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2019
Open Access

Selective targeting of myoblast fusogenic signaling and differentiation-arrest antagonizes rhabdomyosarcoma cells

Granados, V. A., Avirneni-Vadlamudi, U., Dalal, P., Scarborough, S. R., Galindo, K. A., Mahajan, P. & Galindo, R. L., Sep 15 2019, In : Cancer Research. 79, 18, p. 4585-4591 7 p.

Research output: Contribution to journalArticle

2016

Hepatology after Hepatitis C

Fitz, J. G., Jun 1 2016, In : Digestive Diseases. 34, 5, p. 603-606 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2 Scopus citations
2015

A rapid one-generation genetic screen in a drosophila model to capture rhabdomyosarcoma effectors and therapeutic targets

Galindo, K. A., Endicott, T. R., Avirneni-Vadlamudi, U. & Galindo, R. L., Jan 1 2015, In : G3: Genes, Genomes, Genetics. 5, 2, p. 205-217 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
8 Scopus citations

PAX genes in childhood oncogenesis: Developmental biology gone awry?

Mahajan, P., Leavey, P. J. & Galindo, R. L., May 21 2015, In : Oncogene. 34, 21, p. 2681-2689 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Probing for a deeper understanding of rhabdomyosarcoma: Insights from complementary model systems

Kashi, V. P., Hatley, M. E. & Galindo, R. L., Jul 26 2015, In : Nature Reviews Cancer. 15, 7, p. 426-439 14 p.

Research output: Contribution to journalArticle

46 Scopus citations
2014

Alveolar rhabdomyosarcoma-Associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

Crose, L. E. S., Galindo, K. A., Kephart, J. G., Chen, C., Fitamant, J., Bardeesy, N., Bentley, R. C., Galindo, R. L., Ashley Chi, J. T. & Linardic, C. M., Jan 2 2014, In : Journal of Clinical Investigation. 124, 1, p. 285-296 12 p.

Research output: Contribution to journalArticle

66 Scopus citations
2012

A Mouse Model of Rhabdomyosarcoma Originating from the Adipocyte Lineage

Hatley, M. E., Tang, W., Garcia, M. R., Finkelstein, D., Millay, D. P., Liu, N., Graff, J., Galindo, R. L. & Olson, E. N., Oct 16 2012, In : Cancer Cell. 22, 4, p. 536-546 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Drosophila and mammalian models uncover a role for the myoblast fusion gene TANC1 in rhabdomyosarcoma

Avirneni-Vadlamudi, U., Galindo, K. A., Endicott, T. R., Paulson, V., Cameron, S. & Galindo, R. L., Jan 3 2012, In : Journal of Clinical Investigation. 122, 1, p. 403-407 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: Role of nonstructural component 5A and CCAAT/enhancer-binding protein β

Qadri, I., Choudhury, M., Rahman, S. M., Knotts, T. A., Janssen, R. C., Schaack, J., Iwahashi, M., Puljak, L., Simon, F. R., Kilic, G., Fitz, G. & Friedman, J. E., Oct 26 2012, In : Journal of Biological Chemistry. 287, 44, p. 37340-37351 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Foreword

Gregory Fitz, J., Oct 31 2011, In : Unknown Journal.

Research output: Contribution to journalArticle

High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis

Paulson, V., Chandler, G., Rakheja, D., Galindo, R. L., Wilson, K. S., Amatruda, J. F. & Cameron, S., Jun 1 2011, In : Genes Chromosomes and Cancer. 50, 6, p. 397-408 12 p.

Research output: Contribution to journalArticle

73 Scopus citations
2010

Copper inhibits P2Y2-dependent Ca2+ signaling through the effects on thapsigargin-sensitive Ca2+ stores in HTC hepatoma cells

Dolovcak, S., Waldrop, S. L., Fitz, J. G. & Kilic, G., Jul 1 2010, In : Biochemical and Biophysical Research Communications. 397, 3, p. 493-498 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Initiation of purinergic signaling by exocytosis of ATP-containing vesicles in liver epithelium

Feranchak, A. P., Lewis, M. A., Kresge, C., Sathe, M., Bugde, A., Luby-Phelps, K., Antich, P. P. & Fitz, J. G., Mar 12 2010, In : Journal of Biological Chemistry. 285, 11, p. 8138-8147 10 p.

