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Regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes

Ho, Y. K., Brown, M. S., Bilheimer, D. W. & Goldstein, J. L., 1976, In : Journal of Clinical Investigation. 58, 6, p. 1465-1474 10 p.

Research output: Contribution to journalArticle

Open Access
164 Scopus citations

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans

Goldstein, J. L., Basu, S. K., Brunschede, G. Y. & Brown, M. S., Jan 1976, In : Cell. 7, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

351 Scopus citations

Restoration of a regulatory response to low density lipoprotein in acid lipase deficient human fibroblasts

Brown, M. S., Sobhani, M. K., Brunschede, G. Y. & Goldstein, J. L., Dec 1 1976, In : Journal of Biological Chemistry. 251, 11, p. 3277-3286 10 p.

Research output: Contribution to journalArticle

34 Scopus citations
46 Scopus citations
1975

3 Hydroxy 3 methylglutaryl coenzyme A reductase activity in human hair roots

Brannan, P. G., Goldstein, J. J. & Brown, M. S., Jan 1 1975, In : Journal of lipid research. 16, 1, p. 7-11 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Cholesterol ester formation in cultured human fibroblasts. Stimulation by oxygenated sterols

Brown, M. S., Dana, S. E. & Goldstein, J. L., Dec 1 1975, In : Journal of Biological Chemistry. 250, 10, p. 4025-4027 3 p.

Research output: Contribution to journalArticle

242 Scopus citations

Familial pseudomembranous colitis and its relation to lincomycin therapy

Harrod, M. J. E., Brown, M. S., Weinberg, A. G., Harkness, W. N. & Goldstein, J. L., Sep 1 1975, In : The American Journal of Digestive Diseases. 20, 9, p. 808-812 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic and hormonal control of male sexual differentiation

Goldstein, J. L. & Wilson, J. D., Apr 1975, In : Journal of cellular physiology. 85, 1 S, p. 365-377 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
Open Access
106 Scopus citations

Homozygous familial hypercholesterolemia (receptor negative type). Repository identification No. GM 361

Goldstein, J. L., Brown, M. S., Greene, A. E. & Coriell, L. L., Dec 1 1975, In : Cytogenetics and Cell Genetics. 15, 5, p. 357-359 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
23 Scopus citations
185 Scopus citations

Linkage investigation of a large family with Reifenstein's syndrome

Ott, J., Goldstein, J. L. & Harrod, M. J., Apr 1975, In : Clinical Genetics. 7, 4, p. 342-344 3 p.

Research output: Contribution to journalArticle

4 Scopus citations
10 Scopus citations

Prolonged hypouricemia associated with acute chlorprothixene ingestion

Weinshilboum, R. M., Goldstein, J. L. & Kelley, W. N., Jan 1 1975, In : Arthritis & Rheumatism. 18, 1 S, p. 739-742 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
162 Scopus citations
Open Access
141 Scopus citations

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

Brown, M. S. & Goldstein, J. L., Nov 1975, In : Cell. 6, 3, p. 307-316 10 p.

Research output: Contribution to journalArticle

303 Scopus citations
265 Scopus citations
Open Access
177 Scopus citations

Steroid requirements for suppression of HMG CoA reductase activity in cultured human fibroblasts.

Goldstein, J. L., Faust, J. R., Brunschede, G. Y. & Brown, M. S., 1975, In : Advances in experimental medicine and biology. 63, p. 77-84 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Use of mutant fibroblasts in the analysis of the regulation of cholesterol metabolism in human cells

Brown, M. S., Brannan, P. G., Bohmfalk, H. A., Brunschede, G. Y., Dana, S. E., Helgeson, J. & Goldstein, J. L., Apr 1975, In : Journal of Cellular Physiology. 85, 1 S, p. 425-436 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Effect of alterations of the specific activity of the intracellular acetyl CoA pool on apparent rates of hepatic cholesterogenesis

Dietschy, J. M. & Brown, M. S., Dec 1 1974, In : Journal of lipid research. 15, 5, p. 508-516 9 p.

Research output: Contribution to journalArticle

94 Scopus citations
Open Access
174 Scopus citations

Expression of the familial hypercholesterolemia gene in herozygotes: Mechanism for a dominant disorder in man

Brown, M. S. & Goldstein, J. L., Jan 1 1974, In : Science. 185, 4145, p. 61-63 3 p.

