Obstetrics & Gynecology - Green Center

Research output

Research output per year 2002 2006 2007 2011 2013 2016 2017 2018 2023

• 55 Article
• 5 Review article
• 4 Comment/debate
• 3 Chapter
• 1 More
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2023

  Functional Analysis of Histone ADP-Ribosylation In Vitro and in Cells

  Huang, D., Edwards, A. D., Gong, X. & Kraus, W. L., 2023, Methods in Molecular Biology. Humana Press Inc., p. 157-192 36 p. (Methods in Molecular Biology; vol. 2609).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • ADP-Ribosylation 100%
  • Histones 68%
  • In Vitro Techniques 31%
  • Post Translational Protein Processing 24%
  • Chromatin 21%
• 2022

  Oncohistone Mutations Occur at Functional Sites of Regulatory ADP-Ribosylation

  Huang, D., Camacho, C. V., Martire, S., Nagari, A., Setlem, R., Gong, X., Edwards, A. D., Chiu, S. P., Banaszynski, L. A. & Lee Kraus, W., Jul 1 2022, In: Cancer research. 82, 13, p. 2361-2377 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Histones 68%
  • Mutation 40%
  • Growth 26%
  • Neoplasms 20%
  4 Scopus citations

• The expanding universe of PARP1-mediated molecular and therapeutic mechanisms

  Huang, D. & Kraus, W. L., Jun 16 2022, In: Molecular cell. 82, 12, p. 2315-2334 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Poly(ADP-ribose) Polymerase Inhibitors 96%
  • Post Translational Protein Processing 74%
  • Biological Phenomena 70%
  • Gene Expression Regulation 39%
  71 Scopus citations
• 2021

  Erratum: PARP-1 suppresses adiponectin expression through poly(ADP-ribosyl)ation of PPARγin cardiac fibroblasts (Cardiovascular Research (2009) 81:1 (98-107) DOI: 10.1093/cvr/cvn264)

  Huang, D., Yang, C., Wang, Y., Liao, Y. & Huang, K., Dec 1 2021, In: Cardiovascular Research. 117, 14, p. 2822 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Poly ADP Ribosylation 100%
  • Ethics Committees 80%
  • Adiponectin 70%
  • Fibroblasts 48%

• Identification of PARP-7 substrates reveals a role for marylation in microtubule control in Ovarian cancer cells

  Palavalli Parsons, L. H., Challa, S., Gibson, B. A., Nandu, T., Stokes, M. S., Huang, D., Lea, J. S. & Lee Kraus, W., Jan 2021, In: eLife. 10, p. 1-61 61 p., e60481.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Microtubules 70%
  • Ovarian Neoplasms 66%
  • Biological Role 30%
  • Protein 30%
  30 Scopus citations
• 2020

  Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis

  Huang, D., Camacho, C. V., Setlem, R., Ryu, K. W., Parameswaran, B., Gupta, R. K. & Kraus, W. L., Sep 17 2020, In: Molecular cell. 79, 6, p. 934-949.e14

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Adipogenesis 87%
  • Histones 68%
  • Phosphorylation 50%
  • NAD+ synthase 35%
  37 Scopus citations

• Specific Binding of snoRNAs to PARP-1 Promotes NAD⁺-Dependent Catalytic Activation

  Huang, D., Kim, D. S. & Kraus, W. L., Apr 28 2020, In: Biochemistry. 59, 16, p. 1559-1564 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Small Nucleolar RNA 100%
  • Poly (ADP-Ribose) Polymerase-1 95%
  • Poly(ADPribose) 94%
  • NAD 71%
  • RNA 27%
  17 Scopus citations
• 2018

  An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors

  Bratkowski, M., Yang, X. & Liu, X., Dec 1 2018, In: Scientific reports. 8, 1, 9092.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GSK126 100%
  • Polycomb Repressive Complex 2 94%
  • GSK343 21%
  • Fungi 18%
  • Chaetomium 17%
  24 Scopus citations

• Erratum to: Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs (Nature Communications, (2017), 8, 1, (1737), 10.1038/s41467-017-01713-y)

