PA-Lab Chen Mingyi

Research output

Research output per year 2019 2019 2020 2021 2022 2023 2024

• 36 Article
• 8 Review article
• 4 Letter
• 3 Chapter
• 1 More
  • 1 Editorial

Research output per year

Research output per year

Search results

• 2024

  Clinicopathologic features of relapsed CD19(−) B-ALL in CD19-targeted immunotherapy: Biological insights into relapse and LILRB1 as a novel B-cell marker for CD19(−) B lymphoblasts

  Chen, D., Fuda, F., Rosado, F., Saumell, S., John, S., Chen, M., Koduru, P. & Chen, W., 2024, (Accepted/In press) In: International Journal of Laboratory Hematology.

  Research output: Contribution to journal › Article › peer-review

  • Leukocyte Immunoglobulin-like Receptor B1 100%
  • Cytogenetics 74%
  • blinatumomab 61%
  • Immunotherapy 46%
  • Marker 46%

• Severely polarized extracellular acidity around tumour cells

  Feng, Q., Bennett, Z., Grichuk, A., Pantoja, R., Huang, T., Faubert, B., Huang, G., Chen, M., DeBerardinis, R. J., Sumer, B. D. & Gao, J., 2024, (Accepted/In press) In: Nature Biomedical Engineering.

  Research output: Contribution to journal › Article › peer-review

  • Acidity 100%
  • Tumors 74%
  • Cells 70%
  • Nanoprobes 65%
  • Chemical activation 32%
• 2023

  Advances in molecular evaluation of myeloproliferative neoplasms

  Li, N., Chen, M. & Yin, C. C., May 2023, In: Seminars in Diagnostic Pathology. 40, 3, p. 187-194 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Protein-Tyrosine Kinases 100%
  • Neoplasms 82%
  • Blast Crisis 49%
  • Gene Rearrangement 42%
  • Mutation 41%
  1 Scopus citations

• Artificial intelligence in clinical multiparameter flow cytometry and mass cytometry–key tools and progress

  Fuda, F., Chen, M., Chen, W. & Cox, A., Mar 2023, In: Seminars in Diagnostic Pathology. 40, 2, p. 120-128 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Artificial Intelligence 100%
  • Flow Cytometry 57%
  • Machine Learning 28%
  • Workflow 27%
  • Supervised Machine Learning 20%
  5 Scopus citations

• CD138^- Plasmablastic Lymphoma A Multi-institutional Study and Review of the Literature

  Choudhuri, J., Pan, Z., Yuan, J., Chen, M., Wu, X., Zheng, G., Zhao, C., Yuan, Y., Agarwal, B., Liu, J., Ma, M. Y., Wang, Y. & Shi, Y., Jun 2023, In: Archives of Pathology and Laboratory Medicine. 147, 6, p. 643-654 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plasmablastic Lymphoma 100%
  • Human Herpesvirus 4 60%
  • Immunoglobulin Light Chains 55%
  • Epstein-Barr Virus Infections 48%
  • Plasma Cells 20%
  2 Scopus citations

• Deep learning in digital pathology for personalized treatment plans of cancer patients

  Wen, Z., Wang, S., Yang, D. M., Xie, Y., Chen, M., Bishop, J. & Xiao, G., Mar 2023, In: Seminars in Diagnostic Pathology. 40, 2, p. 109-119 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Deep Learning 100%
  • Pathology 46%
  • Artificial Intelligence 27%
  • Biomarkers 27%
  • Neoplasms 23%
  6 Scopus citations

• Digital pathology and artificial intelligence as the next chapter in diagnostic hematopathology

  Lin, E., Fuda, F., Luu, H. S., Cox, A. M., Fang, F., Feng, J. & Chen, M., Mar 2023, In: Seminars in Diagnostic Pathology. 40, 2, p. 88-94 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Artificial Intelligence 100%
  • Pathology 47%
  • Workflow 41%
  • Pathologists 36%
  • Hematologic Diseases 21%
  11 Scopus citations

• Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance

  Lyu, J., Liu, Y., Gong, L., Chen, M., Madanat, Y. F., Zhang, Y., Cai, F., Gu, Z., Cao, H., Kaphle, P., Kim, Y. J., Kalkan, F. N., Stephens, H., Dickerson, K. E., Ni, M., Chen, W., Patel, P., Mims, A. S., Borate, U., Burd, A., & 8 othersCai, S. F., Yin, C. C., You, M. J., Chung, S. S., Collins, R. H., DeBerardinis, R. J., Liu, X. & Xu, J., Jan 9 2023, In: Cancer discovery. 13, 1, p. 170-193 24 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutation 100%
  • Acute Myeloid Leukemia 73%
  • NADP 55%
  • Leukemia 41%
  • Amino Acids 35%
  5 Scopus citations

