Research Output

2020

Current management and future treatment of alcoholic hepatitis

Mitchell, M. C., Kerr, T. A. & Franklin Herlong, H., Apr 2020, In : Gastroenterology and Hepatology. 16, 4, p. 178-189 12 p.

Research output: Contribution to journalArticle

2019

Biomarkers of Macrophage Activation and Immune Danger Signals Predict Clinical Outcomes in Alcoholic Hepatitis

Saha, B., Tornai, D., Kodys, K., Adejumo, A., Lowe, P., McClain, C., Mitchell, M., McCullough, A., Dasarathy, S., Kroll-Desrosiers, A., Barton, B., Radaeva, S. & Szabo, G., Oct 1 2019, In : Hepatology. 70, 4, p. 1134-1149 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Changing Times in Liver Transplantation for Alcohol-Associated Liver Disease

Mitchell, M. C. & Maddrey, W. C., Jan 1 2019, (Accepted/In press) In : JAMA Internal Medicine.

Research output: Contribution to journalArticle

2 Scopus citations

Kurt J. Isselbacher, MD (1925–2019)

Friedman, L. S. & Podolsky, D. K., Nov 2019, In : Gastroenterology. 157, 5, p. 1173-1174 2 p.

Research output: Contribution to journalEditorial

Open Access
2018

Colonic glycoprotein heterogeneity in the cotton-top tamarin: Glycoconjugate modifications associated with the nonhuman primate model of inflammatory bowel disease and colonic cancer

Boland, C. R. & Podolsky, D. K., Jan 1 2018, A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus). CRC Press, p. 267-282 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data From Controlled Trials

Louvet, A., Thursz, M. R., Kim, D. J., Labreuche, J., Atkinson, S. R., Sidhu, S. S., O'Grady, J. G., Akriviadis, E., Sinakos, E., Carithers, R. L., Ramond, M. J., Maddrey, W. C., Morgan, T. R., Duhamel, A. & Mathurin, P., Aug 2018, In : Gastroenterology. 155, 2, p. 458-468.e8

Research output: Contribution to journalArticle

38 Scopus citations

Food for thought: Importance of nutrition in alcoholic hepatitis

Aday, A. W. & Mitchell, M. C., Mar 2018, In : Practical Gastroenterology. 42, 3, p. 30-36 7 p.

Research output: Contribution to journalArticle

Scintigraphic imaging of tamarin colorectal carcinoma with radiolabeled monoclonal antibodies

Crook, J. E. & Podolsky, D. K., Jan 1 2018, A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus). CRC Press, p. 309-316 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Foreword

Podolsky, D. K., Mar 1 2017, Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach: Second Edition. Springer International Publishing, p. v-vi

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCϵ-dependent Pathway

Wei, S. C., Yang-Yen, H. F., Tsao, P. N., Weng, M. T., Tung, C. C., Yu, L. C. H., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Ni, Y. H., Xavier, R. J., Podolsky, D. K., Yen, J. J. Y. & Wong, J. M., Oct 1 2017, In : Inflammatory Bowel Diseases. 23, 10, p. 1730-1740 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Ribavirin Pregnancy Registry: An Interim Analysis of Potential Teratogenicity at the Mid-Point of Enrollment

Sinclair, S. M., Jones, J. K., Miller, R. K., Greene, M. F., Kwo, P. Y. & Maddrey, W. C., Jul 8 2017, (Accepted/In press) In : Drug Safety. p. 1-14 14 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Chronic Hepatitis B virus infection

Yuen, M. F., Ahn, S. H., Chen, D. S., Chen, P. J., Dusheiko, G. M., Hou, J. L., Maddrey, W. C., Mizokami, M., Seto, W. K., Zoulim, F. & Lai, C. L., 2016, In : Journal of Clinical Gastroenterology. 50, 4, p. 286-294 9 p.

Research output: Contribution to journalReview article

28 Scopus citations
2015

Gastroenterology, Academic Medicine and a Changing Landscape

Podolsky, D. K., Sep 23 2015, In : Digestive Diseases. 33, p. 57-60 4 p.

Research output: Contribution to journalArticle

Liver MRI: Correlation with other imaging modalities and histopathology, second edition

Hussain, S. M., Sorrell, M. F., Maddrey, W. C. & Semelka, R. C., Jan 1 2015, Springer International Publishing. 351 p.

Research output: Book/ReportBook

Reflections on mentorship on the occasion of Dr Kurt J. Isselbacher's 90th birthday

Podolsky, D. K., Aug 1 2015, In : Gastroenterology. 149, 2, p. 268-269 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Texas medical center keeps its focus on process improvement

Podolsky, D. & Kutscher, B., Jul 27 2015, In : Modern Healthcare. 45, 30, p. 30-31 2 p.

Research output: Contribution to journalArticle

2014

Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertension

Dingemanse, J., Sidharta, P. N., Maddrey, W. C., Rubin, L. J. & Mickail, H., Mar 1 2014, In : Expert Opinion on Drug Safety. 13, 3, p. 391-405 15 p.

