Neurology & Neurotherapeutics - NE Multiple Sclerosis Section

Research Output

2020

Effect of fingolimod on MRI outcomes in patients with paediatric-onset multiple sclerosis: Results from the phase 3 PARADIG MS study

Arnold, D. L., Banwell, B., Bar-Or, A., Ghezzi, A., Greenberg, B. M., Waubant, E., Giovannoni, G., Wolinsky, J. S., Gärtner, J., Rostásy, K., Krupp, L., Tardieu, M., Brück, W., Stites, T. E., Pearce, G. L., Häring, D. A., Merschhemke, M. & Chitnis, T., May 1 2020, In : Journal of Neurology, Neurosurgery and psychiatry. 91, 5, p. 483-492 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Limitations of cell-lineage-specific non-dynamic gene recombination in CD11c.Cre+ITGA4fl/fl mice

Manouchehri, N., Hussain, R. Z., Cravens, P. D., Doelger, R., Greenberg, B. M., Okuda, D. T., Forsthuber, T. G., Eagar, T. N. & Stüve, O., Jul 15 2020, In : Journal of Neuroimmunology. 344, 577245.

Research output: Contribution to journalArticle

Safety and efficacy of satralizumab monotherapy in neuromyelitis optica spectrum disorder: a randomised, double-blind, multicentre, placebo-controlled phase 3 trial

Traboulsee, A., Greenberg, B. M., Bennett, J. L., Szczechowski, L., Fox, E., Shkrobot, S., Yamamura, T., Terada, Y., Kawata, Y., Wright, P., Gianella-Borradori, A., Garren, H. & Weinshenker, B. G., May 2020, In : The Lancet Neurology. 19, 5, p. 402-412 11 p.

Research output: Contribution to journalArticle

Two cases of aquaporin-4 positive neuromyelitis optica associated with T-cell lymphoma

Blackburn, K., Wang, C. & Greenberg, B., Jan 15 2020, In : Journal of Neuroimmunology. 338, 577092.

Research output: Contribution to journalArticle

2019

Acquisition of Early Developmental Milestones and Need for Special Education Services in Pediatric Multiple Sclerosis

Aaen, G., Waltz, M., Vargas, W., Makhani, N., Ness, J., Harris, Y., Casper, T. C., Benson, L., Candee, M., Chitnis, T., Gorman, M., Graves, J., Greenberg, B., Lotze, T., Mar, S., Tillema, J. M., Rensel, M., Rodriguez, M., Rose, J., Rubin, J. & 6 others, Schreiner, T., Waldman, A., Weinstock-Guttman, B., Belman, A., Waubant, E. & Krupp, L., Mar 1 2019, In : Journal of child neurology. 34, 3, p. 148-152 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Acute vestibular migraine treatment with noninvasive vagus nerve stimulation

Beh, S. C. & Friedman, D. I., Oct 29 2019, In : Neurology. 93, 18, p. e1715-e1719

Research output: Contribution to journalArticle

Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry

Chi, C., Shao, X., Rhead, B., Gonzales, E., Smith, J. B., Xiang, A. H., Graves, J., Waldman, A., Lotze, T., Schreiner, T., Weinstock-Guttman, B., Aaen, G., Tillema, J. M., Ness, J., Candee, M., Krupp, L., Gorman, M., Benson, L., Chitnis, T., Mar, S. & 13 others, Belman, A., Casper, T. C., Rose, J., Moodley, M., Rensel, M., Rodriguez, M., Greenberg, B., Kahn, L., Rubin, J., Schaefer, C., Waubant, E., Langer-Gould, A. & Barcellos, L. F., Jan 1 2019, In : PLoS genetics. 15, 1, e1007808.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study

