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2019

Changing Times in Liver Transplantation for Alcohol-Associated Liver Disease

Mitchell, M. C. & Maddrey, W. C., Jan 1 2019, (Accepted/In press) In : JAMA Internal Medicine.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data From Controlled Trials

Louvet, A., Thursz, M. R., Kim, D. J., Labreuche, J., Atkinson, S. R., Sidhu, S. S., O'Grady, J. G., Akriviadis, E., Sinakos, E., Carithers, R. L., Ramond, M. J., Maddrey, W. C., Morgan, T. R., Duhamel, A. & Mathurin, P., Aug 2018, In : Gastroenterology. 155, 2, p. 458-468.e8

Research output: Contribution to journalArticle

31 Scopus citations

Food for thought: Importance of nutrition in alcoholic hepatitis

Aday, A. W. & Mitchell, M. C., Mar 2018, In : Practical Gastroenterology. 42, 3, p. 30-36 7 p.

Research output: Contribution to journalArticle

2017

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCϵ-dependent Pathway

Wei, S. C., Yang-Yen, H. F., Tsao, P. N., Weng, M. T., Tung, C. C., Yu, L. C. H., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Ni, Y. H., Xavier, R. J., Podolsky, D. K., Yen, J. J. Y. & Wong, J. M., Oct 1 2017, In : Inflammatory Bowel Diseases. 23, 10, p. 1730-1740 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Ribavirin Pregnancy Registry: An Interim Analysis of Potential Teratogenicity at the Mid-Point of Enrollment

Sinclair, S. M., Jones, J. K., Miller, R. K., Greene, M. F., Kwo, P. Y. & Maddrey, W. C., Jul 8 2017, (Accepted/In press) In : Drug Safety. p. 1-14 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Gastroenterology, Academic Medicine and a Changing Landscape

Podolsky, D. K., Sep 23 2015, In : Digestive Diseases. 33, p. 57-60 4 p.

Research output: Contribution to journalArticle

Reflections on mentorship on the occasion of Dr Kurt J. Isselbacher's 90th birthday

Podolsky, D. K., Aug 1 2015, In : Gastroenterology. 149, 2, p. 268-269 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Texas medical center keeps its focus on process improvement

Podolsky, D. & Kutscher, B., Jul 27 2015, In : Modern Healthcare. 45, 30, p. 30-31 2 p.

Research output: Contribution to journalArticle

2014

Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertension

Dingemanse, J., Sidharta, P. N., Maddrey, W. C., Rubin, L. J. & Mickail, H., Mar 1 2014, In : Expert Opinion on Drug Safety. 13, 3, p. 391-405 15 p.

Research output: Contribution to journalArticle

43 Scopus citations

Public reporting of patient safety metrics: Ready or not?

Podolsky, D. K., Nagarkar, P. A., Reed, W. G. & Rohrich, R. J., Jan 1 2014, In : Plastic and reconstructive surgery. 134, 6, p. 981e-985e

Research output: Contribution to journalArticle

2 Scopus citations

SLCO3A1, a novel Crohn's disease-associated gene, regulates NF-κB activity and associates with intestinal perforation

Wei, S. C., Tan, Y. Y., Weng, M. T., Lai, L. C., Hsiao, J. H., Chuang, E. Y., Shun, C. T., Wu, D. C., Kao, A. W., Chuang, C. S., Ni, Y. H., Shieh, M. J., Tung, C. C., Chen, Y., Wang, C. Y., Xavier, R. J., Podolsky, D. K. & Wong, J. M., Jun 19 2014, In : PloS one. 9, 6, e100515.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships.

Fordtran, J. S., Goyal, R. K., Feldman, M., Soll, A. H., Trier, J. S., Ockner, R. K., Larusso, N. F., Podolsky, D. K., Brenner, D. A., Rustgi, A. K. & Omary, M. B., Jul 2013, In : Gastroenterology. 145, 1, p. 16-31 16 p.

Research output: Contribution to journalArticle

2 Scopus citations

Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier

Müller, T., Beutler, C., Picó, A. H., Otten, M., Dürr, A., Al-Abadi, H., Guckelberger, O., Meyer Zum Büschenfelde, D., Jöhrens, K., Volkmann, M., Lankisch, T., Voigtländer, T., Anders, M., Shibolet, O., Jefferson, D. M., Podolsky, D. K., Fischer, A., Veltzke-Schlieker, W., Adler, A., Baumgart, D. C. & 4 others, Sturm, A., Wiedenmann, B., Schott, E. & Berg, T., May 2013, In : Gastroenterology. 144, 5, p. 1116-1128 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Kenji Fujiwara, MD, PhD.

Sugano, K., Podolsky, D. K., Brenner, D. A., Michalopoulos, G. & Tsukamoto, H., Apr 2013, In : Unknown Journal. 144, 4, p. 661-663 3 p.

