Research Output

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Review article
2006

Protein sensors for membrane sterols

Goldstein, J. L., DeBose-Boyd, R. A. & Brown, M. S., Jan 13 2006, In : Cell. 124, 1, p. 35-46 12 p.

Research output: Contribution to journalReview article

1047 Scopus citations

Reelin, lipoprotein receptors and synaptic plasticity

Herz, J. & Chen, Y., Nov 1 2006, In : Nature Reviews Neuroscience. 7, 11, p. 850-859 10 p.

Research output: Contribution to journalReview article

369 Scopus citations
2005

Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality

Ge, Y., Ahn, D., Stricklett, P. K., Hughes, A. K., Yanagisawa, M., Verbalis, J. G. & Kohan, D. E., May 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 5 57-5, p. F912-F920

Research output: Contribution to journalReview article

89 Scopus citations

Molecular mechanisms of lipoprotein receptor signalling

May, P., Herz, J. & Bock, H. H., Oct 1 2005, In : Cellular and Molecular Life Sciences. 62, 19-20, p. 2325-2338 14 p.

Research output: Contribution to journalReview article

109 Scopus citations
2004

A bull's eye for targeted lung cancer therapy

Minna, J. D., Gazdar, A. F., Sprang, S. R. & Herz, J., Jun 4 2004, In : Science. 304, 5676, p. 1458-1461 4 p.

Research output: Contribution to journalReview article

63 Scopus citations

Functions of lipoprotein receptors in neurons

Beffert, U., Stolt, P. C. & Herz, J., Mar 1 2004, In : Journal of lipid research. 45, 3, p. 403-409 7 p.

Research output: Contribution to journalReview article

111 Scopus citations

Knowing when to let go: Endosomal release of LDL from the LDL-receptor

DeBose-Boyd, R. A., Oct 22 2004, In : Molecular cell. 16, 2, p. 160-162 3 p.

Research output: Contribution to journalReview article

1 Scopus citations

Lipoprotein receptors in the vascular wall

Herz, J. & Hui, D. Y., Apr 1 2004, In : Current Opinion in Lipidology. 15, 2, p. 175-181 7 p.

Research output: Contribution to journalReview article

27 Scopus citations

Molecular mediators of hepatic steatosis and liver injury

Browning, J. D. & Horton, J. D., Jul 1 2004, In : Journal of Clinical Investigation. 114, 2, p. 147-152 6 p.

Research output: Contribution to journalReview article

1542 Scopus citations
2003

Condensed complexes of cholesterol and phospholipids

McConnell, H. M. & Radhakrishnan, A., Mar 10 2003, In : Biochimica et Biophysica Acta - Biomembranes. 1610, 2, p. 159-173 15 p.

Research output: Contribution to journalReview article

321 Scopus citations

Developmental regulation of gap junctions and their role in mammary epithelial cell differentiation

El-Sabban, M. E., Abi-Mosleh, L. F. & Talhouk, R. S., Oct 1 2003, In : Journal of mammary gland biology and neoplasia. 8, 4, p. 463-473 11 p.

Research output: Contribution to journalReview article

39 Scopus citations

Gallstone Disease and Its Complications

Browning, J. D. & Horton, J. D., Oct 2003, In : Seminars in Gastrointestinal Disease. 14, 4, p. 165-177 13 p.

Research output: Contribution to journalReview article

28 Scopus citations

Integration of endocytosis and signal transduction by lipoprotein receptors.

May, P., Bock, H. H. & Herz, J., Apr 1 2003, In : Science's STKE : signal transduction knowledge environment. 2003, 176, p. PE12

Research output: Contribution to journalReview article

42 Scopus citations

LDL receptor-related proteins in neurodevelopment

May, P. & Herz, J., May 1 2003, In : Traffic. 4, 5, p. 291-301 11 p.

Research output: Contribution to journalReview article

46 Scopus citations

LRP: A bright beacon at the blood-brain barrier

Herz, J., Nov 2003, In : Journal of Clinical Investigation. 112, 10, p. 1483-1485 3 p.

Research output: Contribution to journalReview article

Open Access
52 Scopus citations

Molecular mechanisms of autosomal recessive hypercholesterolemia

Cohen, J. C., Kimmel, M., Polanski, A. & Hobbs, H. H., Apr 1 2003, In : Current opinion in lipidology. 14, 2, p. 121-127 7 p.