Steyerberg, E. W., Wiegers, E., Sewalt, C., Buki, A., Citerio, G., De Keyser, V., Ercole, A., Kunzmann, K., Lanyon, L., Lecky, F., Lingsma, H., Manley, G., Nelson, D., Peul, W., Stocchetti, N., von Steinbüchel, N., Vande Vyvere, T., Verheyden, J., Wilson, L., Maas, A. I. R. & 230 others, Menon, D. K., Ackerlund, C., Amrein, K., Andelic, N., Andreassen, L., Anke, A., Antoni, A., Audibert, G., Auslands, K., Azouvi, P., Azzolini, M. L., Badenes, R., Bartels, R., Barzó, P., Beauvais, R., Beer, R., Bellander, B. M., Belli, A., Benali, H., Berardino, M., Beretta, L., Blaabjerg, M., Bragge, P., Brazinova, A., Brinck, V., Brooker, J., Brorsson, C., Bullinger, M., Cabeleira, M., Caccioppola, A., Calappi, E., Calvi, M. R., Cameron, P., Carbayo Lozano, G., Carbonara, M., Castaño-León, A. M., Chevallard, G., Chieregato, A., Cnossen, M., Coburn, M., Coles, J., Cooper, J. D., Correia, M., Čović, A., Curry, N., Czeiter, E., Czosnyka, M., Dahyot-Fizelier, C., Dawes, H., Degos, V., Della Corte, F., den Boogert, H., Depreitere, B., Dijkland, S., Đilvesi, Đ., Dixit, A., Donoghue, E., Dreier, J., Dulière, G. L., Esser, P., Ezer, E., Fabricius, M., Feigin, V. L., Foks, K., Frisvold, S., Furmanov, A., Gagliardo, P., Galanaud, D., Gantner, D., Gao, G., George, P., Ghuysen, A., Giga, L., Glocker, B., Golubović, J., Gomez, P. A., Gratz, J., Gravesteijn, B., Grossi, F., Gruen, R. L., Gupta, D., Haagsma, J. A., Haitsma, I., Helbok, R., Helseth, E., Horton, L., Huijben, J., Hutchinson, P. J., Jacobs, B., Jankowski, S., Jarrett, M., Jiang, J. Y., Jones, K., Karan, M., Kolias, A. G., Kompanje, E., Kondziella, D., Koraropoulos, E., Koskinen, L. O., Kovács, N., Lagares, A., Laureys, S., Lefering, R., Legrand, V., Lejeune, A., Levi, L., Lightfoot, R., Lozano, A., Maegele, M., Majdan, M., Manara, A., Maréchal, H., Martino, C., Mattern, J., McMahon, C., Melegh, B., Menovsky, T., Mulazzi, D., Muraleedharan, V., Murray, L., Nair, N., Negru, A., Newcombe, V., Nieboer, D., Noirhomme, Q., Nyirádi, J., Oddo, M., Oresic, M., Ortolano, F., Otesile, O., Palotie, A., Parizel, P. M., Payen, J. F., Perera, N., Perlbarg, V., Persona, P., Piippo-Karjalainen, A., Pili Floury, S., Pirinen, M., Ples, H., Polinder, S., Pomposo, I., Posti, J. P., Puybasset, L., Rădoi, A., Ragauskas, A., Raj, R., Rambadagalla, M., Real, R., Rhodes, J., Richardson, S., Richter, S., Ripatti, S., Rocka, S., Roe, C., Roise, O., Rosand, J., Rosenfeld, J. V., Rosenlund, C., Rosenthal, G., Rossaint, R., Rossi, S., Rueckert, D., Rusnák, M., Sahuquillo, J., Sakowitz, O., Sanchez-Porras, R., Sandor, J., Schäfer, N., Schmidt, S., Schoechl, H., Schoonman, G., Schou, R. F., Schwendenwein, E., Skandsen, T., Smielewski, P., Sorinola, A., Stamatakis, E., Stanworth, S., Stevanovic, A., Stevens, R., Stewart, W., Sundström, N., Synnot, A., Takala, R., Tamás, V., Tamosuitis, T., Taylor, M. S., Te Ao, B., Tenovuo, O., Theadom, A., Thomas, M., Tibboel, D., Timmers, M., Tolias, C., Trapani, T., Tudora, C. M., Vajkoczy, P., Valeinis, E., Vallance, S., Vámos, Z., van der Naalt, J., Van der Steen, G., van Dijck, J. T. J. M., van Essen, T. A., Van Hecke, W., van Heugten, C., Van Praag, D., van Wijk, R. P. J., Vanhaudenhuyse, A., Vargiolu, A., Vega, E., Velt, K., Vespa, P. M., Vik, A., Vilcinis, R., Volovici, V., Voormolen, D., Vulekovic, P., Wang, K. K. W., Williams, G., Winzeck, S., Wolf, S., Yang, Z., Ylén, P., Younsi, A., Zeiler, F. A., Zelinkova, V., Ziverte, A. & Zoerle, T., Oct 2019, In : The Lancet Neurology. 18, 10, p. 923-934 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Cataclysmically disseminating neurologic presentation in an immunosuppressed lupus patient: From the National Multiple Sclerosis Society Case Conference Proceedings

Perrone, C. M., Lisak, R. P., Meltzer, E. I., Sguigna, P., Tizazu, E., Jacobs, D., Melamed, E., Lucas, A., Freeman, L., Pardo, G., Goodman, A., Fox, E. J., Costello, K., Parsons, M. S., Zamvil, S. S., Frohman, E. M. & Frohman, T. C., Jul 1 2019, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 4, e582.

