Neurology & Neurotherapeutics - NE Outside Agreements

Research Output 1984 2019

2019

Clinical trials in multiple sclerosis: potential future trial designs

Manouchehri, N., Zhang, Y., Salter, A., Hussain, R. Z., Hartung, H. P., Hemmer, B., Linker, R., Segal, B. M., Cutter, G. & Stuve, O., May 1 2019, In : Therapeutic Advances in Neurological Disorders. 12

Research output: Contribution to journalReview article

Open Access
Multiple Sclerosis
Clinical Trials
Biomarkers
Endophenotypes
Therapeutics

Cohesin complex-associated holoprosencephaly

Kruszka, P., Berger, S. I., Casa, V., Dekker, M. R., Gaesser, J., Weiss, K., Martinez, A. F., Murdock, D. R., Louie, R. J., Prijoles, E. J., Lichty, A. W., Brouwer, O. F., Zonneveld-Huijssoon, E., Stephan, M. J., Hogue, J., Hu, P., Tanima-Nagai, M., Everson, J. L., Prasad, C., Cereda, A. & 15 others, Iascone, M., Schreiber, A., Zurcher, V., Corsten-Janssen, N., Escobar, L., Clegg, N. J., Delgado, M. R., Hajirnis, O., Balasubramanian, M., Kayserili, H., Deardorff, M., Poot, R. A., Wendt, K. S., Lipinski, R. J. & Muenke, M., Sep 1 2019, In : Brain : a journal of neurology. 142, 9, p. 2631-2643 13 p.

Research output: Contribution to journalArticle

Open Access
Holoprosencephaly
Prosencephalon
X-Linked Genes
Neurulation
Inheritance Patterns

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract

Blackburn, A. T. M., Bekheirnia, N., Uma, V. C., Corkins, M. E., Xu, Y., Rosenfeld, J. A., Bainbridge, M. N., Yang, Y., Liu, P., Madan-Khetarpal, S., Delgado, M. R., Hudgins, L., Krantz, I., Rodriguez-Buritica, D., Wheeler, P. G., Gazali, L. A., Mohamed Saeed Mohamed Al Shamsi, A., Gomez-Ospina, N., Chao, H. T., Mirzaa, G. M. & 9 others, Scheuerle, A. E., Kukolich, M. K., Scaglia, F., Eng, C., Willsey, H. R., Braun, M. C., Lamb, D. J., Miller, R. K. & Bekheirnia, M. R., Jan 1 2019, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalArticle

Intellectual Disability
Nephrons
Xenopus
RNA
Exome

Effects of cladribine tablets on lymphocyte subsets in patients with multiple sclerosis: an extended analysis of surface markers

Stuve, O., Soelberg Soerensen, P., Leist, T., Giovannoni, G., Hyvert, Y., Damian, D., Dangond, F. & Boschert, U., Jun 1 2019, In : Therapeutic Advances in Neurological Disorders. 12

Research output: Contribution to journalArticle

Open Access
Cladribine
Lymphocyte Subsets
Tablets
Multiple Sclerosis
Lymphocytes
2 Citations (Scopus)

Immunological aspects of approved MS therapeutics

Rommer, P. S., Milo, R., Han, M. H., Satyanarayan, S., Sellner, J., Hauer, L., Illes, Z., Warnke, C., Laurent, S., Weber, M. S., Zhang, Y. & Stuve, O., Jan 1 2019, In : Frontiers in immunology. 10, JULY, 1564.

Research output: Contribution to journalReview article

Open Access
ocrelizumab
Multiple Sclerosis
Pharmaceutical Preparations
Cladribine
Chronic Progressive Multiple Sclerosis
1 Citation (Scopus)

MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis

Kuhbandner, K., Hammer, A., Haase, S., Terbrack, E., Hoffmann, A., Schippers, A., Wagner, N., Hussain, R. Z., Miller-Little, W. A., Koh, A., Stoolman, J. S., Segal, B. M., Linker, R. A. & Stuve, O., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Autoimmune Experimental Encephalomyelitis
Cell Adhesion Molecules
Intestines
Lymphocytes
Multiple Sclerosis
1 Citation (Scopus)

Neurofilament light chain: An important step toward a disease biomarker in multiple sclerosis

Berger, T. & Stuve, O., Mar 5 2019, In : Neurology. 92, 10, p. 451-452 2 p.

Research output: Contribution to journalEditorial

Intermediate Filaments
Multiple Sclerosis
Biomarkers
Light
1 Citation (Scopus)
Open Access
Cannabidiol
Epilepsy
Pharmacokinetics
Pediatrics
Pharmaceutical Preparations

Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high-grade gliomas

Todorova, P. K., Fletcher-Sananikone, E., Mukherjee, B., Kollipara, R., Vemireddy, V., Xie, X-J., Guida, P. M., Story, M. D., Hatanpaa, K., Habib, A. A., Kittler, R., Bachoo, R., Hromas, R., Floyd, J. R. & Burma, S., Jan 1 2019, In : Cancer Research. 79, 14, p. 3749-3761 13 p.

Research output: Contribution to journalArticle

Glioma
DNA Damage
Radiation
Linear Energy Transfer
Neoplasms
2 Citations (Scopus)

Simplification of combination antiretroviral therapy (cART) and the brain—a real-life experience

Arendt, G., Schlonies, S., Orhan, E. & Stuve, O., Jan 1 2019, (Accepted/In press) In : Journal of NeuroVirology.

Research output: Contribution to journalArticle

HIV
Therapeutics
Lamivudine
Viral Load
Pharmaceutical Preparations
7 Citations (Scopus)

Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders

International Conference on Spinal Cord Involvement and Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders, Feb 1 2019, In : The Lancet Neurology. 18, 2, p. 185-197 13 p.

Research output: Contribution to journalReview article

Neuromyelitis Optica
Multiple Sclerosis
Spinal Cord
Spinal Cord Diseases
Biomarkers

Trials and therapies in secondary progressive MS, simplified

Manouchehri, N. & Stuve, O., Jan 1 2019, In : Nature Reviews Neurology.

Research output: Contribution to journalComment/debate

Cladribine
Chronic Progressive Multiple Sclerosis
Multiple Sclerosis
Clinical Trials
Phenotype
2018
1 Citation (Scopus)

AbobotulinumtoxinA Efficacy and Safety in Children With Equinus Foot Previously Treated With Botulinum Toxin

Dabrowski, E., Bonikowski, M., Gormley, M., Volteau, M., Picaut, P. & Delgado, M. R., Jan 1 2018, (Accepted/In press) In : Pediatric Neurology.

Research output: Contribution to journalArticle

Botulinum Toxins
Foot
Safety
Leg
Placebos
11 Citations (Scopus)

B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets

Forsthuber, T. G., Cimbora, D. M., Ratchford, J. N., Katz, E. & Stüve, O., Jan 1 2018, In : Therapeutic Advances in Neurological Disorders. 11

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Autoimmunity
B-Lymphocytes
Autoimmune Diseases of the Nervous System
Transverse Myelitis
4 Citations (Scopus)

Defining standard enzymatic dissociation methods for individual brains and spinal cords in EAE

Hussain, R. Z., Miller-Little, W. A., Doelger, R., Cutter, G. R., Loof, N., Cravens, P. D. & Stüve, O., Mar 1 2018, In : Neurology: Neuroimmunology and NeuroInflammation. 5, 2, e437.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Spinal Cord
Brain
Inbred C57BL Mouse
Cell Count
1 Citation (Scopus)

Development of a Pediatric Goal-Centered Upper Limb Spasticity Home Exercise Therapy Program for Use in a Phase-III Trial of Abobotulinumtoxina (Dysport®)

Shierk, A., Jiménez-Moreno, A. C., Roberts, H., Ackerman-Laufer, S., Backer, G., Bard-Pondarre, R., Cekmece, C., Pyrzanowska, W., Vilain, C. & Delgado, M. R., Jan 1 2018, (Accepted/In press) In : Physical and Occupational Therapy in Pediatrics.

