Research Output

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Review article
2001

LRP: A multifunctional scavenger and signaling receptor

Herz, J. & Strickland, D. K., 2001, In : Journal of Clinical Investigation. 108, 6, p. 779-784 6 p.

Research output: Contribution to journalReview article

802 Scopus citations

New mutations in the neuronal ceroid lipofuscinosis genes

Mole, S. E., Zhong, N. A., Sarpong, A., Logan, W. P., Hofmann, S., Yi, W., Franken, P. F., Van Diggelen, O. P., Breuning, M. H., Moroziewicz, D., Ju, W., Salonen, T., Holmberg, V., Järvelä, I. & Taschner, P. E. M., 2001, In : European Journal of Paediatric Neurology. 5, SUPPL. A, p. 7-10 4 p.

Research output: Contribution to journalReview article

23 Scopus citations

The LDL receptor gene family: Signaling functions during development

Howell, B. W. & Herz, J., 2001, In : Current Opinion in Neurobiology. 11, 1, p. 74-81 8 p.

Research output: Contribution to journalReview article

66 Scopus citations

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

Willie, J. T., Chemelli, R. M., Sinton, C. M. & Yanagisawa, M., Aug 11 2001, In : Annual Review of Neuroscience. 24, p. 429-458 30 p.

Research output: Contribution to journalReview article

613 Scopus citations
2002

Clinical importance of the cytochromes P450

Nebert, D. W. & Russell, D. W., Oct 12 2002, In : Lancet. 360, 9340, p. 1155-1162 8 p.

Research output: Contribution to journalReview article

968 Scopus citations

Lipoprotein receptors in the nervous system

Herz, J. & Bock, H. H., 2002, In : Annual review of biochemistry. 71, p. 405-434 30 p.

Research output: Contribution to journalReview article

326 Scopus citations

Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)

Hofmann, S. L., Atashband, A., Cho, S. K., Das, A. K., Gupta, P. & Lu, J. Y., 2002, In : Current molecular medicine. 2, 5, p. 423-437 15 p.

Research output: Contribution to journalReview article

28 Scopus citations

Orexins: From neuropeptides to energy homeostasis and sleep/wake regulation

Beuckmann, C. T. & Yanagisawa, M., Jul 25 2002, In : Journal of Molecular Medicine. 80, 6, p. 329-342 14 p.

Research output: Contribution to journalReview article

122 Scopus citations

Sleep, feeding, and neuropeptides: Roles of orexins and orexin receptors

Mieda, M. & Yanagisawa, M., Jun 1 2002, In : Current Opinion in Neurobiology. 12, 3, p. 339-345 7 p.

Research output: Contribution to journalReview article

86 Scopus citations
Open Access
3171 Scopus citations
2003

Condensed complexes of cholesterol and phospholipids

McConnell, H. M. & Radhakrishnan, A., Mar 10 2003, In : Biochimica et Biophysica Acta - Biomembranes. 1610, 2, p. 159-173 15 p.

Research output: Contribution to journalReview article

322 Scopus citations

Developmental regulation of gap junctions and their role in mammary epithelial cell differentiation

El-Sabban, M. E., Abi-Mosleh, L. F. & Talhouk, R. S., Oct 1 2003, In : Journal of mammary gland biology and neoplasia. 8, 4, p. 463-473 11 p.

Research output: Contribution to journalReview article

39 Scopus citations

Gallstone Disease and Its Complications

Browning, J. D. & Horton, J. D., Oct 2003, In : Seminars in Gastrointestinal Disease. 14, 4, p. 165-177 13 p.

Research output: Contribution to journalReview article

28 Scopus citations

Integration of endocytosis and signal transduction by lipoprotein receptors.

May, P., Bock, H. H. & Herz, J., Apr 1 2003, In : Science's STKE : signal transduction knowledge environment. 2003, 176, p. PE12

Research output: Contribution to journalReview article

42 Scopus citations

LDL receptor-related proteins in neurodevelopment

May, P. & Herz, J., May 1 2003, In : Traffic. 4, 5, p. 291-301 11 p.

Research output: Contribution to journalReview article

46 Scopus citations

LRP: A bright beacon at the blood-brain barrier

Herz, J., Nov 2003, In : Journal of Clinical Investigation. 112, 10, p. 1483-1485 3 p.

Research output: Contribution to journalReview article

Open Access
52 Scopus citations

Molecular mechanisms of autosomal recessive hypercholesterolemia

Cohen, J. C., Kimmel, M., Polanski, A. & Hobbs, H. H., Apr 2003, In : Current opinion in lipidology. 14, 2, p. 121-127 7 p.