  Partin, A. C., Ngo, T. D., Herrell, E., Jeong, B. C., Hon, G. & Nam, Y., Dec 1 2018, In: Nature communications. 9, 1, 3852.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • MicroRNA 100%
  • Heme 90%
  • positioning 80%
  • Communication 74%
  • document markup languages 72%

• Generating protein-linked and protein-free mono-, oligo-, and poly(ADP-ribose) in vitro

  Lin, K. Y., Huang, D. & Lee Kraus, W., 2018, Methods in Molecular Biology. Humana Press Inc., p. 91-108 18 p. (Methods in Molecular Biology; vol. 1813).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • oligo adenosine diphosphoribose 100%
  • Adenosine Diphosphate Ribose 62%
  • Poly Adenosine Diphosphate Ribose 60%
  • ADP-Ribosylation 59%
  • Poly(ADP-ribose) Polymerases 41%
  11 Scopus citations

• Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

  Huang, F., Ni, M., Chalishazar, M. D., Huffman, K. E., Kim, J., Cai, L., Shi, X., Cai, F., Zacharias, L. G., Ireland, A. S., Li, K., Gu, W., Kaushik, A. K., Liu, X., Gazdar, A. F., Oliver, T. G., Minna, J. D., Hu, Z. & DeBerardinis, R. J., Sep 4 2018, In: Cell Metabolism. 28, 3, p. 369-382.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Inosine Monophosphate 100%
  • Small Cell Lung Carcinoma 83%
  • Oxidoreductases 68%
  • Guanosine 46%
  • Nucleotides 22%
  116 Scopus citations

• Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28

  Wang, L., Rowe, R. G., Jaimes, A., Yu, C., Nam, Y., Pearson, D. S., Zhang, J., Xie, X., Marion, W., Heffron, G. J., Daley, G. Q. & Sliz, P., Jun 5 2018, In: Cell Reports. 23, 10, p. 3091-3101 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cold-Shock Response 100%
  • MicroRNA 92%
  • Zinc 72%
  • N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 63%
  • MicroRNAs 63%
  71 Scopus citations

• Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor

  Doxtader, K. A., Wang, P., Scarborough, A. M., Seo, D., Conrad, N. K. & Nam, Y., Sep 20 2018, In: Molecular cell. 71, 6, p. 1001-1011.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • S-Adenosylmethionine 100%
  • Homeostasis 55%
  • N(6)-methyladenosine 40%
  • RNA 35%
  • Methyltransferases 28%
  135 Scopus citations

• Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk

  Bratkowski, M., Unarta, I. C., Zhu, L., Shubbar, M., Huang, X. & Liu, X., Feb 2 2018, In: Journal of Biological Chemistry. 293, 5, p. 1651-1665 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transcription Factor TFIIB 100%
  • Peptide Initiation Factors 81%
  • Dissection 54%
  • Transcription Factors 47%
  • Plastic Property 36%
  11 Scopus citations

• Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding

  Chen, S., Jiao, L., Shubbar, M., Yang, X. & Liu, X., Mar 1 2018, In: Molecular cell. 69, 5, p. 840-852.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nucleosomes 100%
  • Chromatin 75%
  • Genetic Translocation 71%
  • Histones 53%
  • C2 Domains 41%
  94 Scopus citations
• 2017

  Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

  Long, Y., Bolanos, B., Gong, L., Liu, W., Goodrich, K. J., Yang, X., Chen, S., Gooding, A. R., Maegley, K. A., Gajiwala, K. S., Brooun, A., Cech, T. R. & Liu, X., Nov 29 2017, In: eLife. 6, e31558.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polycomb Repressive Complex 2 100%
  • Histone 69%
  • Lysine 61%
  • Deuterium(.) 58%
  • Mutation 55%
  68 Scopus citations

• Dynamic change of transcription pausing through modulating NELF protein stability regulates granulocytic differentiation

