K., Dec 13 2013, In : Journal of Biological Chemistry. 288, 50, p. 35812-35823 12 p.

Research output: Contribution to journalArticle

32 Scopus citations
186 Scopus citations

25-hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

Reboldi, A., Dang, E. V., McDonald, J. G., Liang, G., Russell, D. W. & Cyster, J. G., Aug 8 2014, In : Science. 345, 6197, p. 679-684 6 p.

Research output: Contribution to journalArticle

199 Scopus citations
34 Scopus citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/α2-macroglobulin receptor

Herz, J., Goldstein, J. L., Strickland, D. K., Ho, Y. K. & Brown, M. S., Jan 1 1991, In : Journal of Biological Chemistry. 266, 31, p. 21232-21238 7 p.

Research output: Contribution to journalArticle

452 Scopus citations
12 Scopus citations

3 Hydroxy 3 methylglutaryl coenzyme A reductase. Solubilization and purification of a cold sensitive microsomal enzyme

Brown, M. S., Dana, S. E., Dietschy, J. M. & Siperstein, M. D., Dec 1 1973, In : Journal of Biological Chemistry. 248, 13, p. 4731-4738 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

3 Hydroxy 3 methylglutaryl coenzyme A reductase activity in human hair roots

Brannan, P. G., Goldstein, J. J. & Brown, M. S., Jan 1 1975, In : Journal of lipid research. 16, 1, p. 7-11 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter

Südhof, T. C., Russell, D. W., Brown, M. S. & Goldstein, J. L., Mar 27 1987, In : Cell. 48, 6, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

133 Scopus citations

5α-reduced androgens play a key role in murine parturition

Mahendroo, M. S., Cala, K. M. & Russell, D. W., Apr 18 1996, In : Molecular Endocrinology. 10, 4, p. 380-392 13 p.

Research output: Contribution to journalArticle

168 Scopus citations

5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription

Osborne, T. F., Goldstein, J. L. & Brown, M. S., Aug 1985, In : Cell. 42, 1, p. 203-212 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity

Schmidt, R. J., Ficorilli, J. V., Zhang, Y., Bramlett, K. S., Beyer, T. P., Borchert, K., Dowless, M. S., Houck, K. A., Burris, T. P., Eacho, P. I., Liang, G., Guo, L. W., Wilson, W. K., Michael, L. F. & Cao, G., May 1 2006, In : Journal of lipid research. 47, 5, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

A 25-hydroxycholesterol-resistant cell line deficient in acyl-coA:cholesterol acyltransferase

Metherall, J. E., Ridgway, N. D., Dawson, P. A., Goldstein, J. L. & Brown, M. S., Sep 23 1991, In : Journal of Biological Chemistry. 266, 19, p. 12734-12740 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion

Graf, G. A., Yu, L., Li, W. P., Gerard, R., Tuma, P. L., Cohen, J. C. & Hobbs, H. H., Nov 28 2003, In : Journal of Biological Chemistry. 278, 48, p. 48275-48282 8 p.

Research output: Contribution to journalArticle

313 Scopus citations

ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile

Langheim, S., Yu, L., Von Bergmann, K., Lütjohann, D., Xu, F., Hobbs, H. H. & Cohen, J. C., Aug 1 2005, In : Journal of lipid research. 46, 8, p. 1732-1738 7 p.

Research output: Contribution to journalArticle

65 Scopus citations

Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

Guertin, D. A., Stevens, D. M., Thoreen, C. C., Burds, A. A., Kalaany, N. Y., Moffat, J., Brown, M., Fitzgerald, K. J. & Sabatini, D. M., Dec 1 2006, In : Developmental cell. 11, 6, p. 859-871 13 p.

Research output: Contribution to journalArticle

973 Scopus citations

Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis

Tawaramoto, K., Kotani, K., Hashiramoto, M., Kanda, Y., Nagare, T., Sakaue, H., Ogawa, W., Emoto, N., Yanagisawa, M., Noda, T., Kasuga, M. & Kaku, K., Jan 2012, In : Molecular Endocrinology. 26, 1, p. 95-109 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ablation of central serotonergic neurons decreased REM sleep and attenuated arousal response

Iwasaki, K., Komiya, H., Kakizaki, M., Miyoshi, C., Abe, M., Sakimura, K., Funato, H. & Yanagisawa, M., Aug 7 2018, In : Frontiers in Neuroscience. 12, AUG, 535.