Research output: Contribution to journalReview article

48 Scopus citations

Monogenic hypercholesterolemia: New insights in pathogenesis and treatment

Rader, D. J., Cohen, J. & Hobbs, H. H., Jun 1 2003, In : Journal of Clinical Investigation. 111, 12, p. 1795-1803 9 p.

Research output: Contribution to journalReview article

425 Scopus citations

Mouse models as tools for dissecting disorders of lipoprotein metabolism

Marschang, P. & Herz, J., Feb 2003, In : Seminars in Cell and Developmental Biology. 14, 1, p. 25-35 11 p.

Research output: Contribution to journalReview article

4 Scopus citations

Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics

Kitamura, T., Koshino, Y., Shibata, F., Oki, T., Nakajima, H., Nosaka, T. & Kumagai, H., Nov 2003, In : Experimental Hematology. 31, 11, p. 1007-1014 8 p.

Research output: Contribution to journalReview article

548 Scopus citations

The enzymes, regulation, and genetics of bile acid synthesis

Russell, D. W., Aug 11 2003, In : Annual review of biochemistry. 72, p. 137-174 38 p.

Research output: Contribution to journalReview article

1053 Scopus citations
2002

Clinical importance of the cytochromes P450

Nebert, D. W. & Russell, D. W., Oct 12 2002, In : Lancet. 360, 9340, p. 1155-1162 8 p.

Research output: Contribution to journalReview article

964 Scopus citations

Lipoprotein receptors in the nervous system

Herz, J. & Bock, H. H., Aug 1 2002, In : Annual review of biochemistry. 71, p. 405-434 30 p.

Research output: Contribution to journalReview article

324 Scopus citations

Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)

Hofmann, S. L., Atashband, A., Cho, S. K., Das, A. K., Gupta, P. & Lu, J. Y., Jul 23 2002, In : Current molecular medicine. 2, 5, p. 423-437 15 p.

Research output: Contribution to journalReview article

28 Scopus citations

Orexins: From neuropeptides to energy homeostasis and sleep/wake regulation

Beuckmann, C. T. & Yanagisawa, M., Jul 25 2002, In : Journal of Molecular Medicine. 80, 6, p. 329-342 14 p.

Research output: Contribution to journalReview article

121 Scopus citations

Sleep, feeding, and neuropeptides: Roles of orexins and orexin receptors

Mieda, M. & Yanagisawa, M., Jun 1 2002, In : Current Opinion in Neurobiology. 12, 3, p. 339-345 7 p.

Research output: Contribution to journalReview article

86 Scopus citations
Open Access
3139 Scopus citations
2001

Endothelin system: The double-edged sword in health and disease

Kedzierski, R. M. & Yanagisawa, M., May 10 2001, In : Annual Review of Pharmacology and Toxicology. 41, p. 851-876 26 p.

Research output: Contribution to journalReview article

574 Scopus citations

Lipoprotein receptors: Beacons to neurons?

Herz, J., Apr 1 2001, In : Trends in Neurosciences. 24, 4, p. 193-195 3 p.

Research output: Contribution to journalReview article

17 Scopus citations

LRP: A multifunctional scavenger and signaling receptor

Herz, J. & Strickland, D. K., Oct 1 2001, In : Journal of Clinical Investigation. 108, 6, p. 779-784 6 p.

Research output: Contribution to journalReview article

799 Scopus citations

New mutations in the neuronal ceroid lipofuscinosis genes

Mole, S. E., Zhong, N. A., Sarpong, A., Logan, W. P., Hofmann, S., Yi, W., Franken, P. F., Van Diggelen, O. P., Breuning, M. H., Moroziewicz, D., Ju, W., Salonen, T., Holmberg, V., Järvelä, I. & Taschner, P. E. M., 2001, In : European Journal of Paediatric Neurology. 5, SUPPL. A, p. 7-10 4 p.

Research output: Contribution to journalReview article

23 Scopus citations

The LDL receptor gene family: Signaling functions during development

Howell, B. W. & Herz, J., Jan 1 2001, In : Current Opinion in Neurobiology. 11, 1, p. 74-81 8 p.

Research output: Contribution to journalReview article

66 Scopus citations

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

Willie, J. T., Chemelli, R. M., Sinton, C. M. & Yanagisawa, M., Aug 11 2001, In : Annual Review of Neuroscience. 24, p. 429-458 30 p.