  Liu, X., Gogate, A. A., Tastemel, M., Malladi, V. S., Yao, H., Nguyen, K., Huang, L. J. S. & Bai, X., Aug 8 2017, In: Blood Advances. 1, 18, p. 1358-1367 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • negative elongation factor 100%
  • Protein Stability 64%
  • Granulocytes 6%
  • Proteins 5%
  • Stem Cells 5%
  8 Scopus citations

• Generation and Characterization of Recombinant Antibody-like ADP-Ribose Binding Proteins

  Gibson, B. A., Conrad, L. B., Huang, D. & Kraus, W. L., Dec 5 2017, In: Biochemistry. 56, 48, p. 6305-6316 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenosine Diphosphate Ribose 100%
  • Carrier Proteins 58%
  • Antibodies 38%
  • Protein 28%
  • ADP-Ribosylation 23%
  66 Scopus citations

• Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs

  Partin, A. C., Ngo, T. D., Herrell, E., Jeong, B. C., Hon, G. & Nam, Y., Dec 1 2017, In: Nature communications. 8, 1, 1737.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MicroRNA 100%
  • microprocessors 98%
  • Heme 90%
  • positioning 80%
  • MicroRNAs 68%
  45 Scopus citations

• LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation

  Wang, L., Nam, Y., Lee, A. K., Yu, C., Roth, K., Chen, C., Ransey, E. M. & Sliz, P., Mar 14 2017, In: Cell Reports. 18, 11, p. 2664-2675 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Zinc 100%
  • MicroRNA 63%
  • UTP-RNA uridylyltransferase 54%
  • MicroRNAs 43%
  • RNA-Binding Proteins 30%
  47 Scopus citations

• Polycomb repressive complex 2 in an autoinhibited state

  Bratkowski, M., Yang, X. & Liu, X., Aug 11 2017, In: Journal of Biological Chemistry. 292, 32, p. 13323-13332 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • H3K27Me3 100%
  • Polycomb Repressive Complex 2 80%
  • Enzyme Kinetics 63%
  • Histone 56%
  • Lysine 49%
  13 Scopus citations

• Transcription pausing regulates mouse embryonic stem cell differentiation

  Tastemel, M., Gogate, A. A., Malladi, V. S., Nguyen, K., Mitchell, C., Banaszynski, L. A. & Bai, X., Dec 2017, In: Stem Cell Research. 25, p. 250-255 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mouse Embryonic Stem Cells 100%
  • Embryonic Stem Cells 86%
  • Cell Differentiation 66%
  • RNA Polymerase II 23%
  • Chromatin 17%
  10 Scopus citations
• 2016

  Data publication with the structural biology data grid supports live analysis

  Meyer, P. A., Socias, S., Key, J., Ransey, E., Tjon, E. C., Buschiazzo, A., Lei, M., Botka, C., Withrow, J., Neau, D., Rajashankar, K., Anderson, K. S., Baxter, R. H., Blacklow, S. C., Boggon, T. J., Bonvin, A. M. J. J., Borek, D., Brett, T. J., Caflisch, A., Chang, C. I., & 50 othersChazin, W. J., Corbett, K. D., Cosgrove, M. S., Crosson, S., Dhe-Paganon, S., Di Cera, E., Drennan, C. L., Eck, M. J., Eichman, B. F., Fan, Q. R., Ferré-D'Amaré, A. R., Fromme, J. C., Garcia, K. C., Gaudet, R., Gong, P., Harrison, S. C., Heldwein, E. E., Jia, Z., Keenan, R. J., Kruse, A. C., Kvansakul, M., McLellan, J. S., Modis, Y., Nam, Y., Otwinowski, Z., Pai, E. F., Pereira, P. J. B., Petosa, C., Raman, C. S., Rapoport, T. A., Roll-Mecak, A., Rosen, M. K., Rudenko, G., Schlessinger, J., Schwartz, T. U., Shamoo, Y., Sondermann, H., Tao, Y. J., Tolia, N. H., Tsodikov, O. V., Westover, K. D., Wu, H., Foster, I., Fraser, J. S., Maia, F. R. N. C., Gonen, T., Kirchhausen, T., Diederichs, K., Crosas, M. & Sliz, P., Mar 7 2016, In: Nature communications. 7, 10882.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • biology 100%
  • Publications 78%
  • grids 76%
  • Datasets 74%
  • biomedical data 60%
  97 Scopus citations