Research output: Contribution to journalReview article

48 Scopus citations

Monogenic hypercholesterolemia: New insights in pathogenesis and treatment

Rader, D. J., Cohen, J. & Hobbs, H. H., Jun 2003, In : Journal of Clinical Investigation. 111, 12, p. 1795-1803 9 p.

Research output: Contribution to journalReview article

427 Scopus citations

Mouse models as tools for dissecting disorders of lipoprotein metabolism

Marschang, P. & Herz, J., Feb 2003, In : Seminars in Cell and Developmental Biology. 14, 1, p. 25-35 11 p.

Research output: Contribution to journalReview article

4 Scopus citations

Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics

Kitamura, T., Koshino, Y., Shibata, F., Oki, T., Nakajima, H., Nosaka, T. & Kumagai, H., Nov 2003, In : Experimental Hematology. 31, 11, p. 1007-1014 8 p.

Research output: Contribution to journalReview article

550 Scopus citations

The enzymes, regulation, and genetics of bile acid synthesis

Russell, D. W., 2003, In : Annual review of biochemistry. 72, p. 137-174 38 p.

Research output: Contribution to journalReview article

1069 Scopus citations
2004

A bull's eye for targeted lung cancer therapy

Minna, J. D., Gazdar, A. F., Sprang, S. R. & Herz, J., Jun 4 2004, In : Science. 304, 5676, p. 1458-1461 4 p.

Research output: Contribution to journalReview article

63 Scopus citations

Functions of lipoprotein receptors in neurons

Beffert, U., Stolt, P. C. & Herz, J., Mar 2004, In : Journal of lipid research. 45, 3, p. 403-409 7 p.

Research output: Contribution to journalReview article

112 Scopus citations

Knowing when to let go: Endosomal release of LDL from the LDL-receptor

DeBose-Boyd, R. A., Oct 22 2004, In : Molecular cell. 16, 2, p. 160-162 3 p.

Research output: Contribution to journalReview article

1 Scopus citations

Lipoprotein receptors in the vascular wall

Herz, J. & Hui, D. Y., Apr 2004, In : Current opinion in lipidology. 15, 2, p. 175-181 7 p.

Research output: Contribution to journalReview article

27 Scopus citations

Molecular mediators of hepatic steatosis and liver injury

Browning, J. D. & Horton, J. D., Jul 2004, In : Journal of Clinical Investigation. 114, 2, p. 147-152 6 p.

Research output: Contribution to journalReview article

1551 Scopus citations
2005

Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality

Ge, Y., Ahn, D., Stricklett, P. K., Hughes, A. K., Yanagisawa, M., Verbalis, J. G. & Kohan, D. E., May 2005, In : American Journal of Physiology - Renal Physiology. 288, 5 57-5, p. F912-F920

Research output: Contribution to journalReview article

89 Scopus citations

Molecular mechanisms of lipoprotein receptor signalling

May, P., Herz, J. & Bock, H. H., Oct 2005, In : Cellular and Molecular Life Sciences. 62, 19-20, p. 2325-2338 14 p.

Research output: Contribution to journalReview article

109 Scopus citations
2006

Functional biology of the neuronal ceroid lipofuscinoses (NCL) proteins

Kyttälä, A., Lahtinen, U., Braulke, T. & Hofmann, S. L., Oct 1 2006, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1762, 10, p. 920-933 14 p.

Research output: Contribution to journalReview article

69 Scopus citations

Lowering LDL - Not only how low, but how long?

Brown, M. S. & Goldstein, J. L., Mar 24 2006, In : Science. 311, 5768, p. 1721-1723 3 p.

Research output: Contribution to journalReview article

158 Scopus citations

Lysosomal metabolism of lipid-modified proteins

Lu, J. Y. & Hofmann, S. L., 2006, In : Journal of lipid research. 47, 7, p. 1352-1357 6 p.

Research output: Contribution to journalReview article

43 Scopus citations

Protein sensors for membrane sterols

Goldstein, J. L., DeBose-Boyd, R. A. & Brown, M. S., Jan 13 2006, In : Cell. 124, 1, p. 35-46 12 p.

Research output: Contribution to journalReview article

1060 Scopus citations

Reelin, lipoprotein receptors and synaptic plasticity

Herz, J. & Chen, Y., Nov 1 2006, In : Nature Reviews Neuroscience. 7, 11, p. 850-859 10 p.