• Distinct mutational and clinicopathologic profiles characterize acute myeloid leukemia with cup-like nuclei

  Oertling, E., Fuda, F., Koduru, P., Chen, M., Weinberg, O., Juntilla, M., Jaso, J., Vusirikala, M., Chung, S., Geethakumari, P. R., Madanat, Y. F., Collins, R., Gagan, J. & Chen, W., Jan 2023, In: Leukemia Research. 124, 106995.

  Research output: Contribution to journal › Letter › peer-review

• Hematolymphoid Tumors of the Sinonasal Tract

  Rosado, F. G. & Chen, M., Jan 1 2023, Atlas of Sinonasal Tract Pathology. Springer Nature, p. 203-222 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Paranasal Sinuses 100%
  • Plasmablastic Lymphoma 36%
  • Extranodal NK-T-Cell Lymphoma 35%
  • Neoplasms 28%
  • Plasmacytoma 27%

• Isoform-specific disruption of the TP73 gene reveals a critical role for TAp73γ in tumorigenesis via leptin

  Kong, X., Yan, W., Sun, W., Zhang, Y., Yang, H. J., Chen, M., Chen, H., de Vere White, R. W., Zhang, J. & Chen, X., 2023, In: eLife. 12, e82115.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Leptin 100%
  • Oncogenic 54%
  • Exons 48%
  • Protein Isoforms 47%
  • Pharmacological Metabolism 45%

• Poly zinc finger protein ZFP14 suppresses lymphomagenesis and abnormal inflammatory response via the HOXA gene cluster

  Mohibi, S., Chen, M., Chen, X. & Zhang, J., Jan 1 2023, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1869, 1, 166587.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zinc Fingers 100%
  • Multigene Family 95%
  • Proteins 32%
  • Neoplasms 28%
  • Interleukin-18 25%
  1 Scopus citations

• Preface: Artificial intelligence (AI), machine learning ML) and digital pathology integration are the next major chapter in our diagnostic pathology and laboratory medicine arena

  Rashidi, H. H. & Chen, M., Mar 2023, In: Seminars in Diagnostic Pathology. 40, 2, p. 69-70 2 p.

  Research output: Contribution to journal › Review article › peer-review

  • Artificial Intelligence 100%
  • Machine Learning 85%
  • Medicine 55%
  • Pathology 47%
  3 Scopus citations

• TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response

  Zhang, J., Sun, W., Yan, W., Kong, X., Shen, T., Laubach, K., Chen, M. & Chen, X., Jan 2023, In: Cell Death and Disease. 14, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein Isoforms 100%
  • Ferroptosis 97%
  • Cysteine Dioxygenase 74%
  • Fatty Liver 66%
  • Growth 62%
  1 Scopus citations
• 2022

  A Combined Biomarker of Bright CD38 and MYC ≥55% Is Highly Predictive of Double-/Triple-Hit High-Grade B-Cell Lymphoma

  Alsuwaidan, A., Koduru, P., Fuda, F., Manuel Jaso, J., Chen, M., Rosado, F., Luu, H. S., Sweed, N., Garcia, R., Doucet, M., Desai, N. B., Kumar, K. A., Awan, F. T., Ramakrishnan Geethakumari, P. & Chen, W., Sep 1 2022, In: American journal of clinical pathology. 158, 3, p. 338-344 7 p.

  Research output: Contribution to journal › Article › peer-review

  • B-Cell Lymphoma 100%
  • Non-Hodgkin's Lymphoma 91%
  • Lymphoma 80%
  • Biomarkers 62%
  • Flow Cytometry 46%
  4 Scopus citations

• Epstein-Barr Virus-Positive Plasma Cell Neoplasm of Nasal Cavity in an Immunocompetent Adult

  He, L., Ryan, M. W. & Chen, M., Oct 2022, In: JAMA Otolaryngology - Head and Neck Surgery. 148, 10, p. 989-991 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway

  Zhang, Y., Mohibi, S., Vasilatis, D. M., Chen, M., Zhang, J. & Chen, X., Mar 18 2022, In: Oncogene. 41, 12, p. 1718-1726 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ferredoxins 100%
  • Oxidoreductases 59%
  • Homeostasis 48%
  • Lipids 42%
  • Cholesterol 36%
  11 Scopus citations

