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2017

Pooled analysis of menstrual irregularities from three major clinical studies evaluating everolimus for the treatment of tuberous sclerosis complex

Sparagana, S., Franz, D. N., Krueger, D. A., Bissler, J. J., Berkowitz, N., Burock, K. & Kingswood, J. C., Oct 2017, In : PloS one. 12, 10, e0186235.

Research output: Contribution to journalArticle

4 Scopus citations

Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis

Richardson, T. E., Snuderl, M., Serrano, J., Karajannis, M. A., Heguy, A., Oliver, D., Raisanen, J. M., Maher, E. A., Pan, E., Barnett, S., Cai, C., Habib, A. A., Bachoo, R. M. & Hatanpaa, K. J., May 1 2017, In : Journal of Neuro-Oncology. 133, 1, p. 183-192 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Safety and Efficacy of Repeat Open-Label AbobotulinumtoxinA Treatment in Pediatric Cerebral Palsy

Delgado, M. R., Bonikowski, M., Carranza, J., Dabrowski, E., Matthews, D., Russman, B., Tilton, A., Velez, J. C., Grandoulier, A. S. & Picaut, P., Nov 1 2017, In : Journal of Child Neurology. 32, 13, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

The effect of everolimus on renal angiomyolipoma in pediatric patients with tuberous sclerosis being treated for subependymal giant cell astrocytoma

Bissler, J. J., Franz, D. N., Frost, M. D., Belousova, E., Bebin, E. M., Sparagana, S., Berkowitz, N., Ridolfi, A. & Kingswood, J. C., Oct 9 2017, (Accepted/In press) In : Pediatric Nephrology. p. 1-9 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

TSC2 c.1864C>T variant associated with mild cases of tuberous sclerosis complex

Farach, L. S., Gibson, W. T., Sparagana, S. P., Nellist, M., Stumpel, C. T. R. M., Hietala, M., Friedman, E., Pearson, D. A., Creighton, S. P., Wagemans, A., Segel, R., Ben-Shalom, E., Au, K. S. & Northrup, H., Mar 1 2017, In : American Journal of Medical Genetics, Part A. 173, 3, p. 771-775 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Abobotulinumtoxin A for equinus foot deformity in cerebral palsy: A randomized controlled trial

Delgado, M. R., Tilton, A., Russman, B., Benavides, O., Bonikowski, M., Carranza, J., Dabrowski, E., Dursun, N., Gormley, M., Jozwiak, M., Matthews, D., Maciag-Tymecka, I., Unlu, E., Pham, E., Tse, A. & Picaut, P., Feb 2016, In : Pediatrics. 137, 2, e20152830.

Research output: Contribution to journalArticle

30 Scopus citations

Acute relapse after initiation of Siponimod in a patient with secondary progressive MS

Hussain, R., O’Leary, S., Pacheco, F. M., Zacharias, T. E., Litvak, P., Sguigna, P., Marder, E., Kia, K., Kooner, K. & Stüve, O., Mar 1 2016, In : Journal of Neurology. 263, 3, p. 606-610 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

A single amino acid substitution prevents recognition of a dominant human aquaporin-4 determinant in the context of HLA-DRB1-03:01 by a murine TCR

Arellano, B., Hussain, R., Miller-Little, W. A., Herndon, E., Lambracht-Washington, D., Eagar, T. N., Lewis, R., Healey, D., Vernino, S., Greenberg, B. M. & Stüve, O., Apr 2016, In : PloS one. 11, 4, e0152720.

Research output: Contribution to journalArticle

3 Scopus citations

Augmented HR repair mediates acquired temozolomide resistance in glioblastoma

Del Alcazar, C. R. G., Todorova, P. K., Habib, A. A., Mukherjee, B. & Burma, S., Oct 1 2016, In : Molecular Cancer Research. 14, 10, p. 928-940 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Electromagnetic interference in intraoperative monitoring of motor evoked potentials and a wireless solution

Farajidavar, A., Seifert, J. L., Delgado, M. R., Sparagana, S., Romero-Ortega, M. I. & Chiao, J. C., Feb 1 2016, In : Medical Engineering and Physics. 38, 2, p. 87-96 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

IL-12/IL-23p40 is highly expressed in secondary lymphoid organs and the CNS during all stages of EAE, but its deletion does not affect disease perpetuation

Cravens, P. D., Hussain, R. Z., Miller-Little, W. A., Ben, L. H., Segal, B. M., Herndon, E. & Stüve, O., Oct 1 2016, In : PLoS One. 11, 10, e0165248.