Research output: Contribution to journalArticle

149 Scopus citations
Open Access
356 Scopus citations
145 Scopus citations

Familial Incomplete Male Pseudohermaphroditism, Type 2: Decreased Dihydrotestosterone Formation in Pseudovaginal Perineoscrotal Hypospadias

Walsh, P. C., Madden, J. D., Harrod, M. J., Goldstein, J. L., MacDonald, P. C. & Wilson, J. D., Oct 31 1974, In : New England Journal of Medicine. 291, 18, p. 944-949 6 p.

Research output: Contribution to journalArticle

374 Scopus citations
16 Scopus citations

Linkage studies in a large kindred with familial hypercholesterolemia

Ott, J., Schrott, H. G., Goldstein, J. L., Hazzard, W. R., Allen, F. H., Falk, C. T. & Motulsky, A. G., Dec 1 1974, In : American Journal of Human Genetics. 26, 5, p. 598-603 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Plasma lipid levels and coronary heart disease in adult relatives of newborns with normal and elevated cord blood lipids

Goldstein, J. L., Albers, J. J., Schrott, H. G., Hazzard, W. R., Bierman, E. L. & Motulsky, A. G., Dec 1 1974, In : American Journal of Human Genetics. 26, 6, p. 727-735 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Properties of 3 hydroxy 3 methylglutaryl coenzyme A reductase solubilized from rat liver and hepatoma

Brown, M. S., Dana, S. E. & Siperstein, M. D., Dec 1 1974, In : Journal of Biological Chemistry. 249, 20, p. 6585-6589 5 p.

Research output: Contribution to journalArticle

17 Scopus citations
291 Scopus citations

Stimulation of the synthesis of very low density lipoproteins in rooster liver by estradiol

Luskey, K. L., Brown, M. S. & Goldstein, J. L., Dec 1 1974, In : Journal of Biological Chemistry. 249, 18, p. 5939-5947 9 p.

Research output: Contribution to journalArticle

82 Scopus citations
347 Scopus citations
1973

3 Hydroxy 3 methylglutaryl coenzyme A reductase. Solubilization and purification of a cold sensitive microsomal enzyme

Brown, M. S., Dana, S. E., Dietschy, J. M. & Siperstein, M. D., Dec 1 1973, In : Journal of Biological Chemistry. 248, 13, p. 4731-4738 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Cystathionine synthase activity in human leukocyte cultures.

Gartler, S. M., Campbell, B. K. & Goldstein, J. L., Jan 1 1973, In : Birth defects original article series. 9, 1, p. 155-159 5 p.

Research output: Contribution to journalArticle

Development of increased cytoplasmic binding of androgen in the submandibular gland of the mouse with testicular feminization

Dunn, J. F., Goldstein, J. L. & Wilson, J. D., Jan 1 1973, In : Journal of Biological Chemistry. 248, 22, p. 7819-7825 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
Open Access
269 Scopus citations

Genetic aspects of hyperlipidemia in coronary heart disease

Goldstein, J. L., Jan 1 1973, In : Hospital Practice. 8, 10, p. 53-65 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Homocystinuria: heterozygote detection using phytohemagglutinin-stimulated lymphocytes.

Goldstein, J. L., Campbell, B. K. & Gartler, S. M., Jan 1973, In : The Journal of clinical investigation. 52, 1, p. 218-221 4 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction

Goldstein, J. L., Hazzard, W. R., Schrott, H. G., Bierman, E. L. & Motulsky, A. G., 1973, In : Unknown Journal. 52, 7, p. 1533-1543 11 p.

Research output: Contribution to journalArticle

Open Access
424 Scopus citations

Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia

Goldstein, J. L., Schrott, H. G., Hazzard, W. R., Bierman, E. L. & Motulsky, A. G., Jan 1 1973, In : Unknown Journal. 52, 7, p. 1544-1568 25 p.

Research output: Contribution to journalArticle

Open Access
1037 Scopus citations

Hyperlipidemia in coronary heart disease. III. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction

Hazzard, W. R., Goldstein, J. L., Schrott, H. G., Motulsky, A. G. & Bierman, E. L., Jan 1 1973, In : Unknown Journal. 52, 7, p. 1569-1577 9 p.

Research output: Contribution to journalArticle

Open Access
78 Scopus citations

Phosvitin kinase from the liver of the rooster. Purification and partial characterization

Goldstein, J. L. & Hasty, M. A., Dec 1 1973, In : Journal of Biological Chemistry. 248, 18, p. 6300-6307 8 p.

Research output: Contribution to journalArticle

38 Scopus citations