• Flow cytometry in the diagnosis of autoimmune-related lymphoproliferative disorder and lymphoma in the head and neck region

  (Jonathan) He, L., Fuda, F. & Chen, M., Jan 1 2022, Translational Autoimmunity: Challenges for Autoimmune Diseases: Volume 5. Elsevier, Vol. 5. p. 17-36 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Lymphoproliferative Disorders 100%
  • Salivary Glands 88%
  • Lymphoma 70%
  • Lacrimal Apparatus 68%
  • Flow Cytometry 64%

• Hematologic Complications in Patients Hospitalized with COVID-19 Infection

  Lin, E., Araj, E., Markantonis, J., Luu, H. & Chen, M., Sep 2022, In: Hematology Reports. 14, 3, p. 228-234 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Infections 100%
  • Intensive Care Units 86%
  • Dacarbazine 66%
  • Lymphopenia 63%
  • Hemolysis 54%
  1 Scopus citations

• Human herpesvirus 8-negative effusion-based large B-cell lymphoma: a distinct entity with unique clinicopathologic characteristics

  Gisriel, S. D., Yuan, J., Braunberger, R. C., Maracaja, D. L. V., Chen, X., Wu, X., McCracken, J., Chen, M., Xie, Y., Brown, L. E., Li, P., Zhou, Y., Sethi, T., McHenry, A., Hauser, R. G., Paulson, N., Tang, H., Hsi, E. D., Wang, E., Zhang, Q. Y., & 3 othersYoung, K. H., Xu, M. L. & Pan, Z., Oct 2022, In: Modern Pathology. 35, 10, p. 1411-1422 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Human Herpesvirus 8 100%
  • B-Cell Lymphoma 80%
  • Herpesviridae Infections 28%
  • Primary Effusion Lymphoma 16%
  • Pleural Cavity 14%
  11 Scopus citations

• Mast cell sarcoma: clinicopathologic and molecular analysis of 10 new cases and review of literature

  Matsumoto, N. P., Yuan, J., Wang, J., Shen, Q., Chen, X., Kim, Y., Zuppan, C. W., Chang, C. C., Cui, W., Chen, D., Shi, M., Gisriel, S. D., Chen, M., Xu, M. L. & Pan, Z., Jul 2022, In: Modern Pathology. 35, 7, p. 865-874 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mast-Cell Sarcoma 100%
  • Tryptases 19%
  • Germ Cell and Embryonal Neoplasms 17%
  • Mast Cells 14%
  • Dysgerminoma 11%
  6 Scopus citations

• Metabolon formation regulates branched-chain amino acid oxidation and homeostasis

  Patrick, M. K., Gu, Z., Zhang, G., Wynn, R. M., Kaphle, P., Cao, H., Vu, H., Cai, F., Gao, X., Zhang, Y., Chen, M., Ni, M., Chuang, D. T., DeBerardinis, R. J. & Xu, J., Dec 2022, In: Nature Metabolism. 4, 12, p. 1775-1791 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Branched Chain Amino Acids 100%
  • Homeostasis 56%
  • Keto Acids 32%
  • Isoenzymes 21%
  • branched-chain-amino-acid transaminase 18%
  6 Scopus citations

• p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1

  Laubach, K. N., Yan, W., Kong, X., Sun, W., Chen, M., Zhang, J. & Chen, X., May 31 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 22, e2123202119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exons 100%
  • Protein Isoforms 96%
  • Neoplasms 38%
  • Clustered Regularly Interspaced Short Palindromic Repeats 27%
  • Ectopic Gene Expression 26%
  2 Scopus citations

• Preface of the Special Issue “COVID-19 Infection and Hematological Malignancies”

  Chen, M. & Anderson, L. D., Sep 2022, In: Cancers. 14, 18, 4497.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  1 Scopus citations

• SARS-CoV-2 infection associated with aplastic anemia and pure red cell aplasia

  Lee, N. C. J., Patel, B., Etra, A., Bat, T., Ibrahim, I. F., Vusirikala, M., Chen, M., Rosado, F., Jaso, J. M., Young, N. S. & Chen, W., Jul 12 2022, In: Blood Advances. 6, 13, p. 3840-3843 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  6 Scopus citations

• Sprod for de-noising spatially resolved transcriptomics data based on position and image information