Research output: Contribution to journalArticle

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis

Ey, B., Eyking, A., Klepak, M., Salzman, N. H., Göthert, J. R., Run̈zi, M., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5676-5688 13 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Foreword

Podolsky, D. K., Jan 1 2012, In : Unknown Journal. p. v-vi

Research output: Contribution to journalArticle

Forward

Podolsky, D. K., Jan 4 2012, In : Unknown Journal.

Research output: Contribution to journalArticle

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling

Wei, S. C., Rosenberg, I. M., Cao, Z., Huett, A. S., Xavier, R. J. & Podolsky, D. K., May 1 2012, In : Inflammatory bowel diseases. 18, 5, p. 877-888 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: Meta-analysis of individual patient data

Mathurin, P., O'Grady, J., Carithers, R. L., Phillips, M., Louvet, A., Mendenhall, C. L., Ramond, M. J., Naveau, S., Maddrey, W. C. & Morgan, T. R., Feb 1 2011, In : Gut. 60, 2, p. 255-260 6 p.

Research output: Contribution to journalArticle

257 Scopus citations

Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis

Mueller, T., Beutler, C., Picó, A. H., Shibolet, O., Pratt, D. S., Pascher, A., Neuhaus, P., Wiedenmann, B., Berg, T. & Podolsky, D. K., Nov 1 2011, In : Liver International. 31, 10, p. 1574-1588 15 p.

Research output: Contribution to journalArticle

53 Scopus citations

Evaluation of drug-induced serious hepatotoxicity (eDISH): Application of this data organization approach to phase III clinical trials of rivaroxaban after total hip or knee replacement surgery

Watkins, P. B., Desai, M., Berkowitz, S. D., Peters, G., Horsmans, Y., Larrey, D. & Maddrey, W., Feb 24 2011, In : Drug Safety. 34, 3, p. 243-252 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Preface

Schiff, E. R., Maddrey, W. C. & Sorrell, M. F., Oct 31 2011, In : Unknown Journal.

Research output: Contribution to journalArticle

3 Scopus citations

Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer

Eyking, A., Ey, B., Rünzi, M., Roig, A. I., Reis, H., Schmid, K. W., Gerken, G., Podolsky, D. K. & Cario, E., Dec 2011, In : Gastroenterology. 141, 6, p. 2154-2165 12 p.

Research output: Contribution to journalArticle

59 Scopus citations
2010

Activity 1: Overview of the viral hepatitis problem

Lok, A. S. F., Kim, W. R., El-Serag, H. B. & Maddrey, W. C., Apr 1 2010, In : Journal of Family Practice. 59, SUPPL. 4, p. S11-S16

Research output: Contribution to journalArticle

2 Scopus citations

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3

Beck, P. L., Ihara, E., Hirota, S. A., MacDonald, J. A., Meng, D., Nanthakumar, N. N., Podolsky, D. K. & Xavier, R. J., Jul 1 2010, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 299, 1, p. G43-G53

Research output: Contribution to journalArticle

17 Scopus citations

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Surolia, I., Pirnie, S. P., Chellappa, V., Taylor, K. N., Cariappa, A., Moya, J., Liu, H., Bell, D. W., Driscoll, D. R., Diederichs, S., Haider, K., Netravali, I., Le, S., Elia, R., Dow, E., Lee, A., Freudenberg, J., De Jager, P. L., Chretien, Y., Varki, A. & 13 others, MacDonald, M. E., Gillis, T., Behrens, T. W., Bloch, D., Collier, D., Korzenik, J., Podolsky, D. K., Hafler, D., Murali, M., Sands, B., Stone, J. H., Gregersen, P. K. & Pillai, S., Jul 8 2010, In : Nature. 466, 7303, p. 243-247 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Identification of Drosophila yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters

Charrière, G. M., Ip, W. K. E., Dejardin, S., Boyer, L., Sokolovska, A., Cappillino, M. P., Cherayil, B. J., Podolsky, D. K., Kobayashi, K. S., Silverman, N., Lacy-Hulbert, A. & Stuart, L. M., Jun 25 2010, In : Journal of Biological Chemistry. 285, 26, p. 20147-20154 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

In vivo action of trefoil factor 2 (TFF2) to speed gastric repair is independent of cyclooxygenase

Xue, L., Aihara, E., Podolsky, D. K., Wang, T. C. & Montrose, M. H., Sep 2010, In : Gut. 59, 9, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function

Yamamoto-Furusho, J. K., Barnich, N., Hisamatsu, T. & Podolsky, D. K., Apr 16 2010, In : Inflammatory bowel diseases. 16, 5, p. 736-742 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Synthesis of biologically active biotinylated muramyl dipeptides

Grimes, C. L., Podolsky, D. K. & O'Shea, E. K., Oct 1 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 20, p. 6061-6063 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

The ribavirin pregnancy registry: Findings after 5 years of enrollment, 2003-2009

Roberts, S. S., Miller, R. K., Jones, J. K., Lindsay, K. L., Greene, M. F., Maddrey, W. C., Williams, I. T., Liu, J. & Spiegel, R. J., Jul 1 2010, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 88, 7, p. 551-559 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
2009

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy

Huett, A., Ng, A., Cao, Z., Kuballa, P., Komatsu, M., Daly, M. J., Podolsky, D. K. & Xavier, R. J., Apr 15 2009, In : Journal of Immunology. 182, 8, p. 4917-4930 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Beyond tumor necrosis factor: Next-generation biologic therapy for inflammatory bowel disease

Podolsky, D. K., Oct 19 2009, In : Digestive Diseases. 27, 3, p. 366-369 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency

Podolsky, D. K., Gerken, G., Eyking, A. & Cario, E., Jul 2009, In : Gastroenterology. 137, 1, p. 209-220 12 p.