Research output: Contribution to journalArticle

Exercise Therapy
Upper Extremity
Pediatrics
Exercise
Injections
5 Citations (Scopus)

Effect of everolimus on skin lesions in patients treated for subependymal giant cell astrocytoma and renal angiomyolipoma: Final 4-year results from the randomized EXIST-1 and EXIST-2 studies

Franz, D. N., Budde, K., Kingswood, J. C., Belousova, E., Sparagana, S., de Vries, P. J., Berkowitz, N., Ridolfi, A. & Bissler, J. J., Jan 1 2018, (Accepted/In press) In : Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journalArticle

Angiomyolipoma
Tuberous Sclerosis
Astrocytoma
Kidney
Skin
11 Citations (Scopus)

Efficacy and safety of topical rapamycin in patients with facial angiofibromas secondary to tuberous sclerosis complex the TREATMENT randomized clinical trial

TREATMENT Trial Collaborators, Jul 1 2018, In : JAMA Dermatology. 154, 7, p. 773-780 8 p.

Research output: Contribution to journalArticle

Angiofibroma
Tuberous Sclerosis
Sirolimus
Randomized Controlled Trials
Safety
1 Citation (Scopus)

Emerging drugs for primary progressive multiple sclerosis

Narayan, R. N., Forsthuber, T. & Stüve, O., Apr 3 2018, In : Expert Opinion on Emerging Drugs. 23, 2, p. 97-110 14 p.

Research output: Contribution to journalReview article

Chronic Progressive Multiple Sclerosis
Pharmaceutical Preparations
Multiple Sclerosis
ocrelizumab
Patient Selection

Epilepsy treatment patterns among patients with tuberous sclerosis complex

Song, J., Swallow, E., Said, Q., Peeples, M., Meiselbach, M., Signorovitch, J., Kohrman, M., Korf, B., Krueger, D., Wong, M. & Sparagana, S., Aug 15 2018, In : Journal of the Neurological Sciences. 391, p. 104-108 5 p.

Research output: Contribution to journalArticle

Tuberous Sclerosis
Epilepsy
Pharmaceutical Preparations
Therapeutics
Databases
4 Citations (Scopus)

Genetic and epigenetic features of rapidly progressing IDH-mutant astrocytomas

Richardson, T. E., Sathe, A. A., Kanchwala, M., Jia, G., Habib, A. A., Xiao, G., Snuderl, M., Xing, C. & Hatanpaa, K. J., Jan 1 2018, In : Journal of Neuropathology and Experimental Neurology. 77, 7, p. 542-548 7 p.

Research output: Contribution to journalArticle

Astrocytoma
Epigenomics
Chromosomal Instability
Mutation
Atlases
5 Citations (Scopus)

Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis

Jia, X., Madireddy, L., Caillier, S., Santaniello, A., Esposito, F., Comi, G., Stuve, O., Zhou, Y., Taylor, B., Kilpatrick, T., Martinelli-Boneschi, F., Cree, B. A. C., Oksenberg, J. R., Hauser, S. L. & Baranzini, S. E., Jan 1 2018, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Multiple Sclerosis
Genome
Nervous System Diseases
Hereditary Spastic Paraplegia
1 Citation (Scopus)

H-ABC Presenting as Asymmetric Dystonia in a Patient with Sturge-Weber Syndrome

Delgado, M. R. & Gonzalez-Castillo, Z., Feb 1 2018, In : Neuropediatrics. 49, 1, p. 76-77 2 p.

Research output: Contribution to journalShort survey

Sturge-Weber Syndrome
Dystonia
8 Citations (Scopus)

In-depth investigations of adolescents and adults with holoprosencephaly identify unique characteristics

Weiss, K., Kruszka, P., Guillen Sacoto, M. J., Addissie, Y. A., Hadley, D. W., Hadsall, C. K., Stokes, B., Hu, P., Roessler, E., Solomon, B., Wiggs, E., Thurm, A., Hufnagel, R. B., Zein, W. M., Hahn, J. S., Stashinko, E., Levey, E., Baldwin, D., Clegg, N. J., Delgado, M. R. & 1 others, Muenke, M., Jan 1 2018, In : Genetics in Medicine. 20, 1, p. 14-23 10 p.

Research output: Contribution to journalArticle

Holoprosencephaly
Exome
Genetic Testing
Deglutition
Type 1 Diabetes Mellitus
1 Citation (Scopus)

MRI evaluation of the effects of whole brain radiotherapy on breast cancer brain metastasis

Crowe, W., Wang, L., Zhang, Z., Varagic, J., Bourland, J. D., Chan, M. D., Habib, A. A. & Zhao, D., Jan 1 2018, (Accepted/In press) In : International Journal of Radiation Biology.

