Office of the President - Administration

Research Output

2019

Kurt J. Isselbacher, MD (1925–2019)

Friedman, L. S. & Podolsky, D. K., Nov 2019, In : Gastroenterology. 157, 5, p. 1173-1174 2 p.

Research output: Contribution to journalEditorial

Open Access
2018

Colonic glycoprotein heterogeneity in the cotton-top tamarin: Glycoconjugate modifications associated with the nonhuman primate model of inflammatory bowel disease and colonic cancer

Boland, C. R. & Podolsky, D. K., Jan 1 2018, A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus). CRC Press, p. 267-282 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Scintigraphic imaging of tamarin colorectal carcinoma with radiolabeled monoclonal antibodies

Crook, J. E. & Podolsky, D. K., Jan 1 2018, A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus). CRC Press, p. 309-316 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Foreword

Podolsky, D. K., Mar 1 2017, Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach: Second Edition. Springer International Publishing, p. v-vi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCϵ-dependent Pathway

Wei, S. C., Yang-Yen, H. F., Tsao, P. N., Weng, M. T., Tung, C. C., Yu, L. C. H., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Ni, Y. H., Xavier, R. J., Podolsky, D. K., Yen, J. J. Y. & Wong, J. M., Oct 1 2017, In : Inflammatory Bowel Diseases. 23, 10, p. 1730-1740 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Gastroenterology, Academic Medicine and a Changing Landscape

Podolsky, D. K., Sep 23 2015, In : Digestive Diseases. 33, p. 57-60 4 p.

Research output: Contribution to journalArticle

Reflections on mentorship on the occasion of Dr Kurt J. Isselbacher's 90th birthday

Podolsky, D. K., Aug 1 2015, In : Gastroenterology. 149, 2, p. 268-269 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Texas medical center keeps its focus on process improvement

Podolsky, D. & Kutscher, B., Jul 27 2015, In : Modern Healthcare. 45, 30, p. 30-31 2 p.

Research output: Contribution to journalArticle

2014

Public reporting of patient safety metrics: Ready or not?

Podolsky, D. K., Nagarkar, P. A., Reed, W. G. & Rohrich, R. J., Jan 1 2014, In : Plastic and reconstructive surgery. 134, 6, p. 981e-985e

Research output: Contribution to journalArticle

2 Scopus citations

SLCO3A1, a novel Crohn's disease-associated gene, regulates NF-κB activity and associates with intestinal perforation

Wei, S. C., Tan, Y. Y., Weng, M. T., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Wu, D. C., Kao, A. W., Chuang, C. S., Ni, Y. H., Shieh, M. J., Tung, C. C., Chen, Y., Wang, C. Y., Xavier, R. J., Podolsky, D. K. & Wong, J. M., Jun 19 2014, In : PloS one. 9, 6, e100515.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships.

Fordtran, J. S., Goyal, R. K., Feldman, M., Soll, A. H., Trier, J. S., Ockner, R. K., Larusso, N. F., Podolsky, D. K., Brenner, D. A., Rustgi, A. K. & Omary, M. B., Jul 2013, In : Gastroenterology. 145, 1, p. 16-31 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier

Müller, T., Beutler, C., Picó, A. H., Otten, M., Dürr, A., Al-Abadi, H., Guckelberger, O., Meyer Zum Büschenfelde, D., Jöhrens, K., Volkmann, M., Lankisch, T., Voigtländer, T., Anders, M., Shibolet, O., Jefferson, D. M., Podolsky, D. K., Fischer, A., Veltzke-Schlieker, W., Adler, A., Baumgart, D. C. & 4 others, Sturm, A., Wiedenmann, B., Schott, E. & Berg, T., May 2013, In : Gastroenterology. 144, 5, p. 1116-1128 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Kenji Fujiwara, MD, PhD.

Sugano, K., Podolsky, D. K., Brenner, D. A., Michalopoulos, G. & Tsukamoto, H., Apr 2013, In : Unknown Journal. 144, 4, p. 661-663 3 p.

Research output: Contribution to journalArticle

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis

Ey, B., Eyking, A., Klepak, M., Salzman, N. H., Göthert, J. R., Run̈zi, M., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5676-5688 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Foreword

Podolsky, D. K., Jan 1 2012, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

Forward

Podolsky, D. K., Jan 4 2012, In : Unknown Journal.

Research output: Contribution to journalArticle

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling

Wei, S. C., Rosenberg, I. M., Cao, Z., Huett, A. S., Xavier, R. J. & Podolsky, D. K., May 1 2012, In : Inflammatory bowel diseases. 18, 5, p. 877-888 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis

Mueller, T., Beutler, C., Picó, A. H., Shibolet, O., Pratt, D. S., Pascher, A., Neuhaus, P., Wiedenmann, B., Berg, T. & Podolsky, D. K., Nov 1 2011, In : Liver International. 31, 10, p. 1574-1588 15 p.