Research output: Contribution to journalArticle

143 Scopus citations

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements

Huett, A., Leong, J. M., Podolsky, D. K. & Xavier, R. J., Jul 15 2009, In : Experimental Cell Research. 315, 12, p. 2001-2011 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury

Ey, B., Eyking, A., Gerken, G., Podolsky, D. K. & Cario, E., Aug 14 2009, In : Journal of Biological Chemistry. 284, 33, p. 22332-22343 12 p.

Research output: Contribution to journalArticle

77 Scopus citations
2008

Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds

Paulsen, F. P., Woon, C. W., Varoga, D., Jansen, A., Garreis, F., Jäger, K., Amm, M., Podolsky, D. K., Steven, P., Barker, N. P. & Sel, S., May 9 2008, In : Journal of Biological Chemistry. 283, 19, p. 13418-13427 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

TNF Receptor Type I-Dependent Activation of Innate Responses to Reduce Intestinal Damage-Associated Mortality

Mizoguchi, E., Hachiya, Y., Kawada, M., Nagatani, K., Ogawa, A., Sugimoto, K., Mizoguchi, A. & Podolsky, D. K., Feb 2008, In : Gastroenterology. 134, 2, p. 470-480 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling

Shibolet, O., Giallourakis, C., Rosenberg, I., Mueller, T., Xavier, R. J. & Podolsky, D. K., Nov 30 2007, In : Journal of Biological Chemistry. 282, 48, p. 35308-35317 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Hepatitis B virus infection in 6,130 unvaccinated Korean-Americans surveyed between 1988 and 1990

Hann, H. W. L., Hann, R. S. & Maddrey, W. C., Apr 1 2007, In : American Journal of Gastroenterology. 102, 4, p. 767-772 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Innate immunity in inflammatory bowel disease

Yamamoto-Furusho, J. K. & Podolsky, D. K., Nov 14 2007, In : World Journal of Gastroenterology. 13, 42, p. 5577-5580 4 p.

Research output: Contribution to journalArticle

66 Scopus citations

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

De Jager, P. L., Franchimont, D., Waliszewska, A., Bitton, A., Cohen, A., Langelier, D., Belaiche, J., Vermeire, S., Farwell, L., Goris, A., Libioulle, C., Jani, N., Dassopoulos, T., Bromfield, G. P., Dubois, B., Cho, J. H., Brant, S. R., Duerr, R. H., Yang, H., Rotter, J. I. & 7 others, Silverberg, M. S., Steinhart, A. H., Daly, M. J., Podolsky, D. K., Louis, E., Hafler, D. A. & Rioux, J. D., Jul 1 2007, In : Genes and Immunity. 8, 5, p. 387-397 11 p.

Research output: Contribution to journalArticle

114 Scopus citations
168 Scopus citations

Toll-Like Receptor 2 Controls Mucosal Inflammation by Regulating Epithelial Barrier Function

Cario, E., Gerken, G. & Podolsky, D. K., Apr 2007, In : Gastroenterology. 132, 4, p. 1359-1374 16 p.

Research output: Contribution to journalArticle

441 Scopus citations
2006

Case 8-2006: A 71-year-old woman with Crohn's disease and altered mental status

Podolsky, D. K., Gonzalez, R. G., Hasserjian, R. P., Harris, N. L. & Hochberg, E. P., Mar 16 2006, In : New England Journal of Medicine. 354, 11, p. 1178-1184 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Centaurin β1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-κB activation

Yamamoto-Furusho, J. K., Barnich, N., Xavier, R., Hisamatsu, T. & Podolsky, D. K., Nov 24 2006, In : Journal of Biological Chemistry. 281, 47, p. 36060-36070 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Foreword

Maddrey, W. C., 2006, In : Unknown Journal.

Research output: Contribution to journalArticle

Th2 cytokines down-regulate TLR expression and function in human intestinal epithelial cells

Mueller, T., Terada, T., Rosenberg, I. M., Shibolet, O. & Podolsky, D. K., May 15 2006, In : Journal of Immunology. 176, 10, p. 5805-5814 10 p.

Research output: Contribution to journalArticle

Open Access
83 Scopus citations

Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance

Cario, E., Golenbock, D. T., Visintin, A., Rünzi, M., Gerken, G. & Podolsky, D. K., Apr 1 2006, In : Journal of Immunology. 176, 7, p. 4258-4266 9 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations
38 Scopus citations