  Wang, Y., Song, B., Wang, S., Chen, M., Xie, Y., Xiao, G., Wang, L. & Wang, T., Aug 2022, In: Nature methods. 19, 8, p. 950-958 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Sequencing 100%
  • Noise 55%
  • Biomedical Technology 38%
  • Pathology 38%
  • Gene Expression 36%
  12 Scopus citations
• 2021

  A Machine Learning Tool Using Digital Microscopy (Morphogo) for the Identification of Abnormal Lymphocytes in the Bone Marrow

  Tang, G., Fu, X., Wang, Z. & Chen, M., Aug 1 2021, In: Acta Cytologica. 65, 4, p. 354-357 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Machine Learning 100%
  • Microscopy 73%
  • Bone Marrow 64%
  • Lymphocytes 61%
  • B-Cell Chronic Lymphocytic Leukemia 20%
  7 Scopus citations

• DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

  Lu, C., Guan, J., Lu, S., Jin, Q., Rousseau, B., Lu, T., Stephens, D., Zhang, H., Zhu, J., Yang, M., Ren, Z., Liang, Y., Liu, Z., Han, C., Liu, L., Cao, X., Zhang, A., Qiao, J., Batten, K., Chen, M., & 6 othersCastrillon, D. H., Wang, T., Li, B., Diaz, L. A., Li, G. M. & Fu, Y. X., Jan 11 2021, In: Cancer Cell. 39, 1, p. 96-108.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA Mismatch Repair 100%
  • Immunity 68%
  • DNA 46%
  • Turcot syndrome 45%
  • DNA Repair-Deficiency Disorders 44%
  140 Scopus citations

• Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38

  Sun, W., Laubach, K., Lucchessi, C., Zhang, Y., Chen, M., Zhang, J. & Chen, X., Apr 1 2021, In: Genes and Development. 35, 78, p. 542-555 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eukaryotic Initiation Factors 100%
  • RNA-Binding Proteins 85%
  • Serine 71%
  • Cellular Senescence 27%
  • Protein Biosynthesis 26%
  5 Scopus citations

• Mice deficient in the RNA-binding protein zfp871 are prone to early death and steatohepatitis in part through the p53–Mdm2 axis

  Mohibi, S., Zhang, J., Chen, M. & Chen, X., Oct 2021, In: Molecular Cancer Research. 19, 10, p. 1751-1762 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA-Binding Proteins 100%
  • Fatty Liver 92%
  • RNA-Seq 25%
  • Ubiquitin-Protein Ligases 24%
  • Zinc Fingers 24%
  4 Scopus citations

• MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

  Guan, J., Lu, C., Jin, Q., Lu, H., Chen, X., Tian, L., Zhang, Y., Ortega, J., Zhang, J., Siteni, S., Chen, M., Gu, L., Shay, J. W., Davis, A. J., Chen, Z. J., Fu, Y. X. & Li, G. M., Jan 11 2021, In: Cancer Cell. 39, 1, p. 109-121.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • exodeoxyribonuclease I 100%
  • Exodeoxyribonucleases 97%
  • DNA Mismatch Repair 68%
  • DNA Repair 21%
  • DNA Breaks 14%
  98 Scopus citations

• Myeloid/lymphoid neoplasm with FGFR1 rearrangement

  Germans, S. K. & Chen, M., Sep 9 2021, In: Blood. 138, 10, p. 912 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma

  Hannan, R., Mohamad, O., de Leon, A. D., Manna, S., Pop, L. M., Zhang, Z., Mannala, S., Christie, A., Christley, S., Monson, N., Ishihara, D., Hsu, E. J., Ahn, C., Kapur, P., Chen, M., Arriaga, Y., Courtney, K., Cantarel, B., Wakeland, E. K., Fu, Y. X., & 7 othersPedrosa, I., Cowell, L., Wang, T., Margulis, V., Choy, H., Timmerman, R. D. & Brugarolas, J., Dec 15 2021, In: Clinical Cancer Research. 27, 24, p. 6716-6725 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Renal Cell Carcinoma 100%
  • Interleukin-2 92%
  • Radiotherapy 71%
  • Whole Exome Sequencing 41%
  • Neoplasm Metastasis 32%
  12 Scopus citations

• Small proline-rich protein 2a and 2d are regulated by the rbm38-p73 axis and associated with p73-dependent suppression of chronic inflammation

  Kong, X., Wang, D., Sun, W., Chen, M., Chen, J., Shi, J., Zhang, J. & Chen, X., Jun 1 2021, In: Cancers. 13, 11, 2829.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cornified Envelope Proline-Rich Proteins 100%
  • Inflammation 31%
  • Longevity 19%
  • RNA-Binding Proteins 12%
  • Ectopic Gene Expression 11%
  1 Scopus citations
• 2020