Research output: Contribution to journalReview article

Open Access

Cerebellar volume loss in radiologically isolated syndrome

George, I. C., El Mendili, M. M., Inglese, M., Azevedo, C. J., Kantarci, O., Lebrun, C., Siva, A., Okuda, D. T. & Pelletier, D., Jan 1 2019, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

Core temperature is not elevated at rest in people with relapsing-remitting multiple sclerosis

Chaseling, G. K., Allen, D. R., Vucic, S., Barnett, M., Frohman, E., Davis, S. L. & Jay, O., Apr 1 2019, In : Multiple Sclerosis and Related Disorders. 29, p. 62-67 6 p.

Research output: Contribution to journalArticle

Correction to: Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study (Acta Neurochirurgica, (2019), 161, 3, (435-449), 10.1007/s00701-018-3761-z)

on behalf of the CENTER-TBI Investigators and Participants, Mar 13 2019, In : Acta Neurochirurgica. 161, 3, p. 451-455 5 p.

Research output: Contribution to journalComment/debate

Impaired Thermoregulatory Function during Dynamic Exercise in Multiple Sclerosis

Allen, D. R., Huang, M., Morris, N. B., Chaseling, G. K., Frohman, E., Jay, O. & Davis, S. L., Mar 1 2019, In : Medicine and science in sports and exercise. 51, 3, p. 395-404 10 p.

Research output: Contribution to journalArticle

miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS

the US Network of Pediatric MS Centers, Jun 1 2019, In : Annals of Clinical and Translational Neurology. 6, 6, p. 1053-1061 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

New onset transverse myelitis diagnostic accuracy and patient experiences

Greenberg, B., Krishnan, C. & Harder, L. L., May 1 2019, In : Multiple Sclerosis and Related Disorders. 30, p. 42-44 3 p.

Research output: Contribution to journalArticle

Preserved canonicality of the BOLD hemodynamic response reflects healthy cognition: Insights into the healthy brain through the window of Multiple Sclerosis

Turner, M. P., Hubbard, N. A., Sivakolundu, D. K., Himes, L. M., Hutchison, J. L., Hart, J., Spence, J. S., Frohman, E., Frohman, T. C., Okuda, D. & Rypma, B., Apr 15 2019, In : NeuroImage. 190, p. 46-55 10 p.

Research output: Contribution to journalReview article

6 Scopus citations

Reduced arterial compliance along the cerebrovascular tree predicts cognitive slowing in multiple sclerosis: Evidence for a neurovascular uncoupling hypothesis

Sivakolundu, D. K., West, K. L., Maruthy, G. B., Zuppichini, M., Turner, M. P., Abdelkarim, D., Zhao, Y., Nguyen, D., Spence, J. S., Lu, H., Okuda, D. & Rypma, B., Jan 1 2019, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

1 Scopus citations
2 Scopus citations

Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders

International Conference on Spinal Cord Involvement and Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders, Feb 1 2019, In : The Lancet Neurology. 18, 2, p. 185-197 13 p.

Research output: Contribution to journalReview article

17 Scopus citations

T and B cell subsets differentially correlate with amyloid deposition and neurocognitive function in patients with amnestic mild cognitive impairment after one year of physical activity

Poinsatte, K., Smith, E. E., Torres, V. O., Ortega, S. B., Huebinger, R. M., Cullum, C. M., Monson, N. L., Zhang, R. & Stowe, A. M., Jan 1 2019, In : Exercise immunology review. 25, p. 34-49 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings

Beh, S. C., Masrour, S., Smith, S. V. & Friedman, D. I., Jan 1 2019, In : Headache.

Research output: Contribution to journalArticle

10 Scopus citations

The “eye of the tiger” in a patient with multiple sclerosis

Beh, S. C., Apr 15 2019, In : Journal of the Neurological Sciences. 399, p. 1-2 2 p.