Research output: Contribution to journalReview article

613 Scopus citations
2000

Cellular signalling by lipoprotein receptors

Herz, J., Gotthardt, M. & Willnow, T. E., May 4 2000, In : Current Opinion in Lipidology. 11, 2, p. 161-166 6 p.

Research output: Contribution to journalReview article

63 Scopus citations

Oxysterol biosynthetic enzymes

Russell, D. W., Dec 15 2000, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1529, 1-3, p. 126-135 10 p.

Research output: Contribution to journalReview article

274 Scopus citations

Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans

Brown, M. S., Ye, J., Rawson, R. B. & Goldstein, J. L., Feb 18 2000, In : Cell. 100, 4, p. 391-398 8 p.

Research output: Contribution to journalReview article

Open Access
1067 Scopus citations

Renal tubular effects of endothelin-B receptor signaling: Its role in cardiovascular homeostasis and extracellular volume regulation

Ohuchi, T., Yanagisawa, M. & Gariepy, C. E., Jul 24 2000, In : Current opinion in nephrology and hypertension. 9, 4, p. 435-439 5 p.

Research output: Contribution to journalReview article

27 Scopus citations
1999
2 Scopus citations

Lipoprotein(a): Intrigues and insights

Hobbs, H. H. & White, A. L., Sep 6 1999, In : Current Opinion in Lipidology. 10, 3, p. 225-236 12 p.

Research output: Contribution to journalReview article

158 Scopus citations

Lipoprotein receptors: New roles for ancient proteins

Willnow, T. E., Nykjaer, A. & Herz, J., Oct 1999, In : Nature cell biology. 1, 6, p. E157-E162

Research output: Contribution to journalReview article

172 Scopus citations
2 Scopus citations

Nuclear orphan receptors control cholesterol catabolism

Russell, D. W., May 28 1999, In : Cell. 97, 5, p. 539-542 4 p.

Research output: Contribution to journalReview article

182 Scopus citations

Sterol regulatory element-binding proteins: Activators of cholesterol and fatty acid biosynthesis

Horton, J. D. & Shimomura, L., Apr 1999, In : Current opinion in lipidology. 10, 2, p. 143-150 8 p.

Research output: Contribution to journalReview article

256 Scopus citations
1998

Cholesterol metabolism and embryogenesis

Farese, R. V. & Herz, J., Mar 1 1998, In : Trends in Genetics. 14, 3, p. 115-120 6 p.

Research output: Contribution to journalReview article

104 Scopus citations

Two 7α-hydroxylase enzymes in bile acid biosynthesis

Schwarz, M., Lund, E. G. & Russell, D. W., Apr 21 1998, In : Current Opinion in Lipidology. 9, 2, p. 113-118 6 p.

Research output: Contribution to journalReview article

83 Scopus citations
1997

The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

Brown, M. S. & Goldstein, J. L., May 2 1997, In : Cell. 89, 3, p. 331-340 10 p.

Research output: Contribution to journalReview article

2651 Scopus citations
1996

Male pseudohermaphroditism due to steroid 5α-reductase 2 deficiency: Diagnosis, psychological evaluation, and management

Mendonca, B. B., Inacio, M., Costa, E. M. F., Arnhold, I. J. P., Silva, F. A. Q., Nicolau, W., Bloise, W., Russell, D. W. & Wilson, J. D., Mar 1 1996, In : Medicine. 75, 2, p. 64-76 13 p.

Research output: Contribution to journalReview article

100 Scopus citations
1995

Animal models for disorders of hepatic lipoprotein metabolism

Willnow, T. E. & Herz, J., May 1 1995, In : Journal of Molecular Medicine. 73, 5, p. 213-220 8 p.

Research output: Contribution to journalReview article

5 Scopus citations

Lipoprotein and receptor interactions in vivo

Herz, J. & Willnow, T. E., Jan 1 1995, In : Current Opinion in Lipidology. 6, 2, p. 97-103 7 p.

Research output: Contribution to journalReview article

85 Scopus citations
1994

Molecular genetics of lipoprotein (a): New pieces to the puzzle

Gaw, A. & Hobbs, H., Jan 1 1994, In : Current opinion in lipidology. 5, 2, p. 149-155 7 p.

Research output: Contribution to journalReview article

47 Scopus citations

Steroid 5α-reductase: Two genes/two enzymes

Russell, D. W. & Wilson, J. D., Jan 1 1994, In : Annual review of biochemistry. 63, p. 25-61 37 p.

Research output: Contribution to journalReview article

933 Scopus citations