  Application of flow cytometry in the analysis of lymphoid disease in the lung and pleural space

  Fu, M., Mani, M., Bradford, J., Chen, W., Chen, M. & Fuda, F., Nov 2020, In: Seminars in Diagnostic Pathology. 37, 6, p. 303-320 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pleural Diseases 100%
  • Lung Diseases 61%
  • Flow Cytometry 52%
  • Lung Neoplasms 40%
  • Pleural Cavity 22%
  2 Scopus citations

• FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression

  Zhang, J., Kong, X., Zhang, Y., Sun, W., Wang, J., Chen, M. & Chen, X., Jul 1 2020, In: Journal of Pathology. 251, 3, p. 284-296 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Iron-Binding Proteins 100%
  • Ferredoxins 98%
  • Oxidoreductases 58%
  • Neoplasms 20%
  • Fibroblasts 17%
  25 Scopus citations

• Morphogo: An Automatic Bone Marrow Cell Classification System on Digital Images Analyzed by Artificial Intelligence

  Fu, X., Fu, M., Li, Q., Peng, X., Lu, J., Fang, F. & Chen, M., Nov 1 2020, In: Acta Cytologica. 64, 6, p. 588-596 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Artificial Intelligence 100%
  • Bone Marrow Cells 71%
  • Bone Marrow 34%
  • Cell Count 21%
  • Pathologists 18%
  21 Scopus citations

• Noncoding variants connect enhancer dysregulation with nuclear receptor signaling in hematopoietic malignancies

  Li, K., Zhang, Y., Liu, X., Liu, Y., Gu, Z., Cao, H., Dickerson, K. E., Chen, M., Chen, W., Shao, Z., Ni, M. & Xu, J., May 2020, In: Cancer discovery. 10, 5, p. 724-745 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytoplasmic and Nuclear Receptors 100%
  • Hematologic Neoplasms 99%
  • Leukemia 63%
  • Neoplasms 25%
  • Clustered Regularly Interspaced Short Palindromic Repeats 22%
  22 Scopus citations

• Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

  Khuat, L. T., Le, C. T., Pai, C. C. S., Shields-Cutler, R. R., Holtan, S. G., Rashidi, A., Parker, S. L., Knights, D., Luna, J. I., Dunai, C., Wang, Z., Sturgill, I. R., Stoffel, K. M., Merleev, A. A., More, S. K., Maverakis, E., Raybould, H. E., Chen, M., Canter, R. J., Monjazeb, A. M., & 7 othersDave, M., Ferrara, J. L. M., Levine, J. E., Longo, D. L., Abedi, M., Blazar, B. R. & Murphy, W. J., Nov 2020, In: Science translational medicine. 12, 571, eaay7713.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Allogeneic Cells 100%
  • Graft vs Host Disease 97%
  • Stem Cell Transplantation 97%
  • Gastrointestinal Microbiome 91%
  • Hematopoietic Stem Cell Transplantation 88%
  30 Scopus citations

• PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

  Peng, Q., Qiu, X., Zhang, Z., Zhang, S., Zhang, Y., Liang, Y., Guo, J., Peng, H., Chen, M., Fu, Y. X. & Tang, H., Dec 1 2020, In: Nature communications. 11, 1, 4835.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dendritic Cells 100%
  • activation 88%
  • tumors 76%
  • T-Lymphocytes 69%
  • antigens 60%
  264 Scopus citations

• Special issue on diagnosis of primary hematolymphoid disease of the lung and pleura

  Chen, M., Nov 2020, In: Seminars in Diagnostic Pathology. 37, 6, p. 257-258 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Pleura 100%
  • Lung Diseases 76%
  • Lung 45%
  • Pathologists 41%
  • Neoplasms 13%

• Tumor neoantigenicity assessment with CSiN score incorporates clonality and immunogenicity to predict immunotherapy outcomes

  Lu, T., Wang, S., Xu, L., Zhou, Q., Singla, N., Gao, J., Manna, S., Pop, L., Xie, Z., Chen, M., Luke, J. J., Brugarolas, J., Hannan, R. & Wang, T., Feb 2020, In: Science Immunology. 5, 44, eaaz3199.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunotherapy 100%
  • Kidney Neoplasms 42%
  • Neoplasms 36%
  • Tumor Burden 18%
  • Melanoma 15%
  34 Scopus citations
• 2019