Research output: Contribution to journalArticle

Brain Neoplasms
Radiotherapy
Magnetic Resonance Imaging
Breast Neoplasms
Neoplasm Metastasis

Natalizumab: Perspectives from the bench to bedside

Shirani, A. & Stuve, O., Dec 1 2018, In : Cold Spring Harbor Perspectives in Medicine. 8, 12, a029066.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Drug Approval
Leukoencephalopathies
Relapsing-Remitting Multiple Sclerosis
Lymphocytes

PDCB does not promote CNS autoimmunity in the context of genetic susceptibility but worsens its outcome

Dubey, D., Hussain, R. Z., Miller-Little, W. A., Salter, A., Doelger, R. & Stüve, O., Oct 15 2018, In : Journal of Neuroimmunology. 323, p. 53-55 3 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Autoimmunity
4-dichlorobenzene
Spinal Cord
Brain

Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis

Cummings, M., Arumanayagam, A. C. S., Zhao, P., Kannanganat, S., Stuve, O., Karandikar, N. J. & Eagar, T. N., Aug 1 2018, In : PLoS One. 13, 8, e0200752.

Research output: Contribution to journalArticle

Presenilin-1
T-cells
Autoimmune Experimental Encephalomyelitis
encephalitis
Amyloid Precursor Protein Secretases
2 Citations (Scopus)

Similar biophysical abnormalities in glomeruli and podocytes from two distinct models

Embry, A. E., Liu, Z., Henderson, J. M., Byfield, F. J., Liu, L., Yoon, J., Wu, Z., Cruz, K., Moradi, S., Gillombardo, C. B., Hussain, R. Z., Doelger, R., Stuve, O., Chang, A. N., Janmey, P. A., Bruggeman, L. A. & Miller, R. T., May 1 2018, In : Journal of the American Society of Nephrology. 29, 5, p. 1501-1512 12 p.

Research output: Contribution to journalArticle

Podocytes
Protamines
Collagen
Wounds and Injuries
Hemodynamics
84 Citations (Scopus)

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

EXPAND Clinical Investigators, Mar 31 2018, In : The Lancet. 391, 10127, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

Chronic Progressive Multiple Sclerosis
Placebos
1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid
Bradycardia
Safety
1 Citation (Scopus)

The role of B cells in multiple sclerosis: Current and future therapies

Negron, A., Robinson, R. R., Stuve, O. & Forsthuber, T. G., Jan 1 2018, (Accepted/In press) In : Cellular Immunology.

Research output: Contribution to journalArticle

Multiple Sclerosis
B-Lymphocytes
B-Lymphocyte Subsets
Therapeutics
Cell- and Tissue-Based Therapy

TLR3 agonism re-establishes CNS immune competence during α4-integrin deficiency

Hussain, R. Z., Cravens, P. C., Doelger, R., Dentel, B., Herndon, E., Loof, N., Tsai, P., Okuda, D., Racke, M. K. & Stuve, O., Jan 1 2018, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Poly I-C
Integrins
Mental Competency
Central Nervous System
Autoimmune Experimental Encephalomyelitis
8 Citations (Scopus)

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer

Gong, K., Guo, G., Gerber, D. E., Gao, B., Peyton, M., Huang, C., Minna, J. D., Hatanpaa, K. J., Kernstine, K., Cai, L., Xie, Y., Zhu, H., Fattah, F. J., Zhang, S., Takahashi, M., Mukherjee, B., Burma, S., Dowell, J., Dao, K., Papadimitrakopoulou, V. A. & 4 others, Olivas, V., Bivona, T. G., Zhao, D. & Habib, A. A., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2500-2518 19 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Lung Neoplasms
RNA Stability
Inflammation Mediators
Oncogenes
1 Citation (Scopus)

Toe Walking: A Neurological Perspective After Referral From Pediatric Orthopaedic Surgeons

Haynes, K. B., Wimberly, R. L., VanPelt, J. M., Jo, C. H., Riccio, A. I. & Delgado, M. R., Jan 18 2018, (Accepted/In press) In : Journal of Pediatric Orthopaedics.