Research output: Contribution to journalLetter

Three-Dimensional Lesion Phenotyping and Physiologic Characterization Inform Remyelination Ability in Multiple Sclerosis

Sivakolundu, D. K., Hansen, M. R., West, K. L., Wang, Y., Stanley, T., Wilson, A., McCreary, M., Turner, M. P., Pinho, M. C., Newton, B. D., Guo, X., Rypma, B. & Okuda, D. T., Jan 1 2019, In : Journal of Neuroimaging.

Research output: Contribution to journalArticle

1 Scopus citations

Trial of satralizumab in neuromyelitis optica spectrum disorder

Yamamura, T., Kleiter, I., Fujihara, K., Palace, J., Greenberg, B., Zakrzewska-Pniewska, B., Patti, F., Tsai, C. P., Saiz, A., Yamazaki, H., Kawata, Y., Wright, P. & De Seze, J., Nov 28 2019, In : New England Journal of Medicine. 381, 22, p. 2114-2124 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations

Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study

on behalf of the CENTER-TBI Investigators and Participants, Mar 13 2019, In : Acta Neurochirurgica. 161, 3, p. 435-449 15 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2 Scopus citations

Vitamin D genes influence MS relapses in children

Graves, J. S., Barcellos, L. F., Krupp, L., Belman, A., Shao, X., Quach, H., Hart, J., Chitnis, T., Weinstock-Guttman, B., Aaen, G., Benson, L., Gorman, M., Greenberg, B., Lotze, T., Soe, M., Ness, J., Rodriguez, M., Rose, J., Schreiner, T., Tillema, J. M. & 3 others, Waldman, A., Casper, T. C. & Waubant, E., Jan 1 2019, In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

3 Scopus citations

α4-integrin deficiency in B cells does not affect disease in a T-cell-mediated EAE disease model

Hussain, R. Z., Cravens, P. D., Miller-Little, W. A., Doelger, R., Granados, V., Herndon, E., Okuda, D. T., Eagar, T. N. & Stüve, O., Jul 1 2019, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 4, e563.

Research output: Contribution to journalArticle

Open Access
2018

A Case of Vestibular Migraine Resolving on Warfarin and Topiramate

Beh, S. C., Apr 1 2018, In : Headache. 58, 4, p. 599-600 2 p.

Research output: Contribution to journalArticle

Acute management of optic neuritis: An evolving paradigm

Horton, L. & Bennett, J. L., Jan 1 2018, In : Journal of Neuro-Ophthalmology. 38, 3, p. 358-367 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Analysis of Agreement of Retinal-Layer Thickness Measures Derived from the Segmentation of Horizontal and Vertical Spectralis OCT Macular Scans

Gonzalez Caldito, N., Antony, B., He, Y., Lang, A., Nguyen, J., Rothman, A., Ogbuokiri, E., Avornu, A., Balcer, L., Frohman, E., Frohman, T. C., Bhargava, P., Prince, J., Calabresi, P. A. & Saidha, S., Mar 4 2018, In : Current Eye Research. 43, 3, p. 415-423 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Anomalies Characteristic of Central Nervous System Demyelination: Radiologically Isolated Syndrome

RISConsortium, Feb 1 2018, In : Neurologic Clinics. 36, 1, p. 59-68 10 p.

Research output: Contribution to journalReview article

4 Scopus citations
6 Scopus citations

Aquaporin-4 serostatus does not predict response to immunotherapy in neuromyelitis optica spectrum disorders

Mealy, M. A., Kim, S. H., Schmidt, F., López, R., Jimenez Arango, J. A., Paul, F., Wingerchuk, D. M., Greenberg, B. M., Kim, H. J. & Levy, M., Nov 1 2018, In : Multiple Sclerosis Journal. 24, 13, p. 1737-1742 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Area postrema syndrome: Frequency, criteria, and severity in AQP4-IgG-positive NMOSD

Shosha, E., Dubey, D., Palace, J., Nakashima, I., Jacob, A., Fujihara, K., Takahashi, T., Whittam, D., Leite, M. I., Misu, T., Yoshiki, T., Messina, S., Elsone, L., Majed, M., Flanagan, E., Gadoth, A., Huebert, C., Sagen, J., Greenberg, B., Levy, M. & 3 others, Banerjee, A., Weinshenker, B. & Pittock, S. J., Oct 23 2018, In : Neurology. 91, 17, p. e1642-e1651

Research output: Contribution to journalArticle

21 Scopus citations

Assessment of Renal Deterioration and Associated Risk Factors in Patients With Multiple Sclerosis

Shakir, N. A., Satyanarayan, A., Eastman, J., Greenberg, B. & Lemack, G. E., Jan 1 2018, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

2 Scopus citations

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica

Estrada, K., Whelan, C. W., Zhao, F., Bronson, P., Handsaker, R. E., Sun, C., Carulli, J. P., Harris, T., Ransohoff, R. M., McCarroll, S. A., Day-Williams, A. G., Greenberg, B. M. & MacArthur, D. G., Dec 1 2018, In : Nature Communications. 9, 1, 1929.