Research output: Contribution to journalArticle

8 Scopus citations

Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice

Johnson, E. B., Hammer, R. E. & Herz, J., Nov 15 2005, In : Human molecular genetics. 14, 22, p. 3523-3538 16 p.

Research output: Contribution to journalArticle

97 Scopus citations

Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: Morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice

Gebhardt, C., Del Turco, D., Drakew, A., Tielsch, A., Herz, J., Frotscher, M. & Deller, T., Apr 8 2002, In : Journal of Comparative Neurology. 445, 3, p. 278-292 15 p.

Research output: Contribution to journalArticle

Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: Morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice

Gebhardt, C., Del Turco, D., Drakew, A., Tielsch, A., Herz, J., Frotscher, M. & Deller, T., Apr 8 2002, In : Journal of Comparative Neurology. 445, 3, p. 278-292 15 p.

Research output: Contribution to journalArticle

25 Scopus citations

Abnormal response of melanin-concentrating hormone deficient mice to fasting: Hyperactivity and rapid eye movement sleep suppression

Willie, J. T., Sinton, C. M., Maratos-Flier, E. & Yanagisawa, M., Oct 28 2008, In : Neuroscience. 156, 4, p. 819-829 11 p.

Research output: Contribution to journalArticle

104 Scopus citations

Absence of cardiotrophin 1 is associated with decreased age-dependent arterial stiffness and increased longevity in mice

López-Andrés, N., Calvier, L., Labat, C., Fay, R., Díez, J., Benetos, A., Zannad, F., Lacolley, P. & Rossignol, P., Jan 2013, In : Hypertension. 61, 1, p. 120-129 10 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Absence of P-selectin delays fatty streak formation in mice

Johnson, R. C., Chapman, S. M., Dong, Z. M., Ordovas, J. M., Mayadas, T. N., Herz, J., Hynes, R. O., Schaefer, E. J. & Wagner, D. D., Mar 1 1997, In : Journal of Clinical Investigation. 99, 5, p. 1037-1043 7 p.

Research output: Contribution to journalArticle

Open Access
204 Scopus citations

A case-control study on the relationship between HDL2b and non-alcoholic fatty liver disease in Chinese type 2 diabetic patients

Ma, Y. H., Zhao, L., Xian, X. D., Yang, D., Huang, W., Wang, Y. H., Mueller, O., Chang, E., Konigshofer, Y., Van-Cleve, M., Liu, G. & Yang, J. K., Sep 1 2009, In : Clinical Chemistry and Laboratory Medicine. 47, 9, p. 1067-1072 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

Sever, N., Yang, T., Brown, M. S., Goldstein, J. L. & DeBose-Boyd, R. A., Jan 1 2003, In : Molecular cell. 11, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

249 Scopus citations

Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice

Guan, H. P., Goldstein, J. L., Brown, M. S. & Liang, G., Sep 4 2009, In : Journal of Biological Chemistry. 284, 36, p. 24644-24652 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
58 Scopus citations

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

Berge, K. E., Tian, H., Graf, G. A., Yu, L., Grishin, N. V., Schultz, J., Kwiterovich, P., Shan, B., Barnes, R. & Hobbs, H. H., Dec 1 2000, In : Science. 290, 5497, p. 1771-1775 5 p.

Research output: Contribution to journalArticle

1224 Scopus citations

Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis

BasuRay, S., Wang, Y., Smagris, E., Cohen, J. C. & Hobbs, H. H., May 7 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 19, p. 9521-9526 6 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Acetate dependence of tumors

Comerford, S. A., Huang, Z., Du, X., Wang, Y., Cai, L., Witkiewicz, A., Walters, H., Tantawy, M. N., Fu, A., Manning, H. C., Horton, J. D., Hammer, R. E., McKnight, S. L. & Tu, B. P., Dec 18 2014, In : Cell. 159, 7, p. 1591-1602 12 p.