• Developing EZH2-targeted therapy for lung cancer

  Frankel, A. E., Liu, X. & Minna, J. D., Sep 2016, In: Cancer discovery. 6, 9, p. 949-952 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenocarcinoma of Lung 100%
  • Drug Discovery 96%
  • Epigenomics 81%
  • Lung Neoplasms 74%
  • In Vitro Techniques 40%
  24 Scopus citations

• HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing

  Liu, H., Liang, C., Kollipara, R. K., Matsui, M., Ke, X., Jeong, B. C., Wang, Z., Yoo, K. S., Yadav, G. P., Kinch, L. N., Grishin, N. V., Nam, Y., Corey, D. R., Kittler, R. & Liu, Q., Aug 4 2016, In: Molecular cell. 63, 3, p. 420-432 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chromatin 100%
  • MicroRNAs 95%
  • Microcomputers 24%
  • Chromatin Immunoprecipitation 11%
  • Histones 9%
  26 Scopus citations

• Response to comment on "structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2"

  Jiao, L. & Liu, X., Dec 23 2016, In: Science. 354, 6319, p. 1543 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  7 Scopus citations

• RNA polymerase II pausing modulates hematopoietic stem cell emergence in zebrafish

  Yang, Q., Liu, X., Zhou, T., Cook, J., Nguyen, K. & Bai, X., Sep 29 2016, In: Blood. 128, 13, p. 1701-1710 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Polymerase II 100%
  • Effector 93%
  • Zebrafish 87%
  • Hematopoietic Stem Cells 85%
  • Reduction 38%
  21 Scopus citations

• Structural analysis of an active fungal PRC2

  Jiao, L. & Liu, X., May 3 2016, In: Nucleus. 7, 3, p. 284-291 8 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Polycomb Repressive Complex 2 100%
  • Chaetomium 18%
  • Fungal Structures 17%
  • PR-SET Domains 16%
  • Histone Methyltransferases 14%
  7 Scopus citations

• Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

  Wang, P., Doxtader, K. A. & Nam, Y., Jul 21 2016, In: Molecular cell. 63, 2, p. 306-317 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methyltransferases 100%
  • N(6)-methyladenosine 35%
  • S-Adenosylhomocysteine 34%
  • S-Adenosylmethionine 29%
  • Adenosine 22%
  775 Scopus citations
• 2015

  Blood Induction and Embryonic Formation

  Bai, X. & Zon, L. I., 2015, Principles of Developmental Genetics: Second Edition. Elsevier Inc., p. 451-467 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Embryonic Induction 100%
  • Hematopoiesis 63%
  • Wave 53%
  • Hematopoietic Stem Cells 28%
  • Vertebrates 25%

• Ready, pause, go: Regulation of RNA polymerase II pausing and release by cellular signaling pathways

  Liu, X., Kraus, W. L. & Bai, X., Sep 1 2015, In: Trends in biochemical sciences. 40, 9, p. 516-525 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • RNA Polymerase II 100%
  • Protein 35%
  • Genes 34%
  • Proteins 31%
  • Molecule 29%
  102 Scopus citations

• Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2

  Jiao, L. & Liu, X., Oct 16 2015, In: Science. 350, 6258, aac4383.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polycomb Repressive Complex 2 100%
  • Histones 61%
  • Chaetomium 37%
  • PR-SET Domains 33%
  • Peptides 27%
  280 Scopus citations
• 2014

  Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2

  Kong, X., Chen, L., Jiao, L., Jiang, X., Lian, F., Lu, J., Zhu, K., Du, D., Liu, J., Ding, H., Zhang, N., Shen, J., Zheng, M., Chen, K., Liu, X., Jiang, H. & Luo, C., Nov 26 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9512-9521 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Astemizole 100%
  • Polycomb Repressive Complex 2 86%
  • Cell Proliferation 37%
  • H3K27Me3 36%
  • Histone 20%
  87 Scopus citations