  CD123: A novel biomarker for diagnosis and treatment of leukemia

  Shi, M., Su, R. J., Parmar, K. P., Chaudhry, R., Sun, K., Rao, J. & Chen, M., 2019, In: Cardiovascular and Hematological Disorders - Drug Targets. 19, 3, p. 195-204 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Leukemia 100%
  • Biomarkers 79%
  • Stem Cells 71%
  • Interleukin-3 Receptor alpha Subunit 45%
  • Interleukin-3 Receptors 39%
  12 Scopus citations

• Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

  Pai, C. C. S., Huang, J. T., Lu, X., Simons, D. M., Park, C., Chang, A., Tamaki, W., Liu, E., Roybal, K. T., Seagal, J., Chen, M., Hagihara, K., Wei, X. X., DuPage, M., Kwek, S. S., Oh, D. Y., Daud, A., Tsai, K. K., Wu, C., Zhang, L., & 7 othersFasso, M., Sachidanandam, R., Jayaprakash, A., Lin, I., Casbon, A. J., Kinsbury, G. A. & Fong, L., Feb 19 2019, In: Immunity. 50, 2, p. 477-492.e8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clonal Deletion 100%
  • Tumor Burden 63%
  • Interferons 61%
  • T-Lymphocytes 41%
  • Immunotherapy 29%
  82 Scopus citations

• Disruption of the RBM38-eIF4E complex with a synthetic peptide PEP8 increases p53 expression

  Lucchesi, C. A., Zhang, J., Ma, B., Chen, M. & Chen, X., Feb 15 2019, In: Cancer research. 79, 4, p. 807-818 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eukaryotic Initiation Factor-4E 100%
  • Eukaryotic Initiation Factors 91%
  • Peptides 43%
  • Neoplasms 18%
  • Viperidae 15%
  27 Scopus citations

• Enumeration of Plasmacytoid Dendritic Cells in Peripheral Blood and Bone Marrow by Flow-Cytometric Analysis

  Alsuwaidan, A., Fuda, F., Chen, W. & Chen, M., 2019, Methods in Molecular Biology. Humana Press Inc., p. 193-201 9 p. (Methods in Molecular Biology; vol. 2032).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Dendritic Cells 100%
  • Bone Marrow 81%
  • Immune Tolerance 27%
  • Antigen-Presenting Cells 23%
  • Immune System 17%

• Evolving myelodysplastic syndrome in an HIV patient with history of anal cancer and chemotherapy

  Shi, M., Hu, X. & Chen, M., Dec 1 2019, In: Journal of Hematopathology. 12, 4, p. 213-214 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Anus Neoplasms 100%
  • Myelodysplastic Syndromes 81%
  • HIV 50%
  • Drug Therapy 42%
  • Chromosome Aberrations 23%

• Limits tumor relapse through triggering innate and adaptive immunity

  Liu, Z., Han, C., Dong, C., Shen, A., Hsu, E., Ren, Z., Lu, C., Liu, L., Zhang, A., Timmerman, C., Pu, Y., Wang, Y., Chen, M., Qiao, J. & Fu, Y. X., Aug 9 2019, In: Science Immunology. 4, 38, eaav6473.

  Research output: Contribution to journal › Article › peer-review

  • Adaptive Immunity 100%
  • Innate Immunity 90%
  • ErbB Receptors 66%
  • Recurrence 56%
  • Protein-Tyrosine Kinases 51%
  28 Scopus citations

• Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformation

  Gu, Z., Liu, Y., Cai, F., Patrick, M., Zmajkovic, J., Cao, H., Zhang, Y., Tasdogan, A., Chen, M., Qi, L., Liu, X., Li, K., Lyu, J., Dickerson, K. E., Chen, W., Ni, M., Merritt, M. E., Morrison, S. J., Skoda, R. C., Deberardinis, R. J., & 1 othersXu, J., 2019, In: Cancer discovery. 9, 9, p. 1228-1247 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Branched Chain Amino Acids 100%
  • Epigenomics 67%
  • Leukemia 26%
  • Neoplasms 24%
  • Myeloid Leukemia 13%
  103 Scopus citations

• Mutant p53 antagonizes p63/p73-mediated tumor suppression via Notch1

  Zhang, J., Sun, W., Kong, X., Zhang, Y., Yang, H. J., Ren, C., Jiang, Y., Chen, M. & Chen, X., Nov 26 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24259-24267 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Tumor Protein p73 85%
  • Neoplasms 49%
  • Longevity 45%
  • T-Lymphocytes 31%
  19 Scopus citations