Research output: Contribution to journalArticle

52 Scopus citations
2009

5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) stimulates cellular ATP release through exocytosis of ATP-enriched vesicles

Dolovcak, S., Waldrop, S. L., Fitz, J. G. & Kilic, G., Dec 4 2009, In : Journal of Biological Chemistry. 284, 49, p. 33894-33903 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Report of the Multisociety Task Force on GI Training

Friedman, L. S., Brandt, L. J., Elta, G. H., Fitz, J. G., Gores, G. J., Katz, P. O., Kuemmerle, J. F., Pardi, D. S., Vargo, J. J. & Stolar, M. H., Dec 1 2009, In : Hepatology. 50, 5, p. 1325-1329 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Report of the Multisociety Task Force on GI Training

Friedman, L. S., Brandt, L. J., Elta, G. H., Fitz, J. G., Gores, G. J., Katz, P. O., Kuemmerle, J. F., Pardi, D. S., Vargo, J. J. & Stolar, M. H., Nov 2009, In : Gastroenterology. 137, 5, p. 1839-1843 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Report of the Multisociety Task Force on GI Training

Friedman, L. S., Brandt, L. J., Elta, G. H., Fitz, J. G., Gores, G. J., Katz, P. O., Kuemmerle, J. F., Pardi, D. S., Vargo, J. J. & Stolar, M. H., Nov 1 2009, In : Gastrointestinal endoscopy. 70, 5, p. 823-827 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008

Characterization of ionotrophic purinergic receptors in hepatocytes

Emmett, D. S., Feranchak, A., Kilic, G., Puljak, L., Miller, B., Dolovcak, S., McWilliams, R., Doctor, R. B. & Fitz, J. G., Feb 1 2008, In : Hepatology. 47, 2, p. 698-705 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line

Puljak, L., Parameswara, V., Dolovcak, S., Waldrop, S. L., Emmett, D., Esser, V., Fitz, J. G. & Kilic, G., Jun 10 2008, In : Experimental Cell Research. 314, 10, p. 2100-2109 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Extracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ release

Dutta, A. K., Woo, K., Doctor, R. B., Fitz, J. G. & Feranchak, A. P., Nov 1 2008, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 295, 5, p. G1004-G1015

Research output: Contribution to journalArticle

28 Scopus citations
2007

Regulated ion transport in mouse liver cyst epithelial cells

Doctor, R. B., Johnson, S., Brodsky, K. S., Amura, C. R., Gattone, V. & Fitz, J. G., Mar 1 2007, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1772, 3, p. 345-354 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR

Galindo, R. L., Allport, J. A. & Olson, E. N., Sep 5 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 36, p. 13439-13444 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Sialoblastoma: A rare submandibular gland neoplasm

Verret, D. J., Galindo, R. L., DeFatta, R. J. & Bauer, P. W., Jul 1 2006, In : Ear, Nose and Throat Journal. 85, 7, p. 440-442 3 p.

Research output: Contribution to journalArticle

10 Scopus citations
2005

Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance

Puljak, L., Pagliassotti, M. J., Wei, Y., Qadri, I., Parameswara, V., Esser, V., Fitz, J. G. & Kilic, G., Mar 1 2005, In : Journal of Physiology. 563, 2, p. 471-482 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Purinergic regulation of cholangiocyte secretion: Identification of a novel role for P2X receptors

Doctor, R. B., Matzakos, T., McWilliams, R., Johnson, S., Feranchak, A. P. & Fitz, J. G., Apr 1 2005, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 288, 4 51-4, p. G779-G786

Research output: Contribution to journalArticle

48 Scopus citations
2004

Calcium-dependent regulation of secretion in biliary epithelial cells: The role of apamin-sensitive SK channels

Feranchak, A. P., Doctor, R. B., Troetsch, M., Brookman, K., Johnson, S. M. & Fitz, J. G., Sep 2004, In : Gastroenterology. 127, 3, p. 903-913 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid

Nichols, M. T., Gidey, E., Matzakos, T., Dahl, R., Stiegmann, G., Shah, R. J., Grantham, J. J., Fitz, J. G. & Doctor, R. B., Oct 2004, In : Hepatology. 40, 4, p. 836-846 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Vesicular exocytosis contributes to volume-sensitive ATP release in biliary cells

Gatof, D., Kilic, G. & Fitz, J. G., Apr 1 2004, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 286, 4 49-4, p. G538-G546

Research output: Contribution to journalArticle

62 Scopus citations

Water induces autocrine stimulation of tumor cell killing through ATP release and P2 receptor binding

Selzner, N., Selzner, M., Graf, R., Ungethuem, U., Fitz, J. G. & Clavien, P. A., Jan 1 2004, In : Cell Death and Differentiation. 11, p. S172-S180

Research output: Contribution to journalArticle

29 Scopus citations
2003

Giant fibrovascular polyp of the esophagus: A lesion causing upper airway obstruction and syncope

Fries, M. R., Galindo, R. L., Flint, P. W. & Abraham, S. C., Apr 1 2003, In : Archives of Pathology and Laboratory Medicine. 127, 4, p. 485-487 3 p.

Research output: Contribution to journalArticle

29 Scopus citations

Solitary fibrous tumor of the thyroid: Cytopathologic findings and differential diagnosis

Parwani, A. V., Galindo, R., Steinberg, D. M., Zeiger, M. A., Westra, W. H. & Ali, S. Z., Apr 1 2003, In : Diagnostic cytopathology. 28, 4, p. 213-216 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Volume-sensitive Tyrosine Kinases Regulate Liver Cell Volume through Effects on Vesicular Trafficking and Membrane Na+ Permeability

Feranchak, A. P., Kilic, G., Wojtaszek, P. A., Qadri, I. & Fitz, J. G., Nov 7 2003, In : Journal of Biological Chemistry. 278, 45, p. 44632-44638 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2002

Cholangiocytes exhibit dynamic, actin-dependent apical membrane turnover

Brian Doctor, R., Dahl, R., Fouassier, L., Kilic, G. & Gregory Fitz, J., Jul 2 2002, In : American Journal of Physiology - Cell Physiology. 282, 5 51-5, p. C1042-C1052

Research output: Contribution to journalArticle

32 Scopus citations
11 Scopus citations

Molecular characterization of volume-sensitive SKCa channels in human liver cell lines

Roman, R., Feranchak, A. P., Troetsch, M., Dunkelberg, J. C., Kilic, G., Schlenker, T., Schaack, J. & Gregory Fitz, J., Jun 27 2002, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 282, 1 45-1, p. G116-G122

Research output: Contribution to journalArticle

36 Scopus citations
2001

ClC-2 chloride channels contribute to HTC cell volume homeostasis

Roman, R. M., Smith, R. L., Feranchak, A. P., Clayton, G. H., Doctor, R. B. & Fitz, J. G., Mar 1 2001, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 280, 3 43-3, p. G344-G353

Research output: Contribution to journalArticle

45 Scopus citations

Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation

Braunstein, G. M., Roman, R. M., Clancy, J. P., Kudlow, B. A., Taylor, A. L., Shylonsky, V. G., Jovov, B., Peter, K., Jilling, T., Ismailov, I. I., Benos, D. J., Schwiebert, L. M., Fitz, J. G. & Schwiebert, E. M., Mar 2 2001, In : Journal of Biological Chemistry. 276, 9, p. 6621-6630 10 p.

Research output: Contribution to journalArticle

159 Scopus citations

Evidence for multidrug resistance-1 P-glycoprotein-dependent regulation of cellular ATP permeability

Roman, R. M., Lomri, N., Braunstein, G., Feranchak, A. P., Simeoni, L. A., Davison, A. K., Mechetner, E., Schwiebert, E. M. & Fitz, J. G., Oct 1 2001, In : Journal of Membrane Biology. 183, 3, p. 165-173 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Ezrin-radixin-moesin-binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia

Fouassier, L., Cheng Ying Duan, Y. D., Feranchak, A. P., Yun, C. H. C., Sutherland, E., Simon, F., Fitz, J. G. & Doctor, R. B., Jan 1 2001, In : Hepatology. 33, 1, p. 166-176 11 p.

Research output: Contribution to journalArticle

84 Scopus citations
28 Scopus citations

Liver cell volume regulation: Size matters

Dunkelberg, J. C., Feranchak, A. P. & Fitz, J. G., Jan 1 2001, In : Hepatology. 33, 6, p. 1349-1352 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability

Feranchak, A. P., Berl, T., Capasso, J., Wojtaszek, P. A., Han, J. & Fitz, J. G., Dec 8 2001, In : Journal of Clinical Investigation. 108, 10, p. 1495-1504 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Regulation of biliary secretion by extracellular nucleotides

Feranchak, A. P. & Gregory Fitz, J., May 15 2001, In : Drug Development Research. 52, 1-2, p. 232-238 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2000

ATP depletion in rat cholangiocytes leads to marked internalization of membrane proteins

Doctor, R. B., Dahl, R. H., Salter, K. D., Fouassier, L., Chen, J. & Fitz, J. G., Jan 1 2000, In : Hepatology. 31, 5, p. 1045-1054 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Domain-specific purinergic signaling in polarized rat cholangiocytes

Salter, K. D., Fitz, J. G. & Roman, R. M., Mar 1 2000, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 278, 3 41-3, p. G492-G500

Research output: Contribution to journalArticle

42 Scopus citations

Evidence for ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions

Fouassier, L., Yun, C. C., Fitz, J. G. & Doctor, R. B., Aug 11 2000, In : Journal of Biological Chemistry. 275, 32, p. 25039-25045 7 p.

Research output: Contribution to journalArticle

98 Scopus citations