• Catalytic mechanism of histone acetyltransferase p300: From the proton transfer to acetylation reaction

  Zhang, X., Ouyang, S., Kong, X., Liang, Z., Lu, J., Zhu, K., Zhao, D., Zheng, M., Jiang, H., Liu, X., Marmorstein, R. & Luo, C., Feb 27 2014, In: Journal of Physical Chemistry B. 118, 8, p. 2009-2019 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proton transfer 100%
  • Acetylation 94%
  • acetylation 94%
  • Molecular dynamics 61%
  • Histone 59%
  28 Scopus citations
• 2013

  Architecture of an RNA polymerase II transcription pre-initiation complex

  Murakami, K., Elmlund, H., Kalisman, N., Bushnell, D. A., Adams, C. M., Azubel, M., Elmlund, D., Levi-Kalisman, Y., Liu, X., Gibbons, B. J., Levitt, M. & Kornberg, R. D., 2013, In: Science. 342, 6159, 1238724.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • General Transcription Factors 100%
  • RNA Polymerase II 78%
  • DNA Polymerase II 53%
  • Mass Spectrometry 30%
  • Electron Microscopy 28%
  136 Scopus citations

• Formation and fate of a complete 31-protein RNA polymerase II transcription preinitiation complex

  Murakami, K., Calero, G., Brown, C. R., Liu, X., Davis, R. E., Boeger, H. & Kornberg, R. D., Mar 1 2013, In: Journal of Biological Chemistry. 288, 9, p. 6325-6332 8 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Polymerase II 100%
  • General Transcription Factors 63%
  • Psoralen 60%
  • Ficusin 60%
  • TATA Box 55%
  25 Scopus citations

• RNA polymerase II transcription: Structure and mechanism

  Liu, X., Bushnell, D. A. & Kornberg, R. D., Jan 2013, In: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • General Transcription Factors 100%
  • RNA Polymerase II 78%
  • Transcription Factor TFIIB 35%
  • RNA 15%
  99 Scopus citations

• TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes

  Bai, X., Trowbridge, J. J., Riley, E., Lee, J. A., DiBiase, A., Kaartinen, V. M., Orkin, S. H. & Zon, L. I., Jan 15 2013, In: Developmental Biology. 373, 2, p. 422-430 9 p.

  Research output: Contribution to journal › Article › peer-review

  • transcriptional intermediary factor 1 100%
  • Hematopoiesis 59%
  • Erythropoiesis 31%
  • Genes 21%
  • Bone Marrow 13%
  35 Scopus citations
• 2012

  A grid-enabled web service for low-resolution crystal structure refinement

  Odonovan, D. J., Stokes-Rees, I., Nam, Y., Blacklow, S. C., Schröder, G. F., Brunger, A. T. & Sliz, P., Mar 2012, In: Acta Crystallographica Section D: Biological Crystallography. 68, 3, p. 261-267 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Running 100%
  • Datasets 75%
  • X-Rays 73%
  15 Scopus citations

• Conformational locking upon cooperative assembly of notch transcription complexes

  Choi, S. H., Wales, T. E., Nam, Y., O'Donovan, D. J., Sliz, P., Engen, J. R. & Blacklow, S. C., Feb 8 2012, In: Structure. 20, 2, p. 340-349 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ankyrins 100%
  • Ankyrin Repeat 67%
  • Kinetics 34%
  • DNA Probes 28%
  • Dimerization 26%
  52 Scopus citations

• Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation

  Murakami, K., Gibbons, B. J., Davis, R. E., Nagai, S., Liu, X., Robinson, P. J. J., Wu, T., Kaplan, C. D. & Kornberg, R. D., Mar 27 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 13, p. 4816-4821 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription Factor TFIIH 100%
  • General Transcription Factors 88%
  • DNA Helicases 83%
  • Factor V 76%
  • Cell Nucleus Active Transport 70%
  20 Scopus citations
• 2011