Research output: Contribution to journalArticle

17 Scopus citations

Body mass index, but not vitamin D status, is associated with brain volume change in MS

Mowry, E. M., Azevedo, C. J., McCulloch, C. E., Okuda, D., Lincoln, R. R., Waubant, E., Hauser, S. L. & Pelletier, D., Dec 11 2018, In : Neurology. 91, 24, p. e2256-e2264

Research output: Contribution to journalArticle

17 Scopus citations

BRAF mutation leading to central nervous system rosai-dorfman disease

Richardson, T. E., Wachsmann, M., Oliver, D., Abedin, Z., Ye, D., Burns, D. K., Raisanen, J. M., Greenberg, B. M. & Hatanpaa, K. J., Jul 1 2018, In : Annals of Neurology. 84, 1, p. 147-152 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cerebrospinal fluid chitinase-3-like protein 1 level is not an independent predictive factor for the risk of clinical conversion in radiologically isolated syndrome

Thouvenot, E., Hinsinger, G., Demattei, C., Uygunoglu, U., Castelnovo, G., Pittion-Vouyovitch, S., Okuda, D., Kantarci, O., Pelletier, D., Lehmann, S., Marin, P., Siva, A. & Lebrun, C., Mar 1 2018, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

4 Scopus citations

Cervical spinal cord atrophy: An earlymarker of progressiveMSonset

Zeydan, B., Gu, X., Atkinson, E. J., Keegan, B. M., Weinshenker, B. G., Tillema, J. M., Pelletier, D., Azevedo, C. J., Lebrun-Frenay, C., Siva, A., Okuda, D. T., Kantarci, K. & Kantarci, O. H., Mar 1 2018, In : Neurology: Neuroimmunology and NeuroInflammation. 5, 2, e435.

Research output: Contribution to journalArticle

22 Scopus citations

Classification of multiple sclerosis and non-specific white matter lesions using spherical harmonics descriptors

Wang, Y., Hansen, M., Okuda, D., Wilson, A. & Guo, X., Apr 12 2018, Proceedings of the 3rd International Workshop on Interactive and Spatial Computing, IWISC 2018. Association for Computing Machinery, p. 97-102 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Contemporary Topics in Multiple Sclerosis

Okuda, D. T., Feb 1 2018, In : Neurologic Clinics. 36, 1, p. xiii-xiv

Research output: Contribution to journalEditorial

Development of Glatopa® (Glatiramer Acetate): The First FDA-Approved Generic Disease-Modifying Therapy for Relapsing Forms of Multiple Sclerosis

Bell, C., Anderson, J., Ganguly, T., Prescott, J., Capila, I., Lansing, J. C., Sachleben, R., Iyer, M., Fier, I., Roach, J., Storey, K., Miller, P., Hall, S., Kantor, D., Greenberg, B. M., Nair, K. & Glajch, J., Oct 1 2018, In : Journal of Pharmacy Practice. 31, 5, p. 481-488 8 p.

Research output: Contribution to journalReview article

9 Scopus citations

Dietary factors and pediatric multiple sclerosis: A case-control study

for the US Network of Pediatric Multiple Sclerosis Centers, Jul 1 2018, In : Multiple Sclerosis Journal. 24, 8, p. 1067-1076 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis

on behalf of the Network of Pediatric Multiple Sclerosis Centers., May 1 2018, In : Multiple Sclerosis and Related Disorders. 22, p. 103-107 5 p.

Research output: Contribution to journalArticle

Erratum to: Neuroimmune disorders of the central nervous system in children in the molecular era (Nature Reviews Neurology, (2018), 14, 7, (433-445), 10.1038/s41582-018-0024-9)

on behalf of the attendees of the International Neuroimmune Meeting, Jul 1 2018, In : Nature Reviews Neurology. 14, 12, 1 p.

Research output: Contribution to journalComment/debate