Research output: Contribution to journalArticle

53 Scopus citations

Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer

Eyking, A., Ey, B., Rünzi, M., Roig, A. I., Reis, H., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Dec 2011, In : Gastroenterology. 141, 6, p. 2154-2165 12 p.

Research output: Contribution to journalArticle

59 Scopus citations
2010

Biological Basis of Healing and Repair in Remission and Relapse

Playford, R. J. & Podolsky, D. K., May 18 2010, Inflammatory Bowel Disease: Translating basic science into clinical practice. Wiley-Blackwell, p. 170-181 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3

Beck, P. L., Ihara, E., Hirota, S. A., MacDonald, J. A., Meng, D., Nanthakumar, N. N., Podolsky, D. K. & Xavier, R. J., Jul 1 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 1, p. G43-G53

Research output: Contribution to journalArticle

17 Scopus citations

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Surolia, I., Pirnie, S. P., Chellappa, V., Taylor, K. N., Cariappa, A., Moya, J., Liu, H., Bell, D. W., Driscoll, D. R., Diederichs, S., Haider, K., Netravali, I., Le, S., Elia, R., Dow, E., Lee, A., Freudenberg, J., De Jager, P. L., Chretien, Y., Varki, A. & 13 others, MacDonald, M. E., Gillis, T., Behrens, T. W., Bloch, D., Collier, D., Korzenik, J., Podolsky, D. K., Hafler, D., Murali, M., Sands, B., Stone, J. H., Gregersen, P. K. & Pillai, S., Jul 8 2010, In : Nature. 466, 7303, p. 243-247 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Identification of Drosophila yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters

Charrière, G. M., Ip, W. K. E., Dejardin, S., Boyer, L., Sokolovska, A., Cappillino, M. P., Cherayil, B. J., Podolsky, D. K., Kobayashi, K. S., Silverman, N., Lacy-Hulbert, A. & Stuart, L. M., Jun 25 2010, In : Journal of Biological Chemistry. 285, 26, p. 20147-20154 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

In vivo action of trefoil factor 2 (TFF2) to speed gastric repair is independent of cyclooxygenase

Xue, L., Aihara, E., Podolsky, D. K., Wang, T. C. & Montrose, M. H., Sep 2010, In : Gut. 59, 9, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

LRRK2 is involved in the IFN-γ response and host response to pathogens

Gardet, A., Benita, Y., Li, C., Sands, B. E., Ballester, I., Stevens, C., Korzenik, J. R., Rioux, J. D., Daly, M. J., Xavier, R. J. & Podolsky, D. K., Nov 1 2010, In : Journal of Immunology. 185, 9, p. 5577-5585 9 p.

Research output: Contribution to journalReview article

203 Scopus citations

MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function

Yamamoto-Furusho, J. K., Barnich, N., Hisamatsu, T. & Podolsky, D. K., Apr 16 2010, In : Inflammatory bowel diseases. 16, 5, p. 736-742 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Synthesis of biologically active biotinylated muramyl dipeptides

Grimes, C. L., Podolsky, D. K. & O'Shea, E. K., Oct 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6061-6063 3 p.

Research output: Contribution to journalArticle

14 Scopus citations
2009

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy

Huett, A., Ng, A., Cao, Z., Kuballa, P., Komatsu, M., Daly, M. J., Podolsky, D. K. & Xavier, R. J., Apr 15 2009, In : Journal of Immunology. 182, 8, p. 4917-4930 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Beyond tumor necrosis factor: Next-generation biologic therapy for inflammatory bowel disease

Podolsky, D. K., Oct 19 2009, In : Digestive Diseases. 27, 3, p. 366-369 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency

Podolsky, D. K., Gerken, G., Eyking, A. & Cario, E., Jul 2009, In : Gastroenterology. 137, 1, p. 209-220 12 p.

Research output: Contribution to journalArticle

143 Scopus citations

Development of the Gastrointestinal System

Stanger, B. Z. & Podolsky, D. K., Feb 17 2009, Textbook of Gastroenterology, Fifth Edition. Blackwell Publishing Ltd, Vol. 1. p. 567-602 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Editorial introductions

Podolsky, D. K., Cohen, M. & Bresalier, R., Jan 1 2009, In : Current Opinion in Gastroenterology. 25, 1

Research output: Contribution to journalEditorial

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

Huett, A., Leong, J. M., Podolsky, D. K. & Xavier, R. J., Jul 15 2009, In : Experimental Cell Research. 315, 12, p. 2001-2011 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury

Ey, B., Eyking, A., Gerken, G., Podolsky, D. K. & Cario, E., Aug 14 2009, In : Journal of Biological Chemistry. 284, 33, p. 22332-22343 12 p.