Research output: Contribution to journalArticle

Toes
Walking
Referral and Consultation
Pediatrics
Cerebral Palsy
2017
5 Citations (Scopus)

AbobotulinumtoxinA (Dysport®) improves function according to goal attainment in children with dynamic equinus due to cerebral palsy

Tilton, A., Russman, B., Aydin, R., Dincer, U., Escobar, R. G., Kutlay, S., Lipczyk, Z., Velez, J. C., Grandoulier, A. S., Tse, A., Picaut, P. & Delgado, M. R., 2017, In : Journal of Child Neurology. 32, 5, p. 482-487 6 p.

Research output: Contribution to journalArticle

Cerebral Palsy
Placebos
Leg
Standard of Care
Accidental Falls

Analysis of constitutive EGFR signaling regulating IRF3 transcriptional activity in cancer cells

Guo, G., Gong, K. & Habib, A. A., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1652. p. 183-189 7 p. (Methods in Molecular Biology; vol. 1652).

Research output: Chapter in Book/Report/Conference proceedingChapter

Epidermal Growth Factor Receptor
Neoplasms
Tyrosine
Ligands
Epidermal Growth Factor
23 Citations (Scopus)

A TNF-JNK-Axl-ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma

Guo, G., Gong, K., Ali, S., Ali, N., Shallwani, S., Hatanpaa, K. J., Pan, E., Mickey, B., Burma, S., Wang, D. H., Kesari, S., Sarkaria, J. N., Zhao, D. & Habib, A. A., Aug 1 2017, In : Nature Neuroscience. 20, 8, p. 1074-1084 11 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
Glioblastoma
Epidermal Growth Factor Receptor
Tumor Necrosis Factor-alpha
5 Citations (Scopus)

B-cell-Targeted therapies in relapsing forms of MS

Dubey, D., Forsthuber, T., Flanagan, E. P., Pittock, S. J. & Stüve, O., Oct 23 2017, In : Neurology: Neuroimmunology and NeuroInflammation. 4, 6, e405.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
B-Lymphocytes
Therapeutics
Phase III Clinical Trials
Anti-Idiotypic Antibodies
19 Citations (Scopus)

Biallelic mutations in human DCC cause developmental split-brain syndrome

Jamuar, S. S., Schmitz-Abe, K., D'Gama, A. M., Drottar, M., Chan, W. M., Peeva, M., Servattalab, S., Lam, A. T. N., Delgado, M. R., Clegg, N. J., Zayed, Z. A., Dogar, M. A., Alorainy, I. A., Jamea, A. A., Abu-Amero, K., Griebel, M., Ward, W., Lein, E. S., Markianos, K., Barkovich, A. J. & 6 others, Robson, C. D., Grant, P. E., Bosley, T. M., Engle, E. C., Walsh, C. A. & Yu, T. W., Mar 30 2017, In : Nature Genetics. 49, 4, p. 606-612 7 p.

Research output: Contribution to journalArticle

Split-Brain Procedure
Colorectal Neoplasms
Mutation
Central Nervous System
Diffusion Tensor Imaging
7 Citations (Scopus)

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy

Peng, Y., Shinde, D. N., Valencia, C. A., Mo, J. S., Rosenfeld, J., Cho, M. T., Chamberlin, A., Li, Z., Liu, J., Gui, B., Brockhage, R., Basinger, A., Alvarez-Leon, B., Heydemann, P., Magoulas, P. L., Lewis, A. M., Scaglia, F., Gril, S., Chong, S. C., Bower, M. & 22 others, Monaghan, K. G., Willaert, R., Plona, M. R., Dineen, R., Milan, F., Hoganson, G., Powis, Z., Helbig, K. L., Keller-Ramey, J., Harris, B., Anderson, L. C., Green, T., Sukoff Rizzo, S. J., Kaylor, J., Chen, J., Guan, M. X., Sellars, E., Sparagana, S. P., Gibson, J. B., Reinholdt, L. G., Tang, S. & Huang, T., Dec 1 2017, In : Human Molecular Genetics. 26, 24, p. 4937-4950 14 p.

Research output: Contribution to journalArticle

Optic Atrophy
Ferredoxins
Oxidoreductases
Mutation
Iron
15 Citations (Scopus)

Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially

Members of the UDN, Jul 1 2017, In : PLoS Genetics. 13, 7, e1006905.