Research output: Contribution to journalReview article

372 Scopus citations
2007

Molecular biology of PCSK9: its role in LDL metabolism

Horton, J. D., Cohen, J. C. & Hobbs, H. H., Feb 1 2007, In : Trends in Biochemical Sciences. 32, 2, p. 71-77 7 p.

Research output: Contribution to journalReview article

373 Scopus citations

Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus

Ye, J., Aug 2007, In : PLoS pathogens. 3, 8, p. 1017-1022 6 p.

Research output: Contribution to journalReview article

112 Scopus citations
2008

Endothelin: 20 Years from discovery to therapy

Barton, M. & Yanagisawa, M., Aug 1 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 8, p. 485-498 14 p.

Research output: Contribution to journalReview article

213 Scopus citations
2009

Apolipoprotein E receptors in the nervous system

Herz, J., Jun 2009, In : Current opinion in lipidology. 20, 3, p. 190-196 7 p.

Research output: Contribution to journalReview article

53 Scopus citations

Cholesterol 24-hydroxylase: An enzyme of cholesterol turnover in the brain

Russell, D. W., Halford, R. W., Ramirez, D. M. O., Shah, R. & Kotti, T., 2009, In : Annual review of biochemistry. 78, p. 1017-1040 24 p.

Research output: Contribution to journalReview article

154 Scopus citations

Cholesterol feedback: From Schoenheimer's bottle to Scap's MELADL

Brown, M. S. & Goldstein, J. L., Apr 2009, In : Journal of lipid research. 50, SUPPL., p. S15-S27

Research output: Contribution to journalReview article

307 Scopus citations

Expanding functions of lipoprotein receptors

Herz, J., Chen, Y., Masiulis, I. & Zhou, L., Apr 2009, In : Journal of lipid research. 50, SUPPL., p. S287-S292

Research output: Contribution to journalReview article

53 Scopus citations

Fifty years of advances in bile acid synthesis and metabolism

Russell, D. W., Apr 2009, In : Journal of lipid research. 50, SUPPL., p. S120-S125

Research output: Contribution to journalReview article

188 Scopus citations

PCSK9: A convertase that coordinates LDL catabolism

Horton, J. D., Cohen, J. C. & Hobbs, H. H., Apr 2009, In : Journal of lipid research. 50, SUPPL., p. S172-S177

Research output: Contribution to journalReview article

380 Scopus citations

The LDL receptor

Goldstein, J. L. & Brown, M. S., Apr 1 2009, In : Arteriosclerosis, thrombosis, and vascular biology. 29, 4, p. 431-438 8 p.

Research output: Contribution to journalReview article

655 Scopus citations
2010
98 Scopus citations

Emerging topics in Reelin function

Förster, E., Bock, H. H., Herz, J., Chai, X., Frotscher, M. & Zhao, S., May 2010, In : European Journal of Neuroscience. 31, 9, p. 1511-1518 8 p.

Research output: Contribution to journalReview article

95 Scopus citations

Lipoprotein receptors-an evolutionarily ancient multifunctional receptor family

Dieckmann, M., Dietrich, M. F. & Herz, J., Nov 1 2010, In : Biological Chemistry. 391, 11, p. 1341-1363 23 p.

Research output: Contribution to journalReview article

65 Scopus citations

Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis

Ohazama, A., Porntaveetus, T., Ota, M. S., Herz, J. & Sharpe, P. T., Dec 2010, In : American Journal of Medical Genetics, Part A. 152 A, 12, p. 2974-2983 10 p.

Research output: Contribution to journalReview article

21 Scopus citations
2011

Human fatty liver disease: Old questions and new insights

Cohen, J. C., Horton, J. D. & Hobbs, H. H., Jun 24 2011, In : Science. 332, 6037, p. 1519-1523 5 p.

Research output: Contribution to journalReview article

1261 Scopus citations

Regulation of cholesterol and fatty acid synthesis

Ye, J. & DeBose-Boyd, R. A., Jul 2011, In : Cold Spring Harbor Perspectives in Biology. 3, 7, p. 1-13 13 p.

Research output: Contribution to journalReview article

136 Scopus citations

The card players of Caravaggio, Cézanne and Mark Twain: Tips for getting lucky in high-stakes research

Goldstein, J. L., Oct 1 2011, In : Nature medicine. 17, 10, p. 1201-1205 5 p.

Research output: Contribution to journalReview article