Research output: Contribution to journalArticle

45 Scopus citations

Public reporting of patient safety metrics: Ready or not?

Podolsky, D. K., Nagarkar, P. A., Reed, W. G. & Rohrich, R. J., Jan 1 2014, In : Plastic and reconstructive surgery. 134, 6, p. 981e-985e

Research output: Contribution to journalArticle

2 Scopus citations

SLCO3A1, a novel Crohn's disease-associated gene, regulates NF-κB activity and associates with intestinal perforation

Wei, S. C., Tan, Y. Y., Weng, M. T., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Wu, D. C., Kao, A. W., Chuang, C. S., Ni, Y. H., Shieh, M. J., Tung, C. C., Chen, Y., Wang, C. Y., Xavier, R. J., Podolsky, D. K. & Wong, J. M., Jun 19 2014, In : PloS one. 9, 6, e100515.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Clinical manifestations and management of drug-induced liver diseases

Maddrey, W. C., Aug 27 2013, Drug-Induced Liver Disease. Elsevier Inc., p. 229-240 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships.

Fordtran, J. S., Goyal, R. K., Feldman, M., Soll, A. H., Trier, J. S., Ockner, R. K., Larusso, N. F., Podolsky, D. K., Brenner, D. A., Rustgi, A. K. & Omary, M. B., Jul 2013, In : Gastroenterology. 145, 1, p. 16-31 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier

Müller, T., Beutler, C., Picó, A. H., Otten, M., Dürr, A., Al-Abadi, H., Guckelberger, O., Meyer Zum Büschenfelde, D., Jöhrens, K., Volkmann, M., Lankisch, T., Voigtländer, T., Anders, M., Shibolet, O., Jefferson, D. M., Podolsky, D. K., Fischer, A., Veltzke-Schlieker, W., Adler, A., Baumgart, D. C. & 4 others, Sturm, A., Wiedenmann, B., Schott, E. & Berg, T., May 2013, In : Gastroenterology. 144, 5, p. 1116-1128 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Kenji Fujiwara, MD, PhD.

Sugano, K., Podolsky, D. K., Brenner, D. A., Michalopoulos, G. & Tsukamoto, H., Apr 2013, In : Unknown Journal. 144, 4, p. 661-663 3 p.

Research output: Contribution to journalArticle

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis

Ey, B., Eyking, A., Klepak, M., Salzman, N. H., Göthert, J. R., Run̈zi, M., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5676-5688 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Foreword

Podolsky, D. K., Jan 1 2012, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

Forward

Podolsky, D. K., Jan 4 2012, In : Unknown Journal.

Research output: Contribution to journalArticle

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling

Wei, S. C., Rosenberg, I. M., Cao, Z., Huett, A. S., Xavier, R. J. & Podolsky, D. K., May 1 2012, In : Inflammatory bowel diseases. 18, 5, p. 877-888 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: Meta-analysis of individual patient data

Mathurin, P., O'Grady, J., Carithers, R. L., Phillips, M., Louvet, A., Mendenhall, C. L., Ramond, M. J., Naveau, S., Maddrey, W. C. & Morgan, T. R., Feb 2011, In : Gut. 60, 2, p. 255-260 6 p.

Research output: Contribution to journalArticle

261 Scopus citations

Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis

Mueller, T., Beutler, C., Picó, A. H., Shibolet, O., Pratt, D. S., Pascher, A., Neuhaus, P., Wiedenmann, B., Berg, T. & Podolsky, D. K., Nov 1 2011, In : Liver International. 31, 10, p. 1574-1588 15 p.

Research output: Contribution to journalArticle

53 Scopus citations

Evaluation of drug-induced serious hepatotoxicity (eDISH): Application of this data organization approach to phase III clinical trials of rivaroxaban after total hip or knee replacement surgery

Watkins, P. B., Desai, M., Berkowitz, S. D., Peters, G., Horsmans, Y., Larrey, D. & Maddrey, W., 2011, In : Drug Safety. 34, 3, p. 243-252 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Preface

Schiff, E. R., Maddrey, W. C. & Sorrell, M. F., Oct 31 2011, In : Unknown Journal.

Research output: Contribution to journalArticle

3 Scopus citations

Schiff's Diseases of the Liver

Schiff, E. R., Maddrey, W. C. & Sorrell, M. F., Oct 31 2011, Wiley-Blackwell.

Research output: Book/ReportBook

15 Scopus citations

Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer

Eyking, A., Ey, B., Rünzi, M., Roig, A. I., Reis, H., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Dec 2011, In : Gastroenterology. 141, 6, p. 2154-2165 12 p.