Research output: Contribution to journalArticle

phenotype
allele
Alleles
alleles
Phenotype
21 Citations (Scopus)
Quality Improvement
Multiple Sclerosis
Brain
Health Insurance Portability and Accountability Act
Neurologists
37 Citations (Scopus)

High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS

Nash, R. A., Hutton, G. J., Racke, M. K., Popat, U., Devine, S. M., Steinmiller, K. C., Griffith, L. M., Muraro, P. A., Openshaw, H., Sayre, P. H., Stuve, O., Arnold, D. L., Wener, M. H., Georges, G. E., Wundes, A., Kraft, G. H. & Bowen, J. D., Feb 28 2017, In : Neurology. 88, 9, p. 842-852 11 p.

Research output: Contribution to journalArticle

Relapsing-Remitting Multiple Sclerosis
Cell Transplantation
Immunosuppressive Agents
Confidence Intervals
Disease-Free Survival
6 Citations (Scopus)

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme

Newman, J. P., Wang, G. Y., Arima, K., Guan, S. P., Waters, M. R., Cavenee, W. K., Pan, E., Aliwarga, E., Chong, S. T., Kok, C. Y. L., Endaya, B. B., Habib, A. A., Horibe, T., Ng, W. H., Ho, I. A. W., Hui, K. M., Kordula, T. & Lam, P. Y. P., Dec 1 2017, In : Nature Communications. 8, 1, 1913.

Research output: Contribution to journalArticle

Interleukin-13 Receptor alpha2 Subunit
Interleukin-13 Receptors
interleukins
Glioblastoma
MAP Kinase Signaling System
3 Citations (Scopus)

Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer's disease

Hussain, R. Z., Miller-Little, W. A., Lambracht-Washington, D., Jaramillo, T. C., Takahashi, M., Zhang, S., Fu, M., Cutter, G. R., Hayardeny, L., Powell, C. M., Rosenberg, R. N. & Stüve, O., Aug 15 2017, In : Journal of Neuroimmunology. 309, p. 100-110 11 p.

Research output: Contribution to journalArticle

Inbred C3H Mouse
Alzheimer Disease
Central Nervous System
Brain
Phosphorylation
1 Citation (Scopus)

Natalizumab for multiple sclerosis: A case in point for the impact of translational neuroimmunology

Shirani, A. & Stüve, O., Feb 15 2017, In : Journal of Immunology. 198, 4, p. 1381-1386 6 p.

Research output: Contribution to journalArticle

Multiple Sclerosis
Progressive Multifocal Leukoencephalopathy
Relapsing-Remitting Multiple Sclerosis
Integrins
Spinal Cord
1 Citation (Scopus)

Normal intrathecal leukocyte cell number and composition do not decrease the incidence of post–lumbar puncture headache

Stüve, O., Cataldi, F., Pradhan, V. & Gorelick, K. J., Sep 15 2017, In : Journal of Neuroimmunology. 310, p. 69-71 3 p.

Research output: Contribution to journalArticle

Leukocyte Count
Punctures
Headache
Cell Count
Spinal Puncture
2 Citations (Scopus)

Phosphatidylserine-targeted nanotheranostics for brain tumor imaging and therapeutic potential

Wang, L., Habib, A. A., Mintz, A., Li, K. C. & Zhao, D., 2017, In : Molecular Imaging. 16

Research output: Contribution to journalReview article

Phosphatidylserines
Neuroimaging
Brain Neoplasms
brain
Tumors
3 Citations (Scopus)

Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

Sparagana, S., Franz, D. N., Krueger, D. A., Bissler, J. J., Berkowitz, N., Burock, K. & Kingswood, J. C., Oct 1 2017, In : PLoS One. 12, 10, e0186235.

Research output: Contribution to journalArticle

Tuberous Sclerosis
sclerosis
clinical trials
Follicle Stimulating Hormone
amenorrhea
8 Citations (Scopus)

Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis

Richardson, T. E., Snuderl, M., Serrano, J., Karajannis, M. A., Heguy, A., Oliver, D., Raisanen, J. M., Maher, E. A., Pan, E., Barnett, S., Cai, C., Habib, A. A., Bachoo, R. M. & Hatanpaa, K. J., Apr 18 2017, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Astrocytoma
Glioblastoma
Genome
Methylation
Neoplasms