Research output: Contribution to journalArticle

3 Scopus citations

Long-term use of everolimus in patients with tuberous sclerosis complex: Final results from the EXIST-1 study

Franz, D. N., Belousova, E., Sparagana, S., Bebin, E. M., Frost, M. D., Kuperman, R., Witt, O., Kohrman, M. H., Flamini, J. R., Wu, J. Y., Curatolo, P., De Vries, P. J., Berkowitz, N., Niolat, J. & Jóźwiak, S., Jun 2016, In : PloS one. 11, 6, e0158476.

Research output: Contribution to journalArticle

62 Scopus citations

Managing Disability in Progressive Multiple Sclerosis

Dubey, D., Sguigna, P. & Stüve, O., Jun 1 2016, In : Current Treatment Options in Neurology. 18, 6, 27.

Research output: Contribution to journalArticle

3 Scopus citations

Ocrelizumab for the treatment of relapsing-remitting multiple sclerosis

Menge, T., Dubey, D., Warnke, C., Hartung, H. P. & Stüve, O., Oct 2 2016, In : Expert Review of Neurotherapeutics. 16, 10, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Patterns of Disease Monitoring and Treatment Among Patients With Tuberous Sclerosis Complex-related Angiomyolipomas

Swallow, E., King, S., Song, J., Peeples, M., Signorovitch, J. E., Liu, Z., Prestifilippo, J., Frost, M., Kohrman, M., Korf, B., Krueger, D. & Sparagana, S., Nov 29 2016, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

2 Scopus citations

Phosphatidylserine-targeted liposome for enhanced gliomaselective imaging

Zhang, L., Habib, A. A. & Zhao, D., Jan 1 2016, In : Oncotarget. 7, 25, p. 38693-38706 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis

Shirani, A., Okuda, D. T. & Stüve, O., Jan 1 2016, In : Neurotherapeutics. 13, 1, p. 58-69 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

Tumefactive demyelination following herbal supplement use: Cause or coincidence?

Dubey, D., Golden, E., Suss, A., Cano, C. A., Krishnan, G. & Stuve, O., Apr 1 2016, In : Journal of Postgraduate Medicine. 62, 2, p. 136-137 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
6 Scopus citations

Variants Within TSC2 Exons 25 and 31 Are Very Unlikely to Cause Clinically Diagnosable Tuberous Sclerosis

Ekong, R., Nellist, M., Hoogeveen-Westerveld, M., Wentink, M., Panzer, J., Sparagana, S., Emmett, W., Dawson, N. L., Malinge, M. C., Nabbout, R., Carbonara, C., Barberis, M., Padovan, S., Futema, M., Plagnol, V., Humphries, S. E., Migone, N. & Povey, S., Apr 1 2016, In : Human Mutation. 37, 4, p. 364-370 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Vestibular hypofunction after monosodium glutamate ingestion: broadening the spectrum of ‘Chinese restaurant syndrome’

Leussink, V. I., Hartung, H. P., Stüve, O. & Kieseier, B. C., May 1 2016, In : Journal of Neurology. 263, 5, p. 1027-1028 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Will biomarkers determine what is next in multiple sclerosis? Biomarkers in multiple sclerosis

Stüve, O. & Racke, M. K., May 1 2016, In : JAMA Neurology. 73, 5, p. 496-497 2 p.

Research output: Contribution to journalArticle

4 Scopus citations
2015

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

Camacho, C. V., Todorova, P. K., Hardebeck, M. C., Tomimatsu, N., Gil del Alcazar, C. R., Ilcheva, M., Mukherjee, B., McEllin, B., Vemireddy, V., Hatanpaa, K., Story, M. D., Habib, A. A., Murty, V. V., Bachoo, R. & Burma, S., Feb 19 2015, In : Oncogene. 34, 8, p. 1064-1072 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy based on functional near-infrared spectroscopy

Cao, J., Khan, B., Hervey, N., Tian, F., Delgado, M. R., Clegg, N. J., Smith, L., Roberts, H., Tulchin-Francis, K., Shierk, A., Shagman, L., Macfarlane, D., Liu, H. & Alexandrakis, G., Apr 1 2015, In : Journal of Biomedical Optics. 20, 4, 046009.

Research output: Contribution to journalArticle

14 Scopus citations

High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for relapsing-remitting multiple sclerosis (HALT-MS): A 3-year interim report

Nash, R. A., Hutton, G. J., Racke, M. K., Popat, U., Devine, S. M., Griffith, L. M., Muraro, P. A., Openshaw, H., Sayre, P. H., Stüve, O., Arnold, D. L., Spychala, M. E., McConville, K. C., Harris, K. M., Phippard, D., Georges, G. E., Wundes, A., Kraft, G. H. & Bowen, J. D., Feb 1 2015, In : JAMA neurology. 72, 2, p. 159-169 11 p.

Research output: Contribution to journalArticle

105 Scopus citations

In Memoriam: Jean Lindenmann (1924-2015): A Circuitous Interfering Power in Neurology

Stüve, O., Jun 1 2015, In : JAMA Neurology. 72, 6, p. 728-729 2 p.

Research output: Contribution to journalArticle

Ligand-independent EGFR signaling

Guo, G., Gong, K., Wohlfeld, B., Hatanpaa, K. J., Zhao, D. & Habib, A. A., Sep 1 2015, In : Cancer Research. 75, 17, p. 3436-3441 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

Natalizumab to fingolimod: Questions answered, unanswered, and unasked

Stüve, O. & Bourdette, D., Jul 7 2015, In : Neurology. 85, 1, p. 14-15 2 p.

Research output: Contribution to journalArticle

Patients characteristics influencing the longitudinal utilization of steroids in multiple sclerosis - an observational study

the German Multiple Sclerosis (MS) Registry of the German National MS Society (DMSG), Jun 1 2015, In : European Journal of Clinical Investigation. 45, 6, p. 587-593 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Smoking beyond multiple sclerosis diagnosis: A risk factor still worth modifying

Goldman, M. D. & Stüve, O., Oct 1 2015, In : JAMA Neurology. 72, 10, p. 1105-1106 2 p.

Research output: Contribution to journalArticle

Spinal gout: A rare cause of paraplegia

Dubey, D., Steen, E., Sawhney, A. & Stuve, O., Mar 1 2015, In : Neurology India. 63, 2, p. 284-285 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

The spectrum of autoimmune encephalopathies

Dubey, D., Sawhney, A., Greenberg, B., Lowden, A., Warnack, W., Khemani, P., Stuve, O. & Vernino, S., Oct 15 2015, In : Journal of Neuroimmunology. 287, p. 93-97 5 p., 476194.

Research output: Contribution to journalArticle

28 Scopus citations

Toward tract-specific fractional anisotropy (TSFA) at crossing-fiber regions with clinical diffusion MRI

Mishra, V., Guo, X., Delgado, M. R. & Huang, H., Dec 1 2015, In : Magnetic Resonance in Medicine. 74, 6, p. 1768-1779 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Using whole-exome sequencing to identify variants inherited from mosaic parents

Rios, J. J. & Delgado, M. R., Apr 14 2015, In : European Journal of Human Genetics. 23, 4, p. 547-550 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII

Li, L., Chakraborty, S., Yang, C. R., Hatanpaa, K. J., Cipher, D. J., Puliyappadamba, V. T., Rehman, A., Jiwani, A. J., Mickey, B., Madden, C., Raisanen, J., Burma, S., Saha, D., Wang, Z., Pingle, S. C., Kesari, S., Boothman, D. A. & Habib, A. A., Aug 14 2014, In : Oncogene. 33, 33, p. 4253-4264 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Brain MRI abnormalities and spectrum of neurological and clinical findings in three patients with proximal 16p11.2 microduplication

Filges, I., Sparagana, S., Sargent, M., Selby, K., Schlade-Bartusiak, K., Lueder, G. T., Robichaux-Viehoever, A., Schlaggar, B. L., Shimony, J. S. & Shinawi, M., Aug 2014, In : American Journal of Medical Genetics, Part A. 164, 8, p. 2003-2012 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

CD19 as a molecular target in CNS autoimmunity

Stüve, O., Warnke, C., Deason, K., Stangel, M., Kieseier, B. C., Hartung, H. P., Von Büdingen, H. C., Centonze, D., Forsthuber, T. G. & Knappertz, V., 2014, In : Acta Neuropathologica. 128, 2, p. 177-190 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks

Chakraborty, S., Li, L., Puliyappadamba, V. T., Guo, G., Hatanpaa, K. J., Mickey, B., Souza, R. F., Vo, P., Herz, J., Chen, M. R., Boothman, D. A., Pandita, T. K., Wang, D. H., Sen, G. C. & Habib, A. A., 2014, In : Nature communications. 5, 5811.

Research output: Contribution to journalArticle

37 Scopus citations

Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study

Franz, D. N., Belousova, E., Sparagana, S., Bebin, E. M., Frost, M., Kuperman, R., Witt, O., Kohrman, M. H., Flamini, J. R., Wu, J. Y., Curatolo, P., de Vries, P. J., Berkowitz, N., Anak, O., Niolat, J. & Jozwiak, S., Jan 1 2014, In : The Lancet Oncology. 15, 13, p. 1513-1520 8 p.

Research output: Contribution to journalArticle

107 Scopus citations

Genomic analyses of patients with unexplained early-onset scoliosis

Gao, X., Gotway, G., Rathjen, K., Johnston, C., Sparagana, S. & Wise, C. A., Sep 2014, In : Spine Deformity. 2, 5, p. 324-332 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Heat exposure and bicycling trigger recurrent aseptic meningitis: A case report

Stuve, O., Marder, E., Okai, A., Stettner, M. & Kieseier, B. C., Dec 31 2014, In : BMC Neurology. 14, 1, 230.

Research output: Contribution to journalArticle

1 Scopus citations
19 Scopus citations
35 Scopus citations

Immunopathogenesis of Neuromyelitis Optica

Levy, M., Wildemann, B., Jarius, S., Orellano, B., Sasidharan, S., Weber, M. S. & Stuve, O., 2014, In : Advances in Immunology. 121, p. 213-242 30 p.

Research output: Contribution to journalArticle

33 Scopus citations

Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma

Gil Del Alcazar, C. R., Hardebeck, M. C., Mukherjee, B., Tomimatsu, N., Gao, X., Yan, J., Xie, X. J., Bachoo, R., Li, L., Habib, A. A. & Burma, S., 2014, In : Clinical Cancer Research. 20, 5, p. 1235-1248 14 p.

Research output: Contribution to journalArticle

93 Scopus citations

Monoclonal antibodies in treatment of multiple sclerosis

Rommer, P. S., Dudesek, A., Stüve, O. & Zettl, U. K., Mar 1 2014, In : Clinical and Experimental Immunology. 175, 3, p. 373-384 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Motion tracking and electromyography-assisted identification of mirror hand contributions to functional near-infrared spectroscopy images acquired during a finger-tapping task performed by children with cerebral palsy

Hervey, N., Khan, B., Shagman, L., Tian, F., Delgado, M. R., Tulchin-Francis, K., Shierk, A., Roberts, H., Smith, L., Reid, D., Clegg, N. J., Liu, H., Macfarlane, D. & Alexandrakis, G., Oct 1 2014, In : Neurophotonics. 1, 2, 14054PR.

Research output: Contribution to journalArticle

5 Scopus citations

Multiple sclerosis disease progression and paradichlorobenzene a tale of mothballs and toilet cleaner

Hession, R. M., Sharma, V., Spiegel, D. E., Tat, C., Hwang, D. G., Dieppa, M., Mahdavi, Z., Marder, E. & Stüve, O., Feb 2014, In : JAMA Neurology. 71, 2, p. 228-232 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Requirement for safety monitoring for approved multiple sclerosis therapies: An overview

Rommer, P. S., Zettl, U. K., Kieseier, B., Hartung, H. P., Menge, T., Frohman, E., Greenberg, B., Hemmer, B. & Stuve, O., Mar 2014, In : Clinical and Experimental Immunology. 175, 3, p. 397-407 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance

Castro-Rojas, C., Deason, K., Hussain, R. Z., Hayardeny, L., Cravens, P. C., Yarovinsky, F., Eagar, T. N., Arellano, B. & Stüve, O., Nov 15 2014, In : Journal of Neuroimmunology. 276, 1-2, p. 232-235 4 p.

Research output: Contribution to journalArticle