Research output: Contribution to journalArticle

77 Scopus citations
2008

Editorial introductions

Podolsky, D. K., Boedeker, E. C. & Bresalier, R. S., Jan 1 2008, In : Current Opinion in Gastroenterology. 24, 1, p. vii-viii

Research output: Contribution to journalEditorial

Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds

Paulsen, F. P., Woon, C. W., Varoga, D., Jansen, A., Garreis, F., Jäger, K., Amm, M., Podolsky, D. K., Steven, P., Barker, N. P. & Sel, S., May 9 2008, In : Journal of Biological Chemistry. 283, 19, p. 13418-13427 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

TNF Receptor Type I-Dependent Activation of Innate Responses to Reduce Intestinal Damage-Associated Mortality

Mizoguchi, E., Hachiya, Y., Kawada, M., Nagatani, K., Ogawa, A., Sugimoto, K., Mizoguchi, A. & Podolsky, D. K., Feb 2008, In : Gastroenterology. 134, 2, p. 470-480 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling

Shibolet, O., Giallourakis, C., Rosenberg, I., Mueller, T., Xavier, R. J. & Podolsky, D. K., Nov 30 2007, In : Journal of Biological Chemistry. 282, 48, p. 35308-35317 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Editorial introductions

Podolsky, D. K., Boedeker, E. C. & Bresalier, R. S., Jan 1 2007, In : Current Opinion in Gastroenterology. 23, 1, p. vii-viii

Research output: Contribution to journalEditorial

Innate immunity in inflammatory bowel disease

Yamamoto-Furusho, J. K. & Podolsky, D. K., Nov 14 2007, In : World Journal of Gastroenterology. 13, 42, p. 5577-5580 4 p.

Research output: Contribution to journalArticle

66 Scopus citations

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

De Jager, P. L., Franchimont, D., Waliszewska, A., Bitton, A., Cohen, A., Langelier, D., Belaiche, J., Vermeire, S., Farwell, L., Goris, A., Libioulle, C., Jani, N., Dassopoulos, T., Bromfield, G. P., Dubois, B., Cho, J. H., Brant, S. R., Duerr, R. H., Yang, H., Rotter, J. I. & 7 others, Silverberg, M. S., Steinhart, A. H., Daly, M. J., Podolsky, D. K., Louis, E., Hafler, D. A. & Rioux, J. D., Jul 1 2007, In : Genes and Immunity. 8, 5, p. 387-397 11 p.

Research output: Contribution to journalArticle

114 Scopus citations
168 Scopus citations

Toll-Like Receptor 2 Controls Mucosal Inflammation by Regulating Epithelial Barrier Function

Cario, E., Gerken, G. & Podolsky, D. K., Apr 2007, In : Gastroenterology. 132, 4, p. 1359-1374 16 p.

Research output: Contribution to journalArticle

441 Scopus citations

Unravelling the pathogenesis of inflammatory bowel disease

Xavier, R. J. & Podolsky, D. K., Jul 26 2007, In : Nature. 448, 7152, p. 427-434 8 p.

Research output: Contribution to journalReview article

2613 Scopus citations
2006

Case 8-2006: A 71-year-old woman with Crohn's disease and altered mental status

Podolsky, D. K., Gonzalez, R. G., Hasserjian, R. P., Harris, N. L. & Hochberg, E. P., Mar 16 2006, In : New England Journal of Medicine. 354, 11, p. 1178-1184 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Centaurin β1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-κB activation

Yamamoto-Furusho, J. K., Barnich, N., Xavier, R., Hisamatsu, T. & Podolsky, D. K., Nov 24 2006, In : Journal of Biological Chemistry. 281, 47, p. 36060-36070 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Dr. Podolsky replies [11]

Podolsky, D. K., Feb 9 2006, In : New England Journal of Medicine. 354, 6, p. 644-645 2 p.

Research output: Contribution to journalLetter

Editorial introductions

Podolsky, D. K., Boedeker, E. C. & Bresalier, R. S., Jan 1 2006, In : Current Opinion in Gastroenterology. 22, 1, p. 2P

Research output: Contribution to journalEditorial

Evolving knowledge and therapy of inflammatory bowel disease

Korzenik, J. R. & Podolsky, D. K., Mar 1 2006, In : Nature Reviews Drug Discovery. 5, 3, p. 197-209 13 p.

Research output: Contribution to journalReview article

135 Scopus citations

Remission, relapse, intestinal healing and repair

Göke, M. N. & Podolsky, D. K., Dec 1 2006, Inflammatory Bowel Disease: From Bench to Bedside. Springer US, p. 197-209 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations