Neurology & Neurotherapeutics - NE Outside Agreements

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2007

Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy

Sanger, T. D., Bastian, A., Brunstrom, J., Damiano, D., Delgado, M., Dure, L., Gaebler-Spira, D., Hoon, A., Mink, J. W., Sherman-Levine, S., Welty, L. J., Arrick, S., Clegg, N., Lane, J., Pendley, D., Plumb, S., Simpson, J., Stashinko, E., Vierhile, A., Pesci, T. J. & 17 others, Kalb, D., Kitsuwa-Lowe, J., Lang, C., Renneker, K., Schuberth, L., Silva, A., Weber, C., Weber, J., Wingert, J., Yasakawa, A., Anderson, J., Hudson, B., Murphy, K., Polholsky, T., Fisher, P., Hahn, J. & Sita, P., May 1 2007, In : Journal of child neurology. 22, 5, p. 530-537 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

SNS-032 prevents tumor cell-induced angiogenesis by inhibiting vascular endothelial growth factor

Ali, N. A., Choy, H., Habib, A. A. & Saha, D., May 2007, In : Neoplasia. 9, 5, p. 370-381 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

Weber, M. S., Prod'homme, T., Youssef, S., Dunn, S. E., Rundle, C. D., Lee, L., Patarroyo, J. C., Stüve, O., Sobel, R. A., Steinman, L. & Zamvil, S. S., Aug 1 2007, In : Nature medicine. 13, 8, p. 935-943 9 p.

Research output: Contribution to journalArticle

347 Scopus citations

W. Ian McDonald, MB, ChB, PhD (1933-2006): the multiple sclerosis physician-scientist of the 20th century.

Frohman, E., Stuve, O. & Miller, D. H., Mar 2007, In : Archives of neurology. 64, 3, p. 452-454 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
2006

Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis

Stuve, O., Marra, C. M., Bar-Or, A., Niino, M., Cravens, P. D., Cepok, S., Frohman, E., Phillips, J. T., Arendt, G., Jerome, K. R., Cook, L., Grand'Maison, F., Hemmer, B., Monson, N. L. & Racke, M. K., Oct 17 2006, In : Archives of neurology. 63, 10, p. 1383-1387 5 p.

Research output: Contribution to journalArticle

214 Scopus citations

Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells

Ramnarain, D. B., Park, S., Lee, D. Y., Hatanpaa, K. J., Scoggin, S. O., Otu, H., Libermann, T. A., Raisanen, J. M., Ashfaq, R., Wong, E. T., Wu, J., Elliott, R. & Habib, A. A., Jan 15 2006, In : Cancer research. 66, 2, p. 867-874 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

Evidence for involvement of TRE-2 (USP6) oncogene, low-copy repeat and acrocentric heterochromatin in two families with chromosomal translocations

Ou, Z., Jarmuz, M., Sparagana, S. P., Michaud, J., Décarie, J. C., Yatsenko, S. A., Nowakowska, B., Furman, P., Shaw, C. A., Shaffer, L. G., Lupski, J. R., Chinault, A. C., Cheung, S. W. & Stankiewicz, P., Sep 1 2006, In : Human genetics. 120, 2, p. 227-237 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Factor analysis of neuroanatomical and clinical characteristics of holoprosencephaly

Hahn, J. S., Barkovich, A. J., Stashinko, E. E., Kinsman, S. L., Delgado, M. R. & Clegg, N. J., Aug 1 2006, In : Brain and Development. 28, 7, p. 413-419 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Immune surveillance in multiple sclerosis patients treated with natalizumab

Stuve, O., Marra, C. M., Jerome, K. R., Cook, L., Cravens, P. D., Cepok, S., Frohman, E., Phillips, T., Arendt, G., Hemmer, B., Monson, N. L. & Racke, M. K., May 1 2006, In : Annals of Neurology. 59, 5, p. 743-747 5 p.

Research output: Contribution to journalArticle

341 Scopus citations

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

Stüve, O., Youssef, S., Weber, M. S., Nessler, S., Von Büdingen, H. C., Hemmer, B., Prod'homme, T., Sobel, R. A., Steinman, L. & Zamvil, S. S., Apr 1 2006, In : Journal of Clinical Investigation. 116, 4, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Inhibition by mitoxantrone of in vitro migration of immunocompetent cells: A possible mechanism for therapeutic efficacy in the treatment of multiple sclerosis

Kopadze, T., Dehmel, T., Hartung, H. P., Stüve, O. & Kieseier, B. C., Nov 1 2006, In : Archives of neurology. 63, 11, p. 1572-1578 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp

Nie, D. Y., Ma, Q. H., Law, J. W. S., Chia, C. P., Dhingra, N. K., Shimoda, Y., Yang, W. L., Gong, N., Chen, Q. W., Xu, G., Hu, Q. D., Chow, P. K. H., Ng, Y. K., Ling, E. A., Watanabe, K., Xu, T. L., Habib, A. A., Schachner, M. & Xiao, Z. C., Aug 2006, In : Neuron Glia Biology. 2, 3, p. 151-164 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Prion protein gene codon 129 modulates clinical course of neurological Wilson disease

Grubenbecher, S., Stüve, O., Hefter, H. & Korth, C., Apr 1 2006, In : NeuroReport. 17, 5, p. 549-552 4 p.

Research output: Contribution to journalArticle

16 Scopus citations
2005

Clinical stabilization and effective B-lymphocyte depletion in the cerebrospinal fluid and peripheral blood of a patient with fulminant relapsing-remitting multiple sclerosis

Stüve, O., Cepok, S., Elias, B., Saleh, A., Hartung, H. P., Hemmer, B. & Kieseier, B. C., Oct 1 2005, In : Archives of neurology. 62, 10, p. 1620-1623 4 p.

Research output: Contribution to journalArticle

125 Scopus citations

Long-term outcome of transcatheter embolization of renal angiomyolipomas due to tuberous sclerosis complex

Ewalt, D. H., Diamond, N., Rees, C., Sparagana, S. P., Delgado, M., Batchelor, L. & Roach, E. S., Nov 2005, In : Journal of Urology. 174, 5, p. 1764-1766 3 p.

Research output: Contribution to journalArticle

86 Scopus citations

Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro

Neuhaus, O., Wiendl, H., Kieseier, B. C., Archelos, J. J., Hemmer, B., Stüve, O. & Hartung, H. P., Nov 1 2005, In : Journal of Neuroimmunology. 168, 1-2, p. 128-137 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

Putative mechanisms of action of statins in multiple sclerosis - Comparison to interferon-β and glatiramer acetate

Neuhaus, O., Stüve, O., Archelos, J. J. & Hartung, H. P., Jun 15 2005, In : Journal of the Neurological Sciences. 233, 1-2, p. 173-177 5 p.

Research output: Contribution to journalArticle

21 Scopus citations
2004

Diagnosis of tuberous sclerosis complex

Roach, E. S. & Sparagana, S. P., Sep 2004, In : Journal of child neurology. 19, 9, p. 643-649 7 p.

Research output: Contribution to journalArticle

220 Scopus citations

Mitoxantrone as a potential therapy for primary progressive multiple sclerosis

Stüve, O., Kita, M., Pelletier, D., Fox, R. J., Stone, J., Goodkin, D. E. & Zamvil, S. S., Jun 2004, In : Multiple Sclerosis. 10, SUPPL. 1, p. S58-S61

Research output: Contribution to journalArticle

15 Scopus citations
2003

Acute deformity correction of lower extremities under SSEP-monitoring control

Makarov, M. R., Samchukov, M. L., Birch, J. G., Johnston, C. E., Delgado, M. R., Rampy, P. L. & Van Allen, E. M., Jan 1 2003, In : Journal of Pediatric Orthopaedics. 23, 4, p. 470-477 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Classification and definition of disorders causing hypertonia in childhood

Sanger, T. D., Delgado, M. R., Gaebler-Spira, D., Hallett, M. & Mink, J. W., Jan 1 2003, In : Pediatrics. 111, 1, p. e89-e97

Research output: Contribution to journalArticle

Open Access
442 Scopus citations

Electroencephalography in holoprosencephaly: Findings in children without epilepsy

Hahn, J. S., Delgado, M. R., Clegg, N. J., Sparagana, S. P., Gerace, K. L., Barkovich, A. J. & Olson, D. M., Oct 1 2003, In : Clinical Neurophysiology. 114, 10, p. 1908-1917 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
34 Scopus citations

Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination

Chun, S. J., Rasband, M. N., Sidman, R. L., Habib, A. A. & Vartanian, T., Oct 27 2003, In : Journal of Cell Biology. 163, 2, p. 397-408 12 p.

Research output: Contribution to journalArticle

121 Scopus citations

Middle interhemispheric variant of holoprosencephaly associated with diffuse polymicrogyria

Takanashi, J. I., Barkovich, A. J., Clegg, N. J. & Delgado, M. R., Mar 1 2003, In : American Journal of Neuroradiology. 24, 3, p. 394-397 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Raúl Calderón-González, MD, 1937—2003: Father of Child Neurology in Mexico

Delgado, M. R., 2003, In : Journal of Child Neurology. 18, 1, p. 82 1 p.

Research output: Contribution to journalArticle

Seizure remission and antiepileptic drug discontinuation in children with tuberous sclerosis complex

Sparagana, S. P., Delgado, M. R., Batchelor, L. L. & Roach, E. S., Sep 1 2003, In : Archives of neurology. 60, 9, p. 1286-1289 4 p.

Research output: Contribution to journalArticle

40 Scopus citations
2002

Cutting edge: Oral type I IFN-τ promotes a Th2 bias and enhances suppression of autoimmune encephalomyelitis by oral glatiramer acetate

Soos, J. M., Stüve, O., Youssef, S., Bravo, M., Johnson, H. M., Weiner, H. L. & Zamvil, S. S., Sep 1 2002, In : Journal of Immunology. 169, 5, p. 2231-2235 5 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations

Long-term tolerability and efficacy of lamotrigine in pediatic patients with epilepsy

Duchowny, M., Gilman, J., Messenheimer, J., Womble, G., Risner, M., Ayala, R., Konkol, R., Campbell, R., Crumrine, P. K., Cruse, R. P., Delgado, M., Fountain, N., Enlow, T., Fakhoury, T. A., Casadonte, J., Frank, L. M., Graf, W., Griebel, M. L., Griesemer, D. A., Wannamaker, B. & 33 others, Olson, D. M., Silverstein, F., Hurst, D., Jackson, A., Laxer, K. D., Bluestone, D., Maria, B., Lassiter, A., Levisohn, P. M., Libenson, M., Mitchell, W., Montouris, G., Murphy, J., Oommen, K. J., Park, Y. D., Parks, B. R., Snodgrass, S., Pellock, J. M., Ramsay, E., Ritter, F. J., Schimschock, J. R., Khan, A., Shuman, R., Tennison, M., Cheng, R. D., Turk, W., Wise, M. S., Bebin, E., Gonzalez, A., Ruiz, M., Gonzalez, R. C., Llamosa, G. & Saiers, J., 2002, In : Journal of child neurology. 17, 4, p. 278-285 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Middle interhemispheric variant of holoprosencephaly: A distinct cliniconeuroradiologic subtype

Lewis, A. J., Simon, E. M., Barkovich, A. J., Clegg, N. J., Delgado, M. R., Levey, E. & Hahn, J. S., Dec 24 2002, In : Neurology. 59, 12, p. 1860-1865 6 p.

Research output: Contribution to journalArticle

81 Scopus citations

MRI shows abnormal white matter maturation in classical holoprosencephaly

Barkovich, A. J., Simon, E. M., Glenn, O. A., Clegg, N. J., Kinsman, S. L., Delgado, M. & Hahn, J. S., Dec 24 2002, In : Neurology. 59, 12, p. 1968-1971 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Neuroanatomy of holoprosencephaly as predictor of function: Beyond the face predicting the brain

Plawner, L. L., Delgado, M. R., Miller, V. S., Levey, E. B., Kinsman, S. L., Barkovich, A. J., Simon, E. M., Clegg, N. J., Sweet, V. T., Stashinko, E. E. & Hahn, J. S., Oct 8 2002, In : Neurology. 59, 7, p. 1058-1066 9 p.

Research output: Contribution to journalArticle

77 Scopus citations

Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA)

Patarroyo, J. C., Stuve, O., Piskurich, J. F., Hauser, S. L., Oksenberg, J. R. & Zamvil, S. S., Feb 1 2002, In : Genes and Immunity. 3, 1, p. 34-37 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

Youssef, S., Stüve, O., Patarroyo, J. O., Ruiz, P. J., Radosevich, J. L., Mi Hur, E., Bravo, M., Mitchell, D. J., Sobel, R. A., Stelnman, L. & Zamvil, S. S., Nov 7 2002, In : Nature. 420, 6911, p. 78-84 7 p.

Research output: Contribution to journalArticle

925 Scopus citations

The middle interhemispheric variant of holoprosencephaly

Simon, E. M., Hevner, R. F., Pinter, J. D., Clegg, N. J., Delgado, M., Kinsman, S. L., Hahn, J. S. & Barkovich, A. J., Feb 5 2002, In : American Journal of Neuroradiology. 23, 1, p. 151-155 5 p.

Research output: Contribution to journalArticle

114 Scopus citations

The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease

Stüve, O., Youssef, S., Slavin, A. J., King, C. L., Patarroyo, J. C., Hirschberg, D. L., Brickey, W. J., Soos, J. M., Piskurich, J. F., Chapman, H. A. & Zamvil, S. S., Dec 15 2002, In : Journal of Immunology. 169, 12, p. 6720-6732 13 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations
2001

Epidermal growth factor receptor induced apoptosis: Potentiation by inhibition of Ras signaling

Högnason, T., Chatterjee, S., Vartanian, T., Ratan, R. R., Ernewein, K. M. & Habib, A. A., Feb 23 2001, In : FEBS Letters. 491, 1-2, p. 9-15 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Felbamate urolithiasis

Sparagana, S. P., Strand, W. R. & Adams, R. C., May 29 2001, In : Epilepsia. 42, 5, p. 682-685 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Holoprosencephaly due to mutations in ZIC2: Alanine tract expansion mutations may be caused by parental somatic recombination

Brown, L. Y., Odent, S., David, V., Blayau, M., Dubourg, C., Apacik, C., Delgado, M. A., Hall, B. D., Reynolds, J. F., Sommer, A., Wieczorek, D., Brown, S. A. & Muenke, M., Apr 1 2001, In : Human molecular genetics. 10, 8, p. 791-796 6 p.

Research output: Contribution to journalArticle

Open Access
135 Scopus citations

Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-γ-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4+ T-cell activation

Soos, J. M., Krieger, J. I., Stüve, O., King, C. L., Patarroyo, J. C., Aldape, K., Wosik, K., Slavin, A. J., Nelson, P. A., Antel, J. P. & Zamvil, S. S., Dec 1 2001, In : GLIA. 36, 3, p. 391-405 15 p.

Research output: Contribution to journalArticle

35 Scopus citations

Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity

Slavin, A. J., Soos, J. M., Stuve, O., Patarroyo, J. C., Weiner, H. L., Fontana, A., Bikoff, E. K. & Zamvil, S. S., Jan 1 2001, In : Journal of Clinical Investigation. 108, 8, p. 1133-1139 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

The absence of interictal spikes with documented seizures suggests extratemporal epilepsy

Stüve, O., Dodrill, C. B., Holmes, M. D. & Miller, J. W., Jul 14 2001, In : Epilepsia. 42, 6, p. 778-781 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

The dorsal cyst in holoprosencephaly and the role of the thalamus in its formation

Simon, E. M., Hevner, R. F., Pinter, J. D., Clegg, N. J., Delgado, M., Kinsman, S. L., Hahn, J. S. & Barkovich, A. J., Oct 4 2001, In : Neuroradiology. 43, 9, p. 787-791 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-κB (NF-κB)-inducing kinase to activate NF-κB: Identification of a novel receptor-tyrosine kinase signalosome

Habib, A. A., Chatterjee, S., Park, S. K., Ratan, R. R., Lefebvre, S. & Vartanian, T., Mar 23 2001, In : Journal of Biological Chemistry. 276, 12, p. 8865-8874 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Use of botulinum toxin type A in pediatric patients with cerebral palsy: A three-center retrospective chart review

Gormley, M. E., Gaebler-Spira, D. & Delgado, M. R., Jan 1 2001, In : Journal of child neurology. 16, 2, p. 113-118 6 p.

Research output: Contribution to journalArticle

41 Scopus citations
2000

Abnormal sudomotor function in the hypomelanotic macules of tuberous sclerosis complex

Chudnow, R. S., Wolfe, G. I., Sparagana, S. P., Delgado, M. R., Batchelor, L. & Roach, E. S., Jan 1 2000, In : Journal of child neurology. 15, 8, p. 529-532 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Adjunctive therapy with oxcarbazepine in children with partial seizures

the Oxcarbazepine Pediatric Study Group, Jun 27 2000, In : Neurology. 54, 12, p. 2237-2244 8 p.

Research output: Contribution to journalArticle

166 Scopus citations
15 Scopus citations

Dopa-responsive dystonia due to a large deletion in the GTP cyclohydrolase I gene

Furukawa, Y., Guttman, M., Sparagana, S. P., Trugman, J. M., Hyland, K., Wyatt, P., Lang, A. E., Rouleau, G. A., Shimadzu, M. & Kish, S. J., Apr 19 2000, In : Annals of Neurology. 47, 4, p. 517-520 4 p.

Research output: Contribution to journalArticle

53 Scopus citations

Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor

Openshaw, H., Stuve, O., Antel, J. P., Nash, R., Lund, B. T., Weiner, L. P., Kashyap, A., McSweeney, P. & Forman, S., Jun 13 2000, In : Neurology. 54, 11, p. 2147-2150 4 p.

Research output: Contribution to journalArticle

127 Scopus citations