Research output: Contribution to journalArticle

59 Scopus citations
2010

Activity 1: Overview of the viral hepatitis problem

Lok, A. S. F., Kim, W. R., El-Serag, H. B. & Maddrey, W. C., Apr 1 2010, In : Journal of Family Practice. 59, SUPPL. 4, p. S11-S16

Research output: Contribution to journalArticle

2 Scopus citations

Biological Basis of Healing and Repair in Remission and Relapse

Playford, R. J. & Podolsky, D. K., May 18 2010, Inflammatory Bowel Disease: Translating basic science into clinical practice. Wiley-Blackwell, p. 170-181 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3

Beck, P. L., Ihara, E., Hirota, S. A., MacDonald, J. A., Meng, D., Nanthakumar, N. N., Podolsky, D. K. & Xavier, R. J., Jul 1 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 1, p. G43-G53

Research output: Contribution to journalArticle

17 Scopus citations

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Surolia, I., Pirnie, S. P., Chellappa, V., Taylor, K. N., Cariappa, A., Moya, J., Liu, H., Bell, D. W., Driscoll, D. R., Diederichs, S., Haider, K., Netravali, I., Le, S., Elia, R., Dow, E., Lee, A., Freudenberg, J., De Jager, P. L., Chretien, Y., Varki, A. & 13 others, MacDonald, M. E., Gillis, T., Behrens, T. W., Bloch, D., Collier, D., Korzenik, J., Podolsky, D. K., Hafler, D., Murali, M., Sands, B., Stone, J. H., Gregersen, P. K. & Pillai, S., Jul 8 2010, In : Nature. 466, 7303, p. 243-247 5 p.

Research output: Contribution to journalArticle

122 Scopus citations

Identification of Drosophila yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters

Charrière, G. M., Ip, W. K. E., Dejardin, S., Boyer, L., Sokolovska, A., Cappillino, M. P., Cherayil, B. J., Podolsky, D. K., Kobayashi, K. S., Silverman, N., Lacy-Hulbert, A. & Stuart, L. M., Jun 25 2010, In : Journal of Biological Chemistry. 285, 26, p. 20147-20154 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

In vivo action of trefoil factor 2 (TFF2) to speed gastric repair is independent of cyclooxygenase

Xue, L., Aihara, E., Podolsky, D. K., Wang, T. C. & Montrose, M. H., Sep 2010, In : Gut. 59, 9, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

LRRK2 is involved in the IFN-γ response and host response to pathogens

Gardet, A., Benita, Y., Li, C., Sands, B. E., Ballester, I., Stevens, C., Korzenik, J. R., Rioux, J. D., Daly, M. J., Xavier, R. J. & Podolsky, D. K., Nov 1 2010, In : Journal of Immunology. 185, 9, p. 5577-5585 9 p.

Research output: Contribution to journalReview article

204 Scopus citations

MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function

Yamamoto-Furusho, J. K., Barnich, N., Hisamatsu, T. & Podolsky, D. K., Apr 16 2010, In : Inflammatory bowel diseases. 16, 5, p. 736-742 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Synthesis of biologically active biotinylated muramyl dipeptides

Grimes, C. L., Podolsky, D. K. & O'Shea, E. K., Oct 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6061-6063 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

The ribavirin pregnancy registry: Findings after 5 years of enrollment, 2003-2009

Roberts, S. S., Miller, R. K., Jones, J. K., Lindsay, K. L., Greene, M. F., Maddrey, W. C., Williams, I. T., Liu, J. & Spiegel, R. J., Jul 1 2010, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 88, 7, p. 551-559 9 p.

Research output: Contribution to journalArticle

42 Scopus citations
2009

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy

Huett, A., Ng, A., Cao, Z., Kuballa, P., Komatsu, M., Daly, M. J., Podolsky, D. K. & Xavier, R. J., Apr 15 2009, In : Journal of Immunology. 182, 8, p. 4917-4930 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Beyond tumor necrosis factor: Next-generation biologic therapy for inflammatory bowel disease

Podolsky, D. K., Oct 19 2009, In : Digestive Diseases. 27, 3, p. 366-369 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency

Podolsky, D. K., Gerken, G., Eyking, A. & Cario, E., Jul 2009, In : Gastroenterology. 137, 1, p. 209-220 12 p.

Research output: Contribution to journalArticle

147 Scopus citations

Development of the Gastrointestinal System

Stanger, B. Z. & Podolsky, D. K., Feb 17 2009, Textbook of Gastroenterology, Fifth Edition. Blackwell Publishing Ltd, Vol. 1. p. 567-602 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Editorial introductions

Podolsky, D. K., Cohen, M. & Bresalier, R., Jan 1 2009, In : Current Opinion in Gastroenterology. 25, 1

Research output: Contribution to journalEditorial

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

Huett, A., Leong, J. M., Podolsky, D. K. & Xavier, R. J., Jul 15 2009, In : Experimental Cell Research. 315, 12, p. 2001-2011 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury

Ey, B., Eyking, A., Gerken, G., Podolsky, D. K. & Cario, E., Aug 14 2009, In : Journal of Biological Chemistry. 284, 33, p. 22332-22343 12 p.

Research output: Contribution to journalArticle

77 Scopus citations