  Genetic suppressor screens in haploids

  Bai, X., Yang, Z., Jiang, H., Lin, S. & Zon, L. I., 2011, In: Methods in Cell Biology. 104, p. 129-136 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Haploidy 100%
  • Zebrafish 80%
  • Vertebrates 23%
  • Phenotype 15%
  • Erythropoiesis 15%
  2 Scopus citations

• Initiation complex structure and promoter proofreading

  Liu, X., Bushnell, D. A., Silva, D. A., Huang, X. & Kornberg, R. D., Jul 29 2011, In: Science. 333, 6042, p. 633-637 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA 100%
  • Nucleotides 58%
  • RNA Polymerase II 27%
  • X-Rays 18%
  • DNA 13%
  49 Scopus citations

• Lock and key to transcription: σ-DNA interaction

  Liu, X., Bushnell, D. A. & Kornberg, R. D., Dec 9 2011, In: Cell. 147, 6, p. 1218-1219 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • DNA 100%
  • DNA-Directed RNA Polymerases 99%
  • Crystal Structure 88%
  • RNA 62%
  19 Scopus citations

• Molecular basis for interaction of let-7 MicroRNAs with Lin28

  Nam, Y., Chen, C., Gregory, R. I., Chou, J. J. & Sliz, P., Nov 23 2011, In: Cell. 147, 5, p. 1080-1091 12 p.

  Research output: Contribution to journal › Article › peer-review

  • MicroRNA 100%
  • MicroRNAs 68%
  • RNA 56%
  • Small Untranslated RNA 49%
  • Psychology Recognition 35%
  299 Scopus citations

• Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation

  Aster, J. C., Bodnar, N., Xu, L., Karnell, F., Milholland, J. M., Maillard, I., Histen, G., Nam, Y., Blacklow, S. C. & Pear, W. S., Oct 13 2011, In: PloS one. 6, 10, e25645.

  Research output: Contribution to journal › Article › peer-review

  • Ankyrin Repeat 100%
  • ankyrins 99%
  • transcriptional activation 77%
  • lymphocytic leukemia 68%
  • T-lymphocytes 63%
  8 Scopus citations

• Structure of human O-GlcNAc transferase and its complex with a peptide substrate

  Lazarus, M. B., Nam, Y., Jiang, J., Sliz, P. & Walker, S., Jan 27 2011, In: Nature. 469, 7331, p. 564-569 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • O-GlcNAc transferase 100%
  • Uridine Diphosphate N-Acetylglucosamine 99%
  • Uridine Diphosphate 79%
  • UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase 54%
  • Protamine Kinase 51%
  354 Scopus citations
• 2010

  Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism

  Liu, X., Bushnell, D. A., Wang, D., Calero, G. & Kornbergt, R. D., 2010, In: Science. 327, 5962, p. 206-209 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription Factor TFIIB 100%
  • RNA Polymerase II 73%
  • General Transcription Factors 62%
  • Fingers 38%
  • X-Rays 16%
  166 Scopus citations

• TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation

  Bai, X., Kim, J., Yang, Z., Jurynec, M. J., Akie, T. E., Lee, J., LeBlanc, J., Sessa, A., Jiang, H., DiBiase, A., Zhou, Y., Grunwald, D. J., Lin, S., Cantor, A. B., Orkin, S. H. & Zon, L. I., Jul 2010, In: Cell. 142, 1, p. 133-143 11 p.

  Research output: Contribution to journal › Article › peer-review

  • transcriptional intermediary factor 1 100%
  • Erythroid Cells 68%
  • Peptide Elongation Factors 49%
  • Genes 21%
  • RNA Polymerase II 21%
  176 Scopus citations
• 2008

  A role for the two-helix finger of the SecA ATPase in protein translocation

  Erlandson, K. J., Miller, S. B. M., Nam, Y., Osborne, A. R., Zimmer, J. & Rapoport, T. A., Oct 16 2008, In: Nature. 455, 7215, p. 984-987 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Transport 100%
  • Adenosine Triphosphatases 90%
  • Fingers 82%
  • Peptides 57%
  • Tyrosine 55%
  107 Scopus citations