Research output: Contribution to journalArticle

257 Scopus citations

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation

Kim, C. W., Addy, C., Kusunoki, J., Anderson, N. N., Deja, S., Fu, X., Burgess, S. C., Li, C., Chakravarthy, M., Previs, S., Milstein, S., Fitzgerald, K., Kelley, D. E. & Horton, J. D., Aug 1 2017, In : Cell Metabolism. 26, 2, p. 394-406.e6

Research output: Contribution to journalArticle

69 Scopus citations

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

Davis, C. G., Goldstein, J. L., Südhof, T. C., Anderson, R. G. W., Russell, D. W. & Brown, M. S., Jan 1 1987, In : Nature. 326, 6115, p. 760-765 6 p.

Research output: Contribution to journalArticle

278 Scopus citations

Acid regulation of NaDC-1 requires a functional endothelin B receptor

Liu, L., Zacchia, M., Tian, X., Wan, L., Sakamoto, A., Yanagisawa, M., Alpern, R. J. & Preisig, P. A., Nov 2010, In : Kidney international. 78, 9, p. 895-904 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

A common allele on chromosome 9 associated with coronary heart disease

McPherson, R., Pertsemlidis, A., Kavaslar, N., Stewart, A., Roberts, R., Cox, D. R., Hinds, D. A., Pennacchio, L. A., Tybjaerg-Hansen, A., Folsom, A. R., Boerwinkle, E., Hobbs, H. H. & Cohen, J. C., Jun 8 2007, In : Science. 316, 5830, p. 1488-1491 4 p.

Research output: Contribution to journalArticle

1310 Scopus citations

A comprehensive classification system for lipids

Fahy, E., Subramaniam, S., Brown, H. A., Glass, C. K., Merrill, A. H., Murphy, R. C., Raetz, C. R. H., Russell, D. W., Seyama, Y., Shaw, W., Shimizu, T., Spener, F., Van Meer, G., VanNieuwenhze, M. S., White, S. H., Witztum, J. L. & Dennis, E. A., 2005, In : Journal of lipid research. 46, 5, p. 839-861 23 p.

Research output: Contribution to journalArticle

820 Scopus citations

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma

McDonald, J. G., Smith, D. D., Stiles, A. R. & Russell, D. W., Jul 1 2012, In : Journal of lipid research. 53, 7, p. 1399-1409 11 p.

Research output: Contribution to journalArticle

113 Scopus citations

A consensus definitive classification of scavenger receptors and their roles in health and disease

PrabhuDas, M. R., Baldwin, C. L., Bollyky, P. L., Bowdish, D. M. E., Drickamer, K., Febbraio, M., Herz, J., Kobzik, L., Krieger, M., Loike, J., McVicker, B., Means, T. K., Moestrup, S. K., Post, S. R., Sawamura, T., Silverstein, S., Speth, R. C., Telfer, J. C., Thiele, G. M., Wang, X. Y. & 2 others, Wright, S. D. & El Khoury, J., May 15 2017, In : Journal of Immunology. 198, 10, p. 3775-3789 15 p.

Research output: Contribution to journalArticle

80 Scopus citations

A consensus sequence in the endothelin-B receptor second intracellular loop is required for NHE3 activation by endothelin-1

Laghmani, K., Sakamoto, A., Yanagisawa, M., Preisig, P. A. & Alpern, R. J., Apr 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 4 57-4, p. F732-F739

Research output: Contribution to journalArticle

11 Scopus citations
527 Scopus citations

Activation of ERK signaling upon alternative protease nexin-1 internalization mediated by syndecan-1

Li, X., Herz, J. & Monard, D., Oct 15 2006, In : Journal of Cellular Biochemistry. 99, 3, p. 936-951 16 p.

Research output: Contribution to journalArticle

24 Scopus citations

Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

Tanaka, T., Yamamoto, J., Iwasaki, S., Asaba, H., Hamura, H., Ikeda, Y., Watanabe, M., Magoori, K., Ioka, R. X., Tachibana, K., Watanabe, Y., Uchiyama, Y., Sumi, K., Iguchi, H., Ito, S., Doi, T., Hamakubo, T., Naito, M., Auwerx, J., Yanagisawa, M. & 2 others, Kodama, T. & Sakai, J., Dec 23 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 26, p. 15924-15929 6 p.

Research output: Contribution to journalArticle

657 Scopus citations